Clinical trials: Physical Frailty
Frailty Syndrome
Validation of the Screening Instrument: PRISMA-7 for Frailty Among Elderly Hospitalized Danes
The questionnaire PRISMA-7 was originally developed to assess frailty in community dwelling adults. The questionnaire was translated into the Danish language.
- Trial name
- NCT03999047
- Testing
- PRISMA score
- Where
- Denmark
- Volunteers
- 1,050 people
- Sponsor
- Region Zealand
Physical Activity
Training Intervention in Heart Failure and Frail Elderly Population
There is enough scientific evidence of the benefits detection of frailty in patients with heart failure, which is an important prognostic factor.
- Trial name
- TIHFEP (NCT02365155)
- Testing
- Multicomponent training intervention., Nutrition intervention, Cognitive intervention
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Hospital de la Ribera
Frail Elderly Syndrome
HOPE (Healthy Older People Everyday) To Age in Place
Certain clinical syndromes eg frailty, sarcopenia, dementia, depression, cognitive impairment, vision impairment, falls in older adults carry an increased risk for poor health outcomes and if identified early, can be prevented…
- Trial name
- NCT03797352
- Testing
- Multicomponent exercise
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Chronic Lymphocytic Leukemia, Exercise
Effects of a Strength Physical Exercise Program in Chronic Lymphocytic Leukemia Patients
Chronic lymphocytic leukemia (CLL) is a hematological neoplasm that primarily affects older individuals and is the most common type of leukemia in adults in Western countries.
- Trial name
- NCT06654206
- Testing
- Exercise, Home exercise
- Volunteers
- 40 people
- Sponsor
- University of Salamanca
Breast Cancer, Frailty
Multicomponent Prehabilitation in Older Adults With Breast Cancer
Older adults with breast cancer frequently present with frailty, decreased functional reserve, and increased risk of postoperative complications.
- Conditions
- Breast Cancer, Frailty, Sarcopenia, Aging
- Trial name
- PREHAB-BC65 (NCT07531836)
- Testing
- Home-based Multicomponent Prehabilitation (Vivifrail), Supervised Multicomponent Prehabilitation, Comprehensive Geriatric Assessment and Optimization
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Fundacion Miguel Servet
Frail Elderly Syndrome, Frailty
Frailty Assessment by Edmonton Frail Scale to Predict Outcome in Patients Undergoing Cardiovascular Surgery
The aim of the study is to assess frailty of patients admited for cardio-vascular surgery in Cliniques Universitaires Saint Luc in Brussels.
- Conditions
- Frail Elderly Syndrome, Frailty, Surgery
- Trial name
- FRAIL-HEART (NCT03913299)
- Where
- 3 sites in Belgium
- Volunteers
- 2,080 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Heart Failure
Intervention by a Cardiologist and Geriatrician in Elderly Patients After Admission Due to Heart Failure.
Randomized clinical trial in which patients with a recent admission for heart failure in the cardiology department of the Hospital de Mar will be randomized to usual follow-up (cardiologist of the Heart Failure Unit) or follow-up…
- Trial name
- NCT03555318
- Testing
- Ambulatory visit, Combined ambulatory visit, Geriatric intervention
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Parc de Salut Mar
Cognitive Frailty
E-health Brisk Walking in Older People With Cognitive Frailty
Introduction Cognitive frailty is common in community-dwelling older people and is an at-risk state for adverse health outcomes such as dementia, dependency, and mortality.
- Trial name
- NCT05758740
- Testing
- E-health enhanced behavioural change intervention, Conventional behavioural change intervention
- Volunteers
- 184 people
- Sponsor
- Tung Wah College
Cirrhosis, Frailty
Prehab and Creatine/Whey Supplementation in Frailty Among Patients With Cirrhosis
Frailty and muscle health are important for patients with chronic liver disease. This study looks at the use of a digital prehabilitation app (HEAL-ME) plus creatine and whey protein combination supplementation on maintaining…
- Conditions
- Cirrhosis, Frailty, Sarcopenia
- Trial name
- NCT07029243
- Testing
- HEAL-ME digital app, Creatine supplementation, Whey protein supplementation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Cardiovascular Diseases+Liver Transplantation
Usefulness of Cardiopulmonary Exercise Testing for Cardiovascular Risk Estimation and Frailty Assessment in Liver Transplant Candidates
Patients undergoing liver transplantation (LT) have a high risk for cardiovascular disease (CVD). Frailty is a frequent condition among LT candidates.
