Clinical trials: Peritonitis
Spontaneous Bacterial Peritonitis
Nitazoxanide in Prevention of Secondary Spontaneous Peritonitis
the study is to evaluate the possible efficacy and safety of nitazoxanide as an adjuvant therapy in the secondary prevention of SBP in patient with cirrhosis.
- Trial name
- NCT04746937
- Testing
- Nitazoxanide, Norfloxacin
- Volunteers
- 60 people
- Sponsor
- Tanta University
Postoperative Peritonitis
Impact of Rapid Molecular Diagnostic Method on Antibiotics Exposure Duration in ICU Patients with Postoperative Peritonitis
Hospitals, and more specifically Intensive Care Units (ICU), face the challenging issue of emergence and rapid spread of multi-drug resistant bacteria (MDR). In some cases, the therapeutic choice is extremely limited.
- Trial name
- DIRECTABDO (NCT04925388)
- Testing
- rapid molecular diagnosis, conventional method analysis
- Where
- 7 sites in France
- Volunteers
- 16 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Abdominal Trauma, Abdominal Injury
A Non-Traumatic Binder for Temporary Abdominal Wall Closure
At the end of most abdominal operations, the fascial layer is closed by stitching edges of the wound together. However, because of logistic and/or technical reasons or the patient's critical condition, the surgeon is forced to…
- Conditions
- Abdominal Trauma, Abdominal Injury, Abdominal Infection, Abdominal Sepsis
- Trial name
- ABRO (NCT03815370)
- Testing
- Experimental: ABRO™ Binder Arm
- Where
- 4 sites in Canada
- Volunteers
- 140 people
- Sponsor
- Unity Health Toronto
CAPD-related Peritonitis
Clinical Pharmacokinetic Study of Ceftazidime and Cefazolin
Peritoneal dialysis-related peritonitis is a common complication of peritoneal dialysis, which is the main cause of transfer from peritoneal dialysis to hemodialysis.
- Trial name
- NCT04367974
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Spontaneous Bacterial Peritonitis
Predicting and Monitoring Spontaneous Bacterial Peritonitis in Cirrhotic Patients Using the Mansoura Scoring System
The aim of this prospective study was to examine predictors of SBP in order to develop a noninvasive method to identify or exclude an episode of SBP, for starting early treatment with antibiotics, so decrease morbidity and…
- Trial name
- MaSS/SBP (NCT07024355)
- Volunteers
- 250 people
- Sponsor
- Assiut University
Spontaneous Bacterial Peritonitis, Cirrhosis
Randomized Comparison of Two Albumin Administration Schedules for Spontaneous Bacterial Peritonitis (SBP)
Spontaneous bacterial peritonitis (SBP) is a common and frequently fatal complication of end-stage liver disease with a mortality of up to 10%, primarily due to the development of kidney failure.
- Trial name
- NCT00761098
- Testing
- Standard Care, Experimental
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Weill Medical College of Cornell University
Sepsis, Hypovolemia
The Impact of Focused Transthoracic Echocardiography in Urgent Abdominal Surgery for Septic Patients
The aim of the study is to identify the diagnostic value of the focused assessed echocardiography in septic patients undergoing urgent abdominal surgery due to peritonitis.
- Conditions
- Sepsis, Hypovolemia, Peritonitis
- Trial name
- ECHOCARD (NCT02846948)
- Testing
- Focused assessed echocardiography
- Where
- Lithuania
- Volunteers
- 131 people
- Sponsor
- Lithuanian University of Health Sciences
End Stage Renal Disease, Peritoneal Dialysis
Chlorhexidine Gluconate Versus Mupirocin Ointment in the Prevention of Peritoneal Dialysis-Related Infection
This pilot study aims to evaluate effectiveness, safety, and cost-utility of chlorhexidine gluconate (CHG)-soaked cloths compares to mupirocin ointment and exit site usual care (normal saline) with aseptic technique in prevention…
- Trial name
- COSMO-PD (NCT02547103)
- Testing
- Chlorhexidine gluconate-soaked cloths, Normal saline, mupirocin ointment
- Where
- Thailand
- Volunteers
- 354 people
- Sponsor
- Chiang Mai University
Proton Pump Inhibitor Adverse Reaction, Liver Cirrhosis
Proton Pump Inhibitors in Cirrhotic Patients
Proton pump inhibitors (PPIs) inappropriate use, in patients with cirrhosis, presents a significant clinical challenge. This study evaluates overprescription and misuse of PPIs in cirrhotic patients.
- Trial name
- NCT06384443
- Where
- Egypt
- Volunteers
- 1,000 people
- Sponsor
- National Liver Institute, Egypt
Abdominal Sepsis, Abdominal Infection
Closed or Open Abdomen for the Management of Abdominal Sepsis
This is a prospective randomized clinical study. The study will comprise the randomized decision to either A) primarily close the fascia after laparotomy for intra-abdominal infection (CLOSED); or B) leave the fascia open after…
- Trial name
- NCT03163095
- Testing
- Open Abdomen Management with ANPPT dressing, Closed Abdomen Management
- Where
- Canada
- Volunteers
- 550 people
- Sponsor
- University of Calgary
Peritonitis
Single Versus Combined Antibiotic Therapy for Bacterial Peritonitis in CAPD Patients
To compare the efficacy of single versus combined antibiotic therapy for bacterial peritonitis in CAPD patients.
- Trial name
- NCT01785641
- Testing
- ceftazidime+ciprofloxacin, ceftazidime monotherapy, cefazolin+gentamicin
- Where
- Thailand
- Volunteers
- 300 people
- Sponsor
- Chulalongkorn University
Cirrhosis
Predictors of Spontaneous Bacterial Peritonitis Among Patients with Cirrhosis
Prevalence of spontaneous bacterial peritonitis (SBP) varies from approximately 4% among asymptomatic patients to 30% among those hospitalized [1, 2].Previous studies explored the role of several biomarkers, such as tumor…
- Trial name
- NCT06884306
- Volunteers
- 200 people
- Sponsor
- Assiut University
Peritoneal Dialysis-associated Peritonitis
A Prospective Clinical Study of the CloudCath System During In-home Peritoneal Dialysis
This study aims to determine if the CloudCath device can detect infections related to peritoneal dialysis (peritonitis) as fast or faster than the current standard methods used by patients and doctors to detect such infections.
- Trial name
- CATCH (NCT04515498)
- Testing
- CloudCath Monitoring System
- Where
- United States
- Volunteers
- 243 people
- Sponsor
- CloudCath
Peritonitis Infectious, Gastrointestinal Perforation, Surgical Infection, Postoperative Complications
Predictors of Morbidity in Perforation Peritonitis: A Prospective Observational Study From a Tertiary Care Centre in North India
This is a prospective observational cohort study conducted at a tertiary care hospital in North India. The study aims to evaluate clinical and biochemical predictors of postoperative morbidity in patients undergoing emergency…
- Trial name
- PERIMOPP (NCT07047911)
- Testing
- Observational only - surgical management not assigned by study
- Volunteers
- 50 people
- Sponsor
- Government Medical College, Patiala
Peritoneal Dialysis Associated Peritonitis
Bacteria Endotoxin in Peritoneal Dialysis Effluent as a Predictor of Relapsing, Recurrent, and Repeat Peritonitis
Peritoneal dialysis (PD) is the first-line treatment of end stage renal disease (ESRD) in Hong Kong. Despite the advances in antibiotic therapy and connecting system, recurrent peritonitis remains the major cause of peritoneal…
- Trial name
- NCT01817309
- Testing
- endotoxin assay in peritoneal dialysis effluent
- Where
- Hong Kong
- Volunteers
- 325 people
- Sponsor
- Chinese University of Hong Kong
Acute Abdomen, Bowel Obstruction
The Best Care for Abdominal Emergencies Study
This is a single-centre retrospective cohort study utilising electronic hospital records. The aim of this study is to improve care for all patients with an intestinal emergency, irrespective of whether they have surgery or not.
- Conditions
- Acute Abdomen, Bowel Obstruction, Bowel; Ischemic, Acute, Bowel Perforated
- Trial name
- BCAE (NCT04577339)
- Testing
- Laparotomy or laparoscopy
- Where
- United Kingdom
- Volunteers
- 2,500 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Peritonitis, Surgical Site Infection
NPWT vs Primary Closure in SSI Prevention for Emergency Laparotomies for Peritonitis
The study aims to evaluate the efficacy of negative pressure wound therapy (NPWT) compared with primary closure (PC) in surgical site infection (SSI) prevention for laparotomy for peritonitis.
- Conditions
- Peritonitis, Surgical Site Infection, Infections, Wound Infection
- Trial name
- PRISTINE (NCT05684198)
- Testing
- subcutaneous NPWT
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Gdansk
Ascites, Peritoneal Carcinomatosis
Comparison of "Roll-over' Technique With Standard Abdominal Paracentesis in Suspected Peritoneal Carcinomatosis
The study will be a randomized trial that will compare two techniques of abdominal paracentesis in patients with suspected peritoneal carcinomatosis.
- Conditions
- Ascites, Peritoneal Carcinomatosis, Peritoneum Neoplasm, Tuberculous Peritonitis
- Trial name
- ROLLON (NCT04232384)
- Testing
- Standard Paracentesis, Roll Over Paracentesis
- Where
- India
- Volunteers
- 71 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Cirrhosis, Spontaneous Bacterial Peritonitis
Doxycycline for the Prevention of Spontaneous Bacterial Peritonitis
The utilization of doxycycline for SBP prophylaxis is a novel practice at MDMC. Therefore, an assessment of safety and efficacy is needed in order to generalize this practice.
- Trial name
- NCT04153604
- Testing
- doxycycline
- Where
- United States
- Volunteers
- 841 people
- Sponsor
- Methodist Health System
Cirrhotic Patients With Spontaneous Bacterial Peritonitis
Platelets to Lymphocytes Ratio and Monocytes to Lymphocytes Ratio as Predictors of Response to Treatment in Cirrhotic Patients With Spontaneous Bacterial Peritonitis.
Spontaneous bacterial peritonitis (SBP) is a serious complication of ascites that can lead to death and can be described as an acute infection of ascites without any certain source of infection SBP is considered the most common…
- Trial name
- NCT05850858
- Testing
- ascetic fluid study
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Sohag University