Clinical trials: Physical Frailty
Cognitive Changes Due to Organic Disorder (Finding), Dementia
Gerontology Research Programme: The Singapore Longitudinal Ageing Studies (SLAS I & II)
The Gerontology Research Programme (GRP) in the National University Singapore's Department of Psychological Medicine, was formed to coordinate and facilitate the conduct of multi-disciplinary research on in a wide range of…
- Conditions
- Cognitive Changes Due to Organic Disorder (Finding), Dementia, Mild Cognitive Impairment, Frailty
- Trial name
- SLAS (NCT03405675)
- Testing
- SLAS 1, SLAS 2
- Where
- Singapore
- Volunteers
- 6,183 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Frailty, Older Adults
+AGIL Barcelona: Integrated Care for Community-Dwelling Frail Older Adults
The goal of this clinical trial is to evaluate the effectiveness of the +AGIL Barcelona program in helping older adults improve their physical abilities and delay disability.
- Conditions
- Frailty, Older Adults, Healthy Aging
- Trial name
- +AGIL (NCT06836167)
- Testing
- exercise promotion, review medication, promoting healthy aging
- Where
- 3 sites in Spain
- Volunteers
- 396 people
- Sponsor
- Parc Sanitari Pere Virgili
Aging
Physical Activity for Improving Quality of Life and Reducing Frailty in Advanced Age
Individuals of advanced age undergo both physical and cognitive deterioration. The aim of this study is to explore the connection between level of physical activity and health parameters, quality of life, and frailty.
- Trial name
- NCT01867112
- Testing
- Physical Activity
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
PROM, Satisfaction, Patient
Assessment of the Humanisation of Care in Hospitals in Andalusia-Spain
Observational assessment through patient interviews of relational, structural and organisational aspects related to the humanisation of health care.
- Conditions
- PROM, Satisfaction, Patient, Satisfaction, Personal, Stress
- Trial name
- HUMANCUIDA (NCT06174844)
- Testing
- No intervention applied
- Where
- Spain
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Seville
Mild Cognitive Impairment (MCI)
Optimising Exercise to Improve Physical and Cognitive Frailty in Mild Cognitive Impairment
This investigational research aims to understand the mechanism of delaying the progression of dementia through different types of exercise.
- Trial name
- NCT07600034
- Testing
- Exercise training
- Where
- Singapore
- Volunteers
- 36 people
- Sponsor
- Universiti Sains Malaysia
End Stage Renal Disease
CoQ10 and Exercise for Mitochondrial Dysfunction in Advance Kidney Disease
Frailty and sarcopenia are modifiable risk factors for morbidity and mortality in patients with ESRD. Exercise is the recommended intervention to prevent frailty and sarcopenia, however, many clinical trials have shown limited…
- Trial name
- NCT05422534
- Testing
- CoQ10, HB-HIIT, Observational
- Where
- 2 sites in United States
- Volunteers
- 156 people
- Sponsor
- Vanderbilt University Medical Center
Aging
Cycled Testosterone Therapy to Improve Physical Function in Frail Nursing Home Residents
Frailty is a recognized cause for disability, hospitalization, and mortality in nursing home residents. Testosterone treatment is among the potentially beneficial treatments in addition to resistance exercise for improving muscle…
- Trial name
- NCT02679274
- Testing
- Testosterone
- Where
- 2 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Neuropathic Pain, Old Age; Debility
Relationship Between Neuropathic Pain and Geriatric Assessment Parameters in Patients Aged 80 Years and Older
This study aimed to determine the frequency of neuropathic pain in individuals aged 80 years and older and to evaluate the relationship between neuropathic pain and comprehensive geriatric assessment parameters.
- Conditions
- Neuropathic Pain, Old Age; Debility, Pain
- Trial name
- NCT07487610
- Testing
- Detailed geriatric assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people
- Sponsor
- Sultan 1. Murat State Hospital
Frailty, Muscle Loss
A Randomized-Control Study of Gym Tonic's Community Based Strength Training Intervention.
Launched in April 2015 , Gym Tonic is the first of its kind cross-border exercise-as-medicine partnership between research institutions, business enterprises and service providers from Singapore and Finland.
- Conditions
- Frailty, Muscle Loss, Sarcopenia
- Trial name
- NCT04661618
- Testing
- Gym Tonic programme and Gym equipment
- Where
- Singapore
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- PulseSync Pte Ltd
Frailty Syndrome, Intelligent POWER Rehabilitation Cluster Machine
Development of an Intelligent POWER Rehabilitation Cluster Machine and Its Clinical Testing and Assessment
Elderly care has become one of the most important subjects in Taiwan and "frailty syndrome" are the most common problems among the elderly.
