Clinical trials: Peritoneal Dialysis Patients
Chronic Kidney Diseases, Peritoneal Dialysis
Effects of Curcumin Supplementation in Patients With Chronic Kidney Disease on Peritoneal Dialysis
The objective of this study is to assess whether supplementation with curcumin could modulate the intestinal microbiota, reducing levels of inflammatory markers of oxidative stress, uremic toxins and inflammasome, in patients…
- Conditions
- Chronic Kidney Diseases, Peritoneal Dialysis, Hemodialysis
- Trial name
- NCT04413266
- Testing
- Curcumin supplementation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal Fluminense
End-Stage Renal Disease
Assessment of Telehome Monitoring in Patients on Peritoneal Dialysis: A Multicentre Randomized Controlled Trial
Compared to hemodialysis, patients on peritoneal dialysis live longer and healthier, have a higher quality of life and cost approximately $40,000 less to the healthcare system per patient per year.
- Trial name
- CONNECT (NCT02670512)
- Testing
- Telehome Monitoring
- Where
- 11 sites in Canada
- Volunteers
- 467 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
End Stage Renal Failure on Dialysis
Effect of Prebiotics and/or Probiotics on Uremic Toxins and Inflammation Markers in Peritoneal Dialysis Patients
End-stage renal disease (ESRD) is a world public health problem, with high morbidity and mortality. Cardiovascular disease is the main cause of mortality in ESRD; uremic toxin retention and inflammation are considered…
- Trial name
- NCT03770611
- Testing
- Probiotic, Prebiotic, Symbiotic
- Where
- Mexico
- Volunteers
- 112 people
- Sponsor
- Unidad de Investigacion Medica en Enfermedades Renales
Disorders Associated With Peritoneal Dialysis
Effects of Aceis on Peritoneal Protein Loss and Solute Transport in pd Patients
The objective of this study was to examine the effects of angiotensin converting enzyme inhibitors on peritoneal membrane transport, peritoneal protein loss, and proteinuria in peritoneal dialysis patients.
- Trial name
- NCT01575652
- Testing
- Group using angiotensin converting enzyme inhibitor, Group not using angiotensin converting enzyme inhibitor
- Volunteers
- 43 people
- Sponsor
- Turkish Nephrology Association
Secondary Hyperparathyroidism
Study of KHK7580 for Secondary Hyperparathyroidism in Patients Receiving Peritoneal Dialysis
This study is designed to evaluate safety, pharmacokinetics and pharmacodynamics after single administration of KHK7580 for secondary hyperparathyroidism in patients receiving peritoneal dialysis.
- Trial name
- NCT02143271
- Testing
- KHK7580
- Where
- Japan
- Volunteers
- 13 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Anemia, Peritoneal Dialysis
Oral Vitamin C for Correction of Anemia in Patients Receiving Peritoneal Dialysis
People with kidney failure are at risk for the development of anemia. Anemia is a decrease in the production of hemoglobin, a substance that carries oxygen in the blood.
- Trial name
- NCT00920413
- Testing
- Vitamin C
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Unity Health Toronto
Hypertension,Nephropathy
Nighttime Losartan in Continous Ambulatory Peritoneal Dialysis (NVCAPD)
Hypertension is one of the most important independent risk factors for the prognosis of continous ambulatory peritoneal dialysis patients. The incident rate is high and the control rate is low.
- Trial name
- NCT03692013
- Testing
- Losartan
- Volunteers
- 68 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Vitamin D Deficiency, Vascular Calcification
Effects of Cholecalciferol on Osteoprotegerin Levels in Patients on Peritoneal Dialysis
Aim: To investigate whether cholecalciferol (4800 U/daily) or placebo for 16 weeks reduces proteins levels associated with vascular calcification (osteoprotegerin, osteopontin, osteocalcin) in patients treated with peritoneal…
- Conditions
- Vitamin D Deficiency, Vascular Calcification, Renal Insufficiency, End Stage Renal Failure on Dialysis
- Trial name
- NCT02598635
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 58 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
End Stage Renal Disease (ESRD)
Bayston Multicenter Antimicrobial PD Catheter Safety Study
The study was designed to establish the safety of the Bayston Antimicrobial PD catheter that is impregnated with a "cocktail" of three well known anti-microbials
- Trial name
- Bayston (NCT02274896)
- Testing
- PD Catheter group
- Where
- 5 sites in Belgium, Netherlands and 1 more
- Sponsor
- Medical Components, Inc dba MedComp
Quality of Life, Mental Health Wellness 1
QOL and Mental Health Using APD With Remote Monitoring System
Although peritoneal dialysis (PD) is a representative renal replacement therapy along with hemodialysis, number of PD patients decreases every year.
- Trial name
- NCT07012499
- Testing
- Automated peritoneal dialysis with Sharesource device, APD without sharesource
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Wonju Severance Christian Hospital
Peritoneal Dialysis Complication
EMT in Peritoneal Dialysis Patients
Approximately 10-11% of end stage kidney disease patients worldwide utilize peritoneal dialysis (PD) as their method of renal replacement therapy.
- Trial name
- NCT03458819
- Testing
- Isolation of peritoneal mesothelial cells
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Colorado, Denver
End Stage Renal Disease, Peritoneal Dialysis-associated Peritonitis
A Prospective Clinical Study to Assess the Clinical Utility of Turbidity in Patients Using In-Home Peritoneal Dialysis
This study aims to determine if the CloudCath device can detect infections related to peritoneal dialysis (peritonitis) as fast or faster than the current standard methods used by patients and doctors to detect such infections.
- Conditions
- End Stage Renal Disease, Peritoneal Dialysis-associated Peritonitis, Peritonitis
- Trial name
- ACT (NCT05285436)
- Testing
- CloudCath System
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- CloudCath
Iron Deficiency Anemia
2 Doses of Ferrlecit Versus Oral Iron to Treat Iron-deficiency Anemia in Peritoneal Dialysis Patients.
This is a phase 3 clinical investigation. Patients who meet the eligibility criteria and provide signed informed consent will be randomized to receive one of two levels of Ferrlecit or oral iron in a 1:1:1 ratio.
- Trial name
- NCT00223977
- Testing
- Sodium Ferric Gluconate Complex, Oral Iron
- Where
- 43 sites in United States, Bulgaria and 6 more
- Volunteers
- 146 people
- Sponsor
- Watson Pharmaceuticals
Chronic Kidney Disease, Peritoneal Dialysis
Efficacy and Safety of a 7.5% Icodextrin Peritoneal Dialysis Solution in Once-Daily Long Dwell Exchange
The purpose of this study is to evaluate the efficacy and safety of a 7.5% Icodextrin peritoneal dialysis solution for once-daily long dwell exchange in patients undergoing Continuous Ambulatory Peritoneal Dialysis (CAPD) in…
- Trial name
- NCT00725517
- Testing
- Icodextrin
- Volunteers
- 2 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Ultra Filtration Failure
Evaluation of Autologous Adipose Derived Mesenchymal Stromal Cells (AD-MSC) Transplantation in Ultra Filtration Failure (UFF)
Peritoneal fibrosis may be occurred as a serious complication of peritoneal dialysis. It's the main factor of UFF that could lead to the Encapsulating Peritoneal Sclerosis (EPS).
- Trial name
- NCT02801890
- Testing
- Intravenous injection
- Where
- Iran
- Volunteers
- 10 people
- Sponsor
- Royan Institute
End Stage Renal Disease
Fluid Overload in Peritoneal Dialysis
The objective of this study is to determine the effectiveness of treating peritoneal dialysis (PD) patients with fluid overload by a structured nurse-lead intervention protocol.
- Trial name
- NCT02557347
- Testing
- Aggressive fluid management
- Where
- Hong Kong
- Volunteers
- 102 people
- Sponsor
- Chinese University of Hong Kong
Adverse Event, Peritoneal Dialysis
Efficacy and Safety of Nalfurafine Hydrochloride ODT for Moderate-to-Severe Pruritus in Patients on Peritoneal Dialysis
Moderate to severe pruritus significantly impairs the quality of life in peritoneal dialysis patients, and effective treatment options remain limited.
- Conditions
- Adverse Event, Peritoneal Dialysis, Moderate-to-severe Pruritus, Chronic Kidney Disease-associated Itch
- Trial name
- KARE-PD (NCT07098351)
- Testing
- Remitch
- Where
- China
- Volunteers
- 93 people
- Sponsor
- Guangdong Provincial People's Hospital
Endstage Renal Disease
Risk Assessment by Cardiovascular Biomarkers in Chronic Dialysis Patients
Patients undergoing chronic dialysis are at a substantially increased risk of cardiac death. The reasons for this excess cardiovascular mortality are only partly understood.
- Trial name
- RACE (NCT02207153)
- Where
- Switzerland
- Volunteers
- 217 people
- Sponsor
- University Hospital, Basel, Switzerland
Kidney Failure, Chronic
Evaluation of the Integrated Home Dialysis Model
The purpose of this study is to evaluate which home dialysis modality pattern (home hemodialysis [HHD], peritoneal dialysis [PD] or a combination of both, e.g.
- Trial name
- NCT02278159
- Testing
- Peritoneal dialysis, Home hemodialysis
- Volunteers
- 11,600 people
- Sponsor
- Princess Alexandra Hospital, Brisbane, Australia
End Stage Renal Disease on Dialysis, Hemodialysis
Interdialytic Peritoneal UltraFiltration in HemoDialysis Patients
Sodium accumulates in the tissues of patients with kidney disease and impairs survival. Three-times weekly, standard hemodialysis alone cannot remove excess sodium efficiently.
- Conditions
- End Stage Renal Disease on Dialysis, Hemodialysis, Peritoneal Dialysis, Nonosmotic Sodium Storage
- Trial name
- IPUF-HD (NCT04603014)
- Testing
- Interdialytic peritoneal ultrafiltration with 10% dextrose solution
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's