Clinical trials: Photosensitizing Agents
Sunscreening Agents
18348-Human Phototoxicity Test
To determine the phototoxic potential of a topically applied article in human subjects
- Trial name
- NCT02823483
- Testing
- Sunscreen Lotion (BAY987521), Untreated Skin
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy
Evaluation of Photosafety of BI 730357 Compared to Placebo and the Known Photosensitizing Agent Ciprofloxacin
To evaluate the photosensitivity potential of BI 730357
- Trial name
- NCT04147260
- Testing
- BI 730357, Ciprofloxacin
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Sunscreening Agents
Human Phototoxicity Test
To determine the phototoxic potential of a topically applied article in human subjects.
- Trial name
- NCT02754102
- Testing
- Sunscreen Spray- Liquid (BAY987516)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bayer
Chronic Periodontitis
PDT As An Adjunct To SRP In The Management of Chronic Periodontitis
The present study aims to evaluate photodynamic therapy (PDT) using Zinc oxide as a photosensitizer as an adjunct to scaling and root planing (SRP) in the management of chronic periodontitis.
- Trial name
- NCT03770819
- Testing
- Photodynamic therapy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- KLE Society's Institute of Dental Sciences
Peri-Implantitis
ICG-PDT, Periimplantitis, Diabetes Mellitus
In this study, the effect of photodynamic therapy (indocyanine green mediated) on the clinical, biological and inflammatory aspects was assessed in diabetic patients having peri-implantitis
- Trial name
- NCT04833569
- Testing
- ICG-PDT, peri-implant mechanical debridement
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Saud University
Periodontal Diseases, Chronic Periodontitis
Photodynamic Therapy During Supportive Periodontal Therapy
27 subjects on SPT, each with at least two residual pockets ≥5mm, were recruited for this randomised, split-mouth controlled trial, providing a total of 72 sites.
- Conditions
- Periodontal Diseases, Chronic Periodontitis, Periodontal Attachment Loss
- Trial name
- NCT02666573
- Testing
- Fotosan 630, CMS Dental, Copenhagen, Denmark, Scaling and root planing
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Sunscreening Agents
18794 - Human Photo Toxicity Test
To determine the phototoxic potential of a topically applied article in human subjects.
- Trial name
- NCT02751372
- Testing
- BAY 987517, Untreated Skin
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bayer
Actinic Keratosis, Natural Daylight Photodynamic Therapy
Daylight PDT for Actinic Keratoses: a Multicentre Study Comparing Two Photosensitizers (BF-200 ALA Versus MAL)
This study compares two photosensitizing creams' BF-200 ALA's (aminolevulinic acid, Ameluz®) and MAL's (methyl 5-aminolevulinate, Metvix®) efficacy on actinic keratoses in natural daylight photodynamic therapy (NDL-PDT).
- Trial name
- NCT02464709
- Testing
- Aminolevulinic Acid, Methyl 5-aminolevulinate
- Where
- 3 sites in Finland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Sunscreening Agents
Human Phototoxicity Test (823/2016)
To determine the phototoxic potential of a topically applied article in human subjects
- Trial name
- NCT02962856
- Testing
- BAY987517, Untreated Skin
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Bayer
Chronic Periodontitis
Evaluation of Antimicrobial Photodynamic Therapy as an Adjunct to Periodontal Treatment in Smokers
The study proposes to assess the effect of multiple applications of antimicrobial Photodynamic Therapy (aPDT) as an adjunct to non-surgical periodontal treatment (nsPT) in smokers without use of antibiotics.
- Trial name
- NCT03039244
- Testing
- Photodynamic therapy, Control Group, Diode Laser
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Sunscreening Agents
Human Phototoxicity Test
To determine the phototoxic potential of a topically applied article in human subjects
- Trial name
- NCT02751489
- Testing
- Bain De Soliel - Solid
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bayer
Periapical Diseases, Postoperative Dental Pain
Postoperative Pain in Photodynamic Therapy Using Curcumin As a Photosensitizer
In endodontics, various irrigation solutions are used to achieve antibacterial efficacy within the root canal. The antibacterial effect of curcumin-containing root canal solutions, when combined with photodynamic therapy, has…
- Conditions
- Periapical Diseases, Postoperative Dental Pain, Irrigation Solution, Photodynamic Therapy (PDT)
- Trial name
- NCT06752655
- Testing
- Curcumin with photodynamic thearpy, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Sunscreening Agents
Human Phototoxicity Test
To determine the phototoxic potential of a topically applied article in human subjects
- Trial name
- NCT02750475
- Testing
- Sunscreen Sport Lotion (BAY987516), Untreated Skin
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bayer
Periodontitis, Alveolar Bone Loss
Novel Photosensitizer in The Treatment of Chronic Periodontitis
The aim of this study is to evaluate the periodontal outcomes after applying antimicrobial photodynamic therapy with a novel photosensitizer as compared to LASER assisted scaling and root planing alone.
- Trial name
- NCT04374383
- Testing
- Phthalocyanine Dye, LASER assisted SRP
- Where
- 2 sites in India
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Sunscreening Agents
Human Phototoxicity Test
To determine the phototoxic potential of a topically applied article in human subjects.
- Trial name
- NCT02751541
- Testing
- Sunscreen Sport Spray (BAY987519), Untreated Skin
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bayer
Sunscreen Agents
Test the Phototoxicity of Sunscreen Products
The primary objective of this study was to evaluate the potential for phototoxicity of the sun care products SPF 50 Y65 110, SPF 50 Y51 002, and SPF 15 V27 104 compared to that of a negative control (0.9% sodium chloride [NaCl])…
- Trial name
- NCT02802930
- Testing
- SPF 50 Y65 110 (BAY987519), SPF 50 Y51 002 (BAY987519), SPF 15 V27 104 (BAY987519)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bayer
Periodontitis, Periodontal Inflammation
Indocyanine-green Mediated Photosensitizer VS Aloe Vera Gel: Adjunct Therapy to Scaling and Root Planing in Patients With Chronic Periodontitis
For proving the potential of tropical medicaments on clinical parameters of periodontitis, a comprehensive assessment is required between therapeutic medicaments.
- Trial name
- NCT04964167
- Testing
- Plant extract
- Where
- 2 sites in Pakistan, Saudi Arabia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Periodontal Diseases, Periodontal Pocket
Photodynamic in Periodontal Treatment
Dental biofilm is a primary etiological factor for periodontal diseases.(1) The bacterial biofilm would induce recruitment of leucocytes, neutrophils, and T lymphocytes and the secretion of antibodies, lipopolysaccharides, and…
- Trial name
- NCT05162417
- Testing
- Methylene Blue, Toluidine Blue O
- Where
- Iraq
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Sulaimani