Clinical trials: Peripheral Neuropathy Pain
Diabetic Peripheral Neuropathy
Peripheral Nerve Responses to Focal Vibration and Implications in Pain and Mobility for Patients With Diabetic Peripheral Neuropathy
The purpose of this study is to characterize the changes in peripheral nerve functions (sensory and motor) in patients with diabetic peripheral neuropathy, and examine the relations between the changes in nerve functions and…
- Trial name
- NCT05041816
- Testing
- Focal vibration therapy
- Where
- United States
- Sponsor
- University of Oklahoma
Chronic Radicular Back Pain, Lumboischialgia
High-tone External Muscle Stimulation for Pain Reduction
Sciatica is a common pain problem that affects not only the patient but also constitutes a socioeconomic burden and thus affects the whole society. So far, current pharmacologic therapies are inadequate for many patients.
- Conditions
- Chronic Radicular Back Pain, Lumboischialgia, Cervico Brachialgia
- Trial name
- HTEMS (NCT02151565)
- Testing
- HTEMS, TENS
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- West German Center of Diabetes and Health
Cervical Radiculopathy
Effectiveness of Cervical Traction and Neural Mobilization in Patients With Cervical Radiculopathy
The purpose of the study is to examine the effects of cervical traction with or without the addition of neural mobilization, in patients with cervical radiculopathy
- Trial name
- NCT03015493
- Testing
- Neural mobilization combined with traction, Traction
- Volunteers
- 50 people
- Sponsor
- Christos Savva
Neuralgia, Postherpetic
RN624 For Pain Of Post-Herpetic Neuralgia
This study will test the efficacy and safety of two doses levels of RN624 versus placebo for the relief of pain caused by post-herpetic neuralgia (PHN).
- Trial name
- NCT00568321
- Testing
- RN624
- Where
- 31 sites in United States
- Volunteers
- 99 people
- Sponsor
- Pfizer
Cluneal Syndrome
Proximal Versus Distal Superior Cluneal Nerve Block in Entrapment Neuropathy
Superior cluneal nerve (SCN) entrapment is an underdiagnosed cause of chronic low back and gluteal pain. Although diagnostic nerve block is considered the gold standard for confirming SCN entrapment, there is no consensus…
- Trial name
- NCT07372430
- Testing
- Ultrasound-guided distal superior cluneal nerve injection, Ultrasound-guided proximal superior cluneal nerve injection
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Nerve Entrapment Syndrome, Radiofrequency Ablation
Radiofrequency Ablation of the Superior Cluneal Nerve
Low back pain is one of the most common musculoskeletal disorders affects individuals at least one during lifetime. Chronic low back pain (CLBP) lasts more than 3 months and decreases quality of life and causes work loss all over…
- Conditions
- Nerve Entrapment Syndrome, Radiofrequency Ablation, Low Back Pain
- Trial name
- NCT06240000
- Testing
- Radiofrequency ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Ankara City Hospital Bilkent
Carpal Tunnel Syndrome, Depressive Symptoms
The Relationship of Psychological Factors and Sleep Quality With the Severity of Carpal Tunnel Syndrome
The most common entrapment neuropathy symptoms, the diagnosis of CTS, is determined by examination findings and by means of the results of electro-diagnostic test.
- Conditions
- Carpal Tunnel Syndrome, Depressive Symptoms, Sleepiness, Anxiety
- Trial name
- NCT05047367
- Testing
- cross-sectional survey study
- Where
- Turkey (Türkiye)
- Volunteers
- 149 people
- Sponsor
- Cumhuriyet University
Lumbar Disc Herniation With Radiculopathy, Sciatica
FINDISC-Pain, Finnish Discectomy Trial on the Benefits and Harms of Surgery in Patients With Lumbar Disc Herniation
The FINDISC trial studies whether common back operation, microdiscectomy, is effective and safe for treating sciatica caused by a lumbar disc herniation.
- Trial name
- FINDISC-Pain (NCT07418944)
- Testing
- Microdiscectomy
- Where
- Finland
- Volunteers
- 122 people
- Sponsor
- Helsinki University Central Hospital
Carpal Tunnel Syndrome
Cross-Cultural Adaptation and Psychometric Validation of the Turkish Version of Atroshi-Lyrén 6-item Symptoms Scale
This study aims to develop Turkish version of the Atroshi-Lyrén 6-item symptoms scale (A-L scale) and to perform validity and reliability evaluations.
- Trial name
- NCT05970692
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ilke KARA
Neuropathy, Diabete Mellitus
Comparison of Active vs Passive Neural Mobilizations Effects in Improving Burning Pain, Muscular Strength, and Range of Motion in Patients With Diabetic Neuropathy
Randomized controlled trial evaluating active and passive neurodynamic techniques for diabetic neuropathy. Sample size: 60 patients (30 per group), aged 40 to 65 years, diagnosed with diabetes mellitus.
