Clinical trials: Peripheral Blood Flow
Memory Impairment
Cerebrovascular and Cognitive Improvement by Resveratrol (resVida) and Fruitflow-II (CCIRF-II)
The purpose of this study is to determine whether Fruitflow-II, Resveratrol (resVida), alone or in combination, are effective in the treatment of memory problems in adult patients with memory impairment.
- Trial name
- CCIRF-II (NCT01766180)
- Testing
- Fruitflow-II, resVida
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Neurolgy Institute for Brain Health and Fitness
Sedentary Behavior, Peripheral Circulation
Buerger-Allen Exercises and Peripheral Circulation in Sedentary Office Workers
This study aims to evaluate the acute effects of Buerger-Allen exercises on lower extremity circulation in sedentary office workers.
- Conditions
- Sedentary Behavior, Peripheral Circulation, Vascular Function
- Trial name
- BAE-CIRC (NCT07588893)
- Testing
- Buerger-Allen Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Ocular Physiology, Regional Blood Flow
Effects of Topical Clonidine vs. Brimonidine on Choroidal Blood Flow and Intraocular Pressure During Isometric Exercise
Brimonidine tartrate is an alpha-2 agonist ocular hypotensive drug that exerts its effect by causing both a decrease in aqueous production and an increase in uveoscleral outflow.
- Trial name
- NCT00312416
- Testing
- Clonidin, Brimonidine
- Where
- Austria
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Primary Open Angle Glaucoma
The Effects of Visior on Ocular Hemodynamics
To determine the relationship between the affects of viewing commercially available content through the VISIOR video goggles and ocular blood flow in glaucoma patients and healthy subjects.
- Trial name
- NCT02959593
- Testing
- VISIOR video goggles
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Visior Technologies Ltd.
Patent Foramen Ovale, Intrapulmonary Arteriovenous Anastamosis
Is Blood Flow Through IPAVA and PFO Related to Breath-hold and SCUBA Diving-induced Pulmonary Hypertension?
In summary, the investigators propose to study elite Croatian breath-hold and SCUBA divers. The investigators will quantify breath-hold hypoxia- and SCUBA diving-induced pulmonary hypertension and right heart function to…
- Trial name
- NCT03945643
- Testing
- Sildenafil
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Central Retinal Vein Occlusion
Retinal Blood Flow in Response to an Intravitreal Injection of Ranibizumab for Central Retinal Vein Occlusion (CRVO)
Ranibizumab (Lucentis, Genentech) is an off-label drug used for the clinical treatment of central retinal vein occlusion, which is one of the most common retinal vascular disorders.
- Trial name
- NCT01303276
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Arterial Stiffness, Healthy Lifestyle
Acute Effects of Autoregulated and Non-autoregulated Blood Flow Restrictive Exercise on Indices of Arterial Stiffness
To investigate the acute effects of autoregulated (AR) and non-autoregulated (NAR) BFR exercise on indices of arterial stiffness.
- Trial name
- NCT05719090
- Testing
- Delfi Personal Tourniquet Systems
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Salisbury University
Healthy
Measurement of Total Retinal Blood Flow During Flicker Stimulation in Healthy Subjects
Neurovascular coupling or functional hyperemia is defined as an essential physiologic mechanism in the brain, which is necessary for the local adaption of blood flow to altered metabolic demands of the tissue.
- Trial name
- NCT02531399
- Testing
- FDOCT, LDV, DVA
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Intraosseous Access, Infusion Rates
Infusion Flow Rates and Blood Sampling
To evaluate infusion flow rates attainable when using the proximal humerus and proximal tibia IO vascular access sites. To evaluate the intraosseous infusion physiology when using the proximal humerus and proximal tibia IO…
- Conditions
- Intraosseous Access, Infusion Rates, Intraosseous Blood, Venous Blood
- Trial name
- NCT02021617
- Testing
- Intraosseous access
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Vidacare Corporation
Cardiovascular Diseases
Cardiac Rehab and Cerebral Blood Flow Study
This study is being done to better understand the influence of cardiovascular disease on brain blood flow regulation and cognitive function, determine whether exercise-based cardiac rehabilitation can lead to better regulation of…
- Trial name
- NCT05012878
- Testing
- Cardiac rehabilitation - high intensity interval training (HIIT), Cardiac rehabilitation - moderate intensity continuous training (MICT), Cardiac rehabilitation - control
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Postspinal Hypotension, Pregnant Women Undergoing Cesarean Delivery
Carotid Flow Measurements in Pregnant Women
The goal of this observational study is to reveal the relation between carotid flow changes and post-spinal hypotension in pregnant women between the ages of 20-40.
