Clinical trials: Physical Function
Sarcopenia
A Comparison of the Effects of Krill Oil and Fish Oil Supplementation on Muscle Function in Older Adults
The aim of the study is to compare the effects of Krill Oil and Fish Oil supplementation on muscle function in older adults. The secondary aim is to investigate the mechanisms underlying the beneficial effects previously observed.
- Trial name
- NCT05869526
- Testing
- Fish oil, Kril oil, Vegetable oil
- Where
- United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Healthy Subjects, Dyslipidaemias
Study To Evaluate The Effects Of GW856553 On Endothelial Function/Vascular Compliance In Subjects With Dyslipidaemia.
The rationale for this study is to determine whether GW856553 (7.5mg BD for 28 days) has an effect on endothelial function in dyslipidaemic subjects as assessed by venous occlusion plethysmography using brachial artery…
- Conditions
- Healthy Subjects, Dyslipidaemias, Dyslipidaemia
- Trial name
- NCT00474864
- Testing
- GW856553
- Where
- 3 sites in United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cardiovascular Diseases
Effects of California Walnuts on Vascular Function in Postmenopausal Women
To determine the potential acute cardiovascular benefits of California Walnuts in postmenopausal women of ages 55-70. Primary outcome measures: Vascular function Platelet reactivity We hypothesize that the consumption of…
- Trial name
- NCT01072864
- Testing
- Walnuts
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Facial Paralysis, Bell Palsy
Function and Form Outcomes in Patients With Facial Paralysis
This study will be unique for the rehabilitation of patients with facial paralysis in that the focus is to generate novel 3D facial soft tissue measures to characterize the condition and temporal changes, and on the generation of…
- Trial name
- NCT03974763
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Tufts University
Traumatic Brain Injury, Major Depressive Disorder
Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations
In the current study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in improving executive function across neuropsychiatric populations known to have deficits in this cognitive…
- Conditions
- Traumatic Brain Injury, Major Depressive Disorder, Bipolar Disorder, Schizophrenia
- Trial name
- NCT04296604
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Aging
Everyday Memory Intervention
Evaluates an intervention designed to improve everyday memory function, contrasting people receiving the intervention with a group that receives traditional memory strategy training.
- Trial name
- EMMI (NCT04088136)
- Testing
- Everyday Metacognitive Memory Intervention, Memory Strategy Control Intervention
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Healthy
Natreon Healthy Skin Study - PrimaVie Supplement
This study will demonstrate the ability of the oral supplement, PrimaVie® to improve skin microperfusion, hydration, elasticity and barrier function.
- Trial name
- NCT02762032
- Testing
- PrimaVie Herbal Supplement 125, PrimaVie Herbal Supplement 250
- Where
- 3 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Type 2 Diabetes
Exercise Resistance in Type 2 Diabetes
The purpose of this study is to collect data to help researchers identify factors that prevent certain individuals from receiving the beneficial effects of exercise.
- Trial name
- RESIST (NCT01911104)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Diaphragm Pacing
Effects of Combined Thoracic and Diaphragmatic Breathing on Cognitive and Psycho-Physiological Functions
This study aims to investigate the effects of a combined thoracic expansion exercise (TEE) and slow diaphragmatic breathing (SDB) program on cognitive function, brain activation, psychological status, and head-shoulder posture in…
- Trial name
- NCT07620249
- Testing
- thoracic expansion exercises and slow diaphragmatic breathing
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Clinical Trial Center
Prostate Cancer, Hypothermia
MRI Temperature Mapping of the Prostate and Urogenital Pelvis Cooled by an Endorectal Balloon
Urinary incontinence and sexual dysfunction are potential side effects for men undergoing the successful removal of the cancerous prostate via surgery.
- Conditions
- Prostate Cancer, Hypothermia, Urinary Incontinence, Erectile Dysfunction
- Trial name
- NCT01979848
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Physical Activity, Sedentary Behavior
B4B Evolution Type II Hybrid Effectiveness-Implementation Trial
Break4Brain Evolution is a school-based programme designed to help teachers incorporate brief, safe and inclusive movement activities into normal classroom routines.
- Conditions
- Physical Activity, Sedentary Behavior, Cognition, Academic Acheivement
- Trial name
- B4B Evolution (NCT07726732)
- Testing
- Break4Brain Evolution
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
Alzheimer s Disease
TSPO Modulation in AD
The aim of this study is to determine whether pharmacological modulation of TSPO (with XBD173, 90mg twice daily, orally, for 28 days) improves neurovascular coupling (NVC) in AD relative to placebo.
- Trial name
- NCT07191821
- Testing
- XBD173
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Mild Cognitive Impairment
Using fMRI-guided TMS to Increase Central Executive Function in Older Adults (MCI_Sub)
This is an administrative supplement to an existing project "Using fMRI-guided TMS to increase central executive function in older adults: NCT02767323" This award allows extending our existing fMRI-TMS paradigm to patients with a…
- Trial name
- MCI_Sub (NCT04176406)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Duke University
Idiopathic Inflammatory Myopathy, Dermatomyositis
Muscle Function and Effects of Repetitive Task Training in Patients With Inflammatory Myopaties
Idiopathic inflammatory myopathies lead to important functional limitations resulting from the loss of muscle strength and endurance, especially in the hip and shoulder, which leads to a significant loss of quality of life for…
- Conditions
- Idiopathic Inflammatory Myopathy, Dermatomyositis, Polymyositis
- Trial name
- NCT05027152
- Testing
- Repetitive task training
- Where
- Brazil
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Federal University of Espirito Santo
Cardiac Autonomic Function, Hemodynamic Changes
Effects of Post-Match Foam Rolling, Static Stretching, and Passive Rest on Acute Cardiac-Autonomic, Hemodynamic, and Neuromuscular Recovery in National Wrestlers
This study looks at three common ways athletes recover after a wrestling match: foam rolling, static stretching, and resting. We want to learn which method helps the body recover better in the short time that athletes often have…
- Conditions
- Cardiac Autonomic Function, Hemodynamic Changes, Neuromuscular Adaptations, Exercise and Recovery
- Trial name
- NCT07305506
- Testing
- Foam Rolling, Static Stretching
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ali Kamil GÜNGÖR
Hepatic Impairment
A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Normal Hepatic Function and Participants With Hepatic Impairment
The primary purpose of the study is to determine the effect of mild, moderate, and severe hepatic impairment on the PK of total treprostinil palmitil (TP) and treprostinil (TRE) following a single dose of 80 micrograms (μg) TPIP…
- Trial name
- NCT07643155
- Testing
- Treprostinil Palmitil Inhalation Powder
- Where
- 4 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Insmed Incorporated
Obesity, Insulin Sensitivity, Type 2 Diabetes Mellitus
Dietary Polyphenols and Lipid Oxidation
There are strong indications that (combinations of) polyphenols may be attractive candidates in the prevention of the metabolic syndrome and diabetes through modulation of pathways of fatty acid metabolism and mitochondrial…
- Trial name
- NCT01302639
- Testing
- Comparison of different combinations of polyphenols with respect to effects on fat oxidation
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Dehydration
Measuring Pain and Hydration After Tonsillectomy
Pain after tonsillectomy remains a key barrier during the post operative period. The published return rate to the emergency department for hydration and pain control is approximately 4%.
- Trial name
- NCT02011230
- Testing
- Hoist Group
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Scoliosis Idiopathic, Scoliosis; Adolescence
Back Muscle Function in Adolescents With Idiopathic Scoliosis
The function and asymmetry of back muscles will be examined in different positions and with specific spinal corrections based on scoliosis pattern and according to the "Schroth method" in adolescents with idiopathic scoliosis.
- Trial name
- NCT05961228
- Testing
- exercise
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Emphysema
Smoking Cessation and Functional CT Assessment
The investigators will study the effect of pulmonary arterial vasodilation to see if it eliminates indices of persistent lung injury in smokers that are susceptible to emphysema.
- Trial name
- NCT03382106
- Testing
- Sildenafil 20 MG, Pulse wave velocity, Carotid artery compliance and stiffness
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Eric A. Hoffman