Clinical trials: Physical Mobility Impairment
Creatine, Exercise
Creatine and Resistance Training in Older Adults With Mild Cognitive Impairment
The goal of this 26-week trial is to learn if creatine supplementation and resistance training (i.e., weightlifting; exercise that increases muscle mass), alone and together, impact cognition, brain health, and physical function…
- Conditions
- Creatine, Exercise, Mild Cognitive Impairment (MCI)
- Trial name
- NCT06948149
- Testing
- Creatine monohydrate, Resistance training
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Western University, Canada
Mobility Limitation, Fall
Exercise for Adults With Limited Mobility
The purpose of this study is to evaluate the effectiveness of a structured and progressive task-oriented, community based exercise program for older adults who have limitations in mobility and examine whether improvements in…
- Trial name
- NCT05266573
- Testing
- Exercise Group
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Youngstown State University
Parkinson Disease
Pulmonary and Musculoskeletal Impairments in Parkinson's Patients
In this study, the relationships between pain severity, chest mobility, cough strength, muscle strength, physical activity levels, and quality of life in Parkinson's disease patients will be investigated.
- Trial name
- NCT07843667
- Testing
- Physical Evaluations of Individuals with Parkinson's Disease
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Izmir Democracy University
Amyotrophic Lateral Sclerosis, Motor Neurone Disease
Measurement and Impact of Physical Impairment in Amyotrophic Lateral Sclerosis: Use of Digital Technologies - A Precision ALS Project
Amyotrophic Lateral Sclerosis (ALS), the most common form of Motor Neuron Disease (MND), is a neurodegenerative disease. At present there are limited treatment options for this disease which progressively affects physical…
- Trial name
- TechnicALS (NCT06820008)
- Where
- Ireland
- Volunteers
- 60 people
- Sponsor
- University of Dublin, Trinity College
Bed-ridden Patient, Solid Organ Transplant
Use of an Off-the-Shelf Exergame as an In-Bed Gamified Rehabilitation Intervention for Severely Deconditioned Inpatients: A Feasibility Study
1. Study Title: Use of an Off-the-Shelf Exergame as an In-Bed Gamified Rehabilitation Intervention for Severely Deconditioned Inpatients: A Feasibility Study 2.
- Conditions
- Bed-ridden Patient, Solid Organ Transplant, Post Critical Care
- Trial name
- NCT06937463
- Testing
- Rehabilitation
- Where
- South Korea
- Volunteers
- 26 people
- Sponsor
- Asan Medical Center
Femoroacetabular Impingement Syndrome, Healthy Participants
Mobility, Strength, and Functional Outcomes Before Surgery, at 3 Months, and at 6 Months After Hip Arthroscopy for Femoroacetabular Impingement Syndrome
The aim of this study is to identify the factors associated with successful rehabilitation following hip arthroscopy for femoroacetabular impingement syndrome and to highlight any persistent functional deficits at different key…
- Trial name
- NCT07472400
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Liege
Peripheral Neuropathy With Type 2 Diabetes, Peripheral Neuropathy Grade 2 or Greater
Wearable Sensory Prosthesis to Improve Coordination, Walking, and Physical Activity
The goal of this clinical trial is to investigate whether sensory stimulations from a neuroprosthesis device (Walkasins®) can increase physical activity and improve gait quality in persons with peripheral neuropathy (PN).
- Conditions
- Peripheral Neuropathy With Type 2 Diabetes, Peripheral Neuropathy Grade 2 or Greater, Balance, Balance Impairment, Gait Disorders, Fatigue
- Trial name
- NCT07554443
- Testing
- External, lower limb sensory prosthesis
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- RxFunction Inc.
Fall
Effects of Balance Training on Fall Risk and Mobility in the Elderly
Pakistan is a country devoid of health-care facilities and training programs on fall prevention. There is lack of research, awareness and implication of geriatric rehabilitation on elderly population addressing balance and fall…
- Trial name
- NCT03656458
- Testing
- Warm Up, Conventional Balance Training, Biodex Balance Training
- Where
- Pakistan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Intrinsic Capacity, Frailty
Project ICOPE Brazil: Assessment of Intrinsic Capacity in Brazilian Older Adults
The ICOPE Brazil study aims to understand aging trajectories in Brazil, especially healthy aging trends based on intrinsic capacity, a collective of mental and physical capacities one may have to maintain their functional ability…
- Conditions
- Intrinsic Capacity, Frailty, Aging, Healthy Aging
- Trial name
- ICOPE-BR (NCT06968702)
- Volunteers
- 3,838 people
- Sponsor
- University of Sao Paulo
Burn Injury, Physical Injury
STAT: Standard Therapy Plus Active Therapy
The objective of the study is to assess the efficacy of STAT, an activity-based therapy protocol compared to standard therapy (ST) to improve functional outcome and reduce disability in patients recovering from burn injury.
- Conditions
- Burn Injury, Physical Injury, Thermal Burn
- Trial name
- STAT (NCT04368117)
- Testing
- Physical Therapy
- Where
- 7 sites in United States
- Volunteers
- 166 people
- Sponsor
- American Burn Association
Aging Disorder
Physical Impairments in Elderly Individuals
There are no studies in the literature reporting the dyspnea, posture, strength, physical activity, functional mobility and balance in elderly individuals.
- Trial name
- NCT06267625
- Testing
- Physical Evaluations of individuals
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
People With Trans-femoral Amputation
Effects of Microprocessor-controlled Knee Joints on Community Outcomes
About 21% to 35% of people with limb loss are those who lost their limb at trans-femoral level (i.e. above the knee). The increasing number of diabetes-related limb loss (amputation) and the rising proportion of older adult…
- Trial name
- NCT04112901
- Testing
- Microprocessor-controlled knee joints, Non-microprocessor-controlled knee joints
- Volunteers
- 330 people
- Sponsor
- University of Derby
Older Adults, Multiple Sclerosis
Exercise Training, Cognition, and Mobility in Older Adults With Multiple Sclerosis
The overall objective of the proposed randomized controlled (RCT) is to determine the feasibility and efficacy of a 16-week theory-based, remotely-delivered, combined exercise (aerobic and resistance) training intervention for…
- Conditions
- Older Adults, Multiple Sclerosis, Cognitive Impairment, Walking Impairment
- Trial name
- NCT05930821
- Testing
- Aerobic and Resistance Exercise Program (GEMS program), Flexibility and Stretching Program (FLEX-MS program)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Illinois at Chicago
Obesity, Breast Cancer
Simulated-altitude to Optimize Aerobic Exercise Among Breast Cancer Survivors With Limited Mobility
The study will evaluate the utility of hypoxic exercise training to improve cardiovascular and metabolic health among obese breast cancer survivors.
- Trial name
- NCT03029182
- Testing
- Walking+simulated-altitude, Walking (control)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Alabama at Birmingham
Old Adults, Sleep Quality
Kava Aging and Mobility Study
The goal of this clinical trial is to learn if AB-free kava works to improve mobility and physical function in older adults with sleep difficulties. It will also learn about the safety of AB-free kava.
- Conditions
- Old Adults, Sleep Quality, Kava, Mobility Impairment
- Trial name
- NCT07219186
- Testing
- AB-free kava
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Florida
Spinal Cord Injury (SCI), Gait
Closed-Loop Vagus Nerve Stimulation (CLV) for Recovery of Gait After Spinal Cord Injury (SCI)
The purpose of this study is to evaluate the safety, feasibility, and preliminary effectiveness of the ReWire system, which delivers vagus nerve stimulation (VNS) paired with lower limb rehabilitation to improve gait in…
- Conditions
- Spinal Cord Injury (SCI), Gait, Reduced Physical Activity, Lower Limb Functions
- Trial name
- NCT07689227
- Testing
- CLV
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas at Dallas
HIV/AIDS, Cognitive Impairment
A Randomized Pilot Trial Evaluating the Impact of a Yoga Intervention on Cognition in Older Adults Infected With HIV
Approximately 50% of people living with HIV (and as many as 80% over the age of 50) have difficulties with cognitive functions such as memory and thinking that can have a profound negative impact on activities of daily living and…
- Conditions
- HIV/AIDS, Cognitive Impairment, Aging, Mobility Limitation
- Trial name
- NCT03071562
- Testing
- Yoga-mindfulness
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Adria Quigley
Pressure Injury, Limitation, Mobility
Effect of Structured Pressure Injury Patient Education
This study was planned as a prospective quasi-experimental study with the control group to determine the effect of structured pressure injury patient education (program on the knowledge, participation, wound healing progress, and…
- Trial name
- SPIPE (NCT04944186)
- Testing
- Structured Pressure Injury Patient Education (mySPIPE), Standard Patient Education
- Where
- Malaysia
- Volunteers
- 116 people
- Sponsor
- University of Malaya
Physical Disability
Feasibility of An Active Video Gaming Intervention
Replacing sedentary behaviors during leisure time with active video gaming (AVG) has been shown to be an enjoyable option for increasing the amount of physical activity acquired each week.
- Trial name
- NCT05310279
- Testing
- GAIMplank
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pain, Disability Physical
Study of Manual Therapy Plus Therapeutic Exercise in Geriatrics
This research project is part of the process of generating scientific evidence, on whether the clinical results obtained, in the treatment of the consequences of aging on mobility, pain and disability, are better if therapeutic…
- Conditions
- Pain, Disability Physical, Aging Disorder
- Trial name
- NCT05085535
- Testing
- Manual Therapy, Exercise
- Volunteers
- healthy volunteers welcome
- Sponsor
- Juan Vicente, López Díaz