Clinical trials: Physical Activity
Obesity
Effect of High-intensity Intermittent Sprinting on Appetite Control on Obese Volunteers
Several studies have shown that high intensity intermittent sprints (HIIS) are more effective than moderate intensity continuous cycling (MICC) in reducing fat mass and improving insulin resistance in normal weight individuals.
- Trial name
- NCT01143363
- Testing
- resting - control, Moderate intensity exercise, High intensity intermittent training
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Unresectable Locally Advanced Cancer, Metastatic Pancreatic Cancer
Evaluation of an Adapted Physical Activity Program in Patients With Unresectable Pancreatic Cancer
Adapted Physical Activity (APA) program may provide an opportunity to improve symptoms for patients with unresectable pancreatic cancer.
- Trial name
- NCT02184663
- Testing
- without APA program, APA program
- Where
- 17 sites in France
- Volunteers
- 313 people
- Sponsor
- GERCOR - Multidisciplinary Oncology Cooperative Group
Physical Activity, Behavior
WalkIT Arizona: Walking Interventions Through Texting
The purpose of this study is to develop adaptive (AI) and micro-incentive (MI) interventions and test them against static (SI) and delayed-incentive (DI) interventions in a 4-arm randomized factorial trial to increase MVPA…
- Conditions
- Physical Activity, Behavior, Goals
- Trial name
- NCT02717663
- Testing
- Adaptive Goals, Static Goals, Delayed (non-contingent) Incentives
- Where
- United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Hypertension
Treating Hypertension With Breath Control
The purpose of this study is to determine if blood pressure can be reduced in hypertensive subjects by regularising and slowing their breathing. This may be a safe and affordable complementary treatment for hypertension.
- Trial name
- NCT01285193
- Testing
- Breath control
- Where
- Malaysia
- Volunteers
- 84 people
- Sponsor
- Penang Hospital, Malaysia
Epilepsy
The Effect of Anti-epileptic Drugs on Mitochondrial Activity
This study is based on the hypothesis that antiepileptic drugs (other than Valproic acid) have an effect on the mitochondrial oxidative phosphorylation.
- Trial name
- NCT01218321
- Testing
- antiepileptic treatment
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Hadassah Medical Organization
Thermoregulation, Sleep Disturbance
Acute Sleep Deprivation on Whole-body Heat Exchange During Exercise-heat Stress in Young and Older Men
Sleep deprivation has long been thought to modulate thermoregulatory function. Seminal work on sleep deprivation and thermoregulation has demonstrated that sleep-deprived individuals experience greater elevations in core…
- Conditions
- Thermoregulation, Sleep Disturbance, Heat Exchange, Aging
- Trial name
- NCT05838014
- Testing
- Sleep deprivation, Normal sleep
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Sedentary Behavior
A Culturally Adapted, Social Support-Based, Physical Activity Interventions for South Asian Indian Women in the United States
The purpose of this study is to assess the feasibility and acceptability of a peer-based dyadic social support health coaching physical activity (PA) intervention in inactive South Asian Indian (SAI) and to explore preliminary…
- Trial name
- NCT05966506
- Testing
- Dyad-based Zoom health coaching, Fitbit activity monitor, Electronic newsletters
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Primary Sjögren's Syndrome (pSS)
New Clinical End-points in Patients With Primary Sjögren's Syndrome
There are no approved treatments for pSS and the clinical endpoints currently used in clinical trials are inadequate to capture all aspects of the disease that should be evaluated in clinical trials.
- Trial name
- NECESSITY (NCT05113004)
- Testing
- Hydroxychloroquine 400mg/d, Leflunomide 20mg/d, Mycophenolate mofetil 2000mg/d
- Where
- 7 sites in France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Exergaming, Metabolic Syndrome
Immersive Virtual Reality Exergames and Office Workers' Cardiometabolic Health
The worldwide increasing of prevalence of non-communicable diseases has grown the recognition of necessity for identifying the modifiable risk in preventing and managing these diseases.
- Trial name
- NCT06556784
- Testing
- 12-week at-home immersive virtual reality exergame
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Guangzhou University
Multiple Myeloma
PF-06863135 As Single Agent And In Combination With Immunomodulatory Agents In Relapse/Refractory Multiple Myeloma
To assess the safety and tolerability at increasing dose levels of PF-06863135 in patients with relapse/ refractory multiple myeloma in order to determine the maximum tolerated dose and select the recommended Phase 2 dose.
