Clinical trials: Personality Disorder, Borderline
Borderline Personality Disorder (BPD), Healthy Controls Group - Age and Sex-matched
Affect-based Impulsivity in Borderline Personality Disorder
The purpose of this research study is to investigate how personality traits and neuroendocrine systems relate to decision-making patterns in individuals 18-45 years old.
- Trial name
- NCT06880640
- Testing
- Stress Induction
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
SCHIZOPHRENIA 1 (Disorder), Borderline Personality Disorder
Disorders of the Sense of Self and Physical Activity
Schizophrenia (SZ) patients with metabolic syndrome, patients with vestibular syndrome, and patients with borderline personality disorder, would benefit from physical activity (PA).
- Conditions
- SCHIZOPHRENIA 1 (Disorder), Borderline Personality Disorder, Vestibular Syndromes
- Trial name
- sensdesoi (NCT06817980)
- Testing
- Physical activity
- Where
- France
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Borderline Personality Disorder, Emotion Dysregulation
Testing an Alliance-Focused Dialectical Behaviour Therapy Training for Borderline Personality Disorder
The study evaluates the feasibility, acceptability, and effect sizes of two alliance-focused dialectical behavior therapy (DBT) training interventions to improve therapists' abilities to recognize and respond to alliance ruptures…
- Trial name
- NCT07119541
- Testing
- Alliance-Focused Dialectical Behavior Therapy plus Deliberate Practice, Alliance-Focused Dialectical Behavior Therapy plus Reflective Practice
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- York University
Borderline Personality Disorder
Personality Change Study for Borderline Personality Disorder
Participants with borderline personality disorder will undergo an a 2 - 4 week baseline assessment to determine level of outcomes of interest in the absence of treatment.
- Trial name
- NCT06005129
- Testing
- Personality-Based Therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Borderline Personality Disorder
The Effect of Oxytocin Administration on Interpersonal Cooperation in Borderline Personality Disorder Patients and Healthy Adults
The study will examine behavioral patterns and underlying neural correlates which distinguish patients with borderline personality disorder (BPD) from healthy subjects as they participate in a two-person trust game and will…
- Trial name
- NCT02225600
- Testing
- 40 IU Intranasal Oxytocin, 24 IU intranasal Oxytocin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Borderline Personality Disorder, Borderline Personality Disorder (BPD)
Conceptualizing Borderline Personality Disorder as a Relationship Use Disorder
This study aims to explore a novel conceptualization of Borderline Personality Disorder (BPD) as a "Relationship Use Disorder." The research proposes that BPD shares key features with behavioral addictions, specifically addiction…
- Conditions
- Borderline Personality Disorder, Borderline Personality Disorder (BPD), Bipolar Disorder (BD)
- Trial name
- TLUR (NCT07337889)
- Testing
- Relationship-use questionnaire
- Where
- France
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorder, Borderline Personality Disorder BPD
Perimenstrual Symptoms and Emotional Dysregulation in Autism
Emotional dysregulation (ED) is defined by difficulties in modulating the experience and expression of emotions, which are characterized by particularly marked reactivity, intensity, and duration.
- Conditions
- Autism Spectrum Disorder, Borderline Personality Disorder BPD, a Premenstrual Dysphoric Disorder (PMDD)
- Trial name
- MEDEA (NCT06871345)
- Testing
- Semi-structured interviews SCID, Self-report questionnaires, Momentary Ecological Assessment (EMA)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Borderline Personality Disorder, Relatives
PEGASUS - Improving Treatment for Patients With Emotionally Unstable Personality Disorder
The purpose of the PEGASUS study is to conduct a pilot trial to test the feasibility and acceptability of the PEGASUS intervention, adding a case manager and family-based interventions meetings to the existing psychiatric…
- Trial name
- NCT06563466
- Testing
- The experimental intervention PEGASUS, Treatment as usual
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group
ADOLESCENTS IMAGING USING fMRI: Feasibility Study
Impaired social cognition and cognitive control associated with borderline personality disorder (BPD) remain less explored. Recent Franco-Canadian study, has shown the feasibility of a neuroimaging tests in Quebec adolescents…
- Conditions
- Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group, Absence of Pathology on the CBCL and Ab-DIB for the Healthy Control Group, All Participants Were Euthymic at the Time of Task Administration
- Trial name
- ADO IMAGE (NCT07540429)
- Testing
- functional magnetic resonance imaging (fMRI)
- Where
- France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Etablissement Public de la Sante Mentale de la Somme
Borderline Personality Disorder (BPD)
Cortical Plasticity of the Tactile Mirror System in Borderline Personality Disorder
People with borderline personality disorder (BPD) show alterations in the empathic abilities, which may involve the functioning of the mirror neuron system in the somatosensory domain.
- Trial name
- SG2019-EXP2 (NCT06702215)
- Testing
- Cross-modal paired associative stimulation (cm-PAS) protocol
- Where
- Italy
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Borderline Personality Disorder BPD
Characterization of the Neural Bases of Mental Imagery in Individuals With Borderline Personality Disorder: An EEG Study
Borderline Personality Disorder (BPD) involves altered social cognition, notably dysfunctional processing of cues signaling potential social exclusion and heightened social pain.
- Trial name
- BABO (NCT07428200)
- Testing
- 2 Tasks : - stop signal reaction time and Cyberball then ill out an evaluation form
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Adolescent - Emotional Problem, Personality Disorders in Adolescence
Representations of the Body's Interior in Adolescence
Representations of the inner body in adolescence: developmental characteristics and specificities in borderline personality disorders.
- Conditions
- Adolescent - Emotional Problem, Personality Disorders in Adolescence, Body Representation, Borderline Personality Disorder
- Trial name
- RICA (NCT07407764)
- Testing
- Drawing of the inside of the body, interviews and questionnaires.
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Traumatic Brain Injury, Major Depressive Disorder
Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations
In the current study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in improving executive function across neuropsychiatric populations known to have deficits in this cognitive…
- Conditions
- Traumatic Brain Injury, Major Depressive Disorder, Bipolar Disorder, Schizophrenia
- Trial name
- NCT04296604
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Borderline Personality Disorder (BPD)
Neurobehavioral Mechanisms of Moral Reasoning: an EEG Study in Patients With Borderline Personality Disorder
We will investigate social cognition in patients with Borderline personality disorder (BPD) combined with electroencephalographic (EEG) measures.
- Trial name
- NCT07091409
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Borderline Personality Disorder
NEUROIMAGING OF ADOLESCENT BORDERLINE PERSONALITY DISORDER WITH AND WITHOUT POST-TRAUMATIC STRESS DISORDER
Borderline personality disorder (BPD) is a common mental disorder in adolescents with significant individual and societal repercussions, characterized over the long term by emotional hyperresponsiveness, relational instability…
- Trial name
- BorderStress (NCT04852744)
- Testing
- Brain MRI
- Where
- France
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Borderline Personality Disorder, Oxytocin
Interplay Between Oxytocin and Cortisol During Stress in Borderline Personality Disorder
This study aims to determine the feasibility and preliminary data on the interaction between oxytocin and cortisol during stress in borderline personnality disorder.
- Trial name
- OXT-CORT-BPD (NCT05357521)
- Testing
- stress test
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Self-harm, Personality Disorder, Borderline
Self-harm Behaviour Among the Most At-risk Adolescents
In the proposed study, three objectives will be pursued: 1. To develop a method to identify more effectively the acute and long-term risk of adolescents with the most threatening self-harm behaviours. 2.
- Conditions
- Self-harm, Personality Disorder, Borderline, Epigenetic Disorder, Non-Suicidal Self Injury
- Trial name
- SH-MARA (NCT05765864)
- Testing
- Enrollment questionnaire, General questionnaire1, General questionnaire2, General questionnaire3, Columbia Suicide Severity Rating Scale (CSSRS), The Brief Non-Suicidal Self-Injury Assessment Tool (B-NSSI-AT)
- Where
- 2 sites in Slovenia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana, Faculty of Medicine
Borderline Personality Disorder
Neural Mechanisms of Dialectical Behavioral Therapy in Patients with Borderline Personality Disorder
This research examines the behavioral and neural mechanisms of dialectical behavior therapy (DBT) effect in patients with borderline personality disorder (BPD).
- Trial name
- NeuroDBT (NCT06882330)
- Testing
- Dialectical behavior therapy
- Where
- Czechia
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Masarykova Univerzita
Borderline Personality Disorder, Adolescent Development
Emotional Regulation and Impulsivity Among Adolescents with Borderline Personality Disorder
This study aims to better understand the behavioral, neurobiological and hormonal underpinnings of stress and reward reactivity of adolescents suffering from borderline personality disorder compared to healthy adolescents by a…
- Trial name
- ADOLIMIS (NCT03209102)
- Testing
- Clinical assessment, Stress elicitation experiment, Structural and Functional MRI
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Borderline Personality Disorder
Stress & Social Cognition in BPD (part 2)
The investigators will examine how a combination of pharmacological mineralocorticoid receptor (MR) stimulation and psychosocial stress will influence prosocial behavior in patients with Borderline Personality Disorder (BPD)…
- Trial name
- SOKO-2 (NCT05310253)
- Testing
- Fludrocortisone, Trier Social Stress Test (TSST)
- Where
- Germany
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany