Clinical trials: Physical Frailty
Frailty Syndrome, Ischaemic Heart Disease
Cardiac Rehabilitation and Additional Physical Training in Elderly Patients After Acute Coronary Syndrome
The aim of this study is to evaluate functional and physical capacity, health-related quality of life and associations with frailty in older patients after ischemic heart disease and interventional treatment with an…
- Trial name
- NCT04768283
- Testing
- Additional balance and resistance training - 1, Additional balance and resistance training - 2
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lithuanian University of Health Sciences
Mild Cognitive Impairment
Effects of a Nutraceutic Compound on Cognitive Impairment
The study is designed to evaluate the effects of choline bitartrate on cognitive impairment in frailty patients. The study will analyze the impact of 4 weeks treatment randomized with a nutraceutical compound in a double-blind…
- Trial name
- ENUCCI (NCT06200883)
- Testing
- Choline Bitartrate
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- Federico II University
Recurrent Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer
Frailty Index and Geriatric Assessment in Predicting Toxicity to Front-Line Chemotherapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer
This phase II trial is studying how well a frailty index and geriatric assessment works in predicting toxicity to front-line chemotherapy in treating patients with stage IV non-small cell lung cancer.
- Trial name
- NCT01026467
- Testing
- cisplatin, carboplatin, questionnaire administration
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Wake Forest University Health Sciences
Fragility
Mobility Assessment & Follow-up in Frail Elderly: Clinic-technical Validation of a Smart Insole in Real Life
The investigators aim is to evaluate an instrument for supporting physical activity and monitors multiple parameters of frailty (a pre-disability condition) in frail elderly persons.
- Trial name
- RESPECT (NCT02316600)
- Testing
- smart insole
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Aging, Frailty
Intervention Study of Mind-Body Physical Activity in Frail Institutionalized Elderly
Few previous studies have explored the effects of mind body approaches on health-related quality of life (HRQoL) in frail elderly. Cognition and action are an inseparable whole while functioning.
- Trial name
- NCT00623532
- Testing
- Mind-body exercises, Adapted Tai-chi
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Association de Recherche Gerontologique
Frailty, Cognitive Decline
The Effectiveness of a Dual-task Training Program
The purpose of this study is to explore the effect of a dual-task training intervention on cognitive function,physical function, depression symptoms and quality of life in middle-aged and elderly people with cognitive impairment.
- Trial name
- NCT06450119
- Testing
- walking training, cognition training
- Volunteers
- 196 people
- Sponsor
- Taipei Medical University
Frailty
Secure and Focused Primary Care for Older pEople
The population worldwide is aging. The demographic change is challenging to health care organizations and highlights the need for effective preventive and proactive care models in primary care, especially for older people.
- Trial name
- SAFE (NCT05706272)
- Testing
- Comprehensive geriatric assessment (CGA), Care as usual
- Where
- 2 sites in Sweden
- Volunteers
- 4,000 people
- Sponsor
- Linkoeping University
Hip Fracture Surgeries, Geriatric Assessment
ASA or CFS for ICU Prediction in Geriatric Hip Fracture
The aim of this retrospective study is to compare the efficacy of the American Society of Anesthesiologists (ASA) physical status classification and the Clinical Frailty Scale (CFS) in predicting postoperative intensive care unit…
- Conditions
- Hip Fracture Surgeries, Geriatric Assessment, Frailty at Older Adults, Intensive Care
- Trial name
- NCT07522541
- Testing
- Routine Surgical and Anesthetic Mnagement.
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Frailty, Frailty Syndrome
Frailty Screening in the Swedish Emergency Department Setting
This prospective observational study will investigate the correlation of frailty in relation to serious outcomes. Serious outcomes are defined as: mortality within 30 days, admission to hospital, length of stay in the Emergency…
- Conditions
- Frailty, Frailty Syndrome, Emergency Department, Geriatric Assessment
- Trial name
- NCT04877028
- Where
- Sweden
- Volunteers
- 1,800 people
- Sponsor
- University Hospital, Linkoeping
Frailty
I4F: Isla for Frailty Feasibility Study
BACKGROUND: Older patients with frailty have complex support needs. How they manage with daily tasks such as eating and drinking, mobilising, communicating their preferences, and the level of support they need, can vary on a…
- Trial name
- I4F (NCT06504641)
- Testing
- Isla for Frailty
- Where
- United Kingdom
- Volunteers
- 95 people
- Sponsor
- Imperial College London
Kidney Transplant; Complications, Dialysis; Complications
Structured Program of Exercise for Recipients of Kidney Transplantation
Older patients with end- stage kidney disease (ESKD) are at very high risk for functional impairment. Kidney transplantation (KT) has the potential to ameliorate the detrimental effects of ESKD on physical activity and functional…
- Conditions
- Kidney Transplant; Complications, Dialysis; Complications, Physical Disability, Frailty Syndrome
- Trial name
- SPaRKT (NCT04954690)
- Testing
- Structured Program of exercise for Recipients of Kidney Transplantation (WC), Structured Program of exercise for Recipients of Kidney Transplantation (WC + CG), Usual Care
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University of California, San Francisco
Heart Disease, Physical Frailty
Genetics and Epidemiology of Aging Associated Conditions in the Sardinian Population
Background: The island of Sardinia, an Italian region, has a population that is highly interrelated. Researchers have developed the SardiNIA longitudinal study to examine the possible genetic factors that predispose individuals…
- Conditions
- Heart Disease, Physical Frailty, Exaggerated Personality Traits
- Trial name
- NCT00182949
- Where
- Italy
- Volunteers
- 6,926 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Aging, Physical Function
Movement and Behaviours Measurement Study
There are few studies that already have validated specific raw accelerometer cut-points for people over 65 years old. The purpose of the present study is to validate raw accelerometer cut points for general people over 65 years…
- Conditions
- Aging, Physical Function, Frailty Syndrome, Physical Disability
- Trial name
- MOBEMENTS (NCT04173715)
- Testing
- Older Adults Group., Low Physical Function Status Group, Medium Physical Function Status Group
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Caregivers
CAREGIVER2, Caregiver's Health Assessment : Clinical and Biological Markers
Providing care for a disabled elderly may represent a risk for the health of the caregiver. The objective of the study is to assess the impact of caregiving in terms of clinical and biological markers in relation to disability…
- Trial name
- NCT02521740
- Testing
- Research questionnaires, blood sample
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire UCLouvain Namur
Elderly Inpatients, Frail
Prevalence and Influencing Factors of Frailty in Elderly Patients With Heart Failure
The goal of this observational study is to investigate the prevalence and associated factors of frailty in hospitalized elderly patients with heart failure.
- Conditions
- Elderly Inpatients, Frail, Heart Failure Hospitalization, CGA
- Trial name
- NCT07510035
- Where
- China
- Volunteers
- 298 people
- Sponsor
- Zhejiang Hospital
Parkinson Disease
Determinants of Physical Frailty in Parkinson's Disease: A Multi-Factorial Analysis
The aim of this study is to examine the associations between motor imagery capacity, body awareness (interoceptive awareness), kinesiophobia, physical activity level, and symptom severity in individuals with Parkinson's disease.
- Trial name
- NCT07488364
- Testing
- Observational Questionnaire and Functional Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Acibadem University
Obesity, Frailty
Weight Loss and Exercise in Physically Limited Obese Elderly Subjects
The overall purpose of this research is to determine the effect of weight loss and physical training on quality of life, physical function, metabolism, bone strength, body fat and muscle mass.
- Conditions
- Obesity, Frailty, Elderly
- Trial name
- NCT00146133
- Testing
- diet, exercise
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Washington University School of Medicine
Chronic Kidney Disease, Cardiovascular Diseases
SEDentary Lifestyle, Mortality and Major Adverse Clinical Outcomes in Chronic KIDney Disease
The goal of this study is to learn if a simple home exercise program can benefit patients with advanced chronic kidney disease. There is also an observational part of the study without an exercise program.
- Conditions
- Chronic Kidney Disease, Cardiovascular Diseases, Frailty
- Trial name
- SEDKID (NCT06935786)
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION
- Where
- 3 sites in Finland
- Volunteers
- 400 people
- Sponsor
- Turku University Hospital
Heart Failure, Sarcopenia
The Sarcopenia Study
The goal of this cross-sectional study is to investigate the prevalence of sarcopenia in patients with Heart Failure. The main question it aims to answer is: Whether there is a difference in the prevalence of sarcopenia across…
- Conditions
- Heart Failure, Sarcopenia, Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction
- Trial name
- NCT05888688
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Weight Loss, Fatigue
Swiss Frailty Network and Repository
Physical frailty is an age-related medical syndrome defined by a decline in multiple body systems, thus causing increased vulnerability, even in the face of minor stressors (1) It has been linked to multiple negative health…
- Conditions
- Weight Loss, Fatigue, Physical Frailty, Weakness, Muscle
- Trial name
- SFNR (NCT04516642)
- Where
- Switzerland
- Volunteers
- 1,500 people
- Sponsor
- University of Zurich