Clinical trials: Periorbital
Wrinkle
A Safety and Effectiveness Study of the Tixel Device, (Fractional Peri-orbital Wrinkles Treatment ) Compared With Laser
This study is designed to explore the safety and the effectiveness of the Tixel device. This device performs fractional treatment of the skin by applying thermal (heat) energy to the skin.
- Trial name
- NCT03454672
- Testing
- Tixel, Laser
- Where
- 2 sites in United States, Israel
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Novoxel Ltd.
Facial Scarring
The Application of Intralesional 5-fluorouracil for the Management of Hypertrophic Facial Scars in the Periocular Region Resulting From Trauma and Surgical Procedures in Individuals Aged Over 18 Years
To determine the effectiveness of intralesional 5-fluorouracil in objectively reversing hypertrophic scars in the periocular region resulting from trauma or cosmetic surgery.
- Trial name
- AI5FMHFSPRFSOE (NCT07397520)
- Testing
- Intralesional administration of 5-fluorouracil
- Where
- Mexico
- Volunteers
- 7 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Wrinkles, Photoaging
Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines
This randomized, multi-center, double-blinded, placebo-controlled, split-face clinical trial was conducted to evaluate the procedure-pairing of OnabotulinumtoxinA with a peptide anti-aging serum to improve facial lines and…
- Conditions
- Wrinkles, Photoaging, Fine Lines
- Trial name
- NCT05089851
- Testing
- Onabotulinumtoxin A, Facial Cleanser, Facial Moisturizer
- Where
- 3 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Neurological Disorder, Nursing Caries
Effects of Cold Application and Heparinoid on Periorbital Edema and Ecchymosis
During surgery, blood leaking from damaged blood vessels spread to the periorbital area may cause periorbital edema and ecchymosis after anterior craniotomy.
- Conditions
- Neurological Disorder, Nursing Caries, Periorbital Edema, Ecchymosis
- Trial name
- NCT04119297
- Testing
- Routine care, Cold gel pack, Heparinoids Topical Cream
- Volunteers
- 90 people
- Sponsor
- Necmettin Erbakan University
Periorbital Wrinkles
Evaluation of the Safety and Performance of Epicare for the Treatment of Periorbital Wrinkles
This is a prospective, interventional, evaluator-blinded, multi-center clinical study designed to assess the safety and performance of the Epicare fractional nano-thulium (Tm:YAP 1938 nm) laser system for the treatment of…
- Trial name
- NCT07114562
- Testing
- Epicare
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laser team Ltd
Brow Ptosis, Lid Ptosis
Brow Lifting With Dysport
The purpose of this study is to provide data to assess Dysport™ injections as a treatment therapy for brow ptosis. This study will assess the outcome of brow lifting with use of Dysport.
- Trial name
- NCT01401803
- Testing
- Dysport
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kenneth Beer
Mild to Moderate Temporal Atrophy, Moderate to Severe Glabellar Rhytids
Upper Facial Remodeling With Perlane-L and Dysport
The purpose of this study is to provide data to support combination treatment of the upper face with Perlane-L® and Dysport™. This study will assess the outcome of upper face rejuvenation in the temporal fossa; outcome of…
- Conditions
- Mild to Moderate Temporal Atrophy, Moderate to Severe Glabellar Rhytids, Moderate to Severe Periorbital Rhytids
- Trial name
- DPL-2010 (NCT01354743)
- Testing
- Dysport, Perlane L
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beer, Kenneth R., M.D., PA
Wrinkles
Argireline in Treatment of Periorbital Wrinkles
The purpose of this study is to determine whether La Jolie gel is effective in the treatment of periorbital wrinkles.
- Trial name
- NCT01381484
- Testing
- 10% Argireline
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Intracranial Pressure, Intracranial Pressure Changes
Non-invasive Intracranial Pressure Estimation by Measurement of the Occlusion Pressure of the Isolated Periorbital Vein
Elevated intracranial pressure is a common complication of brain injury which means that the pressure within the skull rises above normal levels.
- Trial name
- NCT07222826
- Testing
- CPMX3
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Compremium AG
Facial Corrections, Facial Lines
A Study to Evaluate Satisfaction in Adult Participants With the Aesthetics of the Periorbital Area After JUVÉDERM® Fillers and BOTOX®/VISTABEL® Injections
Different studies have shown the negative effects of aging around the area of the eyes. Signs of aging may contribute to erroneously projected emotions (e.g., anger, tiredness, or sadness) that do not reflect the individual's…
- Trial name
- NCT05647551
- Testing
- BOTOX®/VISTABEL®, Juvéderm® VOLBELLA® with Lidocaine, Juvéderm® VOLIFT® with Lidocaine
- Where
- 8 sites in Australia, Belgium
- Volunteers
- 73 people
- Sponsor
- AbbVie
Age-related Changes in Skin Appearance and Physiology
Effect of Collagen Peptides on Skin Health: A Clinical Trial
The goal of this clinical trial is to evaluate whether daily oral supplementation with 2.5 g of specific bioactive collagen peptides (SCP) can improve skin physiology in healthy adult women aged 35-55 years.
- Trial name
- BCP-Skin (NCT07516756)
- Testing
- Specific Collagen Peptides
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Collagen Research Institute
Ocular Hypertension, Open Angle Glaucoma
Safety and Efficacy Study of JV-GL1 in Patients With Open-Angle Glaucoma or Ocular Hypertension
The aim of this research study is to assess the safety and feasibility of lowering intraocular pressure (IOP) using an experimental study drug, JV-GL1.
- Trial name
- NCT04761705
- Testing
- JV-GL1, Latanoprost 0.005% Ophthalmic Solution
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- JeniVision, Inc.
Periorbital Disorder
Influence of Sleep Quality in Patients With Periorbicular Hyperchromia
Periorbital hyperchromia (POH) or periorbital hyperpigmentation, commonly known as "dark circles", is a relatively common condition and a frequent reason for dermatological consultation.
- Trial name
- NCT03393624
- Where
- Brazil
- Volunteers
- 302 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Eyelid Diseases, Periorbital Disorder
The Role of Local Tranexamic Acid on Periorbital Oculoplastic Surgery
This study investigates the effect of tranexamic acid, a medication that helps reduce bleeding, in patients undergoing surgeries around their eyes.
- Conditions
- Eyelid Diseases, Periorbital Disorder, Hemorrhage, Surgical Blood Loss
- Trial name
- NCT05672407
- Testing
- Tranexamic acid
- Sponsor
- University of Miami
Periorbital Disorder
Carboxytherapy for Periorbital Dark Circles
the study evaluates carboxytherapy for the treatment of periorbital dark circles
- Trial name
- NCT04745078
- Testing
- Caboxy30, Caboxy60
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Early to Moderate Dry Age-Related Macular Degeneration
Study of Application of Transcutaneous Pulsed Electrical Stimulation Around Eye in Age-related Macular Degeneration
This study aims to evaluate the safety and efficacy of applying pulse electrical stimulation around eyes of age-related macular patients.
- Trial name
- NCT05259371
- Testing
- Transcutaneous Pulsed Electrical Stimulation (Device: Nu Eyne M02)
- Where
- 3 sites in South Korea
- Volunteers
- 25 people
- Sponsor
- Nu Eyne Co., Ltd.
Periorbital Hyperpigmentation
Topical Tranexamic Acid Versus Topical Vitamin C With Microneedling in Periorbital Hyperpigmentation; Comparative Study
Both vitamin C 20% and tranexamic acid 5mg/ml combined with microneedling were used for treatment of periorbital hyperpigmentation in a comparative pattern and both resulted in significant improvement of periorbital…
- Trial name
- NCT04697992
- Testing
- vitamin c 20%, Tranexamic acid 5mg/ml
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Glaucoma
Study of Application of Pulse Electrical Stimulation Around Eye in Glaucoma Patients
This study aims to evaluate the efficacy and safety of applying pulse electrical stimulation around eyes of glaucoma patients.
- Trial name
- NCT05159414
- Testing
- Pulse Electrical Stimulation
- Where
- South Korea
- Volunteers
- 18 people
- Sponsor
- Nu Eyne Co., Ltd.
Dry Eye Disease
Application of Pulse Electrical Stimulation Around Eye in Dry Eye Disease Patients Scheduled for LASEK Surgery
This study aims to evaluate the efficacy and safety of applying pulse electrical stimulation around eye in dry eye disease patients who are scheduled for LASEK surgery.
- Trial name
- NCT05271422
- Testing
- Real Pulse Electrical Stimulation (NuEyne 01)
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Nu Eyne Co., Ltd.
Skin Laxity
Post-Market Lower Eyelid Treatment With Renuvion in Greece
This is a prospective, multi-center, non-randomized, single-arm study of up to 15 subjects treated with the Renuvion APR System.
- Trial name
- NCT05605691
- Testing
- Renuvion APR System
- Where
- Greece
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Apyx Medical