Clinical trials: Photoplethysmography
Atrial Fibrillation (AF)
Smartphone Based-PPG Assessment of REconversion in Persistent Atrial Fibrillation
This study investigates whether a smartphone application that measures heart rhythm using light, a technique known as photoplethysmography or PPG, can accurately detect when the cardiac arrhythmia atrial fibrillation (AF)…
- Trial name
- SPARE-AF (NCT07752940)
- Testing
- Smartphone-based PPG monitoring
- Where
- 2 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Ziekenhuis Oost-Limburg
Atrial Fibrillation (AF), Heart Failure
A Photoplethysmography-Based Machine Learning Algorithm for Early Atrial Fibrillation Detection: A Prospective Validation Study
This is a prospective study validating a new machine-learning algorithm that detects atrial fibrillation (AF) from photoplethysmography (PPG) signals, developed for integration into the Seerlinq remote monitoring platform.
- Trial name
- HeartCore AF (NCT07749183)
- Testing
- PPG-based AF detection algorithm
- Where
- Slovakia
- Volunteers
- 200 people
- Sponsor
- Seerlinq s. r. o.
Hypertension, Heart Failure
Pulse Wave Parameters in the Assessment of Systolic Function of the Left Ventricle.
This is a prospective, single-center, non-randomized, observational study. The aim of this study is to determine the potential of a single-lead electrocardiogram monitor CardioQvark with photoplethysmography function use to…
- Trial name
- NCT04788342
- Testing
- pulse wave recording, echocardiography.
- Where
- Russia
- Volunteers
- 400 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Blood Pressure, Heart Disease
Accuracy of a Cuffless Photoplethysmography (PPG) Chest-Patch Monitor for 24-hour Ambulatory Blood Pressure Monitoring (ABPM)
This study aims to validate the accuracy and reliability of blood pressure (BP) estimates obtained over 24 hours using a PPG-based chest-patch device compared to the gold standard ambulatory blood pressure monitoring (ABPM)…
- Conditions
- Blood Pressure, Heart Disease, Hypertension (HTN), Blood Pressure Monitoring
- Trial name
- PPG ABPM (NCT07240831)
- Testing
- Model BB-613WP
- Where
- 11 sites in United States, Israel and 1 more
- Volunteers
- 612 people
- Sponsor
- Biobeat Technologies Ltd.
Plethysmography, Remote Photoplethysmography Imaging
Assessment of Physiological Parameters Measurements (Heart Rate, Respiratory Rate, and Oxygen Saturation) by Standard Acquisition System Compared Remote Photoplethysmography Imaging System l
Introduced in 1930, photoplethysmography techniques presented the possibility of measuring SpO2 and HR using the absorption of light by the blood to define these signals In recent years, a new approach to photoplethysmography to…
- Conditions
- Plethysmography, Remote Photoplethysmography Imaging, Physiological Parameters
- Trial name
- NCT04660318
- Testing
- Remote photoplethysmography for physiological parameters, standard acquisition system for physiological parameters
- Where
- France
- Volunteers
- 1,045 people
- Sponsor
- Central Hospital, Nancy, France
Atrial Fibrillation, Atrial Fibrillation Recurrent
DIGITal mOnitoring afTer Af abLation
Recurrence of atrial fibrillation (AF) after a pulmonary vein isolation (PVI) procedure is frequent. Current follow up with Holter monitoring and electrocardiograms (ECG) during outpatient clinic consultations cover only short…
- Conditions
- Atrial Fibrillation, Atrial Fibrillation Recurrent, PVI
- Trial name
- DIGITOTAL (NCT05486364)
- Testing
- Digital Monitoring, Standard of care
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Ziekenhuis Oost-Limburg
Hypertension, Target Organ Damage
GlycOxiTOD: Multimodal Vascular and Target-Organ Damage Registry
The goal of the GlycOxiTOD observational registry is to improve the early detection and characterization of vascular and other target-organ damage in adults at increased cardiovascular risk.
- Conditions
- Hypertension, Target Organ Damage, Heart Disease Risk Factors, Vascular Stiffness
- Trial name
- GlycOxiTOD (NCT06325800)
- Testing
- Multimodal Cardiovascular Phenotyping
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Complejo Hospitalario Universitario de Santiago
Arrhythmia
Hearables: Ear-ECG and PPG for Detection of Cardiac Arrhythmias
The goal of this observational study is to determine the feasibility of detecting abnormal heart rhythms, known as arrhythmias, by recording Electrocardiogram (ECG) and Photoplethysmogram (PPG) waveforms from the ears in patients…
- Trial name
- NCT06667258
- Testing
- Ear ECG/PPG sensors
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Labor Epidural Analgesia, Perfusion Index
Perfusion Index Variability During Epidural Labor Analgesia
This prospective, single-centre observational study evaluates changes in the peripheral Perfusion Index (PI) - a non-invasive parameter derived from the pulse-oximetry photoplethysmographic waveform - in women receiving epidural…
- Conditions
- Labor Epidural Analgesia, Perfusion Index, Pain
- Trial name
- NCT07831967
- Testing
- Epidural (or opioid-only combined spinal-epidural) labor analgesia
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Gdansk
Vascular Diseases
Photoplethysmography Detects Changes in Vascular Tone
Changes in the vascular tone of anesthetized patients is common and cause hemodynamic problems. The monitoring of such changes in vascular resistance using simple and non-invasive tools is lacking.
- Trial name
- NCT02854852
- Where
- Argentina
- Volunteers
- 50 people
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Vital Sign Evaluation
Clinical Validation of Non-Contact Vital Signs
Vital signs are critically important to modern emergency medical care. These metrics (heart rate (HR), respiratory rate (RR), blood pressure, temperature, and pulse oximetry) have been shown to predict a patient's morbidity…
- Trial name
- NCT07362641
- Testing
- SmartSpectra Vital Signs Monitor measurement
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Presage Technologies, Inc.
Diabetes Type 2
Effects of Different Doses of Aspirin on Pathophysiological Markers in Type 2 Diabetes
This study was set up to assess the effects of different doses of aspirin when compared with placebo (dummy drug), used sequentially over a 2 week study period with a 2 week wash-out (rest period) in between, in people with…
- Trial name
- NCT00898950
- Testing
- Aspirin
- Where
- 2 sites in United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Portsmouth
Acute Disease, Disease Progression
Multimodal Digital Biomarker Prediction of Acute Clinical Deterioration
Rather than relying on a single abnormal vital sign, the study will examine how multiple physiologic signals change together over time and whether changes in the relationships among these signals provide useful information about…
- Conditions
- Acute Disease, Disease Progression, Critical Illness, Biomarkers
- Trial name
- FUSION-72 (NCT07817550)
- Testing
- Multimodal Digital Biomarker Monitoring
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Truway Health, Inc.
Healthy Humans, Vital Signs Monitoring
Performance Assessment Study VitalSigns Camera
This Performance Assessment Study will focus on testing the performance of the VitalSigns Camera under various suboptimal use cases.
- Trial name
- NCT05465018
- Testing
- Happy Flow / Baseline, Make-up, Sunglasses
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Atrial Fibrillation (AF)
Photoplethysmography (PPG) Algorithm With Smartwatch in Evaluation of Atrial Fibrillation Burden
The purpose of this study is to evaluate the monitoring effect of a smart electrocardiogram watch based on the PPG algorithm on atrial fibrillation burden.
- Trial name
- Polaris-AF (NCT06686940)
- Testing
- intervention group
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Beijing Anzhen Hospital
Healthy, Hypertension
A Validation Study of Selfie Technology for Assessment of Vital Signs
The aim of this study is to compare accuracy of DocMe, a video technology developed by DocMe Health Technologies, with previously validated medical devices used for measurements of heart rate, heart rate variability, respiratory…
- Trial name
- NCT05117762
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- DocMe Technologies Ltd
Heart Failure With Reduced Ejection Fraction; Hypertension
Feasibility and Effectiveness of a Ring-Type Blood Pressure Device (CART-BP) Compared With 24-Hour Ambulatory Blood Pressure Monitoring in HFrEF
This study aims to evaluate the feasibility and diagnostic accuracy of the CART-BP ring-type wearable blood pressure monitoring device in comparison with 24-hour ambulatory blood pressure monitoring (ABPM) in patients with heart…
- Trial name
- RING-HFrEF (NCT07626879)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Keimyung University Dongsan Medical Center
Atrial Fibrillation, Arrhythmias, Cardiac
Apple Heart Study: Assessment of Wristwatch-Based Photoplethysmography to Identify Cardiac Arrhythmias
The Apple Heart Study (AHS) is a research study conducted to evaluate whether the Apple Heart Study App can use data collected on the Apple Watch to identify irregular heart rhythms, including those from potentially serious heart…
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Atrial Flutter
- Trial name
- NCT03335800
- Testing
- Apple Heart Study App
- Where
- United States
- Volunteers
- 419,927 people, healthy volunteers welcome
- Sponsor
- Apple Inc.
Atrial Fibrillation, Arrythmia, Cardiac
Validation Study of the Watch HWA09 and Its Softwares ECG-SW1 and PPG-SW1 for the Detection of Atrial Fibrillation
The proposed clinical study aims to validate the diagnostic performance, compared to a reference ECG, of the ECG-SW1 software and the PPG-SW1 software integrated into the HWA09 watch developed by Withings for the automatic…
- Trial name
- WEFA (NCT04351386)
- Testing
- AF Detection
- Where
- 3 sites in France
- Volunteers
- 283 people
- Sponsor
- Withings
Hypovolemia
Detection of Hypovolemia Using Pleth Variability Index (PVI)
The purpose with the planned study is to study Pleth Variability Index (PVI) as a non invasive indicator for mild hypovolemia during spontaneous breathing in healthy subjects.
- Trial name
- NCT01456559
- Testing
- Lower body negative pressure (LBNP)
- Where
- 2 sites in Sweden
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping