Clinical trials: Peripheral Nerve Disorder
Neuroblastoma, Brain Tumor
Efficacy of Prophylactic Itraconazole in High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation
The purpose of this study is to investigate whether the prophylactic use of itraconazole is a better option than empirical use of itraconazole in the management (prevention and treatment) of fungal infection associated with…
- Conditions
- Neuroblastoma, Brain Tumor, Retinoblastoma, Wilms Tumor
- Trial name
- NCT00336531
- Testing
- itraconazole
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
HTLV-1 Infection, HTLV I Associated Myelopathies
Dolutegravir Versus Dolutegravir in Combination With Tenofovir for the Treatment of HTLV-1 Infection
This phase 2b, open-label, randomized controlled trial evaluates the efficacy and safety of dolutegravir (DTG) alone versus dolutegravir combined with tenofovir disoproxil fumarate (TDF) in individuals with HTLV-1 infection and…
- Conditions
- HTLV-1 Infection, HTLV I Associated Myelopathies, HTLV I Associated T Cell Leukemia Lymphoma, Neuritis
- Trial name
- DOT-H (NCT07555431)
- Testing
- Combination of Dolutegravir + Tenofovir DF for treatment of HTLV-1 infection, Dolutegravir (DTG)
- Where
- Brazil
- Volunteers
- 146 people
- Sponsor
- Carlos Brites
Piriformis Syndrome, Corticosteroid Injection
Effect of Ultrasound-guided Piriformis Muscle Corticosteroid Injection Versus Extracorporeal Shock Wave Therapy for Piriformis Syndrome: a Randomized Control Trial
In this study, the investigators aim to compare the effect of extracorporeal shockwave therapy with ultrasound-guided piriformis coticosteroid injection in treatment of PS.
- Conditions
- Piriformis Syndrome, Corticosteroid Injection, Extracorporeal Shockwave Therapy, Therapeutic Exercise
- Trial name
- NCT04684537
- Testing
- Extracorporeal shockwave therapy (ESWT), Ultrasound-guided piriformis steroid injection
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Carpal Tunnel Syndrome
The Effect of High-intensity Laser Therapy in Patients With Carpal Tunnel Syndrome.
The aim of this study is to evaluate the effects of high intensity laser therapy (HILT) on pain, functional status, hand grip strength and median nerve cross-sectional area in ultrasonography in patients with carpal tunnel…
- Trial name
- NCT05678595
- Testing
- high-intensity laser therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Necmettin Erbakan University
Carpal Tunnel Syndrome
Dextrose, Steroid, PRP: Choosing the Right Injection for CRS Relief; a RCT
USG guided injections to relieve carpal tunnel syndrome with dextrose water or steroid or PRP
- Trial name
- NCT06349824
- Testing
- injection Dextrose water, USG machine
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sheikh Zayed Medical College
Breast Cancer, Chronic Myeloproliferative Disorders
Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon
RATIONALE: Beclomethasone may be an effective treatment for graft-versus-host disease. PURPOSE: Phase I/II trial to study the effectiveness of beclomethasone in treating patients who have graft-versus-host disease of the…
- Conditions
- Breast Cancer, Chronic Myeloproliferative Disorders, Gestational Trophoblastic Tumor, Graft Versus Host Disease
- Trial name
- NCT00010283
- Testing
- beclomethasone dipropionate
- Where
- United States
- Sponsor
- Fred Hutchinson Cancer Center
Chronic Neck Pain, Cervical Radiculopathy
Cervical Epidural Block in Chronic Neck Pain
Chronic neck pain can negatively affect daily activities, work ability, and quality of life. Cervical epidural block is commonly used to reduce pain and inflammation, while exercise and physical therapy aim to improve muscle…
- Trial name
- CNP-TREAT (NCT07787741)
- Testing
- Cervical Epidural Steroid Injection, Cervical Stabilization Exercise Program, Physical Therapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Alİ Eman, MD
Pain
Neuromodulation as a Treatment for Chemotherapy-Induced Peripheral Neuropathy
The goal of this clinical research study is to learn if using a type of non-invasive therapy called neurofeedback training can help teach patients with peripheral neuropathy how to change their own brain waves to lower their…
- Trial name
- NCT02573766
- Testing
- Neurofeedback Training, Electroencephalogram, Pain Scale
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- M.D. Anderson Cancer Center
Chronic Inflammatory Demyelinating Polyneuropathy
Hematopoietic Stem Cell Transplantation in Chronic Inflammatory Demyelinating Polyneuropathy
Chronic inflammatory demyelinating polyneuropathy is disease believed to be due to immune cells, cells which normally protect the body, but are now attacking the nerves in the body.
- Trial name
- NCT00278629
- Testing
- hematopoietic stem cell transplantation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwestern University
Carpal Tunnel Syndrome (CTS)
Comparative Outcomes of Endoscopic and Open Carpal Tunnel Release with Neurotrophic Supplementation in Severe Carpal Tunnel Syndrome
This study addresses the pressing clinical question of optimizing surgical and pharmacological interventions for severe Carpal Tunnel Syndrome (CTS), a prevalent and debilitating condition caused by median nerve compression.