- Trial name
- NCT02685839
- Testing
- Intelligent POWER Rehabilitation Cluster Machine, general physical therapy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Frail Elderly Syndrome
Home-based Prehabilitation for Elderly Patients
As a consequence of the increasing life expectancy hospitals are seeing a growing number of elderly patients undergoing elective surgery.
- Trial name
- TRAilty (NCT03964363)
- Testing
- Unsupervised home-based physical prehabilitation
- Where
- 3 sites in Germany
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Frailty
Preoperative Frailty Assessment With Ultrasound in Elderly Patients
In this study, the investigators aim to evaluate the prediction accuracy of the thickness measured with point-of-care ultrasound of the rectus abdominis, biceps brachii muscles of frailty.
- Trial name
- NCT05438628
- Testing
- Point of care ultrasound
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Geriatric Assessment, Hip Fractures
Home-visits From geRiatric tEam aFter hIp fracTure
The primary objective is to examine the effect of multidisciplinary geriatric team home-visits as follow-up after a hip fracture in old patients.
- Conditions
- Geriatric Assessment, Hip Fractures, Frailty, Old Age; Atrophy
- Trial name
- REFIT (NCT04777136)
- Testing
- Home visit and comprehensive geriatric assessment, Control group, no designated follow up
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Herlev Hospital
Pre-frail, Pre-Frail Older Adults
The Impact of Whey Protein on Frailty in Older Adults Classified as Pre-frail
This pilot study aims to determine the impact of whey protein supplementation on brain antioxidant levels and to assess the effects of whey protein supplementation on physical function, body composition, and cognition in…
- Conditions
- Pre-frail, Pre-Frail Older Adults, Cognition, Physical Function
- Trial name
- NCT07167277
- Testing
- Whey Protein
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Kansas Medical Center
Frailty/Sarcopenia, Frailty in Older Adults
Effects of a Community-based Multicomponent Physical Exercise Program on Physical Function, Frailty, and Sarcopenia in Older Adults From the Municipality of Santoña: a Quasi-experimental Study.
This study evaluates the effects of a community-based multicomponent exercise program on physical function, frailty, and sarcopenia in older adults living in the municipality of Santoña (Cantabria, Spain).
- Conditions
- Frailty/Sarcopenia, Frailty in Older Adults, Sarcopenia
- Trial name
- NCT07732478
- Testing
- Multicomponent Exercise Program (Vivifrail-based)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Universidad de Granada
Frailty, Geriatric Syndromes
Beneficial Effects of an Integrated Program of Multicomponent Physical Exercise. Cohort Study
The study has been designed to analyze the possible positive effects of a multicomponent physical exercise program monitored with an integrated electronic device system in dwelling-community frailty older adults.
- Conditions
- Frailty, Geriatric Syndromes, Functional Recovery
- Trial name
- Ros-Ita (NCT04711785)
- Testing
- Multicomponent exercise program
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital de la Ribera
Elderly, Frail
Are Geriatric Out-patient Care Better Than Usual Care?
Frailty and multimorbidity is one of the biggest challenges of todays health care due to the demographic development with more and more elderly surviving many diseases that was mortal just a few decades ago.
- Trial name
- NCT02923843
- Testing
- Comprehensive Geriatric Assessment
- Where
- Sweden
- Volunteers
- 450 people
- Sponsor
- Region Skane
Frailty
Comprehensive Geriatric Assessment in the Emergency Department
Comprehensive geriatric assessment (CGA) has been shown to improve outcomes in an inpatient setting; however, there is currently no compelling evidence of benefit for CGA interventions within the Emergency Department (ED).
- Trial name
- NCT05252182
- Where
- Ireland
- Volunteers
- 133 people
- Sponsor
- University of Limerick
Frailty, Cancer
Predictive Value of Geriatric Oncology Screening and Geriatric Assessment in Older Patients With Solid Cancers
A Randomized Clinical Trial examining the effects of Comprehensive Geriatric Assessment as an add on to oncologic treatment. Participants included are cancer patients found eligible for oncologic treatment, age 70 or more, and…
- Conditions
- Frailty, Cancer, Age
- Trial name
- PROGNOSIS-RCT (NCT04686851)
- Testing
- Comprehensive Geriatric Assessment and follow-up
- Where
- Denmark
- Volunteers
- 322 people
- Sponsor
- Odense University Hospital
Cognitive Frailty, Physical Function
VR Motor-cognitive Training for Older People With Cognitive Frailty
Cognitive frailty is a clinical syndrome in which cognitive impairment (e.g., poor memory, visuospatial function) and physical frailty (e.g., slowness, poor muscle strength, physical inactivity) co-exist.
- Trial name
- NCT04730817
- Testing
- Virtual Reality Motor-Cognitive Training System
- Where
- 6 sites in Hong Kong
- Volunteers
- 400 people
- Sponsor
- The Hong Kong Polytechnic University