Clinical trials: Philadelphia Chromosome Negative
Cholecystolithiasis, Cholecystectomy
Does Cholecystectomy Increase the Esophageal Alkaline Reflux? Evaluation by Impedance-pH Technique
Publications with different conclusions are available with regard to the correlations between the cholecystolithiasis, cholecystectomy and gastroesophageal reflux disease (GERD).
- Conditions
- Cholecystolithiasis, Cholecystectomy, Gastroesophageal Reflux
- Trial name
- NCT01047085
- Testing
- impedance pH measurement
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Term Pregnancy, Doppler Parameters
Relationship Between Delivery Route and Fetal Complications With Doppler Indices and CPR Parameters
Term pregnancies within their 37-41 gestational week, who were planned to undergo induction of labor, were included in the study.
- Conditions
- Term Pregnancy, Doppler Parameters, Induction of Labor, Fetal Complications
- Trial name
- Doppler (NCT04158609)
- Testing
- Doppler flow indices assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
GERD (Gastroesophageal Reflux Disease)
Normal Values of Ambulatory 24-hour Oesophageal pH-impedance Monitoring in an Indian Cohort of Participants
This study aims to determine normal 24-hour pH-impedance monitoring values, including acid exposure time (AET), in healthy Indian adults. It will help improve GERD diagnosis in India by providing population-specific data.
- Trial name
- NCT06928350
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Healthy
Evaluation of Gastrointestinal pH and Motility After the Consumption of Milk
This pilot study is designed as a monocentric, open label, interventional, parallel arms, controlled clinical trial. The aim of the study is to assess the gastrointestinal pH and motility after the consumption of milk.
- Trial name
- ROVER (NCT05471206)
- Testing
- Milk and SmartPill intakes
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Lactalis
Pulmonary Arterial Hypertension, Healthy
A Study of Pulmonary Hypertension Peripheral Limitations
The investigators are doing this research study to compare whole body aerobic training with isolated leg training (with weights) and its impact on effectiveness in symptoms and quality of life in patients with Pulmonary Arterial…
- Trial name
- NCT05968859
- Testing
- Aerobic Training, Leg Training
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Gastroesophageal Reflux Disease
PH Metry Study to Compare the Antacid Activity of Z0063 Versus Gaviscon Double Action Tablets, in Healthy Adult Subjects
Primary Objective: Pharmacodynamics: assessment by pH metry of the change in gastric pH (antacid activity) of Z0063, in comparison to the effect of Gaviscon Double Action Tablets, in healthy adult subjects.
- Trial name
- NCT03069963
- Testing
- Z0063, Gaviscon
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sanofi
Colon Cancer, Polyps
Evaluation of Stool Tagging for Improved Patient Compliance
Computed tomography (CT) colonography has gained widespread multi-disciplinary interest as an evolving noninvasive colorectal screening examination, with the potential of improved patient compliance.
- Trial name
- NCT00124163
- Testing
- Imaging procedure of CT colonography
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Center for Diagnostic Imaging
Pulmonary Hypertension Due to Lung Diseases
Collagen Fingerprinting for Stratification of Pulmonary Hypertension (PH) Patients
Chronic lung diseases such as pulmonary fibrosis and chronic obstructive pulmonary disease (COPD) can lead to pulmonary hypertension.
- Trial name
- NCT07498244
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Electrolyte Disturbance, Saliva Altered
Effects of Cardamom and Fennel on Salivary pH and Anti Microbial Activity
Dental caries is the most prevalent infectious disease related to oral health.. Although significant advances have been made on a global front to prevent caries, studies show its incidence is on the rise making it one of the…
- Trial name
- NCT05245019
- Testing
- cardamom, fennel
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Karachi
Saliva Altered, Plaque
Xylitol Chewable Tablets Versus Xylitol Chewing Gum in Geriatric Bedridden Patients
This study will be conducted to evaluate the effectiveness of using dissolving Xylitol chewable tablets versus xylitol chewing gum with bedridden geriatric patients in increasing salivary pH and decreasing bacterial count in both…
- Trial name
- NCT03877705
- Testing
- Listerine ready tabs
- Where
- Egypt
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthodontic Appliance Complication, Lactobacillus Infection
SPACE MAINTAINERS EFFECTS ON ORAL MİCROFLORA
Space maintainers are used to preserve the space after premature loss of teeth but they could effect some factors that play a role in caries formation.