- Trial name
- NCT06902831
- Testing
- Endoscopic Carpal Tunnel Release, Open carpal tunnel release, Neurotrophic supplementation
- Where
- Italy
- Volunteers
- 497 people
- Sponsor
- University of Bari
CIDP, Chronic Inflammation
Ultrasound-driven Stratification in CIDP
Chronic inflammatory demyelinating polyradiculoneuritis (CIDP) is a rare autoimmune neuropathy characterized by significant clinical and therapeutic heterogeneity.
- Conditions
- CIDP, Chronic Inflammation, Demyelinating Polyneuropathy
- Trial name
- TAILOR-CIDP (NCT07719153)
- Testing
- Refractory CIDP, Standard-of-care treatment for CIDP
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Breast Cancer, Melanoma
Ipsilateral Peripheral Intravenous Access Procedures (The iPIVAP Study)
This pilot study will examine facilitators and barriers that impact staff uptake for implementation of practice change involving ipsilateral IV insertion in patients with axillary lymphadenectomy/dissection in a single radiology…
- Conditions
- Breast Cancer, Melanoma, Thoracic Cancer, Lymphedema of Upper Arm
- Trial name
- iPIVAP (NCT04570722)
- Testing
- Ipsilateral peripheral IV insertion
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Duke University
Painful Diabetic Peripheral Neuropathy
High-frequency SCS Versus SCS in the Treatment of Diabetic Peripheral Neuropathic Pain
Application of High-Frequency Spinal Cord Stimulation (HF-SCS) in the Treatment of Painful Diabetic Peripheral Neuropathy (PDPN): A multicenter, randomized controlled study comparing its clinical efficacy with traditional spinal…
- Trial name
- NCT06158529
- Testing
- spinal cord stimulator, high frequency spinal cord stimulation
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Fan BiFa
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP), Multifocal Motor Neuropathy (MMN)
A Study of TAK-771 in Japanese Participants With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) and Multifocal Motor Neuropathy (MMN)
The main aim of the study is to check for side effects from TAK-771, and to check how well TAK-771 controls symptoms in Japanese participants with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and multifocal…
- Trial name
- NCT05084053
- Testing
- TAK-771
- Where
- 23 sites in Japan
- Volunteers
- 26 people
- Sponsor
- Takeda
Neonatal Brachial Plexus Palsy
Forced Lefthandedness in Neonatal Brachial Plexus Palsy (NBPP) Children
The aim of the project is to assess the neurophysiological and functional consequences of forced lefthandedness in a population with right neonatal brachial plexus palsy (NBPP).
- Trial name
- NBPP (NCT04376372)
- Testing
- Functional testing, Magnetic resonance imaging, Electromyography
- Where
- Belgium
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Complex Regional Pain Syndromes
Peripheral Nerve Injections for CRPS
Background Complex regional pain syndrome (CRPS) is characterized by intense pain, loss of function, and associated with motor, trophic, sudomotor, and/or vasomotor changes of the affected extremity.
- Trial name
- NCT04744675
- Testing
- Triamcinolone Acetonide 40mg/mL, Saline Injection, Bupivacaine
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Ottawa Hospital Research Institute
Chemotherapy Induced Peripheral Neuropathy (CIPN), Neuropathic Pain
Evaluation of Effectiveness of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy for Treatment of Chemotherapy Induced Peripheral Neuropathy
The goal of this observational study is to learn about the effectiveness of closed-loop spinal cord stimulation (CL-SCS) therapy for treatment of painful chemotherapy induced peripheral neuropathy.
- Trial name
- CIPRESS (NCT07304401)
- Where
- 5 sites in Netherlands
- Volunteers
- 20 people
- Sponsor
- Rijnstate Hospital
Chronic Myeloproliferative Disorders, Graft Versus Host Disease
Immunologic Diagnostic Blood Test in Predicting Side-Effects in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Other Diseases
RATIONALE: Studying a diagnostic biomarker test in blood samples from patients who have undergone a donor stem cell transplant for cancer may help doctors plan treatment.
- Conditions
- Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Infection, Leukemia
- Trial name
- NCT00813501
- Testing
- immunosuppressive therapy, immunological diagnostic method, allogeneic hematopoietic stem cell transplantation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- City of Hope Medical Center
Low Back Pain
Fatty Infiltration in Paraspinal Muscles and Lumbar Erector Spina Plane Block
This study aimed to investigate the relationship between fatty infiltration in the lumbar paraspinal (multifidus and erector spinae) muscles, clinical characteristics, and treatment response after lumbar erector spinae plane…
- Trial name
- NCT06208865
- Testing
- lumbar erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 147 people
- Sponsor
- Diskapi Teaching and Research Hospital
Disc Herniation With Radiculopathy
A Randomized Trial Comparing SpineJet® Hydrodiscectomy to Open Lumbar Microdiscectomy for Treatment of Lumbar Radiculopathy Due to Disc Herniation
The purpose of this study is to compare a standard surgical procedure, open surgical microdiscectomy, used primarily to relieve leg pain and repair disc herniation to a newer surgical procedure, hydrodiscectomy with Spinejet®.
- Trial name
- NCT00384007
- Testing
- Hydrodiscectomy with Spinejet
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Pinnacle Pain Medicine
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