Clinical trials: Physiological Responses
Body Temperature Changes, Heat Stress
Exercise Intensity and Heat Responses in Children and Youth
Little is known about how children and youth regulate body temperature during exercise in the heat compared with young adults, including whether differences in whole-body heat exchange contribute to their responses.
- Conditions
- Body Temperature Changes, Heat Stress, Child Development, Heat
- Trial name
- NCT07781592
- Testing
- Low-Intensity Exercise in the Heat, Moderate-Intensity Exercise in the Heat, Vigorous-Intensity Exercise in the Heat
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Autism, Major Depressive Disorder (MDD)
Investigating the Brain's Physiological Responses in Depression and Autism, Using Transcranial Magnetic Stimulation and Electroencephalography
The goal of this observational study is to investigate the brain physiological responses in depression and autism. The main questions aim to answer are: 1.
- Trial name
- NCT06821646
- Testing
- Positron Emission Tomography (PET), transcranial magnetic stimulation and electroencephalography(TMS-EEG)
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Panic Disorder
Genetic Causes of Panic Disorder
This study will try to identify genes that increase the risk of developing panic disorder-an anxiety disorder characterized by recurrent unexpected panic attacks-and that contribute to the abnormalities associated with it.
- Trial name
- NCT00083265
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- National Institute of Mental Health (NIMH)
Type 2 Diabetes Mellitus (T2DM)
Postprandial Glycemic and Physiological Responses to Walking With a Wearable Hip Exoskeleton in Patients With Type 2 Diabetes
This randomized crossover proof-of-concept study evaluated the effects of walking with a wearable hip exoskeleton on postprandial glycemic and physiological responses in patients with type 2 diabetes.
- Trial name
- Bot-Fit T2D St (NCT07692802)
- Testing
- Bot-Fit Aqua Mode, Bot-Fit Boost Mode, Non-Assisted Walking
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- CHA University
Health Behavior
Different Training (Aerobic, Resistance or Mixed) Physical Programs Affect to Physiological Responses (TRAINING2014)
Background. The cardiovascular and cardiorespiratory coupling (CVCRC), focusing to recognize the synergies of standard or modified physiology that promote healthy.
- Trial name
- TRAINING2014 (NCT02441192)
- Testing
- Training resistance, Training aerobic, Training resistance+aerobic
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
no Conditions
Intake Duration Effects of Blackcurrant on Cardiovascular and Metabolic Responses
Study will examine the metabolic, physiological and cardiovascular changes by intake of New Zealand blackcurrant extract at rest and during moderate-intensity treadmill walking in healthy males.
- Trial name
- NCT05067062
- Testing
- New Zealand blackcurrant extract
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Chichester
Sedentary Behavior, Sedentary Time
Sitting Interruption and Whole-body Cardiovascular Health
There is strong evidence for the association between sedentary behaviors and cardiovascular diseases such as coronary heart disease and stroke.
- Trial name
- SWITCH (NCT05316571)
- Testing
- One 5-Minute Walking Bout Each Hour, One 15-Minute Standing Bout Each Hour, One 5-Minute Walking Bout and One 15-Minute Standing Bout Each Hour
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Essential Hypertension, Aromatherapy
Effects of Aromatherapy in Hypertensive Individuals
Objective: To investigate the effect of aromatherapy on blood pressure and stress response by inhalation and foot massage in individuals with essential hypertension.
- Conditions
- Essential Hypertension, Aromatherapy, Stress, Physiological
- Trial name
- NCT04460300
- Testing
- Aromatherapy-inhalation method, Aromatherapy-foot massage group
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Abant Izzet Baysal University
Sports Performance, Respiratory Muscle Function
Inspiratory Muscle Warm-Up in Combat Athletes
The aim of this study is to investigate the effects of inspiratory muscle warm-up (IMW) on technical performance and physiological responses in combat athletes.
