Clinical trials: Peripheral Nerve Disorder
Carpal Tunnel Syndrome
Evaluation of the MANOS Carpal Tunnel Release System in Patients With Carpal Tunnel Syndrome
The MANOS device is a carpal tunnel blade used to perform carpal tunnel release (CTR). CTR is indicated for the treatment of Carpal Tunnel Syndrome when conservative therapy fails.
- Trial name
- NCT01450735
- Testing
- MANOS CTR™
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Thayer Intellectual Property, Inc.
Dizziness
Vestibular Evaluation After Vestibular Schwannoma Treatment
Vestibular schwannoma is a benign tumor located on the vestibular nerve. Patient could present dizziness symptoms cause to the tumor, and at least after the treatment by gamaknife radiosurgery or microsurgery resection.
- Trial name
- EVTSVCGEC (NCT03670589)
- Testing
- Radiosurgery gammaknife, Microsurgery resection
- Where
- France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Grenoble
Neuropathic Pain
Effect of Multitarget tDCS for Neuropathic Pain
This study aims to conduct a randomized controlled trial to evaluate the effect of multitarget transcranial direct current stimulation (tDCS) on pain, depression, anxiety, quality of life and sleep, in patients with neuropathic…
- Trial name
- NCT06510725
- Testing
- Multitarget tDCS, Single-target tDCS
- Where
- 3 sites in China
- Volunteers
- 204 people
- Sponsor
- Xuanwu Hospital, Beijing
Knee Osteoarthritis, Pressure Ulcer
Pressure Ulcers in Knee Replacement Surgery
From the point of view of nursing to know exactly the different risk factors for the onset of pressure ulcers is very important as it allows to accurately orient preventive care interventions.
- Trial name
- peripress (NCT03039153)
- Where
- Italy
- Volunteers
- 565 people
- Sponsor
- Istituto Ortopedico Rizzoli
Diabetic Peripheral Neuropathy
Use of Topical Lidocaine to Reduce Pain in Patients With Diabetic Neuropathy
The purpose of this study is to see if an investigational drug known as the lidocaine 5% patch is safe and effective in reducing the symptoms of diabetic neuropathy, to examine how topical lidocaine affects the nerve endings, and…
- Trial name
- NCT01086150
- Testing
- Skin biopsy, Lidocaine 5% patches
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Cervical Radiculopathy
Mulligan Mobilization & Stretching Effects of Cervical
1. To evaluate the effectiveness of mulligan mobilization and stretching exercises in reducing pain in individuals with cervical radiculopathy. 2.
- Trial name
- NCT07045974
- Testing
- Group A-Mulligan Mobilization, Group B-Stretching Exercises
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Familial Dysautonomia (Riley-Day Syndrome), Hereditary Sensory and Autonomic Neuropathies
The Natural History of Familial Dysautonomia
The study will collect clinical information from patients with FD and allow them to give blood to help develop biological markers of the disease to aid diagnosis and treatment.
- Conditions
- Familial Dysautonomia (Riley-Day Syndrome), Hereditary Sensory and Autonomic Neuropathies, Hereditary Sensory and Autonomic Neuropathy 3
- Trial name
- NCT03920774
- Where
- 2 sites in United States, Israel
- Volunteers
- 400 people
- Sponsor
- NYU Langone Health
Polyneuropathies, Septic Shock
Electrical Muscle Stimulation in the Development of Acquired Weakness in Patients With Severe Sepsis and Septic Shock
The aim of this study is to compare the effect of EMS and conventional physical therapy on strength and muscle mass and development in adult patients with severe sepsis and septic shock.
- Conditions
- Polyneuropathies, Septic Shock, Muscle Weakness
- Trial name
- NCT03765489
- Testing
- electrical muscle stimulation, conventional physical therapy
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Chile
Morton Neuroma
Blind and Ultrasound Guided Injection in Morton Neuroma
The aim of this work trial is to compare the effectiveness of blind and ultrasound guided injection for Morton neuroma in order to determine which is more appropriate as the initial procedure in conservative treatment
- Trial name
- NCT03046108
- Testing
- blind injection of Morton neuroma, blind injection of Mepivacaine, blind injection of Triamcinolone
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Complejo Hospitalario Universitario de Granada
Cancer
Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment
RATIONALE: Caspofungin acetate or amphotericin B liposomal may be effective in preventing or controlling fever and neutropenia caused by chemotherapy, bone marrow transplantation, or peripheral stem cell transplantation.
- Trial name
- NCT00008359
- Testing
- caspofungin acetate, liposomal amphotericin B
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Spinal Cord Injury, Paralysis
A Neuroprosthesis for Prolonged Standing After SCI Using Multi-Contact Peripheral Nerve Electrodes
The purpose of this study is to improve the performance of neuroprosthesis for standing after SCI by developing and testing new advanced methods that use multiple contact peripheral nerve electrodes to slow the onset of fatigue…
- Conditions
- Spinal Cord Injury, Paralysis, Tetraplegia, Paraplegia
- Trial name
- NCT01923662
- Testing
- IST-16 (16-Channel implanted stimulator-telemeter
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- VA Office of Research and Development
Healthy Adult Participants
Safety, Tolerability and Pharmacokinetics of Oral Ketamir-2 in Healthy Adult Subjects
This is a prospective, randomized, double-blind, placebo-controlled study designed to evaluate the safety, tolerability, and pharmacokinetics of oral Ketamir-2 in healthy adult participants.
- Trial name
- NCT07791303
- Testing
- Ketamir-2
- Where
- Israel
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- MIRA Pharmaceuticals
Neuropathic Pain From Spinal Cord Injury, Diabetic Peripheral Neuropathy
Validation Study of Neuropathic Pain
This study seeks to validate clinically evoked or obtained objective pain signs with the patient's corresponding quantified subjective pain symptoms.
- Conditions
- Neuropathic Pain From Spinal Cord Injury, Diabetic Peripheral Neuropathy, Post Herpetic Pain
- Trial name
- NCT00623961
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Wisconsin, Madison
Breast Cancer Female
Chemotherapy - Induced Peripheral Neuropathy
The purpose of this study was to examine the efficacy of cryotherapy with frozen gloves for the prevention of the chemotherapy-induced peripheral neuropathy (CIPN) of the hand.
- Trial name
- NCT05138042
- Testing
- Cryotherapy (frozen glove)
- Where
- Taiwan
- Volunteers
- 22 people
- Sponsor
- Chung Shan Medical University
Chemotherapy-induced Peripheral Neuropathy
A Study of Topical Pirenzepine or Placebo in Oncology Patients With Chemotherapy Induced Peripheral Neuropathy
This is a randomized, double-blind, placebo-controlled adaptive study of the safety, tolerability, and exploratory efficacy of once-daily topical WST-057 administered for up to 19 weeks (or up to 24 weeks for subjects who…
- Trial name
- NCT05488873
- Testing
- WST-057 Active
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- WinSanTor, Inc
Spinal; Nerve Root, Pain, Pelvic Pain
Quality of Life and Pain Changes Due to DRG Stimulation for Chronic Pain
ACTIVE study- a prospective observational clinical study examining the changes in quality of life and pain following dorsal root ganglion stimulation for the treatment of chronic intractable pelvic and lower limb pain.
- Conditions
- Spinal; Nerve Root, Pain, Pelvic Pain, Regional Pain Syndrome, Chronic Pain Syndrome
- Trial name
- ACTIVE (NCT03417973)
- Testing
- dorsal root ganglion neuromodulation
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- KM Clinical Research Group
Diabetic Neuropathy, Painful
Study Of Pregabalin (Lyrica) In Patients With Painful Diabetic Peripheral Neuropathy
Patients will be switched from their current medication for painful diabetic peripheral neuropathy to evaluate the safety and efficacy of pregabalin as compared to placebo.
- Trial name
- NCT01057693
- Testing
- pregabalin (Lyrica)
- Where
- 172 sites in United States, Canada and 2 more
- Volunteers
- 633 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Cervical Radiculopathy
McKenzie Exercises Along With Neurodynamic Mobilization Exercises in Patients With Cervical Radiculopathy
This studt was conducted to determine the effects of McKenzie Exercises along with Neurodynamic Mobilization exercises on Pain, Range of Motion and Functional Disability in patients with Cervical Radiculopathy.
- Trial name
- NCT07426614
- Testing
- Neural Mobilization exercises:, Standard Treatment, McKenzie Exercises
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Cardiac Amyloidosis
PET Imaging With [18F]Fluselenamyl in People With Cardiac Amyloidosis
This observational study will evaluate the imaging performance of the investigational positron emission tomography (PET) radiotracer[18F]Fluselenamyl (FSA) in individuals with cardiac amyloidosis.
- Trial name
- FSA-CA (NCT07771621)
- Testing
- [18F]Fluselenamyl (FSA)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington University School of Medicine
Carpal Tunnel Syndrome, Pain
Staged Bilateral Carpal Tunnel Release: Which Side Hurts More?
Title Staged Bilateral Carpal Tunnel Release: Which Side Hurts More? Primary null hypothesis Patients undergoing staged bilateral open Carpal Tunnel Release (CTR) have no difference in overall pain intensity of pain between…
- Trial name
- NCT02198521
- Where
- United States
- Sponsor
- Massachusetts General Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.