Clinical trials: Peripheral Nerves US
Healthy
The Effect of Different Doses (Mass) of Local Anesthetic on Duration of Adductor Canal Block in Healthy Volunteers - Part 2
To investigate whether increased dose of local anesthetic (lidocaine) increases duration of peripheral nerve block (adductor canal block) and to develop a model for assessing duration of peripheral nerve blockades.
- Trial name
- NCT02172729
- Testing
- Adductor canal block with 20 ml lidocaine, single bolus
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Ultrasound Imaging of Anatomical Structures
A Study to Evaluate the Performance and Potential Benefits of an Assistive Artificial Intelligence Device ScanNav Anatomy Peripheral Nerve Block - US V1.0 for Ultrasound-guided Regional Anesthesia
This is a single-center, prospective study to be undertaken at University of Oregon, Portland, USA. The aim is to provide data on the clinical performance of ScanNav Anatomy PNB for identification of anatomical structures during…
- Trial name
- NCT04918693
- Testing
- Ultrasound scanning
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- IntelligentUltrasound Limited
Injury of Median Nerve Distal to Forearm, Carpal Tunnel Syndrome
Median Nerve Injury in US-guided Carpal Tunnel Injections
Carpal tunnel syndrome (CTS) is the most common nerve compression disorder in the upper extremity. It can be treated with surgical or nonsurgical methods.
- Trial name
- NCT03391336
- Where
- Taiwan
- Volunteers
- 126 people
- Sponsor
- yi-chih HSU
Orthopedic Surgery
Monitoring of Intensity of Stimulation and Injection Pressure in US Guided Peripheral Nerve Block According to Anatomic Needle Type Position
The purpose of the study is define the minimal intensity of stimulation range at which the needle is closed to the nerve without penetrating its surface (epineurium layer) in ultrasound guided peripheral nerve blockade
- Trial name
- NCT03430453
- Testing
- Measure of the minimal intensity of stimulation during ultrasound guided peripheral nerve blockade
- Where
- 9 sites in France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Montpellier
Healthy
ED95 of Lidocaine 1.0% for Filling the Adductor Canal
The aim of this prospective dose finding study is to estimate the minimal effective volume (ED95) for lidocaine 1.0% for filling the adductor canal when placing an adductor canal block.
- Trial name
- NCT02033356
- Testing
- Adductor canal block with lidocaine 1%, Lidocaine
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Carpal Tunnel Syndrome, Physical Therapy Modalities
Pulsed US Versus SWD in Carpal Tunnel Syndrome
The goal of this clinical trial is to compare two physical therapy treatments in people with mild-to-moderate carpal tunnel syndrome (CTS). CTS is a condition that causes pain, numbness, and weakness in the hand.
- Conditions
- Carpal Tunnel Syndrome, Physical Therapy Modalities, Ultrasound Therapy
- Trial name
- NCT07545161
- Testing
- Pulsed Therapeutic Ultrasound, Pulsed Shortwave Diathermy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Guillain Barré Syndrome, Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Our Study Aims to Determine if Nerve Alterations in Acute GBS and CIDP Detectable by Ultrasound Match Electrodiagnostic Findings and if This Method Aids Early Diagnosis, Predict Their Outcomes and Differentiate Between Axonal and Demyelinating Subtypes.
Neuromuscular ultrasound (NMUS) is emerging as a valuable non-invasive diagnostic tool. In GBS, NMUS can detect proximal nerve enlargement early, before neurophysiological changes.
- Conditions
- Guillain Barré Syndrome, Chronic Inflammatory Demyelinating Polyradiculoneuropathy, Peripheral Nerve Disorder, Peripheral Nerves US
- Trial name
- NCT06615622
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Healthy Volunteers
Does Perineural Dexamethasone Prolong Duration of a Nerve Block?
The purpose of this study is to investigate whether dexamethasone as an adjuvant to ropivacaine for adductor canal block increases duration of the sensory block, when controlling for a systemic effect using a paired design and…
- Trial name
- NCT02351804
- Testing
- Ropivacaine + dexamethasone
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Peripheral Nerve Block
Determination of the Sensitivity, Specificity & Receiver Operating Characteristic of Nerve Stimulation Receptor as a Decision-making Tool During US Guided PNB
Although the superiority of ultrasound guidance over neurostimulation (NS) has been demonstrated, it has its limits, namely when used for a deeper block (device limits) or if used by a less experienced operator (ability to…
- Trial name
- NCT05190302
- Where
- Canada
- Volunteers
- 115 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Nerve Block, Efficiency
Femoral Nerve Blockade 7.5 ml of 1% Lidocaine: US Guidance Versus US Guidance With Electrical Stimulation of Peripheral Nerves (Influence of the Femoral Nerve Blockade on the Effectiveness of Small Doses of Local Anesthetic.). (EPBwEPN)
In modern anesthesiology, peripheral nerve blocks are performed using ultrasound control and electrical stimulation of peripheral nerves (PEN), or only ultrasound control or only EPN.
- Conditions
- Nerve Block, Efficiency, Femoral Nerve, Ultrasonography
- Trial name
- NCT05209711
- Testing
- Femoral nerve block under ultrasound control with a electrostimulator peripheral nerves 7.5 ml 1% lidocaine, Femoral nerve blockade under ultrasound control without a peripheral nerve stimulator 7.5 ml 1% lidocaine
- Where
- Belarus
- Volunteers
- 40 people
- Sponsor
- Mogilev Regional Clinical Hospital
Nerve Block, Efficiency
Sciatic Nerve Blockade by Subgluteal Access 12.5 ml of 1% Lidocaine: US Guidance Versus US Guidance With Electrical Stimulation of Peripheral Nerves (Influence of the Sciatic Nerve Blockade on the Effectiveness of Small Doses of Local Anesthetic.).
In modern anesthesiology, peripheral nerve blocks are performed using ultrasound control and electrical stimulation of peripheral nerves (PEN), or only ultrasound control or only EPN.
- Conditions
- Nerve Block, Efficiency, Sciatic Nerve, Ultrasonography
- Trial name
- EPBwEPN (NCT05205473)
- Testing
- Sciatic nerve block under ultrasound control with a electrostimulator peripheral nerves 12.5 ml 1% lidocaine, sciatic nerve blockade under ultrasound control without a peripheral nerve stimulator 12.5 ml 1% lidocaine
- Where
- Belarus
- Volunteers
- 40 people
- Sponsor
- Mogilev Regional Clinical Hospital
Charcot-Marie-Tooth, CMT1A
Studying Nerve Function and Structure in Charcot-Marie-Tooth Disease, Anti-MAG Neuropathy and CIDP
The project aims to perform both conventional nerve-conduction studies and axonal-excitability assessments using the TRONDF protocol in patients with selected forms of Charcot-Marie-Tooth disease, with comparison to individuals…
- Conditions
- Charcot-Marie-Tooth, CMT1A, Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Polyneuropathy Associated With Anti-MAG Antibodies (Anti-MAG Polyneuropathy)
- Trial name
- CMT-NFS (NCT07461896)
- Where
- Italy
- Volunteers
- 39 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Muscle Strength, Healthy Volunteers
Adductor Canal Block and Effect of 10 Versus 30 ml Ropivacaine on Muscle Strength: a Randomized Study in Healthy Volunteers
To investigate whether reducing the volume (30 versus 10 ml) ropivacaine injected can reduce the number of subjects with impaired muscle strength following adductor canal block.
- Trial name
- NCT01981746
- Testing
- Adductor canal block with ropivacaine 0.1%
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Ulnar Nerve Compression
US and Shear Wave Elastography in Cubital Tunnel Syndrome
This study aims to assess the role of US and SWE in diagnosis of CuTS and localization of its underlying etiology and verifying whether it can be diagnosed and graded based on US findings, especially quantitaive ulnar nerve…
- Trial name
- NCT06090877
- Testing
- US and shear wave elstography
- Volunteers
- 50 people
- Sponsor
- Assiut University
Carpal Tunnel Syndrome, CTS
Registry of the Patient Experience for Carpal Tunnel Release
Multi-center study to collect large scale, multidimensional real-world data on patients undergoing carpal tunnel release (CTR).
- Trial name
- MISSION (NCT06071468)
- Testing
- UltraGuideCTR (Device) with Ultrasound Guided Carpal Tunnel Release (CTR-US), Endocscopic CTR, Open CTR
- Where
- 33 sites in United States
- Volunteers
- 1,424 people
- Sponsor
- Sonex Health, Inc.
Neurofibromatosis Type 1, Plexiform Neurofibromas
US Selumetinib Registry
The purpose of this study is to understand treatment patterns and assess long-term effectiveness and safety outcomes associated with selumetinib treatment as well as to explore clinical and non-clinical factors affecting those…
- Trial name
- NCT05683678
- Where
- 10 sites in United States
- Volunteers
- 37 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Ultrasound Imaging of Anatomical Structures
A Study to Collect Imaging Data for the Validation of the Intelligent Ultrasound's ScanNav Anatomy Peripheral Nerve Block (PNB) - US v1.0
This is a single-center, prospective study to be undertaken at University of Oregon, Portland, USA. The aim is to evaluate the clinical performance of ScanNav Anatomy PNB when highlighting anatomical structures during UGRA…
- Trial name
- NCT04906018
- Testing
- Ultrasound scans
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IntelligentUltrasound Limited
Carpal Tunnel Syndrome, CTS
Multicenter Prospective Trial of Office-based Carpal Tunnel Release With Ultrasound Guidance (ROBUST)
Multicenter prospective single-arm trial of subjects with symptomatic Carpal Tunnel Syndrome treated with Ultrasound Guided Carpal Tunnel Release (CTR-US) in an office-based setting.
- Trial name
- ROBUST (NCT05675046)
- Testing
- Carpal Tunnel Release with Ultrasound Guidance using the UltraGuideCTR device
- Where
- 7 sites in United States
- Volunteers
- 149 people
- Sponsor
- Sonex Health, Inc.
Anesthesia, Pain
A Comparison of US and Evoked Motor Response-guided Placement of Continuous Femoral Nerve Block Following TKA
The purpose of this study is to determine which technique for catheter placement in continuous femoral nerve block (FNB) is most successful - guidance with (1) ultrasound or (2) nerve stimulation and ultrasound.
- Conditions
- Anesthesia, Pain, Nerve Pain, Knee Arthroplasty
- Trial name
- NCT03121976
- Testing
- Ultrasound, Ultrasound + Nerve Stimulation
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- Sunnybrook Health Sciences Centre
Sciatic Nerve AH, Peripheral Nerves US
Ultrasound Description of the Sciatic Nerve
Sciatic nerve blocks are frequently used for anesthesia or analgesia for surgery of the lower legs. Currently, if ultrasound is used to find the sciatic nerve, the leg must be raised to locate the nerve with the ultrasound probe…
- Trial name
- NCT00663715
- Testing
- Observation of the Sciatic Nerve
- Sponsor
- Children's Hospital of Philadelphia