Clinical trials: Personality Disorders
Borderline Personality Disorders, Avoidant Personality Disorders
Changes in the Brain as Borderline Patients Learn to Regulate Their Emotions
Borderline Personality Disorder (BPD), a prevalent psychiatric disorder found in approximately 2% to 6% of the population and 20% of hospitalized psychiatric patients, has proven quite treatment resistant.
- Trial name
- NCT02465697
- Testing
- Reappraisal Training
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Parenting, Development, Child
Pathways for Parents After Incarceration Feasibility Study
The purpose of this study is to learn how to better support fathers and their families after incarceration. It will test an intervention that promotes healthy development for children of previously incarcerated fathers and the…
- Conditions
- Parenting, Development, Child, Behavior
- Trial name
- NCT04525703
- Testing
- Pathways for Parents after Incarceration
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Psychosis;Schizophrenic, Personality Disorders
The Impact of the COVID-19 (SARS-CoV-2 Disease) on Psychopathology
The outbreak of the SARS-CoV-2 pandemic may be considered a traumatic phenomenon. In a sample of subjects suffering from different psychiatric disorders, psychopathological status and Post-Traumatic Stress Disorder (PTSD)…
- Conditions
- Psychosis;Schizophrenic, Personality Disorders, Mood Disorders, Anxiety Disorders
- Trial name
- NCT04694482
- Testing
- Psychometric scale administration
- Where
- Italy
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Family Caregivers
The Impact of a Psycho-educational Program for Family Members of Individuals With Borderline Personality Disorder
This is a prospective, single-arm, open-label study to assess the impact of the Family Connections (FC) program on various factors including burden, grief and several clinical variables (i.e., depressive symptoms, family…
- Trial name
- NCT06074289
- Testing
- Family connections program
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Major Depressive Episode, Major Depressive Disorder
Depression-Reduction by Accelerated Personalized NeuroModulation and Its Effects on Sleep
Advances in repetitive transcranial magnetic stimulation (rTMS) protocols with intermittent theta-burst stimulation (iTBS) have significantly decreased the duration for one single session and thereby enabled accelerated treatment…
- Conditions
- Major Depressive Episode, Major Depressive Disorder, Borderline Personality Disorder
- Trial name
- DREAMS (NCT04832750)
- Where
- Germany
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Oldenburg
Alzheimer's Disease, Parkinson's Disease
Social Cognition and Personality Changes in Alzheimer's & Parkinson's Disease & Frontotemporal Lobar Degeneration
The aim of this study is to compare personality and social cognition changes, including emotion detection and self-awareness, and neuroanatomical correlates in patients, and how that affects the caregiver-patient relationship.
- Conditions
- Alzheimer's Disease, Parkinson's Disease, Frontotemporal Lobar Degeneration
- Trial name
- NCT02964611
- Testing
- Observational Study
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Expanded Game Squad for Neurodiverse Youth
The proposed study will pilot the use of an adapted Game Squad intervention aimed at improving physical activity and other important health behaviors (nutrition, sleep hygiene, screen time habits) for children and adolescents…
- Conditions
- Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Health Behavior, Developmental Disorder
- Trial name
- NDGameSquad (NCT03665415)
- Testing
- NDGameSquad
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Merrimack College
Heart Disease, Physical Frailty
Genetics and Epidemiology of Aging Associated Conditions in the Sardinian Population
Background: The island of Sardinia, an Italian region, has a population that is highly interrelated. Researchers have developed the SardiNIA longitudinal study to examine the possible genetic factors that predispose individuals…
- Conditions
- Heart Disease, Physical Frailty, Exaggerated Personality Traits
- Trial name
- NCT00182949
- Where
- Italy
- Volunteers
- 6,926 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Dyssocial Behavior, Antisocial Personality Disorder
Antisocial Behavior: Passing From Parent to Child to Grandchild
Antisocial behavior often occurs in different generations within the same family. However, it is not known what factors contribute to this passing of antisocial behavior from parent to child to grandchild.
- Trial name
- NCT00060788
- Where
- Mauritius
- Volunteers
- 663 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Schizophrenia, Depression
Peer Support for Increasing Physical Activity in People With Serious Mental Illnesses
This study will determine the effectiveness of a peer support system in increasing physical activity and effecting health behavior change in people with serious mental illnesses.
- Conditions
- Schizophrenia, Depression, Bipolar Disorder, Anxiety Disorders
- Trial name
- NCT00458094
- Testing
- Physical activity intervention with peer support (PA+PS), Physical activity intervention without peer support (PA)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Acquired Immunodeficiency Syndrome, Alcoholism
Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits
We propose to conduct a multifactorial genetic study of cancer risk-related behaviors and other complex human characteristics. The main areas of interest are tobacco smoking, excess alcohol consumption, psychological traits, and…
- Conditions
- Acquired Immunodeficiency Syndrome, Alcoholism, HIV Infection, Neoplasm
- Trial name
- NCT00001500
- Where
- United States
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Disaster; Personality, Disorder, Mood
The Effect of Virtual Reality-Based Disaster Education Given to Nursing Students on Disaster Preparedness
It is thought that, as a result of the virtual reality-based disaster training given to nursing students, the psychological preparedness of nursing students who will work before, during and after the disaster will increase in…
- Trial name
- NCT06253156
- Testing
- virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Baskent University
Borderline Personality Disorder, Alcohol Use Disorder
Psychodynamic Therapy For Co-occurring Borderline Personality Disorder and Alcohol Use Disorder
The purpose of the study is to determine the feasibility and effectiveness of a modified form of psychodynamic psychotherapy for persons suffering from co-occurring borderline personality disorder and an alcohol use disorder.
- Trial name
- NCT00145678
- Testing
- Psychodynamic Therapy, Optimized Community Care
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Attention Deficit and Disruptive Behavior Disorders, Child Behavior Disorders
Study of Children at Risk for Disruptive Behavior Disorders
A conduct disorder is characterized by repetitive and persistent patterns of behavior where the basic rights of others and rules are violated.
- Conditions
- Attention Deficit and Disruptive Behavior Disorders, Child Behavior Disorders, Passive-Aggressive Personality Disorder
- Trial name
- NCT00001233
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Adolescent - Emotional Problem, Personality Disorders in Adolescence
Representations of the Body's Interior in Adolescence
Representations of the inner body in adolescence: developmental characteristics and specificities in borderline personality disorders.
- Conditions
- Adolescent - Emotional Problem, Personality Disorders in Adolescence, Body Representation, Borderline Personality Disorder
- Trial name
- RICA (NCT07407764)
- Testing
- Drawing of the inside of the body, interviews and questionnaires.
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Schizophrenia Spectrum and Other Psychotic Disorders, Bipolar and Related Disorders
Ascertaining Diagnosis Classification With Elicited Speech
Cross-sectional observational study of the relationship between speech patterns and psychiatric symptoms and disorders.
- Conditions
- Schizophrenia Spectrum and Other Psychotic Disorders, Bipolar and Related Disorders, Depressive Disorder, Anxiety Disorders
- Trial name
- ACES (NCT05601063)
- Testing
- Winterlight Speech Assessment
- Where
- United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Alzheimer Disease, Semantic Dementia
Memory and Social Interactions
Memory and social interaction are intimately linked. On the one hand, social interaction is a privileged context for learning, and on the other hand, appropriate social interactions involve remembering the partners encountered…
- Trial name
- MEM&SO (NCT05800028)
- Testing
- Learning new information
- Where
- France
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Personality Disorder, Borderline
Evaluating the Coordinated National Implementation of DBT in Ireland
This study aims to evaluate the coordinated implementation of Dialectical Behaviour Therapy in Community Mental Health Services in Ireland.
- Trial name
- NCT03180541
- Testing
- Dialectical Behaviour Therapy
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Health Service Executive, Ireland
Alcohol Abuse, Drug Abuse
Adventure: Teacher Delivered Personality-targeted Interventions for Substance Misuse
Several personality factors have been shown to be associated with risk for alcohol and substance misuse, and differentiate substance abusers based on clinical profile, treatment response and susceptibility to other forms of…
- Conditions
- Alcohol Abuse, Drug Abuse, Depression, Panic Disorder
- Trial name
- Adventure (NCT00776685)
- Testing
- Personality-targeted interventions
- Where
- United Kingdom
- Volunteers
- 3,190 people, healthy volunteers welcome
- Sponsor
- King's College London
Borderline Personality Disorder, BPD
Examining Dose-Related Effects of Oxytocin on Social Cognition Across Populations
Social cognition impairment is critical to the pathology and morbidity of a number of psychiatric disorders, including the schizophrenia spectrum, the autism spectrum and the personality disorders, thus representing a dimension…
- Conditions
- Borderline Personality Disorder, BPD, Schizotypal Personality Disorder, SPD
- Trial name
- NCT02149823
- Testing
- Syntocinon 24 Intranasal Units (IU), Syntocinon 40 Intranasal Units (IU)
- Where
- 2 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Maria de las Mercedes Perez Rodriguez