Clinical trials: Personality Disorders
Substance Use Disorders, Adolescent Behavior
The Canadian Underage Substance Use Prevention Trial
Despite having made some strides with respect to reducing adolescent drinking rates, illicit substance use and substance use disorders (SUDs) remain significantly above national targets for health promotion and disease prevention…
- Conditions
- Substance Use Disorders, Adolescent Behavior, Adolescent Development
- Trial name
- CUSP (NCT04198974)
- Testing
- PreVenture Training (PTtT), PreVenture Training+Implementation Facilitation
- Where
- 4 sites in Canada
- Volunteers
- 12,500 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Obsessive - Compulsive Disorder, Obsessive Compulsive Disorder (OCD)
Assessments of Obsessive-compulsive Symptoms in Patients With Substances Use Disorder
This observational, cross-sectional case-control study evaluates obsessive-compulsive symptoms among adults with substance use disorder compared with a demographically similar control group without substance use disorder.
- Conditions
- Obsessive - Compulsive Disorder, Obsessive Compulsive Disorder (OCD), Obsessive Compulsive Behavior, Substance Abuse Disorder
- Trial name
- NCT07395453
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Assiut University
Borderline Personality Disorder, Relatives
PEGASUS - Improving Treatment for Patients With Emotionally Unstable Personality Disorder
The purpose of the PEGASUS study is to conduct a pilot trial to test the feasibility and acceptability of the PEGASUS intervention, adding a case manager and family-based interventions meetings to the existing psychiatric…
- Trial name
- NCT06563466
- Testing
- The experimental intervention PEGASUS, Treatment as usual
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
SCHIZOPHRENIA 1 (Disorder), Borderline Personality Disorder
Disorders of the Sense of Self and Physical Activity
Schizophrenia (SZ) patients with metabolic syndrome, patients with vestibular syndrome, and patients with borderline personality disorder, would benefit from physical activity (PA).
- Conditions
- SCHIZOPHRENIA 1 (Disorder), Borderline Personality Disorder, Vestibular Syndromes
- Trial name
- sensdesoi (NCT06817980)
- Testing
- Physical activity
- Where
- France
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Healthy
Outcome Following Antidepressant Treatment on Possible Endo-Phenotypes for Major Depression
The purpose of this study is to determine whether outcome following antidepressant treatment can be used as a tool to evaluate endo-phenotypes for depression.
- Trial name
- NCT00386841
- Testing
- Escitalopram
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Borderline Personality Disorder
Assessment of Sense of Identity in Patients Diagnosed With Borderline Personality Disorder. A Pilot Study
One of the key features and long considered a fundamental element of Borderline Personality Disorder is the disruption of identity.
- Trial name
- MASB (NCT04948905)
- Testing
- Evaluation using the Self-Defining Memory Questionnaire
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Premature Infant, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)
This study is being done to see if outcomes for both a premature infant's parents and the infant born prematurely who have spent time in the neonatal intensive care unit (NICU) can be improved through parent cognitive behavioral…
- Conditions
- Premature Infant, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Development, Child, Parent-Child Relations
- Trial name
- PreVNT (NCT03906435)
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Emotion Regulation, Anxiety Disorders
Efficacy of a Web-Based Emotion Regulation Training in a Transdiagnostic Sample
This two-armed randomized controlled trial investigates the efficacy of a web-based emotion regulation intervention in a transdiagnostic sample.
- Conditions
- Emotion Regulation, Anxiety Disorders, Depression, Eating Disorders
- Trial name
- NCT06183333
- Testing
- Heidelberg Emotion Regulation Training
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Infant Development
Maternal Adversity, Vulnerability and Neurodevelopment
Maternal Adversity Vulnerability and Neurodevelopment (MAVAN) project is a prospective community-based, pregnancy and birth cohort of Canadian mother-child dyads.
- Conditions
- Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Infant Development, Infant Behavior
- Trial name
- MAVAN (NCT03434457)
- Where
- Canada
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Affective Spectrum Symptoms
Gene-environment Interactions in Families With Adolescents (Gen-omgevingsinteracties in Gezinnen Met Adolescenten)
English: The main purpose of this study is to investigate the developmental trajectories of parents and adolescents in the Flemish region of Belgium.
- Trial name
- GiGA (NCT05716412)
- Where
- 2 sites in Belgium
- Volunteers
- 1,326 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Expanded Game Squad for Neurodiverse Youth
The proposed study will pilot the use of an adapted Game Squad intervention aimed at improving physical activity and other important health behaviors (nutrition, sleep hygiene, screen time habits) for children and adolescents…
- Conditions
- Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Health Behavior, Developmental Disorder
- Trial name
- NDGameSquad (NCT03665415)
- Testing
- NDGameSquad
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Merrimack College
Change; Personality, Due to General Medical Condition
Motivational Interviewing Training for Medical Students: a Pilot Pre-post Study
Objective is to evaluate the impact of a basic training programme in motivational interviewing (MI) for medical students, by comparing the ability of students to promote behavioural changes through relationship skills and to…
- Trial name
- FEMEM (NCT03285828)
- Testing
- motivationnal interviewing training
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bicetre Hospital
Mild Cognitive Impairment, Behavioral Symptoms
The Moderating Roles of Social Support, Coping Resources and Personality and Mediating Role of Self-esteem on the Impact of Cognitive Deficit on Neuropsychiatric Symptoms Among Persons With Mild Cognitive Impairment: A Mixed-method Sequential Explanatory Design
This is a sequential mixed study to test the hypothesized models with seven hypotheses of the relationship between cognitive deficit (subject and objective) and neuropsychiatric symptoms (NPS) among persons with mild cognitive…
- Trial name
- NCT04085107
- Testing
- Face-to-face interviews
- Where
- Hong Kong
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Intergenerational Relations
Maternal Psychopathology and Offspring Mental Health (PSI_PER)
Pregnant women consecutively referred to the Perinatal Psychiatric Outpatient Department, those in charge of the Psychiatric Outpatient Department and pregnant healthy controls from the general population will be recruited on a…
- Trial name
- PSI_PER (NCT03897816)
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Schizotypal Personality Disorder, SPD
CRT-Guanfacine for SPD
This is a study to assess the efficacy augmenting cognitive remediation therapy (CRT) with a pharmacological agent for individuals with schizotypal personality disorder (SPD).
- Trial name
- NCT02524899
- Testing
- Cognitive Remediation Therapy, Guanfacine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Anxiety Disorder, Head Injury
Neuropsychological Evaluation of Psychiatric and Neurological Patients
This study will allow researchers to use various types of tests to evaluate cognitive and sensory functions. These tests, referred to as "batteries" will evaluate attention, executive functions, general intellectual functioning…
- Conditions
- Anxiety Disorder, Head Injury, Mood Disorder, Schizophrenia
- Trial name
- NCT00001192
- Where
- 7 sites in United States, France and 1 more
- Volunteers
- 4,300 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Anxiety, Attachment Disorder
A Good Start to Life - an Early Cross-sectorial Intervention
The aim of the project is to develop and evaluate an interdisciplinary and cross-sectorial intervention targeting pregnant women with psychosocial vulnerabilities.
- Conditions
- Anxiety, Attachment Disorder, Maternal Sensitivity, Depression
- Trial name
- NCT03190707
- Testing
- Intervention
- Where
- Denmark
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Intersectoral Research Unit for Health Services
Anxiety
Reducing Anxiety Levels Through the Dharma Life App-Based and Mentor-Based Program Targeting Personality Characteristics: A Randomized Control Trial
The purpose of this study was to examine whether an app- and mentor-based program reduced anxiety among individuals reporting difficulties with anxiety.
- Trial name
- NCT06138652
- Testing
- App
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Dharma Life Sciences LLC
Paranoia, Psychotic Disorders
Racial Disparities in the Expression of Paranoia
Paranoia is a pattern of thinking in which people feel suspicious or believe others may want to harm them. It can occur in many people, not only those with a mental health diagnosis, and it can affect daily life, relationships…
- Trial name
- NCT07460453
- Testing
- Guided Visual Imagery Task
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Indiana University
Antisocial Behavior, Aggression
The Effect of Repeated Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior
This study investigates the relationship between prefrontal cortex activity and antisocial and aggressive behavior, and risk factors for such behavior.
- Trial name
- NCT02674516
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania