Clinical trials: Peripherally Inserted Central Catheters
Cancer
Heparin Versus Normal Saline in Peripherally Inserted Central Catheter Lines
The study team will be performing a study comparing the use of Heparin Flushes vs. Normal Saline Flushes in making sure central lines stay open.
- Trial name
- NCT05029596
- Testing
- Normal Saline Group, Heparin Group
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Vascular Access Complication, Skin and Subcutaneous Tissue Disorders
Effectiveness of a Zinc Oxide Adhesive Securement Device in the Fixation of Midline and Peripherally Inserted Central Catheters in Hospitalized Adult Patients
Study in which a zinc oxide fixation device (a product that can help protect the skin) for catheters (polyurethane tubes inserted into a vein) will be tested to reduce catheter-related complications: catheter displacement, skin…
- Conditions
- Vascular Access Complication, Skin and Subcutaneous Tissue Disorders, Phlebitis, Pain
- Trial name
- FIX-ETI (NCT06770374)
- Testing
- Control group: acrylic adhesive sutureless fixation device, Intervention Group: zinc oxide sutureless fixation device, PICC
- Where
- 2 sites in Spain
- Volunteers
- 400 people
- Sponsor
- Hospital Arnau de Vilanova
Catheterization
Peripherally Inserted Central Catheter Placement by IV Team Nurses Using the Sonic Flashlight
The purpose of this study is to test whether peripherally inserted central catheters can be safely placed on patients by intravenous team nurses at the bedside.
- Trial name
- NCT00226226
- Testing
- Peripherally Inserted Central Catheter Placement
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- University of Pittsburgh
Adult Patients With Mid-term or Long-term Venous Access
Evaluation of Tissue Glue on PICC and Midline Catheters Insertion Sites
The study will evaluate a new type of cyanoacrylate tissue glue Secure PortIV on the insertion site of the PICC (Peripherally inserted central catheter) or Midline catheters.
- Trial name
- NCT04900740
- Testing
- Catheter fixation with surgical stitch, Catheter fixation with glue (cyanoacrylate tissue glue Secure PortIV)
- Where
- Czechia
- Volunteers
- 250 people
- Sponsor
- University Hospital Ostrava
Peripherally Inserted Central Catheters, CVC
Suitability of PICC for Transpulmonary Thermodilution Compared to CICC
Peripherally inserted central catheters (PICCs) are increasingly used in intensive care unit (ICU) as an alternative to centrally inserted central catheters (CICCs) for intravenous infusion.
- Conditions
- Peripherally Inserted Central Catheters, CVC, Transpulmonary Thermodilution, Hemodynamic Monitoring
- Trial name
- NCT03834675
- Testing
- transpulmonary thermodilution
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Patients Cannulated With Both PICC and CICC., The Rapidly Fluctuating Hemodynamics During LT.
Comparison of Central Venous Pressures (CVPs) Measured From Peripherally Inserted Central Catheters (PICC) and CICC in Liver Transplantation Recipients
Background: Central venous pressure (CVP) monitoring from the peripherally inserted central venous catheter (PICC) has not often been used because of the higher inherent resistance of the PICC due to its longer length and…
- Trial name
- PICC (NCT00988871)
- Testing
- PICC, CICC
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- National Cancer Center, Korea
Catheter-Related Infections, Catheter Related Complication
Comparison of Two Peripheral Inserted Intravenous Catheters
Central venous catheters are routinely used, however, with a complication rate exceeding 15%. Therefore, other types of venous catheters have been introduced such as a midline catheter.
- Trial name
- NCT04140916
- Testing
- Midline catheter, PICC-line catheter
- Where
- Denmark
- Volunteers
- 304 people
- Sponsor
- Aalborg University Hospital
Peripherally Inserted Central Catheters
Magnetic Tracking and ECG-Guided Tip Confirmation System for PICCs
This prospective study enrolled cancer patients who underwent peripherally inserted central catheter (PICC) placement at a tertiary care oncology hospital in Guangzhou between January 1st and May 30th, 2026.
- Trial name
- NCT07369427
- Testing
- Sherlock 3CG Tip Confirmation System
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Sun Yat-sen University
Adult Patients With Peripherally Inserted Central Catheters
Observational Study of Complications Related to Use of Peripherally Inserted Central Catheters
The purpose of this study is to determine the rate and timing of interventions and complications related to the use of peripherally inserted central venous catheters in adult patients.
- Trial name
- PRISM-1 (NCT01578993)
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Teleflex
Cancer Patients
Effects of Different PICC Catheterization Methods: A Multicenter Randomized Controlled Trial
This study aims to compare the clinical effectiveness of three PICC (Peripherally Inserted Central Catheter) insertion methods: conventional non-tunneled PICC, one-needle tunneled PICC, and two-needle tunneled PICC.
