Clinical trials: Physiological Responses
Exercise
Gene-Exercise Interactions in Athletes
Athlete status is a heritable trait that could be explained with a number of potentially important DNA polymorphisms contributing to predisposition to success in certain types of sport.
- Trial name
- GE-EX (NCT03279380)
- Testing
- SNP, High Intensity Interval Training (HIIT), Low Intensity Continuous Training
- Where
- Slovenia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Acute Stress Reaction
Explorative Open Label Study of Efficacy Profile of Neurexan® in Experimental Acute Stress Setting in Healthy Subjects
The purpose of this study is to explore the efficacy of acutely dosed Neurexan using an experimental stress test called the Trier Social Stress Test
- Trial name
- NEUPRO-OL (NCT01703832)
- Testing
- Neurexan®
- Where
- 2 sites in Germany
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Biologische Heilmittel Heel GmbH
Septic Shock
The Effect of Rapid Fluid Challenge Under Pulmonary Artery Catheter Monitoring on Physiological Indexes of Patients With Septic Shock
Fluid challenge is often carried out in septic shock patients. Its responsiveness usually requires invasive monitoring. The pulmonary artery catheter(PAC) is the most effective means of monitoring.To use non-invasive methods is…
- Trial name
- NCT03661268
- Testing
- fluid chanllenge
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chengdu Fifth People's Hospital
Cognitive Change, Stress
Acute Effects of Mango Leaf Extract (Zynamite®) on Cognitive Function, Mood and Stress
This study aims to assess the effects of a single dose of Zynamite® on performance across a number of cognitive domains (attention, working memory, episodic memory, executive function), as well as during a period of cognitively…
- Trial name
- MLE-ZYN (NCT04299217)
- Testing
- Zynamite®
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Caffeine, Alcohol
Investigating the Effect of Caffeine and Alcohol on Pupil Dynamics
The goal of this study is to understand how caffeine and alcohol affect the ocular and physiological systems, especially how the pupil (the aperture in the colored part of the eye) responds to light.
- Conditions
- Caffeine, Alcohol, Pupillary Response, Eye Movements
- Trial name
- PAC (NCT07625358)
- Testing
- Caffeine administration, Alcohol (Ethanol)
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Healthy Aging
The Effects of Post Aerobic Exercise Hot Water Immersion on Physiological and Perceptual Responses in Physically Inactive Middle-aged Adults
This study will investigate the effects of post moderate intensity aerobic exercise hot water immersion on physiological and perceptual responses in physically inactive middle-aged adults when compared to moderate intensity…
- Trial name
- NCT05035004
- Testing
- Post exercise hot water immersion, Exercise, Hot water immersion
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Coventry University
Schizophrenia, Schizoaffective Disorder
Therapeutic Improvement in People With Schizophrenia Undergoing tACS/CBTp (Transcranial Alternating Current Stimulation Applied Pre-cognitive Behavioral Therapy for Psychosis) Associated to Usual Medication Regimen
The investigators are proposing a new, non-invasive therapeutic model using transcranial alternative current stimulation (tACS), to augment cognitive behavioral therapy for psychosis (CBTp) efficacy in individuals with…
- Trial name
- tACS/CBTpSZ (NCT06889025)
- Testing
- Experimental: tASC/CBTp: gamma band electric stimulation for 20 minutes at the beginning of the CBTp session
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Felicia Iftene
Copd, Chronic Hypoxemic Respiratory Failure
Different Modalities of Exercise Training in COPD With Chronic Respiratory Failure (CRF)
Advanced Chronic Obstructive Pulmonary Disease (COPD) is a condition with a negative prognosis that causes symptoms such as wheezing and fatigue that dramatically reduce the quality of life of the person with the disease.
- Trial name
- NCT04201548
- Testing
- Endurance Training, Long High Intensity Interval Training, Short High Intensity Interval Training
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Healthy, Athletes
An Initial Investigation Into the Effects of β-Alanine on Performance and Physiological Responses During Simulated Wrestling Matches
This research aims to investigate the effects of beta-alanine (BA) supplementation on simulated 2-day freestyle wrestling performance, as well as on exercise-induced muscle fatigue and oxidative stress in wrestlers.
- Trial name
- NCT07641907
- Testing
- Beta-Alanine (Beta-Alanine trial)
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Eating Behaviour, Obesity
Calorie Anticipation and Food Intake
The regulation of our food intake is on the short-term guided by appetite and satiety signals generated by the sight and consumption of food.
- Trial name
- NCT01680315
- Testing
- low calorie yogurt, high calorie yogurt
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Uppsala University
GERD
Correlates of GERD Symptom Severity
This is a pilot study measuring physiologic and behavioral correlates of symptom severity in adult patients with gastroesophageal reflux disease (GERD).
- Trial name
- NCT03020550
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Massachusetts General Hospital
Monitoring, Physiologic, Intraoperative Neurophysiological Monitoring
Analyzing the Noxious Autonomic Response During Shoulder Arthroscope Surgery
To record the digital data from monitoring instruments (standard patient monitor) containing cardiovascular system information, and from depth-of-anesthesia monitoring modules (Bispectral index, Entropy module, Surgical…
- Conditions
- Monitoring, Physiologic, Intraoperative Neurophysiological Monitoring, Anesthesia and Analgesia, Arthroscopy
- Trial name
- NCT03688529
- Volunteers
- 40 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Physiological Responses, Sleep Disorders, Circadian Rhythm
Effect of Owning a Service Dog on Military Veterans With PTSD
The study aims to investigate the effects of a service dog on military veterans with post traumatic stress syndrome (PTSD). The investigators will use non-invasive measures of the physiological responses, data obtained via dairy…
- Conditions
- Physiological Responses, Sleep Disorders, Circadian Rhythm, Stress, Emotional
- Trial name
- NCT05208008
- Testing
- With service dog
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Erectile Dysfunction
Stress Management Using an App to Improve Response With PDE5 Inhibitors in Men With Erectile Dysfunction.
The aim of this study is to determine if patients with ED taking PDE5 inhibitors (e.g. Viagra, CIalis, Levitra, Stendra) and experiencing performance anxiety will benefit using a user-friendly stress reducing phone app, Serenita.
- Trial name
- NCT02757807
- Testing
- Utilization of Serenita for Relaxation
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eco Fusion
Coronary Artery Disease (CAD)
Hypoxia Pre-conditioning and Mountain Sport
Mountain sport activities as for example hiking or skiing may involve the risk of adverse health events especially in older people not accustomed to the specific mountain sport at altitude or people with pre-existing health…
- Trial name
- Hyx-PRE-Spo (NCT04725539)
- Testing
- hypoxic exposure
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- Institute of Mountain Emergency Medicine
Physiological Stress, Psychological Stress
The Effect of the Duty Loading on the Stress Response of Physician
The investigators will study in the possibility of cardiovascular disease, caused by the duty loading, of physician of internal medicine.
- Trial name
- NCT01367379
- Testing
- 24 hour EKG and blood pressure monitor, Blood and urine sampling
- Where
- Taiwan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Running, Motivation for Physical Activity
Study of the Psychological, Physiological and Biomechanical Responses to Trail Running in a Hot, Humid Environment
The determinants of trail performance have been extensively studied, and the results have revealed the significant influence of physiological, psychological and biomechanical parameters.
- Conditions
- Running, Motivation for Physical Activity, Sport Physiology
- Trial name
- RP2B-Trail (NCT07831109)
- Testing
- Trail running of 28km and 2580m vertical drop
- Where
- Reunion
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Inflammation
Effects of Dietary Supplements on Response to Air Pollution
This study will determine if a comprehensive antioxidant/anti-inflammatory dietary supplement pack can offer protection against a decline in lung function and increase in inflammation and oxidative stress following acute exposure…
- Trial name
- NCT01488656
- Testing
- Antioxidant, anti-inflammatory dietary supplement
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Utah State University
Wellbeing
Blue Light Emergency Services Wellbeing Feasibility Study
Emergency Service teams operate in some of the most challenging workplaces and experience higher rates of mental ill health than the general population.
- Trial name
- NCT04749966
- Testing
- This is an observational study, there are no interventions
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Anglia Ruskin University
Exercise Performance, