Clinical trials: Phobias Spiders
Spider Fear, Arachnophobia
Feasibility of an Online Modeled Exposure in Spider Fearful Individuals
The effectiveness of an optimized group exposure treatment is investigated in spider-fearful individuals. Participants will undergo an optimized standardized exposure treatment.
- Trial name
- OMEX (NCT06182709)
- Testing
- online psychoeducation video + modeled exposure, live psychoeducation video + modeled exposure, group exposure
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Philipps University Marburg
Arachnophobia, Cynophobia
Telemedicine-Based Virtual Reality Clinic for the Treatment of Phobias
The purpose of this study is to assess the feasibility of conducting a randomized controlled efficacy trial comparing the delivery of exposure therapy via a telemedicine-based virtual reality clinic (Doxy.me VR) vs.
- Conditions
- Arachnophobia, Cynophobia, Ophidiophobia
- Trial name
- NCT06302868
- Testing
- Telemedicine Exposure Therapy Using Photos and Videos, Telemedicine-Based Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of South Florida
Spider Phobia
Gamification in the Treatment of Spider Phobia
Mobile applications are more and more considered when implementing programs for treating mental disorders. The study aims to reduce avoidance and fear of spiders in spider-fearful individuals by combining exposure principles with…
- Trial name
- NCT04423783
- Testing
- 7-day exposure therapy via self-developed app according to (Haberkamp et al., submitted), Therapist-guided one-session online exposure therapy according to (Öst, 1989)
- Where
- 2 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Anke Haberkamp
Phobia, Specific
Influence of Valproic Acid on Extinction-based Therapy in Patients With Fear of Spiders.
The purpose of this study is to evaluate whether valproic acid in combination with fear memory reactivation is useful to enhance treatment stability of exposure therapy for specific phobia.
- Trial name
- VALPRO (NCT02789813)
- Testing
- Valproic Acid, Fear reactivation, No fear reactivation
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Acrophobia, Arachnophobia
3D Video Virtual Reality Exposure Therapy Study
This study seeks to examine a Virtual Reality Exposure Therapy (VRET) using the 3D Video Virtual Reality (VR) technology for the fear of spiders.
- Trial name
- 3D-VVRET (NCT02584387)
- Testing
- 3D Video Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Specific Phobia
Extinction Generalization in Exposure Therapy
Patients with anxiety disorders oftentimes express fear responses to more than only one fear-inducing object. The principal aim of this study is to examine whether the beneficial effects of exposure on fear reduction in spider…
- Trial name
- NCT03031002
- Testing
- Exposure treatment for spider fear
- Volunteers
- 77 people
- Sponsor
- Ruhr University of Bochum
Arachnophobia, Phobia
TMS and Exposure Therapy
Spider phobia is an exceedingly common phobia throughout the world. The current standard treatment involves exposure therapy, which consists of a series of brief exposures of an individual to the thing they fear, in this case…
- Trial name
- NCT04019054
- Testing
- Intermittent Theta Burst Stimulation (iTBS), Ventromedial Prefrontal Cortex (vmPFC), Intermittent Theta Burst Stimulation (iTBS), vertex
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, Los Angeles
Phobia, Specific
The Impact of Sex Hormones on One-session Treatment for Spider Phobia in Women
The purpose of this study is to determine whether levels of sex hormones (including estrogen and progesterone) influence women's response to treatment for Specific Phobia of spiders.
- Trial name
- NCT02622087
- Testing
- One-Session-Treatment
- Where
- Australia
- Volunteers
- 90 people
- Sponsor
- The University of New South Wales
Fear of Spiders, Fear of Heights
Generalized Fear Extinction to Untreated Fear Stimuli in Specific Phobias After Exposure
This study investigates whether a one-session exposure treatment for spider-related stimuli can lead to a generalization of extinguished fear to height-related stimuli in individuals with comorbid fear of spiders and fear of…
- Trial name
- NCT03907345
- Testing
- Exposure
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Ruhr University of Bochum
Claustrophobia, Obsessive-Compulsive Disorder
Efficacy of Targeted Memory Reactivation for Enhancing Exposure Therapy
This study evaluates whether a scent applied during exposure therapy and during subsequent sleep will increase the durability of treatment effects for individuals with fear of spiders, contamination, and enclosed spaces.
- Conditions
- Claustrophobia, Obsessive-Compulsive Disorder, Arachnophobia
- Trial name
- NCT04663672
- Testing
- Experimental Scent, Control Scent, No-Scent Control
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- University of Texas at Austin
Specific Phobia, Arachnophobia
Use of Safety Behaviors in Exposure Therapy for Arachnophobia
This study examines the impact of safety behaviors (i.e., unnecessary protective actions) on outcomes of exposure therapy for spider phobia.
- Conditions
- Specific Phobia, Arachnophobia, Spider Phobia
- Trial name
- NCT04470882
- Testing
- Exposure with faded safety behaviors, Exposure without safety behaviors, Exposure with unfaded safety behaviors
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Nevada, Reno
Anxiety, Anxiety Disorders
In Vivo Exposure vs. Videochat-Based Vicarious Exposure
After screening (including parts of the Mini-DIPS), participants will receive a pre-assessment with a baseline heartrate measurement, self-report measures and two BATs (with the treated spider and the non-treated spider).
- Trial name
- NCT07432945
- Testing
- In Vivo Exposure Training (IVET), Vicarious Exposure Training (VicET)
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Ruhr University of Bochum
Specific Phobias
tDCS-Augmented Exposure Therapy for Pathological Fear
This double-blind randomized controlled clinical trial aims to test whether transcranial direct current stimulation (tDCS) can be used to modulate fear extinction learning during exposure therapy for pathological fear, including…
- Trial name
- NCT03095482
- Testing
- Transcranial Direct Current Stimulation (tDCS), In vivo exposure therapy
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Specific Phobia
Enhancing Exposure Therapy for Snake and Spider Phobias
This study tests whether exposure therapy for fear of snakes or spiders is enhanced by the addition of a brief fear retrieval trial prior to treatment, and the use of compound extinction during treatment.
- Trial name
- Snake/Spider (NCT02160470)
- Testing
- Exposure Therapy with Retrieval, Exposure Therapy with Compound Extinction, Exposure Therapy with Retrieval and Compound Extinction
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Phobia, Specific
Virtual Reality Immersive Method for Spider (Phobia) Exposure Therapy (VIMSE)
The aim of this study is to examine the efficacy of virtual reality exposure therapy as a treatment for specific phobia (spiders).
- Trial name
- VIMSE (NCT02533310)
- Testing
- OST treatment with in-vivo spiders, VR-OST treatment with virtual spiders
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Stockholm University
Fear of Spiders
Neural Mechanisms of Imaginal and in Vivo Exposure
Imaginal exposure is a widely used and effective psychological treatment technique. Recent research suggests that neural activations and emotional responses during imaginal exposure are similar to those elicited during in vivo…
- Trial name
- NCT05193383
- Testing
- Imaginal exposure, Exposure, Approach-avoidance conflict
- Where
- Sweden
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Spider Fear, Arachnophobia
Optimizing Exposure Using Occasional Aversive Imagery in Spider Fearful Individuals
The effectiveness of an optimized extinction training is investigated in spider-fearful individuals. Participants will undergo a one-session standardized extinction training, either with or without occasional metal imagination of…
- Trial name
- NCT05424250
- Testing
- occasional aversive imagination, Exposure
- Where
- Germany
- Volunteers
- 67 people
- Sponsor
- Philipps University Marburg
Specific Phobia, Animal
A Randomized Controlled Efficacy Trial of a Telemedicine-based Virtual Reality Clinic for the Treatment of Phobias
The goal of this clinical trial is to learn if a telemedicine-based virtual reality clinic (Doxy.me VR) works to treat dog, spider, and snake phobias in adults.
- Trial name
- NCT07558824
- Testing
- Telemedicine-Based Virtual Reality Exposure Therapy, Telemedicine-Based Exposure Therapy Using Photos and Videos
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of South Florida
Specific Phobia
The Effects of Safety Seeking Behaviors During Exposure Therapy for Adults With Spider Phobia
Exposure-based cognitive-behavioral therapy (i.e., "exposure therapy"), which entails repeated and prolonged confrontation with feared situations/stimuli, is the most effective treatment for anxiety disorders (e.g.…
- Trial name
- NCT03233113
- Testing
- Exposure therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Anxiety Disorders, Arachnophobia
Optimizing Exposure Therapy With Mental Rehearsal
Treatment response rates for cognitive behavioral therapy (CBT) across anxiety disorders average approximately 50% post-treatment (Loerinc et al, 2015), evidencing significant 'return of fear', the re-emergence of a partially or…
- Trial name
- NCT03934385
- Testing
- Mental Rehearsal, Exposure
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of California, Los Angeles