Clinical trials: Personality Change
Borderline Personality Disorder
Neuropsychiatric Mechanisms of Change in Mentalization Based Treatment of Borderline Personality Disorder (MENTAB)
Purpose: Borderline personality disorder (BPD) is a complex psychiatric disease of uncertain aetiology and pathogenesis. A key mechanism of disease susceptibility and treatment response could be epigenetic changes in DNA…
- Trial name
- MENTAB (NCT01720953)
- Testing
- Mentalization Based Therapy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rune Andersen
Anger, Stress
Hostile Bias Modification Training (HBMT) Study
The primary objective of the present protocol is to evaluate the effectiveness of real HBMT versus placebo on reducing HAB and aggression. The secondary objectives of the present protocol are: 1.
- Conditions
- Anger, Stress, Aggression
- Trial name
- NCT04997356
- Testing
- Hostile Bias Modification Training, Other training
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)
GERM CELLS
Motivations and Psychological Aspects of Gamete Donation
The objective of this project is to describe the motivations, the representation of donation and sterility, to evaluate the psychological aspects of the new male and female candidates to gamete donation and then to compare the…
- Trial name
- DONDON2 (NCT06014151)
- Testing
- questionnaires
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Personality
Personality and Drug Use (PDU)
The study aims to assess whether the use of drugs relates to personality ratings. Specifically, we plan to investigate if people with different histories of substance use differentiate on personality assessments (current and…
- Trial name
- PDU (NCT05180149)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Quantified Citizen Technologies Inc.
Borderline Personality Disorder
Biomarkers of Change in BPD After Metacognitive Interpersonal Therapy-standard Approach
The present randomised clinical trial aims to assess the clinical and neurobiological changes following Metacognitive Interpersonal Therapy -standard approach (MIT-SA) compared with Clinical Structured Treatment (CST) derived…
- Trial name
- CLIMAMITHE (NCT02370316)
- Testing
- Metacognitive Interpersonal Therapy (MIT-SA), Clinical Structured Treatment
- Where
- Italy
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Alzheimer's Disease, Parkinson's Disease
Social Cognition and Personality Changes in Alzheimer's & Parkinson's Disease & Frontotemporal Lobar Degeneration
The aim of this study is to compare personality and social cognition changes, including emotion detection and self-awareness, and neuroanatomical correlates in patients, and how that affects the caregiver-patient relationship.
- Conditions
- Alzheimer's Disease, Parkinson's Disease, Frontotemporal Lobar Degeneration
- Trial name
- NCT02964611
- Testing
- Observational Study
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Change; Personality, Due to General Medical Condition
Motivational Interviewing Training for Medical Students: a Pilot Pre-post Study
Objective is to evaluate the impact of a basic training programme in motivational interviewing (MI) for medical students, by comparing the ability of students to promote behavioural changes through relationship skills and to…
- Trial name
- FEMEM (NCT03285828)
- Testing
- motivationnal interviewing training
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bicetre Hospital
Abnormal; Birth
Changes of Gas Values in Cord Blood Versus Time and Temperature
The pH levels of a neonatal at his birth are an important factor in establishing the connection between events that occurred during the actual time of birth, to the risk of a significant morbidity development in the future.
- Trial name
- NCT02785367
- Testing
- Cord blood samples
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Borderline Personality Disorders, Avoidant Personality Disorders
Changes in the Brain as Borderline Patients Learn to Regulate Their Emotions
Borderline Personality Disorder (BPD), a prevalent psychiatric disorder found in approximately 2% to 6% of the population and 20% of hospitalized psychiatric patients, has proven quite treatment resistant.
- Trial name
- NCT02465697
- Testing
- Reappraisal Training
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Obsessive-Compulsive Disorder
ITreatOCD: Predicting the Efficacy of Internet-based Cognitive Behavioral Therapy in Obsessive-compulsive Disorder
In the current study, the investigators will characterize obsessive-compulsive disorder (OCD) patients and healthy controls with a comprehensive clinical and neuroimaging assessment, focusing on the basic psychological processes…
- Trial name
- iTREATOCD (NCT05906069)
- Testing
- ICBT
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pedro Morgado
Enduring Personality Change
Effects of High-energy Nutritional Protein-based Bar on the Performance of Young Athletes
A study will be conducted in Lahore. Non probability convenience sampling technique will be applied on patients who will be allocated through computerized randomization into group A \& group B to collect data.
- Trial name
- NCT07065513
- Testing
- Normal diet, Normal diet plus nutritional protein-based bar
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Superior University
Self-harm, Personality Disorder, Borderline
Self-harm Behaviour Among the Most At-risk Adolescents
In the proposed study, three objectives will be pursued: 1. To develop a method to identify more effectively the acute and long-term risk of adolescents with the most threatening self-harm behaviours. 2.
- Conditions
- Self-harm, Personality Disorder, Borderline, Epigenetic Disorder, Non-Suicidal Self Injury
- Trial name
- SH-MARA (NCT05765864)
- Testing
- Enrollment questionnaire, General questionnaire1, General questionnaire2, General questionnaire3, Columbia Suicide Severity Rating Scale (CSSRS), The Brief Non-Suicidal Self-Injury Assessment Tool (B-NSSI-AT)
- Where
- 2 sites in Slovenia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana, Faculty of Medicine
Borderline Personality Disorder
Methylation Status of BDNF Gene After Dialectical Behavior Therapy in BPD
Borderline personality disorder (BPD) is a chronic and debilitating syndrome associated with considerable morbidity, mortality, and high rates of medical and psychiatric utilization services.
- Trial name
- NCT02134223
- Testing
- Dialectical behavior therapy, Treatment as Usual: any other drug or psychotherapy offered to participants, except DBT
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Attention Deficit Disorder With Hyperactivity, Mental Disorders Diagnosed in Childhood
Brain Changes in Children and Adolescents With Behavioral Problems
Purpose: This study will examine brain activity in children age 10-18 with disruptive behavior problems, including conduct disorder (CD), oppositional defiant disorder (ODD), and attention deficit hyperactivity disorder (ADHD)…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Mental Disorders Diagnosed in Childhood, Conduct Disorder
- Trial name
- NCT00104039
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Borderline Personality Disorder
Personality Change Study for Borderline Personality Disorder
Participants with borderline personality disorder will undergo an a 2 - 4 week baseline assessment to determine level of outcomes of interest in the absence of treatment.
- Trial name
- NCT06005129
- Testing
- Personality-Based Therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Dementia of Alzheimer Type, Dementia Frontotemporal
Multifactorial Approach to Dementia, Multicentric Study
The goal of this observational study is to assess the role of narcisistic personality disorder and life stressful events in conversion rate to dementia, using a three tier approach along three research lines employing subjects…
- Conditions
- Dementia of Alzheimer Type, Dementia Frontotemporal, Narcissistic Personality Disorder, Depression
- Trial name
- NCT05923307
- Where
- Argentina
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Daniel Serrani Azcurra
Pain, Individual Difference
Identifying Neuroimaging Biomarkers, Demographic, Personality and Sensory Factors for Predicting Extreme Pain Responses to Various Experimental Pain Stimulations in Healthy Subjects
The proneness to react to noxious stimuli varies widely between individuals and pain ratings of seemingly identical noxious stimuli may range from "no pain" to "excruciating pain" .
- Trial name
- NCT03436264
- Testing
- MRI
- Where
- Israel
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Health Behavior, Quality of Life
The Lake Nona Life Project
The Lake Nona Life Project aims to examine the health and wellness of participants over the course of multiple years, focusing on the links between health and wellness, longevity, quality of life, and human performance.
- Conditions
- Health Behavior, Quality of Life, Aging
- Trial name
- NCT02533804
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Learning Development, Obstetric
Adaptive Gamification in Obstetric Nursing
This pilot study, conducted at the University of Atlántico Medio, seeks to transform the training of future nurses through a "Precision Education" model, moving away from generic simulations to focus on learning adapted to the…
- Trial name
- NCT07434336
- Testing
- Adapted Gamified, Generic Gamified
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Servicio Canario de Salud
Personality, Coping Skills
Personality Change During Medical Residency
The Ethics Committee of Hospital and University Center of Coimbra (Portugal) complies, reports and is supervisioned by the Portuguese Ethics Committee.
- Trial name
- NCT01574924
- Testing
- No intervention.
- Where
- Portugal
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Coimbra