Clinical trials: Peripherally Inserted Central Catheter
Shock, Acute Circulatory Failure
Concordance Study of Therapeutic Decision-making in Patients With Shock Based on Hemodynamic Monitoring
Shock is a serious complication corresponding to acute circulatory failure resulting in multiorgan failure and death. In order to improve cellular oxygen utilization, several therapies can be used.
- Conditions
- Shock, Acute Circulatory Failure, Hemodynamic Monitoring
- Trial name
- PICC-ECHO (NCT05613647)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Angers
PICC Line Placement
COMPLI-PICC: Study on Picclines' Complications
This is a prospective monocentric study of PICC Line complications use in 5 medical and one surgical units of Brest Medical University Hospital.
- Trial name
- COMPLI-PICC (NCT03017911)
- Testing
- Piccline
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Brest
Peripheral ICC
Vascular Positioning System G4 Algorithm ECG Data Collection for Model Training Study
The objective of this study is to collect intravascular and extravascular echocardiogram (ECG) data from subjects receiving peripherally inserted central catheters (PICC) while using the Vascular Positioning System G4 and a 12…
- Trial name
- NCT05702515
- Testing
- Digital ECG Data Collection
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Teleflex
Venous Thromboembolism
A Trial to Learn How Well REGN9933 and REGN7508 Work for Preventing Blood Clots, and How Safe They Are, in Adults Who Have a Peripherally Inserted Central Catheter (PICC)
This study is researching 2 different experimental drugs called REGN9933 and REGN7508 (called "study drugs"). The study is focused on adults undergoing a placement of a catheter in the vein, also called a 'PICC line'.
- Trial name
- ROXI-CATH (NCT06299111)
- Testing
- REGN9933, REGN7508
- Where
- 23 sites in United States, Bulgaria and 4 more
- Volunteers
- 195 people
- Sponsor
- Regeneron Pharmaceuticals
Thrombosis
Safety and Efficacy of Tissue Plasminogen Activator (tPA) in Neonates and Infants
The purpose of this study is to determine if alteplase is effective in dissolving a clot in a catheter in a large vein (central venous line or PICC line) or artery in infants less than 6 months of age.
- Trial name
- NCT00265005
- Testing
- alteplase
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Louisville
Vascular Access, PICC Line Placement
PICC Inserted by a Nurse-led Vascular Access Team in Poland
Implantation of PICCs by a trained, dedicated nursing team can be effective and safe, and allows for intravenous therapy that requires medium- to long-term central venous access.
- Trial name
- NIce-PICC (NCT06979128)
- Testing
- PICC placement
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Warsaw
Infant, Premature, Anticoagulants
Heparin Versus no Heparin on Duration of Peripherally Inserted Central Catheter (PICC) Patency in Neonates
Background: Heparin is an anticoagulant commonly used in the neonatal population as a means to prevent catheter related occlusion and malfunction by thrombosis (clot).
- Conditions
- Infant, Premature, Anticoagulants, Thrombosis
- Trial name
- NCT00879957
- Testing
- heparin, No heparin
- Where
- United States
- Sponsor
- The University of Texas Health Science Center at San Antonio
Vascular Access Complication, Skin and Subcutaneous Tissue Disorders
Effectiveness of a Zinc Oxide Adhesive Securement Device in the Fixation of Midline and Peripherally Inserted Central Catheters in Hospitalized Adult Patients
Study in which a zinc oxide fixation device (a product that can help protect the skin) for catheters (polyurethane tubes inserted into a vein) will be tested to reduce catheter-related complications: catheter displacement, skin…
- Conditions
- Vascular Access Complication, Skin and Subcutaneous Tissue Disorders, Phlebitis, Pain
- Trial name
- FIX-ETI (NCT06770374)
- Testing
- Control group: acrylic adhesive sutureless fixation device, Intervention Group: zinc oxide sutureless fixation device, PICC
- Where
- 2 sites in Spain
- Volunteers
- 400 people
- Sponsor
- Hospital Arnau de Vilanova
Catheters, Indwelling, Thrombosis
A Randomized Evaluation of the Effect of Routine Normal Saline Flush Versus Heparinized Saline Solution in Groshong and Groshong PICC Catheters
The Groshong and Groshong PICC catheters are popular venous access devices because they are maintained with only weekly saline flushes.
- Trial name
- NCT00001518
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Hemodynamics, Central Venous Pressure
Reliability of Central Venous Pressure Measurements
The purpose of this study is to compare CVP measurements from CICCs and PICCs. The investigators will also evaluate whether or not the duration of CICC placement affects the differences in CVP measurements between the CICCs and…
- Trial name
- CVP (NCT01116973)
- Testing
- PICC
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of Oklahoma
Venous Thrombosis
Peripherally Inserted Versus Centrally Inserted Central Venous Catheters in the Neurological Intensive Care
The investigators aim to compare the complications between centrally and peripherally inserted central venous catheters in neurological intensive care unit patients.
- Trial name
- PICNIC (NCT01495429)
- Testing
- Central venous catheter
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Michigan
Infection, Cancer
ECG Versus Ultrasound-guided Positioning of the Peripherally Inserted Central Catheter (PICC) Tip
In the prevention of thrombosis related to catheter placement it is important to have a right position of the catheter tip. Therefor we want to assess which technique is the most successful in the placing of a PICC.
- Conditions
- Infection, Cancer, Malnutrition
- Trial name
- NCT02467049
- Testing
- ECG-guided insertion of PICC, ULTRASOUND-guided insertion of PICC
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitair Ziekenhuis Brussel
Catheter-related Bloodstream Infection
Comparison of Early Phase Infections Risk Between Midline and Piccline Caheters: MIDLINE AND PICCLINE CATHETERS
A long-term venous access is frequently required in patient management. Currently, it is ensured by using the long peripheral intravenous catheters (Midline) or peripheral inserted central catheters (PICC line).
- Trial name
- PICCORMID (NCT05264402)
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Deep Vein Thrombosis
Evaluating the Use of Grip Exercises to Decrease Deep Vein Thrombosis in Adult Patients With PICC Lines
Patients who have a peripherally-inserted central catheter (PICC) placed are at a risk of developing a deep vein thrombosis (DVT).
- Trial name
- NCT06370702
- Testing
- Handgrip Exercises
- Where
- 2 sites in United States
- Volunteers
- 2,500 people
- Sponsor
- TriHealth Inc.
Tumor Chemotherapy Patients
Construction and Application of Precise Health Education Model for Patients With PICC Tube
1. In this study, the risk factors leading to catheter-related complications in the daily life behavior habits of patients with PICC catheter were identified, refined and initially established, and the Delphi method (expert…
- Trial name
- NCT05643937
- Testing
- Routine health education, Routine health education + precise health education
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Junyan Zhao
PICC-associated Thrombosis
A Clinical Study to Test the Efficacy and Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a PICC Line
Peripherally Inserted Central Catheters (PICCs) are commonly used in patients with cancer to administer chemotherapy and supportive care medication.
- Trial name
- NCT04281524
- Testing
- CSL312
- Sponsor
- CSL Behring
Chronic Intestinal Failure
A Monocenter Prospective Study to Evaluate the Efficacy of Peripherally Inserted Central Catheter to Tunnelled Central Catheter With Cuff in Home Parenteral Nutrition for Long-term Used.
Home parenteral nutrition (HPN) is the reference treatment for anatomic or fonctionnal chronic intestinal failure. Nutritionnal catheter must follow two rules: low infection rate and be able to preserve the permeability of the…
- Trial name
- PICCNUT (NCT01840033)
- Testing
- group Piccnut, Tunnelled nutritional central catheter
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Central Venous Catheter Thrombosis
The Relationship Between the Lack of AT-Ⅲ, PC, PS Activity and PICC-related Thrombosis
PICC related venous thrombosis (PICC-RVT) is one of the common complications of PICC and the main cause of unplanned extubation.
- Trial name
- NCT04535206
- Testing
- Venous blood collecting and test and ultrasound screening
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Vascular Access Device Complications
Comparing Peripherally Inserted Central Catheters to Long Peripheral Catheters in Pediatrics
Peripherally Inserted Central Catheters (PICCs) are frequently used in hospitalized children who require prolonged vascular access; however, concerns regarding their inappropriate use and contribution to serious complications…
- Trial name
- ComPLET (NCT05346406)
- Testing
- Midline Catheter, Peripherally Inserted Central Catheter
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Medical College of Wisconsin
PICC Placement
Randomized Controlled Trial of Ultrasound-guided Versus Landmark Technique for Peripherally Inserted Central Catheter (PICC) Placement
Peripherally Inserted Central Catheter (PICC) are intravascular devices used on patients undergoing IV therapy. Insertion of these catheters can be achieved either by using the anatomical landmarks for the veins or using…
- Trial name
- NCT02859987
- Testing
- PICC Placement by Landmark Technique, PICC Placement by Ultrasound-guided Technique, Ultrasound Scan
- Volunteers
- 199 people
- Sponsor
- Equipo de Terapia Intravenosa