- Trial name
- NCT04543825
- Testing
- Cardiopulmonary exercise testing
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- Andres Duarte-Rojo
Frailty, Mild Cognitive Impairment
E-health Enhanced Motor-cognitive Training for AED Discharged Older Adults With Cognitive Frailty
The goal of this pilot randomized controlled trial is to explore the feasibility of e-health enhanced motor-cognitive interventions for discharged community-dwelling older adults with cognitive frailty in the emergency department…
- Trial name
- NCT05750121
- Testing
- E-health enhanced motor-cognitive training
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University
Geriatric Assessment
Frailty Syndrome and Its Associated Factors Among Elderly Patients
This is a cross-sectional analytical study conducted among elderly patients attending Assiut university hospital. 2.4. 2- Study Setting:The study will be conducted in Assiut University hospital, including outpatients and…
- Trial name
- Frailty (NCT07727811)
- Volunteers
- 175 people
- Sponsor
- Assiut University
Inflammation, Frailty
Improving Physical Function in Older Adults Using an Anti-inflammation Drug: The RIGHT Study
The goal of this clinical trial is to learn about the effects of inflammation-lowering therapy on mobility and disability in older adults.
- Trial name
- RIGHT (NCT05727384)
- Testing
- Clazakizumab
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Anne B. Newman
Urinary Incontinence,Stress, Urinary Incontinence, Urge
Association of Urinary Incontinence With Depression, Insomnia, Frailty and Falls in Older Adults
The aim of our study is to provide a holistic analysis of the geriatric syndromes associated with urinary incontinence, which can result in significant adverse outcomes in the elderly, and to explore the gender-specific…
- Conditions
- Urinary Incontinence,Stress, Urinary Incontinence, Urge, Depressive Disorder, Insomnia
- Trial name
- NCT06627400
- Where
- Turkey (Türkiye)
- Volunteers
- 635 people
- Sponsor
- Kastamonu University
Frailty, Physical Inactivity
Effectiveness of Graded Training in the Vivifrail Exercise Program Among Long-Term Care Residents
This study evaluates the effectiveness of the Vivifrail multicomponent physical exercise program among elderly residents with different levels of frailty in long-term care centers.
- Conditions
- Frailty, Physical Inactivity, Aging
- Trial name
- NCT06975449
- Testing
- Multicomponent Physical Exercise Program (Vivifrail)
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Frailty at Older Adults
The engAGE Project: Immersive Intergenerational Intervention to Improve Movement in Older Adults
The engAGE project is an innovative, non-oriented research initiative that seeks to advance public health knowledge to promote quality of life and functional independence in older adults.
- Trial name
- engAGE (NCT07112638)
- Testing
- immersive technology-based intergenerational intervention to improve movement patterns in older adults
- Where
- 2 sites in Spain
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Ramon Llull
Elderly, Cancer
Suitability of an Organization With an Onco-geriatric Team to a Whole Region (Region Midt) of Denmark
A Feasibility study Geriatric assessment applied to patients with cancer of the head and neck, lung cancer, upper gastrointestinal cancer or colo-rectal cancer.
- Trial name
- NCT02072733
- Testing
- Comprehensive geriatric assessment
- Where
- Denmark
- Volunteers
- 320 people
- Sponsor
- University of Aarhus
Diabetes Type 2, Frail Elderly Syndrome
Involvement of Muscle Mitochondrial Dysfunction in Frailty in Older Adults. Role of Exercise
This study aims to investigate the role of skeletal muscle mitochondrial dysfunction in the development of frailty in older adults and to evaluate whether a short-term, supervised resistance training intervention can improve…
- Conditions
- Diabetes Type 2, Frail Elderly Syndrome, Mitochondrial Function, Bioenergetics, Functionality
- Trial name
- MITOSTRENGTH (NCT07828847)
- Testing
- Short-duration resistance training
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Fraility, Nutrition Assessment
Assessing the Relationship Between Frailty and Skeletal Muscle Thickness in Critically Ill Patients
Assessment of muscle mass in critically ill patients is critical for both improving clinical outcomes and monitoring the effectiveness of nutritional interventions.
- Conditions
- Fraility, Nutrition Assessment, Ultrasound Evaluation, Critical Illness
- Trial name
- NCT07310667
- Testing
- Muscle ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara Training and Research Hospital
Musculoskeletal Injury, Frailty
Exercise Engagement in People Over 60 at Risk of Falls
It is a qualitative study, using semi structured interviews to explore patient's experiences of falls and their perceptions on facilitators and barriers to exercise.
- Conditions
- Musculoskeletal Injury, Frailty, Physical Inactivity, Health Behavior
- Trial name
- NCT06100445
- Testing
- Semi structured interviews
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- East Lancashire Hospitals NHS Trust