Clinical trials: Pervasive Development Disorders
Autism Spectrum Disorder, Anesthesia
Observational Prospective Study on Behavioral Outcomes of Children With Autism Spectrum Disorder (ASD) in Comparison to Those Without Neurodevelopmental Diagnoses
Autism Spectrum Disorder (ASD) is the fastest growing neurodevelopmental disorder in the world. Approximately 1% of the population worldwide is affected by this disorder.
- Trial name
- NCT02707939
- Testing
- Observation
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorder, Insomnia
SweetDreams Sleep Study for Children With Autism
This proposal will acquire preliminary data on the feasibility and effectiveness of an innovative and scalable strategy for improving access to effective sleep health care for preschool-aged children with Autism Spectrum Disorder…
- Trial name
- NCT04452045
- Testing
- SweetDreams
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Autism
Autism Intervention Research Network for Behavioral Health (AIR-B II): Deployment Into Elementary Schools
The primary goal of this study is to identify efficacious and cost effective intervention strategies that can improve academic and psychological outcomes for children with ASD, and can be feasibly be implemented at fidelity by…
- Trial name
- AIR-B II (NCT01724047)
- Testing
- Playground Intervention, STAT Intervention
- Where
- 3 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Health Resources and Services Administration (HRSA)
Depression, Autism
Implementation of the Parents Taking Action in Paraguay
The principal aim of this study is to conduct a single group design pilot of a psychoeducational caregiver training (i.e., culturally adapted Parents Taking Action) with a group of family caregivers of young children with autism…
- Trial name
- PTA-Paraguay (NCT05780138)
- Testing
- Parents Taking Action
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Autism Spectrum Disorder, Anxiety
Open-label Pilot Study Synbiotic Treatment for Autism Spectrum Disorder
The objective of this study is to conduct a open-label pilot study evaluating the feasibility, tolerability and preliminary efficacy of a 12-week course of synbiotic in improving anxiety symptoms in children with ASD.
- Trial name
- NCT06126185
- Testing
- 12-week course of synbiotic
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Weight Gain, Autism Spectrum Disorder
Pragmatic Trial Comparing Weight Gain in Children With Autism Taking Risperidone Versus Aripiprazole
This study aims to compare two FDA approved medications (aripiprazole and risperidone) for the treatment of behavioral dysregulation in children with autism spectrum disorders.
- Conditions
- Weight Gain, Autism Spectrum Disorder, Medication Side Effect
- Trial name
- NCT04903353
- Testing
- Comparison of Risperidone and Aripiprazole
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Autism
Motor Function Assessment and VR-based Motor Training in Adults With Autism Spectrum Disorder
The goal of this clinical trial is to learn if autism affect motor functions, including muscle strength, balance, and motor control? Additionally, understanding the motor functions, cognitive functions, and brain activation in…
- Trial name
- NCT07134569
- Testing
- VR-based motor training
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Pregnancy, Autistic Disorder
Screening for Metabolic Problems in Mothers of Children With Autism and Typically Developing Children
The purpose of this research study is to screen for metabolic abnormalities that are maternal risk factors for having a child with autism.
- Conditions
- Pregnancy, Autistic Disorder, Folic Acid Deficiency
- Trial name
- NCT02674022
- Testing
- Prenatal supplement
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Autism Spectrum Disorders
The Development of Younger Siblings of Children With Autism Now at 10 Years of Age
Background: Autism is a complex developmental disorder involving difficulties in verbal and nonverbal communication, social-emotional functioning, and markedly restricted interests and activities.
- Trial name
- NCT00695812
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Clinical, Environmental, Neurocognitive, Brain Imaging, and Genetic Validity of Autism and ADHD
The behavioral patterns, neurocognitive and social impairments, and high heritability are the common characteristics of autism spectrum disorders (ASD) and attention-deficit hyperactivity disorder (ADHD), the two most common…
- Trial name
- NCT00916851
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder, Autism
Online Pivotal Response Treatment Training in Autism Spectrum Disorder
This is a research study that will assess the effects of a Pivotal Response Treatment Online Training Course (PRT-O) for training parents of children with Autism Spectrum Disorder (ASD).
