Clinical trials: Peripheral Nerve Decompression Injury
Carpal Tunnel Syndrome
Clinical Validation of a Decompression Prototype Splint for Patients With Carpal Tunel Syndrome
A multicentric randomized controlled trial has been designed to study the effects of a decompression prototype splint on symptoms, functional capacity and nerve conduction studies in patients with carpal tunnel syndrome.
- Trial name
- NCT04043780
- Testing
- Decompression prototype splint for carpal tunnel syndrome, Standard splint for carpal tunnel syndrome
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad de Zaragoza
Peripheral Nerve Injuries, Neuroma of Nerve Repair
High-Purity Type I Collagen Nerve Wrapping in Peripheral Nerve Procedures: A Prospective Registry
This prospective multicentre observational registry evaluates early clinical outcomes following the use of High-Purity Type I Collagen (HPTC) as a circumferential nerve wrap during peripheral nerve procedures.
- Conditions
- Peripheral Nerve Injuries, Neuroma of Nerve Repair, Nerve Graft; Complications, Mechanical, Peripheral Nerve Decompression Injury
- Trial name
- NCT07360730
- Testing
- High-Purity Type I Collagen (HPTC) Nerve Wrap
- Where
- 2 sites in India
- Volunteers
- 40 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Cubital Tunnel Syndrome, Peroneal Nerve Entrapment
Mechanomyography for Predictor of Prognosis in CuTS and PND Patients
The study will be a non-blinded two cohort design consisting only of symptomatic patients with CuTS or compressive peroneal neuropathy or in need of peroneal nerve decompression. The first cohort will be - patients with CuTS.
- Trial name
- NCT04322448
- Testing
- Mechanomyography (MMG)
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Washington University School of Medicine
Musculoskeletal Diseases, Median Nerve Disease
Comparison of Ultrasound-Guided Injection With Median Nerve Decompression Surgery in Carpal Tunnel Syndrome
The aim of this study is to compare ultrasound-guided perineural injection of the median nerve with classic minimal incision surgical technique for median nerve decompression in patients diagnosed with mild, moderate, and severe…
- Conditions
- Musculoskeletal Diseases, Median Nerve Disease, Carpal Tunnel Syndrome, Ultrasound-Guided Injection
- Trial name
- NCT06243848
- Testing
- Minimal Incision Surgery for median nerve decompression, Ultrasound-guided perineural injection with 5 cc 5% Dextrose
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Afyonkarahisar Health Sciences University
Carpal Tunnel Syndrome
A Comparison of Tissue Adhesive Material and Suture as Wound-closure Techniques Following Carpal Tunnel Decompression
Participants will be randomly assigned to suture-based wound closure (n=50) or tissue adhesive-based wound closure (n=50) with two-component skin adhesive Glubran Tiss 2®.
- Trial name
- NCT05747989
- Testing
- two-component skin adhesive, Glubran Tiss 2, skin is stitched with transcutaneous nylon sutures
- Where
- Croatia
- Volunteers
- 98 people
- Sponsor
- University of Split, School of Medicine
Carpal Tunnel Syndrome, Median Neuropathy
Hydrodissection With Neuroprolotherapy Versus Open Release for Carpal Tunnel Syndrome
This study is a randomized controlled, parallel-group, non-inferiority trial designed to compare ultrasound-guided hydrodissection combined with neuroprolotherapy versus open carpal tunnel release in patients with carpal tunnel…
- Trial name
- HN-CTS (NCT07576803)
- Testing
- Ultrasound-guided Hydrodissection of the Median Nerve, Open Carpal Tunnel Release
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Universidade Federal de Pernambuco
Carpal Tunnel Syndrome
WALANT Versus Local Anesthesia With Tourniquet for Carpal Tunnel Decompression
This multicenter, randomized, double-blinded controlled trial compared two local anesthetic techniques for open carpal tunnel decompression in adults.
- Trial name
- WALANT vs LA-T (NCT07617064)
- Testing
- WALANT technique for carpal tunnel decompression, Local anesthesia with tourniquet for carpal tunnel decompression
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Misr University for Science and Technology
Carpal Tunnel Syndrome
Minimal Invasive Carpal Tunnel Release With the Novel Device
This is a prospective, open-label, parallel-group, randomized controlled trial to evaluate the postoperative outcome after carpal tunnel release by using mini CTS releaser and open method with duration of 6 months estimated.
- Trial name
- NCT05067205
- Testing
- Carpal tunnel release surgery
- Where
- Taiwan
- Volunteers
- 41 people
- Sponsor
- Kaohsiung Medical University
Carpal Tunnel Syndrome
Post-Operative Splinting After Short-Incision Carpal Tunnel Release: a Prospective Study
This research study is for patients who are schedule to have carpal tunnel release surgery. The investigators have developed this study in order to determine if post-operative splinting is effective in improvement of patient…
- Trial name
- NCT01897272
- Testing
- Splinting
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Christine M. Kleinert Institute for Hand and Microsurgery
Cubital Tunnel Syndrome
SPY Angiography To Assist With Ulnar Nerve Transposition at the Elbow
Patients with vascular disease, thyroid disease or an allergy to indocyanine green (ICG) will be excluded. Patients with either median or ulnar nerve compression will be treated with nerve decompression.
- Trial name
- NCT05332405
- Testing
- Indocyanine green
- Where
- United States
- Sponsor
- NYU Langone Health
Carpal Tunnel Syndrome (CTS)
Open vs. Ultrasound-Guided Carpal Tunnel Release
Carpal Tunnel Syndrome (CTS) is the most prevalent entrapment neuropathy. Open Surgical Carpal Tunnel Release (OSCTR) remains the gold standard, while minimally invasive Ultrasound-Guided Carpal Tunnel Release (USGCTR) offers…
- Trial name
- NCT07814547
- Testing
- Open Surgical Carpal Tunnel Release (OSCTR), Ultrasound-Guided Carpal Tunnel Release (USGCTR)
- Where
- 2 sites in Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AUVA General Trauma Hospital Salzburg
Cubital Tunnel Syndrome, Ulnar Nerve Compression
Randomized Trial of Supercharged End-to-Side Anterior Interosseous Nerve Transfer for Severe Cubital Tunnel Syndrome
Functional motor recovery distal to a peripheral nerve lesion is predicated upon time to reinnervation of the motor end plate and the number of regenerate axons that reach the target.
- Conditions
- Cubital Tunnel Syndrome, Ulnar Nerve Compression, Ulnar Nerve Palsy, Ulnar Nerve Entrapment
- Trial name
- NCT04647058
- Testing
- Cubital tunnel release, Supercharged end-to-side (SETS) nerve transfer
- Where
- 2 sites in United States
- Sponsor
- Brigham and Women's Hospital
Humeral Fractures, Ulnar Nerve Compression
Simple Decompression Versus Anterior Transposition of the Ulnar Nerve
Both simple decompression and anterior transposition of the elbow nerve (ulnar nerve) for acute displaced fractures of the elbow (distal humerus) treated with plate fixation are currently used by surgeons.
- Trial name
- NCT01051869
- Testing
- Simple decompression, anterior subcutaneous transposition
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- Unity Health Toronto
Entrapment Neuropathy, Carpal Tunnel, Compression Neuropathy, Carpal Tunnel
Postoperative Alpha Lipoic Acid in the Carpal Tunnel Syndrome: a Randomized Controlled Trial.
The postoperative course of the decompression of the median nerve in the carpal tunnel syndrome can sometimes be complicated by pain, paresthesias and other unpleasant symptoms, or may be characterized by a slow recovery of nerve…
- Conditions
- Entrapment Neuropathy, Carpal Tunnel, Compression Neuropathy, Carpal Tunnel, Median Neuropathy, Carpal Tunnel
- Trial name
- NCT01895621
- Testing
- Median nerve decompression at the wrist, Alpha lipoic acid post median nerve decompression
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Istituto Ortopedico Rizzoli
Carpal Tunnel Syndrome (CTS), Lacertus Syndrome
MeDe Study: Comparing Median Nerve Decompression at the Carpal Tunnel Alone Versus Median Nerve Decompression at Both the Carpal Tunnel and Lacertus Fibrosis in Adults With Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is a condition that can cause pain, numbness, or tingling in the hand and wrist. The most common surgery for CTS is called carpal tunnel release, which aims to relieve pressure on the main nerve in…
- Trial name
- MeDe (NCT07594821)
- Testing
- Carpal tunnel release, Combined carpal tunnel and lacertus release
- Where
- 2 sites in Netherlands
- Volunteers
- 110 people
- Sponsor
- Maasstad Hospital
Cubital Tunnel Syndrome
Comparison of Different Surgical Treatments for Different Scales of Cubital Tunnel Syndrome
The purpose of this study is to determine which is the best surgery to treat different severity scales of cubital tunnel syndrome.
- Trial name
- NCT01893164
- Testing
- simple decompression, anterior subcutaneous transposition, anterior intramuscular transposition
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Jilin University
Recurrent Cubital Tunnel Syndrome, Recalcitrant Cubital Tunnel Syndrome
Nerve Protection Evaluation: Revision Cubital Tunnel Syndrome Decompression
This single-cohort, prospective case series is designed to evaluate and characterize the use of Axoguard HA+ Nerve Protector™ to protect the ulnar nerve in a first revision cubital tunnel decompression procedure.
- Trial name
- COVERED (NCT06117501)
- Testing
- Axoguard HA+ Nerve Protector™
- Where
- 7 sites in United States
- Volunteers
- 19 people
- Sponsor
- Axogen Corporation
Cubital Tunnel Syndrome
Electrical Nerve Stimulation of the Ulnar Nerve
Cubital tunnel syndrome is caused by compression of the ulnar nerve at the elbow. This leads to symptoms such as chronic hand weakness, numbness and pain.
- Trial name
- ESTIM (NCT02566616)
- Testing
- Ulnar Nerve Stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
Cubital Tunnel Syndrome
Comparing Surgical and Nonsurgical Outcomes of Cubital Tunnel Syndrome
Cubital tunnel syndrome is a condition that occurs when the ulnar nerve, which runs along the inside of the elbow, becomes irritated or compressed. It can cause pain, numbness, tingling, or weakness in the hand and arm.
- Trial name
- NCT07862543
- Testing
- Cubital tunnel release, Conservative Arm
- Where
- 7 sites in United States
- Volunteers
- 220 people
- Sponsor
- University of Pittsburgh