- Conditions
- Neuropathy, Diabete Mellitus, Diabetic Neuropathy
- Trial name
- RCT (NCT07141992)
- Testing
- Active Neural Mobilzations, Passive Neural Mobilzations
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Neuralgia, Postherpetic
Safety and Efficacy of Gabapentin in Postherpetic Neuralgia
Gabapentin and pregabalin are treatments for some types of neuropathic pain, including postherpetic neuralgia (PHN). However, these treatments usually need to be taken 3 times a day for effective pain control.
- Trial name
- NCT00335933
- Testing
- Gabapentin extended-release tablets
- Where
- United States
- Volunteers
- 378 people
- Sponsor
- Depomed
Diabetes Mellitus, Neuropathic Pain
A Study of Intra-dermal Injection of Botulinum Toxin Type A for the Diabetic Neuropathic Foot Pain
Effective treatment of neuropathic foot pain in diabetic patients is very important to improve their quality of life. There are many medications used to reduce the diabetic neuropathic pain, including anticonvulsants…
- Trial name
- NCT00336349
- Testing
- Botulinum Toxin Type A
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University Hospital
Limb Ischemia, Low Back Pain
Comorbidity Screening and Referral by Prosthetists
Lower-limb amputation is associated with life-altering and life-limiting comorbidities. Currently, onus is on primary care providers to diagnose, educate, and refer patients for appropriate management.
- Conditions
- Limb Ischemia, Low Back Pain, Depression, Neuropathy;Peripheral
- Trial name
- NCT05410548
- Testing
- Standard-of-Care, Clinical Screening
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Delaware
Neuropathy, Diabetic, Neuropathy, Painful
Methods of Early Detection and Grading Of Diabetic Peripheral Neuropathy (MEDON)
MEDON aims to examine new methods for early detection and grading of diabetic peripheral neuropathy focusing on both small- and large nerve fibers.
- Trial name
- MEDON (NCT04078516)
- Testing
- Perception Threshold Tracking (PTT), Axon-flair mediated respons, Heart rate variability
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Tennis Elbow Syndrome, Golfer's Elbow
Effects of Peripheral Repetitive Peripheral Magnetic Stimulation on Individuals With Elbow or Wrist Chronic Pain
This pilot, randomized, sham-controlled, single-blind study will evaluate the effectiveness of repetitive peripheral magnetic stimulation (rPMS) in reducing pain in adults with tennis/golfer's elbow or carpal tunnel syndrome.
- Conditions
- Tennis Elbow Syndrome, Golfer's Elbow, Carpal Tunnel Syndrome (CTS)
- Trial name
- rPMS (NCT07544914)
- Testing
- Two days Active rPMS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Diabetic Neuropathies
Trial to Assess the Efficacy and Safety of SPM 927 (200, 400, and 600mg/Day) in Subjects With Painful Distal Diabetic Neuropathy
This phase 3 trial is being conducted at approximately 80 sites in the United States (U.S.) to investigate whether lacosamide (SPM 927) at different doses reduces pain in subjects with diabetic neuropathy.
- Trial name
- NCT00135109
- Testing
- SPM 927
- Where
- United States
- Volunteers
- 654 people
- Sponsor
- UCB Pharma
Complex Regional Pain Syndromes
Ketamine HCl Prolonged Release Oral Tablets for CRPS
The purpose of this study is to evaluate the efficacy of Ketamine HCl Prolonged Release (PR) tablets in participants with pain due to complex regional pain syndrome (CRPS).
- Trial name
- NCT06419985
- Testing
- 80mg/day Ketamine HCl Prolonged Release, 160mg/day Ketamine HCl Prolonged Release
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Southern California
Pain Management
BreEStim in Managing Neuropathic Pain After Spinal Cord Injury (SCI)
The purpose of this study is to compare the effectiveness of innovative intervention of breathing controlled electrical stimulation (BreEStim) and sham BreEStim and Transcutaneous Electrical Nerve Stimulation (TENS) in management…
- Trial name
- NCT07659743
- Testing
- Active BreEStim Treatment, The TENS Treatment
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- The University of Texas Health Science Center, Houston
Neuropathic Pain
Prophylaxis of Neuropathic Pain by mémantine
The aim of this study is to evaluate if memantine administered during 4 weeks beginning 2 weeks before surgery induces a decrease of painful intensity 3 months after surgery, compared to placebo group.
- Trial name
- MEMANTINE (NCT01536314)
- Testing
- Memantine EBIXA®
- Where
- France
- Volunteers
- 43 people
- Sponsor
- University Hospital, Clermont-Ferrand
Carpal Tunnel Syndrome (CTS)
Combined Effects of Neurodynamics With PNF on Pain and ROM in Patients With CTS.
The goal of this clinical trial is to determine the combined effects of neurodynamics with proprioceptive neuromuscular facilitation technique on reducing pain and improving range of motion in patients with carpal tunnel…
- Trial name
- NCT07573878
- Testing
- Neurodynamic and PNF, Baseline Treatment
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
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