- Conditions
- Sports Performance, Respiratory Muscle Function, Cardiorespiratory Responses
- Trial name
- NCT07481916
- Testing
- POWERbreathe
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Pertussis, Whooping Cough
Study of BPZE1 Intranasal Pertussis Vaccine (Administered Via VaxINator(TM)), Prime + Boost, in Healthy Adults
This study evaluates the safety and immunogenicity of the BPZE1 live attenuated pertussis vaccine, intended to prevent nasopharyngeal colonization and pertussis disease, and compares a single (prime) BPZE1 dose or BPZE1 2-dose…
- Trial name
- NCT03942406
- Testing
- BPZE1 pertussis vaccine and VaxINator(TM) Atomization Device
- Where
- 3 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- ILiAD Biotechnologies
Anxiety, Heart Rate Variability (HRV)
Anxiety and Physiological Responses in Ambulatory Surgery
This study aims to investigate the effects of music intervention on subjective anxiety and physiological indicators, including heart rate, blood pressure, and heart rate variability, in first-time ambulatory surgery patients, and…
- Conditions
- Anxiety, Heart Rate Variability (HRV), Heart Rate, Blood Pressure
- Trial name
- NCT07476820
- Testing
- Self-selected Music intervention, Fixed-music Music intervention
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Da-Yeh University
Fear Pain
Human Behaviors Related to the Expectation of Pain
The conditioned expectation of pain is an important aspect of pain-related disability produced by environments and stimuli associated with a painful injury on the job, although the neuroscience of this expectation is unclear.
- Trial name
- NCT03739645
- Testing
- Skin conductance levels and slopes over time in conditioned fear as metrics.as metrics for anxiety
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Psychological Phenomena and Processes, Nutrition Physiological Phenomena
The Effects of Fiber on Appetite and Digestion Hormones
In this research study, investigators are interested in how certain dietary fibers in the diet affect certain hormones released from your intestine after eating and how these influence your appetite.
- Trial name
- FS (NCT01050101)
- Testing
- No fiber, Low GI high fiber viscous meal, Low GI high fiber non-viscous
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Head and Neck Cancer
The Physiological Response to Routine Head and Neck Cancer Surgery
The main objective of this pilot study is to observe and document the range of changes in the blood concentrations of certain hormones, inflammatory chemicals and immune chemicals in response to the stimulus of Head and Neck…
- Trial name
- NCT01032096
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Dental Anxiety, Music Intervention
Effect of Music on Dental Anxiety and Physiological Responses During Dental Drill and Suction Sounds
Dental anxiety is common and may be triggered or increased by sounds associated with dental treatment, particularly the sound of a dental drill and suction device.
- Trial name
- MUS-DENT (NCT07827118)
- Testing
- Music intervention
- Where
- Pakistan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Stress Response, Multitasking Behavior
Can Cranberry Juice Enhance the Cognition Accuracy and Alleviate Negative Mental Consequences During Multitasking?
This clinical trial aims to investigate the effects of a 70-day consumption of cranberry juice on cognitive and motor accuracy, mental and physiological stress, and stress response in healthy men and women between the ages of 30…
- Conditions
- Stress Response, Multitasking Behavior, Mental Stress, Physiological Stress
- Trial name
- NCT06066619
- Testing
- Cranberry Juice A, Cranberry Juice B
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Florida
Anorexia of Aging, Malnutrition or Risk of Malnutrition
The SAVOR Study: Appetite and Physiological Responses
The study aims to identify key physiological factors that differentiate older adults with healthy appetites from those experiencing appetite decline.
- Trial name
- SAVOR (NCT07636369)
- Testing
- Shredded Chicken Congee
- Where
- Singapore
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Postprandial Glycemic Response, Healthy Adults
Postprandial Glycemic and Physiological Responses to Walking With a Wearable Hip Exoskeleton in Healthy Adults
This randomized crossover proof-of-concept study evaluated the effects of walking with a wearable hip exoskeleton on postprandial glycemic and physiological responses in healthy adults.
- Trial name
- Bot-Fit Health (NCT07695441)
- Testing
- Walking Without Bot-Fit, Bot-Fit Aqua Mode, Bot-Fit Boost Mode
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- CHA University
Healthy
A Phase 1 Study of FZ008-145 in Healthy Subjects.
The study will be conducted in 5 parts: Part A and Part B (single ascending dose [SAD] in solution formulation and tablet respectively), Part D and Part D2 (cold pressor test [CPT] to evaluate pain tolerance following single…
- Trial name
- NCT06685809
- Testing
- FZ008-145 solution, FZ008-145 Tablet
- Where
- Australia
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Guangzhou Fermion Technology Co., LTD
Physiologic Responses to Surprise Events
Shock Factor: Effects of Surprise on Cardiovascular Responses.
This research will determine the breathing, heart rate and other responses to four surprise events. For two events, virtual reality goggles will be used to create a realistic experience of falling out of a boat and rolling out of…
- Trial name
- NCT05664399
- Testing
- Surprise events
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba