Clinical trials: Physical Frailty
Rehabilitation, Training
The Effect of Modified Stepping Trainings in Frailty Elderly With Physical Performance- a Prospective Randomized Controlled Trial
This single-blind, randomized controlled trial compared the effects of modifiled stepping exercise training on flat step and unstable step on the functional outcomes in community-dwelling older adults.
- Conditions
- Rehabilitation, Training, Respiratory Muscle Strength
- Trial name
- NCT06505083
- Testing
- modified stepping trainings
- Where
- Thailand
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chonticha Kaewjoho
Urinary Incontinence (UI), Urinary Incontinence
URINARY INCONTINENCE AND GERIATRIC SYNDROMES
The aim of this cross-sectional observational study is to examine the independent associations of urinary incontinence severity and post-void residual urine volume with frailty and other geriatric outcomes in older adults…
- Conditions
- Urinary Incontinence (UI), Urinary Incontinence, Urinary Incontinence in Old Age, Urinary Incontinence in Geriatric Population
- Trial name
- NCT07813702
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- MERT UYSAL
Frailty, Older People
A Service-Learning Program for Comprehensive Geriatric Assessment and Health Promotion in Older Adults
The GEROS Project aims to develop and implement a Service-Learning (S-L) program that integrates Comprehensive Geriatric Assessment (CGA) and health promotion, for students at the Faculty of Health Sciences and Welfare at the…
- Conditions
- Frailty, Older People, Comprehensive Geriatric Assessment, Health Promotion
- Trial name
- GEROS (NCT06890325)
- Testing
- Comprehensive Geriatric Assessment (CGA), Health education
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Aging
Cycled Testosterone Therapy to Improve Physical Function in Frail Nursing Home Residents
Frailty is a recognized cause for disability, hospitalization, and mortality in nursing home residents. Testosterone treatment is among the potentially beneficial treatments in addition to resistance exercise for improving muscle…
- Trial name
- NCT02679274
- Testing
- Testosterone
- Where
- 2 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Frailty, Ventral Hernia
Targeted Prehabilitation With Physical Exercise and Inspiratory Muscle Training for Elderly Frail Patients Prior to Ventral Hernia Repair
The purpose of this study is to assess the physical fitness of patients undergoing hernia repair and correlate the postoperative outcomes and recovery as well as assess the impact of a targeted physical exercise program…
- Trial name
- NCT06874413
- Testing
- Prehabilitation, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Prisma Health-Upstate
Frailty, Sarcopenia
Frailty and Muscle Strength Tests in Older Adults Undergoing Major Surgery
The goal of this observational study is to learn if simple tests for frailty and muscle strength can help predict which older adults (age 65 and older) are at higher risk for problems after major abdominal surgery.
- Conditions
- Frailty, Sarcopenia, Sarcopenia in Elderly, Muscle Strength
- Trial name
- NCT06988176
- Testing
- Frailty assessment, nutrition assessment, cognition assessment, muscle strength testing
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
COPD (Chronic Obstructive Pulmonary Disease), Sarcopenia
Sarcopenia Predictors in Patients With COPD
Chronic obstructive pulmonary disease (COPD) is a significant, preventable, and treatable public health problem and a growing cause of chronic morbidity and mortality worldwide.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Sarcopenia, Frailty
- Trial name
- NCT07509528
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Hacettepe University
Patients Over 75 Years Old With a Cancer Discovery
Assessment of Positron Emission Tomography to Early Detect Frailty in Onco-geriatry
Oncogeriatric frailty assessment is a multifactorial approach to determine the most appropriate treatment for the health status of elderly cancer patients and this assessment is recommended for patients over 75 years of age.
- Trial name
- FOGTEP (NCT03370809)
- Testing
- Brain PET/CT step
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Central Hospital, Nancy, France
Cirrhosis, Frailty
Prehab and Creatine/Whey Supplementation in Frailty Among Patients With Cirrhosis
Frailty and muscle health are important for patients with chronic liver disease. This study looks at the use of a digital prehabilitation app (HEAL-ME) plus creatine and whey protein combination supplementation on maintaining…
- Conditions
- Cirrhosis, Frailty, Sarcopenia
- Trial name
- NCT07029243
- Testing
- HEAL-ME digital app, Creatine supplementation, Whey protein supplementation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Frailty at Older Adults
Enhancing Physical Reserve to Promote Resilience in Physically Frail Older Adults
The goal of this clinical trial is to assess the efficacy of combined aerobic and resistance training in enhancing physical reserve in older adults with physical frailty.
- Trial name
- MRI exercise (NCT07513701)
- Testing
- Aerobic and resistance training, Usual Care
- Where
- Hong Kong
- Volunteers
- 224 people
- Sponsor
- The Hong Kong Polytechnic University
Alzheimer Disease, Frail Elderly Syndrome
Comparison of Kinesiophobia, Balance, Falling and Walking Speeds of Elderly's With Physical Frailty With Alzheimer's
In this study, Kinesiophobia, Balance, Falling, Walking Speeds of Elderly People with Cognitive Frailty with Alzheimer's Dementia, Elderly with Physical Frailty and Healthy Elderly Individuals will be compared.
- Trial name
- NCT05761665
- Testing
- Evaluation
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Recurrent Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer
Frailty Index and Geriatric Assessment in Predicting Toxicity to Front-Line Chemotherapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer
This phase II trial is studying how well a frailty index and geriatric assessment works in predicting toxicity to front-line chemotherapy in treating patients with stage IV non-small cell lung cancer.
- Trial name
- NCT01026467
- Testing
- cisplatin, carboplatin, questionnaire administration
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Wake Forest University Health Sciences
Chronic Kidney Diseases, End Stage Renal Disease on Dialysis
A Study of Wrist Worn Accelerometers in End-Stage Renal Disease
The kidneys are important at getting rid of toxins and excess water from the body. If they fail, then toxins and excess water builds up within the body.
- Conditions
- Chronic Kidney Diseases, End Stage Renal Disease on Dialysis, Frailty
- Trial name
- W-WARD (NCT04860440)
- Testing
- GeneActiv wrist worn accelerometer
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Frailty
Understanding Changes in Physical Function Using Principles of Precision Medicine
This is a pilot, feasibility study and the purpose of this study is exploratory. The goal is to provide the PI and study team with data using metabolomics that can be used to: a) demonstrate an ability to use such data in a…
- Trial name
- NCT05581082
- Testing
- Pragmatic, exploratory study of Precision Medicine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Quality of Life, Aortic Valve Stenosis
Frailty and Cognitive Function Assessment of TAVI Patients
Aortic stenosis (AS) is the most common valve disease among the adult population, in the majority of the cases it only requires treatment in advanced age.
- Conditions
- Quality of Life, Aortic Valve Stenosis, Heart Valve Disease
- Trial name
- NCT02650388
- Testing
- Cognitive fuction, quality of life
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Hungarian Institute of Cardiology
Physical Activity
Training Intervention in a Controlled Population of Frail Elderly
Exercise has a beneficial role in geriatric patients categorized as frail. Nevertheless, it is not known physical training pattern more beneficial for these patients.
- Trial name
- EMTIFE (NCT02331459)
- Testing
- Multicomponent training intervention, Nutritional intervention
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital de la Ribera
Frailty, Pre-Frailty
In-Person, Online, and Hybrid Healthy-Aging Education for Pre-Frailty and Frailty in Older Adults
The goal of this clinical trial is to determine whether a 6-month healthy-aging education program delivered in person, online, or in a hybrid format reduces frailty and is cost-effective compared with usual care in…
- Trial name
- FRAGSALUD-ON (NCT07738393)
- Testing
- In-person healthy aging education program, Hybrid healthy aging education program, Online healthy aging education program
- Where
- Spain
- Volunteers
- 276 people
- Sponsor
- University of Cadiz
Frailty, Quality of Life
Impact of a Personalized Multicomponent Exercise Program in Real Conditions Among Older Adults With HIV
Longitudinal prospective multicenter study with intervention and control groups and a two-year follow up. Participants will include 40 sedentary adults 50 years old or older with HIV infection and 20 sedentary adults 50 years old…
- Conditions
- Frailty, Quality of Life, Physical Inactivity, Body Composition
- Trial name
- MOVIhNG (NCT05435521)
- Testing
- Personalized multicomponent exercise program (strength, resistance, balance, and flexibility) (PMEP), Body composition, Musculoskeletal and visceral Ultrasound
- Where
- 2 sites in Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Ramon y Cajal
Critical Care
Prediction of the Post-intensive Care Syndrome
The goal of this observational study is to assess whether a screening of patients at discharge from the intensive care unit (ICU) can predict psychological and physical problems three months later.
- Trial name
- PREPICS (NCT05690438)
- Where
- 4 sites in Sweden
- Volunteers
- 773 people
- Sponsor
- Region Stockholm
Old Age, Frailty
Activity and Health in Nursing Homes
There is expected to be an increased need for full time nursing homes as the increase in number of older adults increases and the rate of dementia diagnosis happens simultaneous with the decrees of healthcare personnel the years…
- Trial name
- NCT05037084
- Testing
- no intervention
- Where
- Norway
- Volunteers
- 1,123 people
- Sponsor
- Norwegian University of Science and Technology