- Trial name
- PRT-O (NCT06523387)
- Testing
- Pivotal Response Treatment Online (PRT-O) Course
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autism Spectrum Disorders
Replication of the The Multi-Media Social Skills Project for Adolescents With Autism Spectrum Disorders
The objective of this study is to validate a social skills training program manual for adolescents (ages 13-17) with Asperger's Syndrome or high functioning autism.
- Trial name
- NCT01836965
- Testing
- Social Skills Intervention
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Autism, Autism Spectrum Disorder
Optimizing Outcomes for Young Autistic Children
The overarching goal of the proposed study is to: (a) determine how best to sequence two parent-mediated interventions: a social communication intervention (Project ImPACT, Improving Parents as Communication Teachers) and a…
- Trial name
- NCT05926687
- Testing
- Social Communication, Disruptive Behavior, Social Communication + Reduce Frequency
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Autism Spectrum Disorder, Patient Engagement
Testing Design Thinking Methodology to Engage Hispanic and Latino Families of Autistic Children in Research.
The goal of this study is to compare the level of engagement in the Hispanic and Latino parents of autistic children and culturally adapt the protocol of Ayres Sensory Integration to improve participation and health outcomes.
- Trial name
- NCT06111092
- Testing
- Design Thinking, Focus Groups
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Sleep Problems
Understanding Sleep Problems in Children With Autism Spectrum Disorder
The investigators will examine whether sleep problems in children with autism spectrum disorder (ASD) are related to alterations in the production of melatonin (MT), a hormone that plays an important role in regulating sleep-wake…
- Trial name
- REST (NCT00691080)
- Where
- 3 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Autism Disorders and Maternal Stress, Development Delay
Perinatal Autism Genetics and Epigenetics Study
The University of Iowa's Center for Disabilities and Development is researching how pregnancy, early childhood experiences, and genetic factors influence child development, with a focus on autism spectrum disorder (ASD).
- Conditions
- Autism Disorders and Maternal Stress, Development Delay, Prenatal Stress, Social Behavior
- Trial name
- PAGES (NCT07738003)
- Testing
- Change in child's DNA methylation, Perinatal stress, Early social experience
- Where
- United States
- Volunteers
- 7,200 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Autism Spectrum Disorder
STEPS Implementation Trial
This study will inform understanding of how to support emerging adults with autism spectrum disorder (ASD). The investigators will use a theoretically informed and research-based transition support program developed for people…
- Trial name
- NCT05695885
- Testing
- STEPS, Services as usual (SAU)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Developmental Disability, Autism Spectrum Disorder
Association Between Motor Skills and Sensory Profiles in Children With Typical and Atypical Development Aged 4 to 11 Years
Background and Justification Childhood developmental disorders, such as Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD), and Developmental Coordination Disorder (DCD), pose significant challenges…
- Conditions
- Developmental Disability, Autism Spectrum Disorder, Development Coordination Disorder, Attention Deficit Disorder With Hyperactivity
- Trial name
- MOTISEN (NCT06764810)
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Autism Spectrum Disorder
Transcranial Magnetic Stimulation (rTMS) and Autism.
In this protocol we aim to use rTMS to better characterize STS role in normal and abnormal social cognition. With that purpose, we will measure the effect of inhibitory and excitatory rTMS on the fixation time on social scenes…
- Trial name
- TMSAUTISME (NCT01648868)
- Testing
- Transcranial Magnetic Stimulation (rTMS)
- Where
- France
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder
Early Screening of Autism Spectrum Disorder in General and Pediatric Practices
Early screening for Autism Spectrum Disorder has been validated using different screening tools, in particular M-CHAT-R and ITC in different countries. Unfortunaltely, in France, they are not often used.
- Trial name
- KitCAT (NCT04274127)
- Testing
- early detection kit composed of 2 questionnaires (M-CHAT-R + CSBS-ITC)
- Where
- France
- Volunteers
- 1,211 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier