Clinical trials: Physiological Responses
Aging, Cognitive Decline
Augmented Reality Treadmill Walking for Cognitive and Physical Health in Older Adults
This study evaluated the feasibility and health effects of using augmented reality (AR) treadmill walking in older adults. Sixty community-dwelling adults aged 65 to 80 years were randomly assigned to either an AR treadmill group…
- Conditions
- Aging, Cognitive Decline, Sarcopenia, Mobility Limitation
- Trial name
- ART-Walk (NCT07074613)
- Testing
- Traditional Treadmill Walking, JOHNSON 8.1T treadmill with Passport AR system
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan College of Performing Arts
Resistance Training, Sports Nutrition
Effects of Three Carbohydrate Beverages on Resistance Training Performance
This randomized, triple-blinded, counterbalanced crossover trial compared three carbohydrate beverages that provided the same amount of carbohydrate (30 g) but differed in carbohydrate source: dextrose, maltodextrin, and highly…
- Conditions
- Resistance Training, Sports Nutrition, Dietary Carbohydrates
- Trial name
- NCT07874776
- Testing
- Dextrose, Maltodextrin, Highly Branched Cyclic Dextrin
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Erectile Dysfunction, Depression
Depression Related Improvement With Vardenafil for Erectile Response
The study will last three months. During the first month of treatment the subject will receive either 10 mg vardenafil or placebo.
- Trial name
- DRIVER (NCT00661219)
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 280 people
- Sponsor
- Bayer
Physiological Responses to Contact With Dogs, Psychological Responses to Contact With Dogs
Measuring Effects of Contact to Dogs
The study aims to identify and quantify objective non-invasive measures of the immediate effect of contact with dogs in a standardized experimental setup.
- Conditions
- Physiological Responses to Contact With Dogs, Psychological Responses to Contact With Dogs, Behavioural Responses to Contact With Dogs
- Trial name
- NCT04696419
- Testing
- Different intensities of contact to dogs
- Where
- Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Stress Response, Mental Stress
Cranberry Polyphenols and Stress Resilience During Multitasking in Healthy Adults
This randomized, double-blind, placebo-controlled clinical trial evaluates whether 70 days of daily cranberry juice consumption improves cognitive performance and motor accuracy and reduces psychological and physiological stress…
- Conditions
- Stress Response, Mental Stress, Multitasking Behavior and Multitasking Ability, Physiological Stress
- Trial name
- CRAN-MULTI (NCT07453537)
- Testing
- Cranberry juice
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Florida
Baro-reflex Sensitivity, Heart Rate Variability
Low Intensity Exercise in Different Normobaric/Hypobaric Normoxic/Hypoxic Conditions.
The main goal of this project is to investigate how low intensity cycling exercise (1.5W/kg, for 6 minutes) influences cerebral functions, such as: Cerebral blood flow, oxygenation, and other physiological variables in different…
- Conditions
- Baro-reflex Sensitivity, Heart Rate Variability, EEG, Microstates, Cerebral Blood Flow Regulation
- Trial name
- Hypoxia (NCT03439202)
- Testing
- Hypoxia
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fliegerärztliches Institut
Health Adult Subjects, Pressure Injury Prevention
A Trial to Investigate the New Caulis Pro® Low Air Loss (LAL) System
Investigation of biomechanical and physiological functions of laying on a new mattress in healthy volunteers.
- Trial name
- NCT07213739
- Testing
- CLP and pulsation
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Arjo AB
Sports Nutritional Physiological Phenomena
Consistencies in Responses to Sodium Bicarbonate?
Intervention studies do not account for high within-individual variation potentially compromising the magnitude of an effect. Repeat administration of a treatment allows quantification of individual responses and determination of…
- Trial name
- NCT02474628
- Testing
- sodium bicarbonate, calcium carbonate
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Pain
Safety and Effects on Responses to Stress and Pain of Natural Medical Marijuana Products
This proposal aims to systematically examine the safety and pharmacokinetic/pharmacodynamic profile and the physiologic, neuroendocrine and behavioral stress and pain responses to acute single doses and repeated dosing of oral…
- Trial name
- NCT04226690
- Testing
- Active CBD/THC Dose 1, Active CBD/THC Dose 2
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Yale University
Breast Cancer Survivors
Effects o Laughing Qigong Program on Psychological Outcomes and the Physiological Immunological Responses
Laughter programs are safe, affordable, and age-appropriate activities. Few studies have utilized mixed study designs to look at the impact on resilience in and experiences of participants in such activities.
- Trial name
- NCT05793710
- Testing
- The principle of laughter plus Qigong
- Where
- Taiwan
- Volunteers
- 71 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Exercise Physiology
Comparing Acute Aerobic and Resistance Exercise
The purpose of this study is to determine the effect of age and fitness level on the physiological response to an acute bout of resistance or aerobic exercise.
- Trial name
- CAARE (NCT03794050)
- Testing
- Resistance training exercise, Aerobic training exercise
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Houston
Dental Anxiety, Musical Therapy
Effects of Different 432 Hz Auditory Stimuli on Physiological Stress Responses and Patient Satisfaction in Adults With Dental Anxiety During Restorative Treatment
In this four-arm randomized controlled clinical trial, 120 adults aged 18-50 years with baseline Modified Dental Anxiety Scale scores ≥13 were allocated equally to 432 Hz-based instrumental music, water sounds, human-vocal music…
- Conditions
- Dental Anxiety, Musical Therapy, Physiological Stress
- Trial name
- RCT (NCT07903844)
- Testing
- Music Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Athletic Performance, Dietary Supplement
The Effects of Acute Nitrate and Caffeine Co-ingestion on Discipline-Specific Exercise Performance.
The purpose of this study is to investigate the acute, separate, and combined ergogenic effects of dietary nitrate (beetroot juice, BJ) and caffeine (CAF) supplementation on discipline-specific athletic performance.
- Conditions
- Athletic Performance, Dietary Supplement, Iron Status
- Trial name
- NCT07748416
- Testing
- Caffeine, Dietary Nitrate (Beetroot Juice)
- Where
- Poland
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Allergy Testing, Pain, Emotional Symptoms and Physiological Parameters
Pet Therapy Effects on Pain, Emotional and Physiological Responses in Children Undergoing Allergy Testing
In recent decades, the prevalence of allergic diseases, particularly respiratory allergies, has risen significantly. In childhood, house dust mites are the primary indoor allergen in infancy, while the prevalence of pollen…
- Trial name
- NCT06875999
- Testing
- animal assisted therapy
- Volunteers
- 80 people
- Sponsor
- Mehtap METİN KARAASLAN
Diabetic Ketoacidosis, Heart Disease, Ischemic
Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient
Music intervention is a non-pharmacological and effective intervention that can alleviate anxiety and agitation in patients undergoing weaning.
- Conditions
- Diabetic Ketoacidosis, Heart Disease, Ischemic, Stroke, GastroIntestinal Bleeding
- Trial name
- NCT04977011
- Testing
- relaxing music
- Where
- Taiwan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
Osteoarthritis, Chronic Pain
Physiological Impact of Different Types of Osteoarthritis Education.
In this study, the investigators are comparing two types of education for older adults with knee osteoarthritis: standard biomedical education focusing on the disease process, and a newer approach called pain neuroscience…
- Trial name
- PNE (NCT06400329)
- Testing
- Pain Neuroscience Education, Standard Pain Education
- Where
- Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Lisa Carlesso
Obesity
Effects of Sweetness on Neurocognitive Responses, Glycemia and Food Intake
This study aims to examine potential differences in neurocognitive responses to food-related cues, physiological and appetite responses as well as subsequent energy intake following the consumption of preloads differing in…
- Trial name
- NCT03711084
- Testing
- Natural high potency sweetener from leaf extract, Glucose, Sucrose
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manchester
High-intensity Interval Exercise, Heart Rate
Acute Physiological and Perceptual Responses to Novel Forms of High-intensity Interval Exercise
Randomised cross-over study seeking to explore the acute physiological and perceptual responses to three novel forms of high-intensity interval training (HIT).
- Conditions
- High-intensity Interval Exercise, Heart Rate, Rating of Perceived Exertion, Blood Pressure
- Trial name
- NCT03359928
- Testing
- Boxing, Stair stepping, Stair climbing
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Teesside University
Caffeine
The Repeatability of the Effect of Caffeine Supplementation on Submaximal Physiological Responses and Cycling Time Trial Performance
Recently, Grgic (2018) discussed the concept of responders and non-responders to caffeine supplementation highlighting the importance of the repeatability of results.
- Trial name
- NCT06935214
- Testing
- Caffeine
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Gene Expression
Neural and Physiological Responses to Real-World Experiences
UCLA researchers looking for healthy individuals (aged 35-50) who have a home computer with internet access, are not pregnant, planning to become pregnant, or currently breastfeeding (if female), to participate in a study…
- Trial name
- NCT01723410
- Testing
- Writing about people, Writing about places, objects
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles