Clinical trials: Photodamage
Photodamaged Skin
Placebo-Controlled Study Assessing the Use of a Novel Exfoliative Serum With A Chemical Peel to Improve Photodamage in Adults
This is a split-face, double-blind, placebo-controlled study assessing the use of a novel exfoliative serum with a chemical peel to improve photodamage in healthy female subjects between the ages of 30 and 65 years, inclusive…
- Trial name
- NCT05908825
- Testing
- Vitamin C with AHA Exfoliative Serum
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Austin Institute for Clinical Research
Photodamage
Laser 360iQ: Optimal Light-laser Combination Therapy
To assess the safety and efficacy of light-laser combination therapy for the improvement of skin color, tone, texture and laxity
- Trial name
- NCT04519723
- Testing
- Assess the safety and efficacy of light-laser therapy using the Harmony XL and Dye-VL (500-600nm), Q-Switched 1064nm, Er:YAG 2940nm modules in combination .
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Alma Lasers Inc.
Photodamaged Skin, Photoaging
Altreno for Chest Rejuvenation
This is a single-center, prospective, double-blind, randomized, vehicle-controlled study to evaluate the efficacy, safety and patient satisfaction of tretinoin 0.05% lotion (Altreno) for chest rejuvenation.
- Trial name
- NCT04096742
- Testing
- tretinoin 0.05% lotion (Altreno), Vehicle
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Non-melanoma Skin Cancer
Dietary Prevention of Photodamage in Skin With Grapes
To assess the effect of orally administered grape powder on the sunburn reaction in humans.
- Trial name
- NCT02760160
- Testing
- Reconstituted grape powder
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Skin Manifestations
Tolerability and Efficacy of Anti-Aging Treatment Regimen in Subjects With Photodamage
The subjects will use the test skincare products. This is a full face, twice daily application study, with digital photos and expert grader evaluations at Baseline, 4 and 8 week periods.
- Trial name
- NCT02422836
- Testing
- Three Product Anti-Aging Treatment Regimen
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- US CosmeceuTechs, LLC
Skin Care
Study to Assess the Cosmetic Changes in the Facial Skin After Use of a Topical Retinoid Product in Participants With Moderate to Severe Photodamage
This study will assess the cosmetic changes of a cosmetic topical retinoid product in participants with moderate to severe photodamage utilizing non-invasive in vivo skin imaging instrumentation.
- Trial name
- NCT03302559
- Testing
- Retinol Complex 0.5, Facial cleanser, Moisturizing lotion
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Allergan
Anti-aging, Photoaging
A Twelve Week Clinical Study to Evaluate the Efficacy and Tolerability of a Sunscreen Moisturizer SPF 50+
The primary objective of this study is to evaluate the efficacy and tolerance of a moisturizer SPF 50+ when used over a 12-week time period by women with moderate to severe facial photodamage.
- Trial name
- NCT06148558
- Testing
- Sunscreen Moisturizer, Gentle Cleansing Lotion, Facial Moisturizer
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Photodamaged Skin
Effect of Topical Agents With Various Antioxidant Containts on Photodamage Skin Induced
Ultraviolet (UV) irradiation of the skin leads to acute inflammatory reactions such as erythema, sunburn, and chronic reactions, including premature skin aging and skin tumors.
- Trial name
- NCT06170346
- Testing
- Antioxidants, Vehicle
- Where
- Indonesia
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Photodamage, Photoaging
Efficacy and Safety of Oral Isotretinoin for Cutaneous Photodamage
This is a randomized, comparative, single evaluator-blinded trial to evaluate clinical, histological and immunohistochemical effects of oral isotretinoin plus moisturizer sunscreen as compared to the use of 0,05% tretinoin cream…
- Trial name
- NCT00842907
- Testing
- oral isotretinoin, Tretinoin
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Rosacea
EVALUATION OF THE EFFECT OF THE PERFECTA V-BEAM LASER ON ROSACEA
The purpose of this study is to further quantify the safety and effectiveness of the Syneron-Candela long pulse-duration, extended sub-pulse, larger spot-size prototype Perfecta V-Beam, 595nm laser system for the treatment of…
- Trial name
- NCT03211585
- Testing
- Perfecta V-Beam laser
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Skin Ageing, Skin
Skin Type Determination Using Image Artificial Intelligence
Skin color, how easily a person burns or tans in the sun (skin phototype), and the amount of chronic sun damage in the skin are important factors in skin health.
- Trial name
- SPAI (NCT07765303)
- Testing
- Skin imaging and skin characteristic assessment
- Where
- 13 sites in Australia, Brazil and 9 more
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Region Skane
Photodamage
Single Band vs. Dual Band Pulsed Light Technology for the Treatment of Photodamage - A Split Face Comparison Study
Both the Dye - VL 500 - 600 nm and the Dual band will improve significantly the appearance of Photo Damage with high efficacy including; safety, minimal discomfort and downtime.
- Trial name
- NCT04519736
- Testing
- Single Band vs. Dual Band Pulsed Light Technology for the Treatment of Photodamage
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alma Lasers Inc.
Photodamaged Skin
Study Comparing Two Serums With Intense Pulsed Light for the Treatment of Moderate to Severe Photodamage and Crepiness on the Forearms
The primary objective is to compare Re-Q Pro-Longevity serum versus vehicle serum combined with Intense Pulsed Laser for the treatment of moderate to severe photodamage and crepiness on the dorsal forearms.
- Trial name
- NCT07686198
- Testing
- Right Arm treated with Active Re-Q Pro-Longevity Serum and Intense Pulsed Light Therapy, Left Arm treated with vehicle serum and Intense Pulsed Light Therapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Photoaging, Photodamage
Randomised Controlled Trial of an Antioxidant and Sunscreen Combination Cream for Reducing DNA Damage in Human Skin
This randomized, double-blind, vehicle-controlled clinical trial investigates whether daily use of an encapsulated SPF 50 formulation containing a multi-antioxidant complex provides greater mitochondrial DNA (mtDNA) protection in…
- Conditions
- Photoaging, Photodamage, Mitochondrial Damage, Sunscreen
- Trial name
- NCT07301515
- Testing
- Antioxidant + Sunscreen Cream
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Klira Skin
Hyperpigmentation, Melasma
Annurca Apple Peel Oleolite for the Treatment of Skin Hyperpigmentation
The aim of this cosmetic clinical trial is to learn if an oleolite derived from Annurca Apple peel (AAO) works to enhance skin tone and luminosity, by counteracting the visibility of skin hyperpigmentation and dark spots in adult…
- Conditions
- Hyperpigmentation, Melasma, Skin Spots, Photodamaged Skin
- Trial name
- EAAO22G01 (NCT07040345)
- Testing
- Annurca apple oleolite
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ritamaria Di Lorenzo
Actinic Keratoses, Photodamage
Activation of Ameluz With BBL HEROic for the Treatment of Actinic Keratoses and Photodamage
To provide a treatment of both actinic keratoses and photodamage within one treatment.
- Trial name
- NCT07053852
- Testing
- Ameluz, Sciton HEROic
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sherrif Ibrahim
Wrinkle
Evaluating the Safety and Effectiveness of the Tixel Fractional System in the Treatment of Photodamage at Low Settings
To demonstrate the safety and performance of the Tixel fractional system for treatment of photodamage using low-energy settings.
- Trial name
- NCT05182502
- Testing
- Tixel
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Eric Bernstein, MD