Clinical trials: Physiological Responses
Healthy Adult Participants
Multilevel Exercise Response in Rowers
This observational study aims to evaluate multilevel physiological, molecular, metabolic, intestinal, immunological, and psychophysiological responses to rowing-specific exercise in elite rowers.
- Trial name
- NCT07613619
- Testing
- 2000-m rowing ergometer test, 6000-m rowing ergometer test
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Physiological Stress, Heat Stress
Validation of Heat Stress Limit Values for the Athletic Performance
Three male and three female semi-professional athletes, ranging in age from 22 to 27, participated in a study that was done at Lund University in Sweden to examine their physiological responses.
- Conditions
- Physiological Stress, Heat Stress, Sports Injury, Heat Stress, Exertional
- Trial name
- HSL-AP (NCT06084494)
- Testing
- analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe Temperature
- Where
- Pakistan
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of the Punjab
Anorexia Nervosa
A Randomised Controlled Trial on the Networks Integrating Anxiety and Metabolism in Anorexia Nervosa
Anorexia nervosa (AN) is known as the psychiatric disorder with the highest mortality rate as long-term calorie restriction causes medical complications and suicide risk.
- Trial name
- NAMA (NCT06814002)
- Testing
- Meal with 400 kilocalories, Meal without calories
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Umeå University
Military Operational Stress Reaction, Malnutrition (Calorie)
Physiological Response to Protein and Energy-enhanced Food Products During Winter Military Training
Soldiers commonly lose muscle mass during training and combat operations that produce large energy deficits (i.e., calories burned > calories consumed).
- Conditions
- Military Operational Stress Reaction, Malnutrition (Calorie), Weight Loss, Muscle Wasting
- Trial name
- NCT05210205
- Testing
- EAA, Energy Dense, Control
- Where
- Norway
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Heart Failure
Physiological Response to Exercise: Sensor Evaluation at Specified Exertions
Assessment of sensor parameter in patients with heart failure.
- Trial name
- PRE-SENSE (NCT01229137)
- Testing
- SRD-1 conversion
- Where
- 14 sites in United States
- Volunteers
- 71 people
- Sponsor
- Boston Scientific Corporation
Respiratory Muscle Function and Football Performance
Acute Effects of Breathing Resistance During Exercise in Football Players
This randomized crossover study will examine the immediate effects of breathing resistance during exercise in 35 active football players aged 18-30 years.
- Trial name
- NCT07907510
- Testing
- Breathing-Resistance Exercise Mask, No-Mask Exercise
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Obesity, Metabolic Disease
Body Fat Distribution and Fat Metabolism
The primary purpose of the study is to examine the effect of body fat distribution on the physiological response to a dietary fat intervention.
- Trial name
- NCT00475774
- Testing
- Long-chain (C18:2) and medium chain fatty acid (C8 and C10).
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- TNO
Inflammation, Oxidative Stress
Inflammatory Responses After CrossFit and Resistance Trainings in Untrained Subjects
Considering the remarkable increase of the fitness programs, the purpose of this study was to assess and compare the effect of Crossfit (CF) and periodized resistance (RT) trainings on inflammatory/oxidative responses in…
- Conditions
- Inflammation, Oxidative Stress, Plasma Volume, Hormones
- Trial name
- NCT07190924
- Testing
- 12 week training
- Where
- Tunisia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Habil Hamdouni
Healthy Volunteers
Showers and Stress
The study investigates whether repeated exposure to cold showers can improve the ability to cope with and respond to stress. In particular, it examines both the psychophysiological effects of cold showers and the role of…
- Trial name
- S A S (NCT07611422)
- Testing
- Positive expectation about the effects of cold and warm showers, No expectation regarding the exposure to cold water and/or to warm showers
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
PHYSIOLOGICAL PHENOMENA
Importance of Liver Innervation for the Osmopressor Response in Humans
In patients with autonomic dysfunction water drinking elicits a pressor response mediated by sympathetic activation. If any, in healthy subjects there is only a slight increase in blood pressure.
- Trial name
- HEP-Reflex (NCT01237431)
- Testing
- 500ml water intake
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Hannover Medical School
Type 1 Diabetes Mellitus
Physiologic Response to Glucagon at Varying Insulin Levels
The purpose of this research study is to test how different levels of insulin block the effect of glucagon. Insulin is a hormone that lowers blood glucose. Glucagon raises blood glucose.
- Trial name
- NCT01483651
- Testing
- Glucagon, Insulin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Legacy Health System
Acute Physiological Effects of Organic Guayusa Extract
Acute Effects of Organic Guayusa Extract
Guayusa extract is a caffeinated tea leaf unique blend of antioxidants and caffeine. It is marketed as an ingredient that can help support energy and performance with potential health-related benefits.
- Trial name
- NCT05928195
- Testing
- Acute Moderate-Dose Guayusa Extract Supplementation, Acute High-Dose Guayusa Extract Supplementation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Nathaniel Jenkins
Contraception, Iron Deficiencies
Influences of Long-acting Reversible Contraceptives on Iron Status and Physiological Responses to Extreme Environments in Women
Over recent years, military service women have shown increasing interest in utilizing long-acting reversible contraceptives (LARCs; i.e., implants or intrauterine devices, IUDs).
- Trial name
- NCT06909695
- Testing
- Blood volume and environmental testing
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Esophageal Neoplasms, Stomach Neoplasms
Food Intake and Gut Hormones in Patients Who Have Undergone Upper Gastrointestinal Surgery for Cancer
Improvements to treatment strategies for patients upper gastrointestinal cancers have produced an increasing population of people who remain free from disease recurrence in the long term.
- Conditions
- Esophageal Neoplasms, Stomach Neoplasms, Weight Loss, Malnutrition
- Trial name
- NCT02385617
- Testing
- Octreotide
- Where
- 2 sites in Ireland, Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- St. James's Hospital, Ireland
Other Gastrointestinal Disorders, Cramp, Abdominal
The Influence of Different Mood States and Emotions on the Physiologic, Metabolic, and Perceptual Responses to Feeding Before Exercise
Many athletes anecdotally report modifying their nutritional intake before competition in order to avoid gut problems, but no studies have evaluated whether emotional state impacts tolerance to pre-exercise feeding.
- Trial name
- NCT05217589
- Testing
- Funny/Amusing Video Clips, Horror/Scary Video Clips, Thrilling/Suspenseful Video Clips
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
Effects of Walking and Cycling on Serum Physiological Biomarkers
Evaluation of Serum Autophagic Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Individuals
Physical exercise (walking and cycling) is a potent physiological stimulus that simultaneously alters energy balance, mechanical loading, and metabolic demands in the organism.
- Trial name
- NCT07536659
- Testing
- WALKİNG
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Older Adults (60 - 85 Years Old), Aging
Functional and Physiological Responses to Multicomponent Exercise in Older Adults
This study will examine functional and physiological responses to a 12-week multicomponent exercise program in community-dwelling older adults.
- Conditions
- Older Adults (60 - 85 Years Old), Aging, Functional Capacity, Heart Rate Variability (HRV)
- Trial name
- NCT07702227
- Testing
- Multicomponent Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Psychiatric Disorder, Stress Reaction
Real-Time Assessment of Stress and Stress Response
Stress is a complex natural phenomenon, frequently related to a physiological response, including heart rate, heart rate variability, respiratory rate, skin conductance and temperature.
- Conditions
- Psychiatric Disorder, Stress Reaction, Stress, Psychological, Stress, Physiological
- Trial name
- NCT04100213
- Testing
- Trier Social Stress Test
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Psychiatric University Hospital, Zurich
Smoking, Stress
Physiological Responses in Tobacco Chippers
This study will analyze a series of biological and behavioral markers in different populations of smokers. The study groups will differ in their cigarette consumption and level of nicotine dependence.
- Trial name
- NCT01237834
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Exercise Performance
U-LABA/ICS Effects on Exercise Performance, Formoterol
The purpose of the project is to investigate exercise performance in well-trained individuals in a crossover design following varying degrees of bronchodilation/constriction intervention using current standard procedures.
- Trial name
- NCT06105671
- Testing
- Symbicort, Formoterol, Mannitol
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD