Clinical trials: Photosensitivity
Sunburn
Randomized Trial of a Sun Safety Intervention for Young Adults
The goal of this randomized controlled trial is to test the efficacy of a dissonance induction intervention compared to a control group on tanning in 278 young adult tanners. The primary outcome will be tanning at 3-months.
- Trial name
- NCT07751406
- Testing
- Healthy Skin, Healthy Lifestyle
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Cannabis Use, Sleep
Cannabis Effects on Sleep, Circadian Rhythms, and Light Sensitivity in Young Adults
The goal of this study is to learn how cannabis use and discontinuation affect sleep, circadian rhythms, and sensitivity to light. The main questions it aims to answer are: 1.
- Conditions
- Cannabis Use, Sleep, Circadian Rhythm
- Trial name
- CASCILS (NCT06743373)
- Testing
- Cannabis Discontinuation
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Phototoxicity
Phototoxicity of Frequently Prescribed Medicines
This pilot trial aims to study 10 selected commonly prescribed medicines with different grade of phototoxic potential. As there is no currently established way to assess phototoxic potential in a systematic and quantitative way…
- Trial name
- Phototox (NCT06710600)
- Testing
- Single oral dose of selected medicines, respectively, UVA and UVB radiation
- Where
- Austria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Healthy
Evaluation of Photosafety of BI 730357 Compared to Placebo and the Known Photosensitizing Agent Ciprofloxacin
To evaluate the photosensitivity potential of BI 730357
- Trial name
- NCT04147260
- Testing
- BI 730357, Ciprofloxacin
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Photoallergy
Evaluation of Potential Development of Photoallergic Skin Reaction After Use of MC2-01 Cream
This trial is a 6-week, Randomized study evaluating the potential of MC2-01 Cream to induce a photoallergic skin reaction in Healthy subjects, using a controlled photopatch test design.
- Trial name
- NCT03899064
- Testing
- Induction: Application of MC2-01 Cream, irradiation, Induction: Application of MC2-01 Cream, no irradiation, Induction: Applications of MC2-01 vehicle, irradiation
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- MC2 Therapeutics
Skin Ageing, Skin
Skin Type Determination Using Image Artificial Intelligence
Skin color, how easily a person burns or tans in the sun (skin phototype), and the amount of chronic sun damage in the skin are important factors in skin health.
- Trial name
- SPAI (NCT07765303)
- Testing
- Skin imaging and skin characteristic assessment
- Where
- 13 sites in Australia, Brazil and 9 more
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Region Skane
Acne Vulgaris
A Study to Evaluate the Potential of Tazarotene Foam to Cause a Reaction When Applied to the Skin and Exposed to Light on Healthy Volunteers
The purpose of this study is to evaluate the potential of Tazarotene Foam to induce a phototoxic reaction when exposed to UV and VIS light on skin of healthy volunteers.
- Trial name
- NCT01115322
- Testing
- Tazarotene Foam without irradiation, Tazarotene Foam with UVA and UVB irradiation, Tazarotene Foam with UVA, UVB, and visible light
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Hyperalgesia
The Effect of Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers
Treatment of chronic pain is a major clinical challenge since chronic pain is frequent and leads to deterioration of quality of life.
- Trial name
- RemiSun 1 (NCT00811837)
- Testing
- Midazolam, Remifentanil
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Sensitivity, Contact, Photosensitivity
Dermatological Assessment of Primary Dermal Irritability Accumulated, Sensitization, Photoallergy and Photosensitization of a Scar Gel
Evaluate the potential of Primary Dermal Irritability, Accumulated Dermal Irritability, Dermal Sensitization, Photoallergy and Photosensitization, of health products through the application of Patch Test, proving the safety of…
- Conditions
- Sensitivity, Contact, Photosensitivity, Phototoxicity
- Trial name
- NCT06723340
- Testing
- Scar gel
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Sunburn
The Sun Protective Effect of Melatonin
The aim of this study is to investigate the sun protective effect of melatonin, when used as a cream applied before sun exposure. Sun exposure induces erythema as indication of an inflammatory reaction in the skin.
- Trial name
- NCT01873430
- Testing
- Melatonin
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Skin Cancer
Photosensitivity of the Skin Under Azathioprin in Renal Transplant Recipients
Photosensitivity of the skin to UVA and UVB will be determined
- Trial name
- NCT00492895
- Testing
- Discontinuation of Azathioprin
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Sunburn
Dermal Irritation, Sensitization and Cumulative Irritation Potential of 6% Bemotrizinol
The purpose of this clinical trial is to evaluate the dermal safety of Bemotrizinol (6%).
- Trial name
- NCT05260359
- Testing
- 6% Bemotrizinol (BEMT) in a basic sunscreen oil formulation, 6% Bemotrizinol (BEMT) dispersion in petrolatum, Sunscreen oil vehicle with 10% ethanol as penetration enhancer without BEMT
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Sunburn, Erythema, Sun Protection
UV Exposure Assessed With Wearable Sensor and Sun Protection
The goal is to prevent ultraviolet light (UV) overexposure by providing consumers with relevant, easy-to-access, specifically actionable information.
- Trial name
- NCT03344796
- Testing
- Goal attainment
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Purpura, Thrombocytopaenic, Idiopathic
Study In Healthy Subjects To Evaluate The Photo-Irritant Potential Of Eltrombopag
This study is designed to investigate the safety profile and the photoirritant potential of eltrombopag in healthy subjects. The study is placebo- and positive controlled, randomized, parallel group with three treatment arms…
- Trial name
- NCT00688272
- Testing
- Ciprofloxacin, Eltrombopag
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Photosensitivity Disorders
Conventional Microneedling vs Microneedling With 5-FU (MMP) for Idiopathic Guttate Hypomelanosis (IGH) Repigmentation
The purpose of this study is to determine whether 5-FU infusion (Microinfusion of Medicine Percutaneously - MMP) is effective for Idiopathic Guttate Hypomelanosis (IGH) repigmentation compared to conventional Microneedling.
- Trial name
- MMP (NCT02904564)
- Testing
- MMP with 5-FU, MMP with Saline infusion
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Clinica Dermatologica Arbache ltda
Sunburn, Sun Damaged Skin
Natural Sunlight Protection and Simulated Sunlight Protection Offered by Sunscreens and Fabrics
The purpose of this study is to assess how human skin reacts and how sunscreens and sun protection fabrics protect in natural sunlight compared to their labeled claims, indoor testing methods (existing or modified) and…
- Conditions
- Sunburn, Sun Damaged Skin, Overexposure to Sun Rays
- Trial name
- NCT03007589
- Testing
- otc sunscreens, sun protection fabrics, Optical Filters
- Where
- 5 sites in United States, Chile and 1 more
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Protection Foundation
Hepatitis C Virus
TMC435-TiDP16-C125 - Study in Healthy Volunteers to Evaluate the Potential of TMC435 to Increase the Sensitivity of the Skin Towards Exposure to Sun Light
The purpose of the study is to evaluate the potential effect of TMC435 on the sensitivity of the skin towards exposure to sunlight.
- Trial name
- NCT01124799
- Testing
- TMC435, Ciprofloxacin
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Tibotec Pharmaceuticals, Ireland
Photosensitivity
The Role of Spectral Filtering in a Spectrally Adjustable Ocular Photosensitivity Analyzer
This is a 6-visit, single-center, non-dispensing, randomized, single-masked, 5×5 crossover study. Subjects will participate in 6 scheduled over the duration of approximately 10.5 months.
- Trial name
- NCT04811079
- Testing
- 419 nm Spectacle Filter, 437 nm Spectacle Filter, 456 nm Spectacle Filter
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Sun Sensitivity, Sun Protection
Helping Children be Safe Outdoors With Sun Protection
Childhood exposure to high levels of sunlight is a strong determinant of melanoma risk. Pediatric clinicians can provide important sun protection counseling.
- Conditions
- Sun Sensitivity, Sun Protection, Skin Cancer
- Trial name
- NCT02177006
- Testing
- Sun Protection Program
- Where
- United States
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Dermatitis, Photoallergic
Study to Find Out if Cream V61-044 Used to Treat Fungal Infections Causes an Allergic Skin Reaction to Sunlight in Healthy Participants
Allergic skin reaction can be produced by the combination of a chemical product applied to the skin and ultraviolet (UV) radiation (a type of invisible light that comes from the sun and other light sources and can hurt your skin…
- Trial name
- NCT04532164
- Testing
- Butenafine HCl 1% (BAY1896425) - Induction Phase, Butenafine HCl 1% (BAY1896425) - Challenge Phase
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Bayer