Clinical trials: Photobiomodulation Therapy
Radiodermatitis, Breast Cancer
Photobiomodulation Therapy for the Prevention of Acute Radiodermatitis in Breast Cancer Patients Undergoing Radiotherapy
Radiodermatitis (RD), an inflammatory skin reaction, occurs in more than 90 percent of cancer patients treated with radiotherapy (RT). This is the result of the radiation causing damage to the epidermal basal skin stem cells.
- Trial name
- LABRA (NCT03924011)
- Testing
- Photobiomodulation therapy (PBMT)
- Where
- 2 sites in Belgium
- Volunteers
- 71 people
- Sponsor
- Hasselt University
Neck Pain
Effect of Dose Variations of High-Power Laser Therapy on Patients With Nonspecific Cervical Pain
Nonspecific neck pain, defined as pain without a specific underlying pathology, is a common musculoskeletal disorder that affects a significant proportion of the global population.
- Trial name
- NCT07196800
- Testing
- High intensity laser therapy (low dose) combined with conventional physiotherapy program, High intensity laser therapy (High dose) combined with conventional physiotherapy program
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Deraya University
Injuries to the Nipple (Fissures and Cracks) Resulting Breastfeeding
Photobiomodulation as a New Approach for the Treatment of Nipple Traumas
Inadequate care during pregnancy and postpartum are predisposing factors for the emergence of nipple fissures. The therapeutic approach of nipple trauma care guidelines aimed at the breast and the appropriate techniques for…
- Trial name
- NCT01462019
- Testing
- Photobiomodulation
- Where
- Brazil
- Sponsor
- Pontifícia Universidade Católica de Minas Gerais
Dentin Hypersensitivity
Laser Therapy for Dentin Hypersensitivity
This split-mouth randomized controlled clinical trial compared the effectiveness of Er,Cr:YSGG laser irradiation, a hydroxyapatite- and fluoride-containing agent (Remin Pro), and their combined application in the treatment of…
- Trial name
- NCT07431736
- Testing
- Er,Cr;YSGG Laser, Waterlase, Biolase Technology Inc., Irvine, CA, ABD, Remin Pro (VOCO, Cuxhaven, Germany)
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Hacettepe University
Myofascial Pain Syndrome
New Generation Low Level Laser Effect in Myofacial Pain Syndrome
Low level laser treatments have been used to treat painful trigger points in myofascial pain syndrome (MPS), but the effectiveness of the appropriate laser type and parameters is still uncertain.
- Trial name
- NCT06442553
- Testing
- GRR laser, Nd:YAG laser
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Mild Cognitive Impairment (MCI), Mild Alzheimer Disease
Efficacy and Safety of Photobiomodulation Therapy in Patients With Mild Cognitive Impairment and Mild Alzheimer's Disease
The goal of this clinical trial is to learn if photobiomodulation therapy (PBMT) can help treat mild cognitive impairment and mild Alzheimer's disease in adults aged 50 to 85 years. It will also learn about the safety of PBMT.
- Conditions
- Mild Cognitive Impairment (MCI), Mild Alzheimer Disease, Dementia
- Trial name
- PBMT in MCI (NCT07835399)
- Testing
- Photobiomodulation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Jun Xu
Muscle; Fatigue, Heart, Skeletal Muscle Recovery
Low Level Laser Therapy in Muscle Fatigue and Muscle Recovery
Muscle fatigue and muscle recovery after exercise are recent areas of research involving Low Level Laser Therapy (LLLT) and many factors remain unknown, such as optimal doses, power and application parameters, mechanisms of…
- Trial name
- LLLT (NCT01844271)
- Testing
- Low Level Laser (LLL)
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- University of Nove de Julho
Soft Tissue Healing
Laser-assisted Pontic Site Soft Tissue Healing Prior to Fixed Partial Denture Rehabilitation
This randomized placebo-controlled clinical trial aimed to evaluate the effect of laser-assisted therapy on soft tissue healing at the pontic site prior to fixed partial denture rehabilitation.
- Trial name
- NCT07415434
- Testing
- GRR laser, Nd:YAG laser
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Muscle Weakness, Sports Performance
Light Therapy and Electrical Stimulation on Functional Performance in Volleyball Athletes
Background: Volleyball players constantly perform vertical jumps, the higher the height of the jump is better sports performance of these players. Several methods have been tested to improve jumping performance in these players.
- Trial name
- NCT02443701
- Testing
- Exercise, LASER, NMES
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centro de Traumatologia do Esporte
Dry Eye Syndromes, Meibomian Gland Dysfunction
Photobiomodulation With REd vs BluE Light (REBEL)
The use of photobiomodulation or low-level light therapy (LLLT) in the ophthalmic field stemmed from dermatology which has shown impact on skin blood flow and regeneration.
- Conditions
- Dry Eye Syndromes, Meibomian Gland Dysfunction, Blepharitis
- Trial name
- NCT06371300
- Testing
- Red LLLT, Blue LLLT
- Where
- 2 sites in New Zealand, United Kingdom
- Volunteers
- 36 people
- Sponsor
- Aston University
Low Back Pain
Efficacy Of Non-Invasive High Power Laser Acupuncture Stimulation In Chronic Non-Specific Low Back Pain
This study will be conducted to answer the following question: Does high power laser acupuncture has any effect on pain, back range of motion, function, quality of life, fatigue and level of satisfaction in chronic nonspecific…
- Trial name
- NCT05970419
- Testing
- high power laser acupuncture (HPLA), conventional treatment
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Myofascial Pain Syndrome - Neck, Extracorporeal Shockwave Therapy
rESWT vs LLLT for Cervical Myofascial Pain
Background and Aim: Myofascial pain syndrome (MPS) in the cervical region is one of the most common musculoskeletal disorders associated with myofascial trigger points that cause muscle pain, stiffness, and reduced range of…
- Conditions
- Myofascial Pain Syndrome - Neck, Extracorporeal Shockwave Therapy, Low-Level Light Therapy, Trigger Point Pain, Myofascial
- Trial name
- NCT07593781
- Testing
- Radial Extracorporeal Shockwave Therapy, Low-Level Laser Therapy
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Universitas Indonesia
Endometriosis, Dyspareunia
Transvaginal Low-level Laser Therapy to Improve Pelvic Pain and Sexual Function in Patients with Endometriosis.
Dyspareunia is defined as pain with penetrative sexual intercourse. Women with endometriosis have a nine-fold increased risk of dyspareunia, when compared to the general female population.
- Conditions
- Endometriosis, Dyspareunia, Pelvic Pain
- Trial name
- NCT05540353
- Testing
- Transvaginal photobiomodulation
- Where
- 6 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Parkinson Disease
Photobiomodulation and Parkinson
This study aimed to assess the effects of transcranial photobiomodulation in patients with Parkinson's disease (PD).
- Trial name
- NCT03811613
- Testing
- Transcranial photobiomodulation
- Where
- 2 sites in Spain
- Volunteers
- 35 people
- Sponsor
- University of Oviedo
Dentin Sensitivity
CPP-ACPF and Laser's Effect on Dentin Hypersensitivity
The aim of this study was to evaluate the effect of casein phosphopeptide amorphous calcium phosphate fluoride paste (CPP-ACPF) associated with low level laser therapy (LLLT) in the symptomatology and on the quality of life of…
- Trial name
- NCT03750851
- Testing
- CPPACPF, Laser, LaserCPPACPF
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Wound Healing Delayed
Microcurrent Therapy and Low-Level Laser Therapy on Wound Healing
The study aiming to compare between the Microcurrent and Low-Level Laser Therapy on wound healing
- Trial name
- NCT05326022
- Testing
- Microcurrent therapy, Low Level Laser Therapy, Medical therapy
- Volunteers
- 90 people
- Sponsor
- Nehad Ahmed Youness Abo-zaid
Low-grade Glioma, Recurrent Low Grade Glioma
Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma
This study aims to evaluate the efficacy of Laser Interstitial Thermal Therapy (LITT) in treating recurrent or progressive, low-grade gliomas (LGG) in pediatric, adolescent and young adult patients.
- Conditions
- Low-grade Glioma, Recurrent Low Grade Glioma, Low Grade Glioma of Brain, Pediatric Cancer
- Trial name
- NCT07506239
- Testing
- Laser Interstitial Thermal Therapy (LITT), Magnetic resonance imaging (MRI), Questionnaires
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
DENT IMPLANTS, LASER
Clinical and Microbiologic Outcomes of aPDT in the Non-surgical Treatment of Implant Inflammation
The purpose of this study is to compare clinical outcomes (change in bleeding sites (BOP) and probing depth reduction (PPD) after mechanical debridement of implant surfaces at sites exhibiting plaque induced inflammation with or…
- Trial name
- NCT04187053
- Testing
- Conventional mechanical therapy, Saline, Methylene Blue
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- The University of Texas Health Science Center, Houston
Laser and LED Therapy on Elderly Individuals With Temporomandibular Disorder
Effects of Laser Therapy and LED Therapy on Elderly Individuals With Temporomandibular Disorder
Temporomandibular disorder (TMD) is described as a subgroup of orofacial pain with a set of signs and symptoms that involve the temporomandibular joint, masticatory muscles, ears and neck.
- Trial name
- NCT03257748
- Testing
- Laser Therapy, LED therapy
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Circumferential Reduction, Waist Circumferential Reduction
BTL-9000 Low Level Laser Therapy for the Waist Circumferential Reduction
Prospective, two-arm, randomized study of the effectiveness of the BTL-9000 LLLT in achieving 3 cm or greater average waist circumferential reduction in LLLT group of subjects relative to the base line and 1 cm or greater…
- Trial name
- NCT02023385
- Testing
- BTL-9000 LLLT
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.