- Trial name
- NCT06813989
- Testing
- carotid ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Cerebrovascular Circulation
Blood Brain Flow and Exercise
Cerebral vasodilator responses to CO2 will be measured in young healthy adults, healthy sedentary older adults, and healthy exercise trained older adults.
- Trial name
- NCT02653638
- Testing
- Control, Indomethacin
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Respiratory Muscle Blood Flow
Clinical Respiratory Evaluation Using Spectroscopy Trial
Respiratory muscles (the muscles used to breathe) need more blood (and oxygen) when their workload increases. It is difficult to measure respiratory muscle blood flow (RMBF) without invasive techniques.
- Trial name
- CREST (NCT01321411)
- Testing
- Near Infrared Spectroscopy
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Ocular Physiology, Microcirculation
Role of Adenosine in the Control of Choroidal Blood Flow During Changes in Ocular Perfusion Pressure.
Autoregulation is the ability of a vascular bed to maintain blood flow despite changes in perfusion pressure. For a long time it had been assumed that the choroid is a strictly passive vascular bed, which shows no autoregulation.
- Trial name
- NCT00712764
- Testing
- Adenosine
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Orthodontic Treatment
Curve of Spee: Speed of Leveling Using Different Orthodontic Archwires
The objectives if this study was to evaluate the efficacy of 3 different rectangular archwires in the correction of the curve of Spee (COS), to record the time needed to level excessive COS in the mandibular arch using the 3…
- Trial name
- NCT04549948
- Testing
- 0.017X0.025 Stainless steel, 0.019X0.025 Stainless steel, 0.021X0.025 B-Titanium archwire
- Where
- Jordan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Blood Flow Restriction Training
Effects of Short Duration Blood Flow Restriction Training on Musculoskeletal and Performance Outcomes
Effects of short duration blood flow restriction training on musculoskeletal and performance outcomes.
- Trial name
- NCT06406907
- Testing
- High Frequency Blood Flow Restriction Training Group, Low Frequency Blood Flow Restriction Training Group, High Frequency Blood Flow Restriction Training Instability Group
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Hypoxia, Hypercapnia
Impact of NOS, COX, and ROS Inhibition on Cerebral Blood Flow Regulation
Elucidating cerebrovascular control mechanisms during physiologic stress may help identify novel therapeutic targets aimed at preventing or reducing the impact of cerebrovascular disease.
- Trial name
- NCT03066115
- Testing
- L-NMMA, Ketorolac, Ascorbic Acid
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Microvascular Disease, Retinal Disease
Collecting Data on Retinal Blood Blood Flow and Blood Vessel Shape/Appearance Using an Investigational Device, XyCAM CRE, and to Then Compare Those Images With Images Collected From a Patient's Routine Clinical Examination.
The primary objective of the XyCAM CRE Camera Study is to evaluate retinal blood flow, choroidal blood flow, and retinal structural features and their association with the progression and characterization of retinal diseases…
- Trial name
- NCT07641738
- Testing
- XyCAM CRE Imaging
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Stuart Terry Eye Associates
Blood Flow
Microvascular Blood Flow During Passive Heating
Determine whether passive heating intervention effects microvascular blood flow as measured with near-infrared spectroscopy
- Trial name
- NCT06565221
- Testing
- Heat and negative pressure
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Sexual Dysfunction, Physiological
Vaginal Heat Wash-out (HWO) in 4 Groups of Women (Pre- and Postmenopausal With and Without Female Sexual Arousal Disorder (FSAD)).
The Pfizer developed Heat Wash-Out (HWO) system is a software controlled electromechanical system designed to measure vaginal wall blood flow. A small vaginal probe is attached to a control unit.
- Trial name
- FSAD HWO VBF (NCT00443248)
- Testing
- Vaginal Heat Wash-Out Device
- Where
- 2 sites in Australia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Pfizer