Clinical trials: Perioperative Monitoring
Myocardial Ischemia
Perioperative Ischemia Reduction Study (PROSE) Pilot
After surgery, patients who have cardiogram changes consistent with a lack of oxygen to the heart muscles, also known as myocardial ischemia, have been found to have 9 times the chance of having an event such as a heart attack…
- Trial name
- NCT00665028
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Ottawa Hospital Research Institute
Perioperative Period, Cardiac Output
Cardiac Output in Children During Anesthesia
This study investigates cardiac output in young children under 18 months of age during the perioperative period by means of electrical cardiometry.
- Conditions
- Perioperative Period, Cardiac Output, Pediatric Anesthesia, Arterial Hypotension
- Trial name
- COC (NCT04044157)
- Testing
- non-invasive measurement of cardiac output
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- Laszlo Vutskits
Neuromuscular Blockade
Reversal of Neuromuscular Blockade and Perioperative Arrhythmias
Patients scheduled for elective abdominopelvic laparoscopic surgery under general anesthesia were included. Rocuronium was used for the neuromuscular blockade (NMB) and the level of NMB was monitored with train-of-four (TOF)…
- Trial name
- NCT04720573
- Testing
- Neostigmine, Sugammadex
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Gastric Adenocarcinoma, Pancreatic Adenocarcinoma
An Exercise and Nutrition Monitoring Intervention (Pt Pal) for the Improvement of Strength in Patients With Pancreatic or Stomach Cancer Receiving Chemoradiation Therapy Before Surgery, SurgeryStrong Study
This clinical trial studies the effectiveness of a home-based exercise and nutrition monitoring program called Pt Pal in improving strength in patients with pancreatic or stomach cancer receiving chemoradiation therapy before…
- Trial name
- NCT05056805
- Testing
- Aerobic Exercise, Dietary Intervention, Nutritional Intervention
- Sponsor
- M.D. Anderson Cancer Center
Observation, Postoperative
Proteomics and Physiological Parameters Predicting Complications After Colorectal Cancer Surgery
Study combines physiological data from wearables, continuous glucose montiors and proteomics to better assess risk of complications after colorectal surgery
- Trial name
- ProComp (NCT07494669)
- Testing
- Risk stratification with proteomics and data from wearables and CGMs
- Volunteers
- 210 people
- Sponsor
- Region Skane
Cardiopulmonary Bypass
TEG 6s® for Perioperative Monitoring of Platelet Function During Cardiopulmonary Bypass for Cardiac Surgery
Excessive bleeding is common during cardiopulmonary bypass (CPB) for cardiac surgery. This may result from the systemic activation of the coagulation pathway and the acquired platelet dysfunction during the procedure.
- Trial name
- TEG-PM (NCT04746560)
- Testing
- TEG®6S device with its Platelet mapping® cartridge
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Congenital Heart Disease in Children, Extracorporeal Circulation; Complications
Non-invasive Monitoring of Cerebral Autoregulation in Perioperative Neonatal Cardiac Surgery
Cardiac surgery under extracorporeal circulation (ECC) in newborns with congenital heart disease causes significant morbidity and mortality.
- Trial name
- NEMOCARD (NCT04295239)
- Testing
- MRI
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Nantes University Hospital
Diabetes Mellitus, Prediabetes
Perioperative Continuous Glucose Monitoring in Patients Undergoing an Abdominal Surgery
The purpose of this study it to assess whether the continuous glucose monitor system Dexcom G6® can be reliably used for perioperative glucose monitoring in 20 prediabetic or diabetic patients undergoing abdominal surgery in…
- Trial name
- GluPop (NCT03935919)
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Carotid Stenosis, Postoperative Cognitive Dysfunction
Neurocognitive Function After Carotid Thrombendarterectomy
Previous studies did not reach a consensus on the influence of the type of anesthesiologic procedure and monitoring, during carotid thrombendarterectomy, on perioperative complications and cognitive outcomes.
- Conditions
- Carotid Stenosis, Postoperative Cognitive Dysfunction, Neurological Impairment
- Trial name
- NCT05739357
- Testing
- NIRS, EEG
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- Clinical Hospital Centre Zagreb
The Episodes of Gastric Regurgitation
Gastroesophageal Regurgitation Under General Anesthesia
Gastric regurgitation increases the risk of pulmonary aspiration in surgical patients receiving general anesthesia because of depression of gastro-esophageal reflux.
- Trial name
- NCT02810912
- Testing
- the effect of surgical position
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Emergence Delirium in Pediatric Anesthesia, Perioperative Ketonemia and Its Association With Recovery Outcomes in Children
"KETOMED: Ketonemia and Risk of Emergence Delirium in Children Undergoing General Anesthesia - A Multicenter Observational Study"
The objective of this observational study is to evaluate the relationship between ketonemia and emergence delirium in children undergoing general anesthesia.
- Trial name
- KETOMED (NCT07249736)
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital Clínico Universitario de Valladolid
Perioperative Complication, Perioperative/Postoperative Complications
Continuous vs Intermittent Monitoring of Respiratory and Heart Rate in Relation to Length of Stay
Is heart rate and respiratory rate measured continuously with a new wireless sensor better as compared to standard care, with manually measured spot checks by nurses on general wards? Does continuous monitoring detect more…
- Conditions
- Perioperative Complication, Perioperative/Postoperative Complications, Surgery-Complications
- Trial name
- CIM-LOS (NCT06973044)
- Testing
- Checkpoint Cardio wireless continuous monitoring device
- Where
- 2 sites in Sweden
- Volunteers
- 46 people
- Sponsor
- Karolinska Institutet
Gastric Cancer
ctDNA-MRD Monitoring After Resection in Gastric Cancer
Numerous studies have demonstrated that circulating tumor DNA (ctDNA)-based molecular residual disease (MRD) detection has significant clinical value in postoperative recurrence monitoring, adjuvant treatment decision-making, and…
- Trial name
- MRD-GC (NCT06893133)
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Peking University
Non-Small Cell Lung Cancer
Evaluation ctDNA in Patients of Non-Small-Cell Lung Cancer Following Resection
Circulating tumor DNA (ctDNA) is a promising biomarker for noninvasive assessment of cancer burden. In this study, PEAC (Personalized Analysis of Cancer) technology was performed to detect the driver gene mutations from plasma…
- Trial name
- EVOLUTION (NCT04238130)
- Testing
- Perioperative ctDNA Dynamic Monitoring
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Sun Yat-sen University
Cardiac Surgery
IMMPRES: Intraoperative Monitoring & Management to Reduce Stroke
The objective of this study is to prospectively evaluate the therapeutic effectiveness of with blood pressure management using intraoperative neurophysiological monitoring with SSEP and EEG to reduce perioperative stroke.
- Trial name
- NCT04543838
- Testing
- Intervention, Standard of Care BP management
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Parthasarathy Thirumala
Mechanical Ventilation Complication, Postoperative Pulmonary Atelectasis
Perioperative Mechanical Ventilation and Postoperative Monitoring of IPI
This study evaluates the influence of alveolar recruitment maneuver, protocolized liberation from respiratory support and monitoring of Integrated Pulmonary Index on the duration of the mechanical ventilation and the number of…
- Trial name
- WEAN-IPI (NCT02524522)
- Testing
- INTELLiVENT-ASV mode, SIMV mode
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Northern State Medical University
Diabetes Mellitus, Dysglycemia
The Effect of Continuous Glucose Monitoring in Surgical Patients With Diabetes.
The goal of this randomised controlled trial to investigate the effect of continuous glucose monitoring (CGM) compared to standard point-of-care (POC) blood glucose measurements in surgical patients with diabetes in patients.
- Conditions
- Diabetes Mellitus, Dysglycemia, Perioperative Complication
- Trial name
- WARD-glucose (NCT06314061)
- Testing
- Dexcom G7 Continuous Glucose Monitoring (CGM) System (G7)
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Christian S. Meyhoff
Perioperative Myocardial Infarction, Perioperative Myocardial Injury
Monitoring of Vital Signs for Phenotyping of Perioperative Myocardial Infarction/Injury After Noncardiac Surgery
The goal of this observational prospective cohort study is to learn about the pathophysiology of perioperative myocardial infarction/injury in high-risk patients undergoing major non-cardiac surgery.
- Trial name
- PMI-VITAL (NCT05866874)
- Where
- Switzerland
- Volunteers
- 875 people
- Sponsor
- University Hospital, Basel, Switzerland
Central Venous Pressure
Central Venous Pressure Monitoring and Prognosis of High-risk Operating Patients
While central venous pressure measurement is used to guide fluid management in high risk surgical patients during perioperative period, the relationship between the value of central venous pressure and organ dysfunction and…
- Trial name
- NCT04596332
- Testing
- no intervention measures
- Volunteers
- 196 people
- Sponsor
- Fujian Provincial Hospital
Anesthesia Depth Monitoring, Analgesia Assessment
Target-Controlled Infusion (TCI) Effectiveness in Hysteroscopy
This prospective, randomized, observational study aims to evaluate the perioperative anesthetic efficacy of different Target-Controlled Infusion (TCI) models-specifically Minto, Schnider, and Eleveld pharmacokinetic models-in…
- Conditions
- Anesthesia Depth Monitoring, Analgesia Assessment, Perioperative Safety and Recovery, Target Controlled İnfusion
- Trial name
- NCT07023263
- Testing
- Schnider+ Mİnto, Eleveld
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Gazi University