Clinical trials: Physical Activity
Non-Small Cell Lung Cancer (NSCLC)
Digital Lifestyle Intervention for Lung Cancer Survivors
The aim of this study is to assess the efficacy of a digital lifestyle intervention in non-small cell lung cancer (NSCLC) survivors on health-related quality of life (HRQoL) over three months.
- Trial name
- QUALUCA (NCT05819346)
- Testing
- Lifestyle
- Where
- 4 sites in Switzerland
- Volunteers
- 21 people
- Sponsor
- Kai-Uwe Schmitt, PhD, MEng, ICID
Rheumatoid Arthritis
Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis
Rheumatoid Arthritis (RA) is a chronic inflammatory disease causing pain, stiffness, swelling and loss of joint function. This study will assess how safe and effective upadacitinib is in treating RA when compared to adalimumab in…
- Trial name
- SELECT- SWITCH (NCT05814627)
- Testing
- Upadacitinib, Adalimumab
- Where
- 218 sites in United States, Argentina and 23 more
- Volunteers
- 487 people
- Sponsor
- AbbVie
Cancer
Pre-infusion Aerobic Cycling Exercise for CardioRespiratory Fitness in Cancer Patients
Background to this Research Patients who undergo cancer treatment involving chemotherapy or immunotherapy, can experience considerable reductions in their fitness levels.
- Trial name
- PACE-CRC (NCT07182773)
- Testing
- Exercise
- Where
- Ireland
- Volunteers
- 80 people
- Sponsor
- University of Dublin, Trinity College
Stroke, Acute
Trunk Rotation And Lateral Flexion Exercises In Stroke Patients
In this study we want to introduce the beneficiary combine effects of chest mobilization and chest physiotherapy exercises by using cough peak flow meter and chest expansion in stroke patients.
- Trial name
- NCT06379854
- Testing
- chest physiotherapy, trunk rotation exercises,deep diaphragmatic also chest physiotherapy
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Non-small Cell Lung Cancer
Volrustomig Priming Regimens Exploratory Phase II Platform Study
Purpose of this study is to assess the safety, tolerability, pharmacokinetics, immunogenicity, and antitumor activity of volrustomig in combination with other anticancer drugs in participants with specified solid tumors.
- Trial name
- eVOLVE-01 (NCT06448754)
- Testing
- Volrustomig, Carboplatin, Pemetrexed
- Where
- 63 sites in United States, China and 12 more
- Volunteers
- 194 people
- Sponsor
- AstraZeneca
Osteoarthritis
Yoga as an Intervention for Women With Knee Osteoarthritis
Keeping individuals with knee osteoarthritis physically active is critically important. Exercise is effective at reducing pain while improving physical function.
- Trial name
- NCT02146105
- Testing
- Yoga For Knee Osteoarthritis
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- McMaster University
Nutrition, Physical Activity
Determination of Physical Activity Status and Adherence to the Mediterranean Diet in Adults and Related Health Outcomes
A physically active life with adequate and balanced nutrition is essential for a healthy life. Unhealthy diet and being physically inactive are among the common risk factors that need to be corrected in order to maintain and…
- Conditions
- Nutrition, Physical Activity, Chronic Disease, Obesity
- Trial name
- NCT05001256
- Testing
- questionnaire study
- Where
- Turkey (Türkiye)
- Volunteers
- 380 people
- Sponsor
- University of Gaziantep
Bone Cancer, Tumor
The Effects of Observer Presence and Type on Patients' Perception of Exercise After Bone Tumor Resection-A Qualitative Study
The primary aim of the study is to investigate the effects of supervised exercise, telerehabilitation and home-based exercise on patient perception in patients who have undergone bone tumor resection.
- Trial name
- NCT05397522
- Testing
- Supervised Exercise by a physiotherapist via face to face, Supervised Exercise by a physiotherapist via video conference
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Medeniyet University
Musculoskeletal Injury, Muscle Weakness
The ADAPTation to Therapeutic Resistance Training (ADAPT) Study
In 2018, the Academic Department of Military Rehabilitation (ADMR) published a pilot randomised controlled trial (RCT), demonstrating the feasibility and acceptability of integrating twice-daily blood flow restriction (BFR)…
- Trial name
- NCT05719922
- Testing
- Resistance Training
- Where
- 6 sites in United Kingdom
- Volunteers
- 150 people
- Sponsor
- Defence Medical Rehabilitation Centre, UK
Locally Advanced/Metastatic Solid Tumors
First-in-Human, Phase I, Open-label, Multicenter, Dose Escalation Clinical Study
First-in-Human, Phase I, open-label, multicenter, dose-escalation study to evaluate the safety, tolerability, PK, pharmacodynamics, and preliminary antitumor activity of FL115 in patients with advanced solid tumors who have…
- Trial name
- NCT06130722
- Testing
- FL115
- Where
- 3 sites in United States
- Volunteers
- 18 people
- Sponsor
- Suzhou Forlong Biotechnology Co., Ltd
Solid Tumor, Pancreatic Ductal Adenocarcinoma (PDAC)
Study of JYP0015 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
Evaluate the safety and antitumor activity of JYP0015 in adults with specific RAS mutant advanced solid tumors.
- Conditions
- Solid Tumor, Pancreatic Ductal Adenocarcinoma (PDAC), Non-small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC)
- Trial name
- STAR (NCT06895031)
- Testing
- JYP0015
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Guangzhou JOYO Pharma Co., Ltd
Healthy (For Part A), Chronic Myeloid Leukemia (for Part B and C)
Safety and Anti-leukemic Activity of Vodobatinib (K0706) for Treatment of Ph+ CML Resistant/Intolerant to ≥3 Prior CML Therapies
Phase 1/2 study to determine safety, tolerability, pharmacokinetics, and anti-leukemic activity of Vodobatinib (K0706) in treatment-refractory/intolerant CML
- Trial name
- NCT02629692
- Testing
- Vodobatinib (K0706) capsules
- Where
- 35 sites in United States, Belgium and 8 more
- Volunteers
- 124 people
- Sponsor
- Sun Pharma Advanced Research Company Limited
Knee Osteoarthritis
FAldini Sport Total Joint Arthroplasty-Knee II
The majority of patients undergoing total knee arthroplasty are elderly individuals with low functional demands, aiming to alleviate pain.
- Trial name
- FAST-K II (NCT06383936)
- Testing
- intensive rehabilitation after uncemented TKA
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
Pediatric Cancer
Physical Activity in Pediatric Cancer (PAPEC)
The aim of this randomized controlled trial on Physical Activity and Pediatric Cancer (PAPEC) is to assess the impact of an exercise program intervention in pediatric cancer patients undergoing chemotherapy for solid tumors.
- Trial name
- PAPEC (NCT01645436)
- Testing
- exercise training
- Where
- Spain
- Volunteers
- 49 people
- Sponsor
- Universidad Europea de Madrid
Stroke
Effect of Cerebellar Fastigial Nucleus Stimulation Combined With Sling Exercise on Motor Function in Hemiplegic Stroke Patients
This study aims to investigate the rehabilitative effects and synergistic potential of combining Fastigial Nucleus Stimulation (FNS) with Sling Exercise Training (SET) on motor function in patients with post-stroke hemiplegia.
- Trial name
- NCT07670936
- Testing
- Cerebellar Fastigial Nucleus Electrical Stimulation, Sling Exercise Therapy
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Shengjing Hospital
Non-specific Chronic Low Back Pain
Pelvic Floor Exercises Versus Swiss Ball Exercises in Patients With Non-Specific Chronic Low Back Pain
This randomized controlled trial aims to compare the effectiveness of pelvic floor muscle exercises and swiss ball exercises in females with non-specific chronic low back pain.
- Trial name
- NCT07610044
- Testing
- Baseline Physiotherapy, Swiss Ball Exercises, Pelvic Floor Muscle Exercises
- Where
- Pakistan
- Volunteers
- 69 people
- Sponsor
- University of Lahore
Low Back Pain, Mechanical, Symptoms and Signs
Validity and Reliability of the Turkish Version of the Low Back Activity Confidence Scale (Lobacs)
Patients will be recruited from the Outpatient Department of Physical Medicine and Rehabilitation, Kestel State Hospital, who have been diagnosed with mechanical LBP for the past 3 weeks (physical examination, neurological…
- Trial name
- NCT05927909
- Testing
- Low Back Activity Confidence Scale (Lobacs)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bursa City Hospital
Psychotic Disorders, Affective Disorder
Physical Activity, Psychopathology, and Quality of Life in People With Psychotic or Affective Disorders
This longitudinal observational study tests the associations between physical activity, health-related quality of life, and psychopathology symptoms among people diagnosed with schizophrenia or diagnosed with affective disorders.
- Trial name
- NCT05869409
- Testing
- Physical activity and sedentary behavior education
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Murmur, Heart, Rhythm; Abnormal
Evaluation of Cardiags Trimod for Analysis of Cardiac Activity
The current study concerns Cardiags Trimod, a new non-invasive medical device for cardiac examinations. The evaluation of its effectiveness is done relative to specific standard devices.
- Trial name
- EVALTRIMOD (NCT05162599)
- Testing
- Diagnostic study, experimental evaluative cross-sectional study
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- CARDIAGS
Dizziness, Equilibrium; Disorder, Labyrinth
Posturography-assisted Vestibular Retraining for Stable Unilateral Vestibular Deficit
People that have difficulty with balance have a higher risk of falling and reduced quality of life. Some individuals can learn to compensate using their vision, their sense of where their limbs are in space, and balance organs…
- Conditions
- Dizziness, Equilibrium; Disorder, Labyrinth, Inner Ear Injury, Inner Ear Disease
- Trial name
- NCT05115032
- Testing
- Vestibular retraining with dynamic posturography, At-home rehabilitation exercises
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- Eytan A. David
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