Clinical trials: Physiological Responses
Thermoregulation
Physiological Responses to Heat Stress During High-risk Events
Exertional heat stroke (EHS) affects ~500 Military Personnel and over 100 Soldiers every year, and it is believed that these numbers are underreported.
- Trial name
- NCT06907225
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Sleep, Newborn
Effects of Music-Based Interventions on Sleep Patterns and Physiological Responses in Premature Newborns: A Systematic Review and Meta-Analysis
Sleep in the neonatal period is a fundamental biological requirement for regulating growth, neurodevelopment, and the immune system.
- Trial name
- NCT07127419
- Volunteers
- 1,415 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Critical Illness, Pain
Soap-and-Water Bed Bath Versus Disposable Wipe Bath in the Same ICU Patients
Bed bathing is a routine nursing procedure in the intensive care unit (ICU). In the study units, every patient routinely receives both a traditional bed bath with warm water and soap (every 10 days) and a bath with pre-packaged…
- Conditions
- Critical Illness, Pain, Procedural Anxiety
- Trial name
- YBU-BANYO (NCT07919912)
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Sinop Atatürk State Hospital
Exercise Training Adaptation
Physiological and Molecular Adaptations to Different Training Modalities in National-level Kayak Athletes
This interventional study evaluated physiological, molecular, and performance adaptations to different high-intensity training modalities in national-level kayak athletes.
- Trial name
- NCT07864012
- Testing
- High-Intensity Interval Training, Sprint Interval Training, Combined High-Intensity and Continuous Training
- Where
- Greece
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Healthy, Caffeine
Effects of Variations in Caffeinated Beverages on Well-being
This study will evaluate post-beverage subjective caffeine responses and physiological responses to caffeinated beverage variations in generally healthy adults.
- Conditions
- Healthy, Caffeine, Beverage Intake
- Trial name
- NCT07404254
- Testing
- Caffeinated, low sugar beverage, Caffeinated beverage, Control beverage
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- GUAYAKI SUSTAINABLE RAINFOREST PRODUCTS, INC.
Exercise Recovery, Exercise-induced Muscle Damage
Effect of Cordyceps Supplementation Timing on Physiological Responses and Aerobic Adaptation in Athletes
Athletes frequently perform high-intensity exercise to improve physical performance and aerobic capacity. However, such training can induce exercise-induced muscle damage, oxidative stress, and inflammatory responses that may…
- Conditions
- Exercise Recovery, Exercise-induced Muscle Damage, Oxidative Stress, Sports Performance
- Trial name
- CORD-RECOV (NCT07664345)
- Testing
- Pre-Exercise Cordyceps Sinensis, Post-Exercise Cordyceps Sinensis
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Surabaya State University
Erectile Dysfunction, Benign Prostatic Hyperplasia
Efficacy, Safety and Dose-response of Udenafil in Patients With Benign Prostatic Hyperplasia and Erectile Dysfunction
The purpose of this study is to evaluate the efficacy, dose-response and safety of udenafil 25 mg, 50 mg and 75 mg every day (q.d.) for 12 weeks in the treatment of lower urinary tract symptoms (LUTS) associated with benign…
- Trial name
- NCT01967251
- Testing
- Udenafil
- Where
- 8 sites in Mexico
- Sponsor
- Takeda
Alzheimer Disease
Dynamic Response to Probiotics in Context of Alzheimer Disease: a Proof-of-concept Study
proof-of-concept study to adequately design a larger trial to investigate the effect of supplementation of a probiotic (SLAB51) on AD biomarker.
- Trial name
- HISTEPPA (NCT05521477)
- Testing
- SLAB51
- Where
- Switzerland
- Volunteers
- 3 people
- Sponsor
- University Hospital, Geneva
Effects of GAHT, on Skeletal Muscle in TGD
Metabolic and Physiologic Responses to Hormone Therapy in Transgender and Gender Diverse People
The primary purpose of this research is to determine how gender affirming hormone therapy affects muscle physiology.
- Trial name
- NCT06083766
- Testing
- hormone therapy
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Erectile Dysfunction
Study to Evaluate Hemodynamic Response to to a Sublingual Dose of Glyceryl Trinitrate in Subjects Receiving TA-1790, Sildenafil Citrate, and Placebo
The objective of this study is to evaluate the hemodynamic response to a sublingual dose of glyceryl trinitrate in subjects receiving oral TA-1790, sildenafil citrate, and placebo.
- Trial name
- NCT01616485
- Testing
- TA-1790, Sildenafil citrate, Nitrostat
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Adrenal Insufficiency
Physiological Response of Cortisol to Cardiac Catheterization
Cortisol is essential for survival. The importance of cortisol response is most apparent in patients with partial or complete deficiency of glucocorticoids during stressful events such as illness or surgery.
- Trial name
- NCT01822847
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Creighton University
Erectile Dysfunction
Combined Effect of Continuous and Interval in Addition to Tadalafil Drug on Erectile Dysfunction
Erectile dysfunction (ED) is the persistent inability to attain and maintain a sufficient erection to permit satisfactory sexual performance.
- Trial name
- NCT04623840
- Testing
- Tadalafil 5Mg Tab + continuous and interval exercise, Tadalafil 5Mg Tab
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Facial Nerve Palsy, Bell's Palsy
Electro Physiological Responses to Kabat Motor Control Re-education on Bell's Palsy: A Randomized Controlled Study
To investigate the Effect of Kabat motor control re-education therapy on facial nerve Electro physiological responses and facial muscles function in bell's palsy.
- Trial name
- NCT04894513
- Testing
- Kabat motor control re-education therapy, conventional selected program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Lama Saad El-Din Mahmoud
Heart Failure, Cardiomyopathies
Multimodal Physiologic State Intelligence Study
The OMNIPHYS study will investigate whether multimodal ultrasound and other routinely collected clinical and physiologic data can be combined with artificial intelligence to characterize changes in a person's physiologic state…
- Conditions
- Heart Failure, Cardiomyopathies, Pulmonary Hypertension, Myocarditis; Acute or Subacute
- Trial name
- OMNIPHYS (NCT07814118)
- Testing
- OMNIPHYS Multimodal Ultrasound Imaging System
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Cognitive Change, Stress, Psychological
Acute and Chronic Effects of Avena Sativa on Cognition and Stress
The flavanoid and terpene phytochemicals present in wild green oat interact with multiple mechanisms relevant to brain function; including those which would modulate cognition and stress.
- Conditions
- Cognitive Change, Stress, Psychological, Mood
- Trial name
- NCT03689348
- Testing
- Avena sativa
- Where
- United Kingdom
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Obesity
Mechanisms Underlying Postoperative Insulin Resistance and Inflammation
Having an operation places an enormous burden on the body, leading to the development of inflammation and so called 'insulin resistance'.
- Trial name
- NCT01470534
- Testing
- carbohydrate drink, Muscle biopsy, Blood sampling
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University of Nottingham
Physiological Stress Responses to Standardises Stress Situations, Psychological Responses to Standardised Stress Situations
Effects of Contact to Dogs During Stressful Situations
The investigators will conduct an experimental study comparing responses of healthy participants in two test situations where they are subjected to mild stress.
- Conditions
- Physiological Stress Responses to Standardises Stress Situations, Psychological Responses to Standardised Stress Situations, Behavioural Responses to Standardised Stress Situations
- Trial name
- NCT04866173
- Testing
- Dog, No Dog
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Healthy, Caffeine
Effects of Caffeinated Beverages on Well-being
This study will evaluate post-beverage subjective caffeine responses and physiological responses to caffeinated beverages in generally healthy adults.
- Conditions
- Healthy, Caffeine, Beverage Intake
- Trial name
- NCT07357818
- Testing
- Participants' typical caffeinated beverage, Test caffeinated beverage
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- GUAYAKI SUSTAINABLE RAINFOREST PRODUCTS, INC.
Normobaric Hypoxia, Hypoventilation
"Living Low - Training High" Methods and Physiological Responses in Well-trained Swimmers
To overcome the lack of knowledge regarding the impact of different "living low, training high" methods on swimming performance, a 4-week intervention will be carried out to determine and compare the effects of three Repeated…
- Conditions
- Normobaric Hypoxia, Hypoventilation, Normoxia
- Trial name
- NCT06253039
- Testing
- Repeated sprint
- Where
- Portugal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Vascular Disease, Peripheral, Physical Inactivity
Inter-individual Physiological Response to a Training and Detraining Period in Cardiometabolic Risk Factors Subjects
Background: Although exercise training is a well described therapy for some cardiometabolic diseases such as obesity, type 2 diabetes, arterial hypertension, and metabolic syndrome, there is scarcity of knowledge about the…
- Conditions
- Vascular Disease, Peripheral, Physical Inactivity, Arterial Hypertension, Endothelial Dysfunction
- Trial name
- VASCU-HEALTH (NCT05710653)
- Testing
- Exercise training intervention
- Where
- Chile
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cristian Alvarez