Clinical trials: Peritoneal Adhesions
Peritoneal Adhesions
Differences in Peritoneal Stem Cells in Women With and Without Adhesions After Gynaecological Surgery
Our study aims to characterise a possible pluripotent cell population in the abdomen responsible for peritoneal adhesions. We therefore want to take samples from women undergoing planned laparoscopic surgery with and without…
- Trial name
- NCT02847676
- Testing
- Tissue sample donation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pius-Hospital Oldenburg
Adhesive Small Bowel Obstruction, Postoperative Abdominal Adhesions
Adhesion Prevention in ASBO Surgery Using 4DryField® PH
Post-surgical adhesions occur in up to 90% of abdominal surgeries, often leading to complications like adhesive small bowel obstruction (ASBO) and chronic pain.
- Conditions
- Adhesive Small Bowel Obstruction, Postoperative Abdominal Adhesions, Bowel Obstruction, Abdominal Surgery Complications
- Trial name
- ADHERE (NCT07078981)
- Volunteers
- 189 people
- Sponsor
- Alessio Giordano
Neoplasm, Stomach, Metastases, Neoplasm
Intraperitoneal Infusion of EpCAM CAR-T Cell in Advanced Gastric Cancer With Peritoneal Metastasis (WCH-GC-CART)
To investigate the safety and efficacy of intraperitoneal infusion of EpCAM CAR-T cell in advanced gastric cancer with peritoneal metastasis by a prospective nonrandomized controlled trial.
- Conditions
- Neoplasm, Stomach, Metastases, Neoplasm, Neoplasm Seeding
- Trial name
- NCT03563326
- Testing
- CAR-T cells targeting EpCAM, Chemotherapy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Jian-Kun Hu
Colon Cancer, Rectal Cancer
Pilot Study Evaluating the Efficacy of AlloMEM After Loop Ileostomy
The objective of this study is to investigate whether the use of Human Peritoneal Membrane (HPM) in a temporary loop ileostomy is beneficial to patients.
- Trial name
- AlloMem (NCT01113736)
- Testing
- AlloMEM™
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Adhesive Peritoneal Band
Intra-Abdominal Instillation Of Fresh Frozen Plasma Versus Corticosteroids In Prevention Of Recurrent Attacks Of Adhesive Intestinal Obstruction: A 2 Years' Experience Clinical Study
Adhesive Intestinal obstruction is an inevitable complication of abdominal surgery with significant morbidity associated with poor quality of life and predispose to repeated hospitalization.
- Trial name
- NCT06859307
- Testing
- intra-abdominal instillation of corticosteroids, intra-abdominal instillation of fresh frozen plasma
- Where
- 2 sites in Egypt
- Volunteers
- 176 people
- Sponsor
- Zagazig University
Endometriosis of the Cul-de-sac, Chocolate Cyst of Ovary
Peritoneal Cavity Conditioning Decreases Pain, Inflammation and Adhesions
Full conditioning of the peritoneal cavity during laparoscopic surgery will decrease post-operative pain, inflammation and adhesion formation.
- Conditions
- Endometriosis of the Cul-de-sac, Chocolate Cyst of Ovary, Fibroid/Myoma (Uterus/Cervix)
- Trial name
- NCT01344486
- Testing
- full conditioning, standard pneumoperitoneum
- Where
- Belgium
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Cesarean Section, Adhesions
Closure of Peritoneum at Cesarean Section and Postoperative Adhesion
Objective: To determine the effect of non-closure of the visceral and parietal peritoneum during Cesarean section on the formation of adhesions.
- Trial name
- cs adhesions (NCT01183000)
- Testing
- Closure of the peritoneum at cs
- Where
- 2 sites in Israel
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- Barzilai Medical Center
Pneumoperitoneum
CO2 Absorption During Laparoscopy
CO2 absorption from the pneumoperitoneum increases over time during laparoscopic procedures. Adding 4% of oxygen to the carbon dioxide was shown in rabbits to decrease CO2 resorbtion through prevention of mesothelial hypoxia.
- Trial name
- NCT01340989
- Testing
- alteration of the insufflation gas, full conditioning, standard pneumoperitoneum
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
End-Stage Kidney Disease (ESKD), Hemodialysis
Cardiovascular and Bone Mineral Markers in Dialysis Patients and Healthy Controls
This observational study will compare cardiovascular status, bone mineral metabolism, systemic inflammation, body composition, functional status, quality of life, pruritus, and pain among patients receiving different renal…
- Conditions
- End-Stage Kidney Disease (ESKD), Hemodialysis, Peritoneal Dialysis (PD)
- Trial name
- NCT07686978
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gazi University
Peritoneal Adhesion
Intraperitoneal Chemotherapy Alone or in Combination With Bevacizumab for Ovarian Cancer With Peritoneal Adhesion
Background: Malignant peritoneal adhesion is a common complication and prognostic factor of ovarian cancer and other primary abdominal tumors.
- Trial name
- NCT03095001
- Testing
- Bevacizumab, Carboplatin, paclitaxel
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Chinese PLA General Hospital
Peritoneal Surface Malignancy, Postoperative Adhesion
SurgiPerito Trial: High-Purity Type-I Collagen for Peritoneal Reconstruction After Cytoreductive Surgery
This dual-centre, randomized controlled trial evaluates the safety and efficacy of high-purity Type-I collagen-based biomaterial, as a peritoneal substitute following peritonectomy in patients undergoing cytoreductive surgery…
- Conditions
- Peritoneal Surface Malignancy, Postoperative Adhesion, Bowel Obstruction, Wound Complications
- Trial name
- NCT07241091
- Testing
- High-Purity Type-I Collagen Scaffold, Standard Peritonectomy Closure
- Where
- 2 sites in India
- Volunteers
- 60 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Myomas, Ovary Cysts
The Efficacy and Safety Study of a New Cross-linked Hyaluronan Hydrogel in the Reduction of Postsurgical Peritoneal Adhesions
The purpose of this study was to determine whether the new crosslinked hyaluronan hydrogel was safe to use, and was effective for the prevention/reduction of adhesion formation following gynecological surgery
- Conditions
- Myomas, Ovary Cysts, Endometriotic Cysts, Adhesions
- Trial name
- BAP (NCT02166554)
- Testing
- Saline, Cross-linked Hyaluronan Hydrogel
- Where
- 7 sites in China
- Volunteers
- 216 people
- Sponsor
- BioRegen Biomedical (Changzhou) Co., Ltd
Endometriosis
Study to Compare Peritoneal Ablation by Excision Only and Excision With the Use of an Adhesion Barrier
Endometriosis is a common disease of women in the reproductive age and is an important cause for female infertility. Endometriosis is often associated with the development of adhesions which further compromises the fertility of…
- Trial name
- NCT02165917
- Testing
- Excision plus hyaluronic acid gel, Excision only
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Pius-Hospital Oldenburg
Kidney Failure, Chronic, Disorders Associated With Peritoneal Dialysis
Effect of Glucose Degradation Products (GDP) on Endothelial Dysfunction
The purpose of this study is to evaluate the effects of neutral pH and low glucose degradation product (GDP)-containing peritoneal dialysis fluid (PDF) on systemic inflammation and endothelial dysfunction markers in incident PD…
- Trial name
- NCT01315314
- Testing
- Balance, Fresenius Medical Care, Germany
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Kyungpook National University Hospital
Postoperative Adhesion, Peritoneal Adhesion, Nos
Efficacy of Sprayable PEG Barrier in Gynecologic Laparoscopy
The purpose of the study is to investigate whether sprayable PEG barrier is effective in reducing adhesions in laparoscopic gynecologic surgery.
- Trial name
- NCT01187680
- Testing
- Spraygel, Control
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- Radboud University Medical Center