- Trial name
- NCT03269136
- Testing
- PF-06863135 monotherapy IV or SC, PF-06863135 + dexamethasone, PF-06863135 + lenalidomide
- Where
- 37 sites in United States, Canada
- Volunteers
- 101 people
- Sponsor
- Pfizer
Coronavirus, Fatigue
Efficacy of an Asynchronous Telerehabilitation Programme in Post-COVID-19 Patient
SARS-CoV-2 is the coronavirus responsible for developing the disease known as COVID-19. Its evolution can range from an asymptomatic course, to rapidly evolve and cause an acute respiratory syndrome.
- Conditions
- Coronavirus, Fatigue, Musculoskeletal Complication
- Trial name
- NCT04794036
- Testing
- Asynchronous telerehabilitation programme, Rehabilitation programme
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- Universidad San Jorge
Child Obesity
More Outside Your Door: a Diet/physical Activity Intervention to Decrease Risk of Obesity in Alaska Native Preschoolers
The preschool age is a crucial period of growth and an optimal time to begin to establish healthy eating and physical activity habits leading to better food and activity choices into adulthood, thereby minimizing risk for…
- Trial name
- MOYD (NCT06303544)
- Testing
- Wedge 1
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Alaska Native Tribal Health Consortium
Effect of Progressive Relaxation Exercise
Progressive Relaxation Exercise on Pain, Anxiety and Patient Satisfaction
This single-center, prospective, randomized controlled trial was completed with a total of 70 patients, 35 in each of the intervention and control groups.
- Trial name
- NCT06871332
- Testing
- Progressive relaxation exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- TC Erciyes University
Obesity, Diabetes Mellitus
Incentivizing Lifestyle Modification to Reduce Disease Burden
Specifically, the main objective of this pilot and feasibility study is to develop the infrastructure that will be used in a larger study that would be proposed at a later date. Hence, this study has two parts.
- Trial name
- NCT02945332
- Testing
- Required supervised walking, Non-required supervised walking, Fitbit Flex
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Congenital Heart Defects, Inherited Cardiac Arrhythmias
Healthy Lifestyles for Children With Complex Heart Problems
Healthy Lifestyles for Children with Complex Heart Problems is a planning and resource development project. The goal of the project is to develop an implementation plan that would enable children with complex heart problems to…
- Conditions
- Congenital Heart Defects, Inherited Cardiac Arrhythmias, Cardiomyopathy
- Trial name
- ReACH (NCT01785498)
- Testing
- Supplementary resources
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Children's Hospital of Eastern Ontario
Stroke Sequelae
Sedentarism of Stroke Survivors in the Valencian Community and Development of a Self-management Program
Stroke is the third leading cause of disability worldwide. Women present a higher incidence of this pathology and prevalence of its risk factors.
- Trial name
- SEDMA_Stroke (NCT04576598)
- Testing
- Self-management program to increase physical activity levels, Education information
- Where
- 2 sites in Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Valencia
PreDiabetes
Efficacy of Physical Exercise on Glucose Control in People With Prediabetes
To assess the efficacy of different modalities and frequencies of physical exercise on glycaemic control in adults with prediabetes.
- Trial name
- GLYCEX (NCT05612698)
- Testing
- Aerobic training, Aerobic training plus resistance training, High intensive interval training
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
Metabolic Dysfunction-Associated Fatty Liver Disease
CPET-based HIIT for MAFLD
High-intensity interval training (HIIT), as an individualized exercise training mode based on cardiopulmonary exercise testing (CPET), is characterized by high-intensity training sessions interspersed with short rest periods.
- Trial name
- CEPHIT (NCT07177963)
- Testing
- HIIT, No specific exercise intervention.
- Where
- 5 sites in China
- Volunteers
- 54 people
- Sponsor
- Tang Yida
Distorted; Balance, Motor Deficit
Virtual Reality-Based Exercise in Cancer Patients
The aim of the present study is to evaluate an innovative virtual reality-based balance training intervention for improving clinically relevant motor performances (balance and gait) in cancer patients.
- Trial name
- NCT02165163
- Testing
- Balance Training
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Life Style, Healthy
Turkish Validation of the Core Life Activities Scale
This study aims to adapt the Core Life Activities Scale (CORE) into Turkish and evaluate its validity and reliability in Turkish-speaking adults.
- Trial name
- CORE-TR (NCT07762963)
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
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