- Trial name
- NCT07791719
- Testing
- Conventional Non-Tunneled PICC catheterization, One-Needle Tunneled PICC catheterization, Two-Needle Tunneled PICC catheterization
- Where
- China
- Volunteers
- 801 people
- Sponsor
- Sun Yat-sen University
Patients With Any Condition Who Need a PICC for IV Therapy
SecurAcath Versus Statlock for PICC Securement
Peripherally inserted central catheters (PICCs ) are used for the administration of intravenous fluids and for blood sampling. PICCs may remain in place for weeks to months and are safeguarded from migration or accidental…
- Trial name
- SecurAstaP (NCT02311127)
- Testing
- SecurAcath, StatLock
- Where
- Belgium
- Volunteers
- 105 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Infection Associated With Catheter, Bacteremia
Safety and Efficacy Study of Ethanol Locking to Prevent Central Line Infection in Premature Neonates
Appropriate delivery of adequate nutrition and medications in premature infants often requires central venous access in the form of a special IV called a PICC (peripherally inserted central catheter).
- Conditions
- Infection Associated With Catheter, Bacteremia, Sepsis
- Trial name
- NCT01365312
- Testing
- Ethanol lock, Heparinized saline
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- East Carolina University
Insertion of Peripherally Inserted Central Catheter
AR Ruler to Improve Safety and Clinical Workflow During PICC Placement
The purpose of this study is to assess the utility of an augmented reality virtual ruler during placement of peripherally inserted central catheters.
- Trial name
- NCT05399875
- Testing
- Augmented reality virtual ruler
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Infection, Cancer
ECG Versus Ultrasound-guided Positioning of the Peripherally Inserted Central Catheter (PICC) Tip
In the prevention of thrombosis related to catheter placement it is important to have a right position of the catheter tip. Therefor we want to assess which technique is the most successful in the placing of a PICC.
- Conditions
- Infection, Cancer, Malnutrition
- Trial name
- NCT02467049
- Testing
- ECG-guided insertion of PICC, ULTRASOUND-guided insertion of PICC
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitair Ziekenhuis Brussel
CLABSI - Central Line Associated Bloodstream Infection
Risk Factors for PICC-Related Infection in 994 High-Risk Patients: The Role of Hb Levels and Sampling Frequency
This retrospective cohort study aims to evaluate the incidence and clinical predictors of Central Line-Associated Bloodstream Infections (CLABSI) in patients receiving Peripherally Inserted Central Catheters (PICCs) via the…
- Trial name
- NCT07674992
- Testing
- Hemoglobin level
- Where
- Thailand
- Volunteers
- 1,239 people
- Sponsor
- Mahidol University
Solid Tumor
PICC-ports Versus Chest - Ports for Long Term Chemotherapy Deliverance in Oncology Patients
Central venous access devices are extensively used in oncology patients. The current standard is represented by devices inserted by direct ultrasound guided cannulation of deep veins of supra/infraclavicular area with a reservoir…
- Trial name
- PICCHEST (NCT06541301)
- Testing
- PICC-port, Chest-port
- Where
- 3 sites in Italy
- Volunteers
- 852 people
- Sponsor
- European Institute of Oncology
Vascular Access Complication, Vascular Access Related Infection
Arrow Chloragard Peripherally-Inserted Central Catheters (PICC) Study
A prospective study evaluating the timing, incidence and relationship of commonly occurring complications related to the use of peripherally-inserted central catheters.
- Trial name
- NCT03019302
- Testing
- Arrow PICC with Chloragard Technology
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Teleflex
Catheter Related Infections
Safety and Bacteraemia Between Peripherally Inserted and Central Inserted Catheters.
Clinical, prospective, single-center, national trial. open and randomized at 1: 1 to compare the rate of bacteremia associated between non-tunneled Central venous catheter and peripheral inserted central catheter.
- Trial name
- PYCBAC (NCT02538159)
- Testing
- CVC, PICC
- Where
- Spain
- Volunteers
- 247 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Infusions, Intravenous, Administration, Intravenous
Digital Transformation of Continuity of Care for Peripherally Inserted Central Catheters: SpadCare Experience
The study focuses on patients who require outpatient infusion of therapy ("Infusions, Intravenous"[Mesh]) "Administration, Intravenous"[Mesh] ("Home Infusion Therapy"[Mesh]) "Parenteral Nutrition, Home"[Mesh] via a peripherally…
- Conditions
- Infusions, Intravenous, Administration, Intravenous, Home Infusion Therapy, Parenteral Nutrition, Home
- Trial name
- SpadCare (NCT06905119)
- Testing
- Digital Transformation of Continuity of Care for Peripherally Inserted Central Catheters
- Where
- Spain
- Volunteers
- 201 people
- Sponsor
- Fundacion Miguel Servet
Peripherally Inserted Central Catheters
Point of Care Ultrasound for PICC Line Monitoring Study
A prospective comparative study evaluating chest x-ray determination of PICC line tip location and POC ultrasound PICC line tip location.
- Trial name
- PUP (NCT03954977)
- Testing
- PICC line ultrasound
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital