Clinical trials: Physical Frailty
Bladder Cancer, Bladder Neoplasm
Preoperative Physical Activity Improvement With the Use of Activity Trackers Before Radical Cystectomy (PreAct)
A bicentric, open-label randomised controlled trial (RCT) is planned to investigate whether the use of fitness wristbands in a defined preoperative period prior to radical cystectomy leads to a preoperative increase in…
- Conditions
- Bladder Cancer, Bladder Neoplasm, Bladder Urothelial Carcinoma
- Trial name
- PreAct (NCT06416319)
- Testing
- Daily Activity Goal and Feedback
- Where
- 2 sites in Germany
- Volunteers
- 164 people
- Sponsor
- Universitätsmedizin Mannheim
Functional Disability, Dynapenia
Exercise Based on Proprioceptive Neuromuscular Facilitation in Older Individuals
The goal of this clinical trial was to determine whether an intervention using resisted sit-to-stand and walking exercises with Proprioceptive Neuromuscular Facilitation (PNF) techniques improved gait and sit-to-stand in older…
- Conditions
- Functional Disability, Dynapenia, Sarcopenia in Elderly
- Trial name
- NCT06690944
- Testing
- Proprioceptive Neuromuscular Facilitation, Physical exercise without proprioceptive neuromuscular facilitation control group
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Intrinsic Capacity, Frailty
Project ICOPE Brazil: Assessment of Intrinsic Capacity in Brazilian Older Adults
The ICOPE Brazil study aims to understand aging trajectories in Brazil, especially healthy aging trends based on intrinsic capacity, a collective of mental and physical capacities one may have to maintain their functional ability…
- Conditions
- Intrinsic Capacity, Frailty, Aging, Healthy Aging
- Trial name
- ICOPE-BR (NCT06968702)
- Volunteers
- 3,838 people
- Sponsor
- University of Sao Paulo
HIV Infections, Frailty
Sleep Quality and Frailty Among People Living With HIV
With effective antiretroviral therapy (ART), people living with HIV (PLWH) are living longer and are increasingly experiencing aging-related conditions such as frailty and sleep problems.
- Conditions
- HIV Infections, Frailty, Sleep Quality, Oral Frailty
- Trial name
- NCT07880054
- Testing
- No intervention (observational assessments)
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Sun Yat-sen University
Perioperative Complications
Clinical Frailty Assessment and Postoperative Adverse Outcomes and Quality of Life in Elderly Patients
The frailty index may represent a useful decision support tool to optimize modifiable drivers of the quality and cost of digestive surgery care.
- Trial name
- NCT05387850
- Testing
- no intervention
- Where
- China
- Volunteers
- 12,000 people
- Sponsor
- Chinese PLA General Hospital
Surgery-Complications, Cancer
The PREPARE for Cancer Surgery Study
Our team recently closed recruitment for the PREPARE Trial: PReoperative Exercise to decrease PostoperAtive complication Rates and disability scorEs.
- Conditions
- Surgery-Complications, Cancer, Frailty, Disability Physical
- Trial name
- NCT06503185
- Testing
- Prehabilitation
- Where
- Canada
- Volunteers
- 413 people
- Sponsor
- Ottawa Hospital Research Institute
Perioperative Care
Improvement of Perioperative Care of Elderly Patients
The focus of this study is the development of a perioperative treatment concept for elderly patients, based on individual necessities and risk factors, aiming to improve patient outcome.
- Trial name
- PeriAge (NCT03325413)
- Testing
- Systematic inclusion of family members, Preoperative information, Physical and breathing exercises
- Where
- Germany
- Volunteers
- 310 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Stability, Posturography
Acute Effects of Elastic Band Resistance on Postural Stability and Physical Function in Older Adults
Current balance and stability interventions have been shown to improve balance through targeting balance impairments and retraining effects.
- Conditions
- Stability, Posturography, Balance, Old Age; Debility
- Trial name
- NCT05224362
- Testing
- A repeated measures acute study using using elastic resistance bands in older adults to challenge stability.
- Where
- 2 sites in United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Derby
Frailty, Sarcopenia
FrAilty Care and wEll-funcTion in Community Dwelling Older Adults
This study is looking at whether older people could benefit from an online monitoring platform to support their individual ambitions to maintain or improve functional ability.
- Conditions
- Frailty, Sarcopenia, Aging
- Trial name
- FACET (NCT03707145)
- Testing
- Consultation, Online Support, Empowered
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Aberystwyth University
Frailty Syndrome, HIV Infections
Effectiveness of a Multifactorial Intervention in Frailty Individuals With HIV Infection: HIDRA360
The goal of this quasi-experimental before/after study without equivalent control group is to to describe the prevalence of frail, pre-fragile and robust individuals in the study group before and after a multifactorial…
- Trial name
- HIDRA360 (NCT05832164)
- Testing
- Multifactorial intervention
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Hospital Costa del Sol
Cancer, Frailty
Geriatric Oncology SuPportive Clinic for ELderly
This is a randomized controlled trial comparing the impact of Geriatric-Oncology-Supportive Clinic (GOSC) on quality of life in older adult with newly diagnosed cancer undergoing cancer related treatment.
- Trial name
- GOSPEL (NCT04513977)
- Testing
- Geriatric Oncology Supportive Clinic
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- Goh Wen Yang
Frailty
Multimodal, Task-Aware Movement Assessment and Control: Clinic to the Home
The investigators seek to construct a novel, multimodal, distributed system that facilitates a new paradigm of home-based medical surveillance and treatment for frail older adults centered on timely diagnosis of movement system…
- Trial name
- NCT04675307
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Frailty, Disability Physical
Functional Decline and QoL in People Aging with HIV in Asia
This is a multi-center prospective cross-sectional study to determine the burden of decline in intrinsic capacity and functional ability, and the prevalence of geriatric syndromes, such as frailty, and disability in adult people…
- Conditions
- Frailty, Disability Physical, HIV/AIDS
- Trial name
- NCT04212884
- Where
- 2 sites in Hong Kong
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Dementia, Dementia, Mild
Chocolate and Physical Exercise to Reduce Malnutrition in Pre-dementia Aged People
We hypothesize that the antioxidant and cytoprotective functions of vitamin E combined with the cortisol-lowering effect of chocolate polyphenols and physical activity may help prevent the age-dependent decline of mitochondrial…
- Conditions
- Dementia, Dementia, Mild, Dementia Moderate, Dementia Senile
- Trial name
- Choko-AGE (NCT05343611)
- Testing
- Combination of High Protein Diet and Physical Exercise protocol, HPP Choko, HPP/VE Choko
- Where
- 4 sites in Italy
- Volunteers
- 102 people
- Sponsor
- Massimo Venturelli, PhD
Mild Cognitive Impairment, Frailty
Cognitive Frailty in Older Adults: The Role of Technology in Physical Activity Enhancement
This study intends to determine if smart watches and mobile phone application prompts can complement physical activity as a preventive intervention by motivating participants to exercise, so as to improve their physical and…
- Trial name
- NCT04692974
- Testing
- Mobile phone application and smart watch
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Old Age, Frailty
Effects of Physical Exercise on Frailty, Mental and Physical Health of Older Adults in Rural Areas.
Global aging is a significant challenge, both economically and in terms of public health. One of the main challenges is to maintain the health and functionality of older adults.
- Trial name
- Rural-Frail (NCT06556537)
- Testing
- Face-to-face and video-assisted training
- Where
- Spain
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Frail Elderly Syndrome
Development of Clinical Indicators From the Swiss RAI-HC
The project aims at deriving frailty (FI) and complexity (CI) indices from data collected with the Resident Instrument Assessment - Home Care adapted for Switzerland (RAI-HC).
- Trial name
- IndiRAI (NCT03139162)
- Testing
- Swiss RAI-HC assessment
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- School of Health Sciences Geneva
Mild Cognitive Impairment (MCI)
Cognitive-Frailty Gait Biomechanics for Early Dementia Detection
The purpose of this study is to better understand how physical characteristics, walking patterns, and a blood-based brain health marker differ between older adults with dementia and healthy older adults.
- Trial name
- gait dementia (NCT07448909)
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Physical Disability, Cognitive Dysfunction
Study on Cardiovascular Health, Nutrition and Physical Functioning in Older Adults in Spain
Population aging makes it necessary to identify factors related to unhealthy aging. The purpose of this study is to examine the association between ideal cardiovascular health, diet and other lifestyles and biological risk…
- Trial name
- Sen-ENRICAII (NCT03541135)
- Where
- Spain
- Volunteers
- 4,000 people
- Sponsor
- Universidad Autonoma de Madrid
Myocardial Infarction, Frailty
Management and Outcomes of Patients Admitted to Coronary Care Units, Depending on Degree of Frailty and Comorbidities
Background Patients less than 80 years of age, who suffer a myocardial infarction (MI) are usually (>90%) offered an early invasive strategy including coronary angiography possibly followed by intervention, preferably…
- Trial name
- NCT04488536
- Testing
- Clinical Frailty Scale
- Where
- 2 sites in Sweden
- Volunteers
- 10,000 people
- Sponsor
- Linkoeping University