- Conditions
- Orthodontic Appliance Complication, Lactobacillus Infection, Dental Caries in Children, Streptococcus, Other Specified Group
- Trial name
- NCT04749654
- Testing
- The Salivary pH measured, The saliva flow rate was measured, Streptococcus mutans and Lactobacillus counts in saliva were measured
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Multiple Myeloma, Non-Hodgkin Lymphoma
Ph I Trial of NAM NK Cells and IL-2 for Adult Pts With MM and NHL
This is a phase I trial with pilot expansion of HLA-haploidentical or HLA-mismatched related donor nicotinamide expanded-natural killer (NAM-NK) cell based therapy for patients with relapsed or refractory multiple myeloma (MM) or…
- Conditions
- Multiple Myeloma, Non-Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma, Mantle-Cell Lymphoma
- Trial name
- NCT03019666
- Testing
- Nicotinamide Expanded Haploidentical or Mismatched Related Donor Natural Killer Cells
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Dental Caries Prevention
Silver Nanoparticle vs Chlorhexidine Mouthwashes for Reducing Streptococcus Mutans and Improving Salivary pH in Children
Dental caries remains one of the most common chronic diseases in children, with Streptococcus mutans playing a major role in its development.
- Trial name
- SMILE (NCT07728409)
- Testing
- Silver nanoparticle mouthwash (10 ppm), Chlorhexidine mouthwash (0.2%)
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gastric pH Control
Magnesium Pantoprazole 20mg b.i.d. vs Magnesium Pantoprazole 40mg q.d. on Intragastric Acid Inhibition
The purpose of this study is to determine if magnesium pantoprazole 20 mg twice a day (b.i.d.), maintains gastric pH above 4 during a longer percentage of time than magnesium pantoprazole 40 mg once a day (qd).
- Trial name
- NCT01499693
- Testing
- Magnesium Pantoprazole 20 mg, Magnesium Pantoprazole 40 mg
- Where
- Mexico
- Volunteers
- healthy volunteers welcome
- Sponsor
- Takeda
Salivary pH
Effect of Matcha Tea Versus Green Tea on Salivary pH and Flow Rate in High Caries Risk Patients
Objectives: To evaluate the effect of green tea versus matcha tea on the salivary pH in high caries risk patients. Materials and methods: Total number of high caries risk patients were randomized into two equal groups (n=).
- Trial name
- NCT06504706
- Testing
- Matcha Tea, Green Tea
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy Volunteers
Clinical Evidence of pH Dependent ß2 Adrenergic Transport Mechanisms in the Airway
The purpose of this study was to determine if airway pH has an effect on albuterol-induced vasodilation in the airway. Methods: Ten healthy volunteers performed the following respiratory maneuvers: quiet breathing, hypocapnic…
- Trial name
- NCT01216748
- Testing
- quiet breathing, Hypocapnic Hyperventilation, Hypercapnic Hyperventilation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Miami
Healthy Participants
A Trial to Evaluate the Effect of Esomeprazole on the Pharmacokinetics of Emraclidine in Healthy Adult Participants
The primary purpose of this study is to evaluate the potential of gastric pH-dependent drug-drug interaction effect of esomeprazole, a proton pump inhibitor (PPI), on the pharmacokinetics (PK) of emraclidine in healthy adult…
- Trial name
- NCT06366243
- Testing
- Emraclidine, Esomeprazole
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cerevel Therapeutics, LLC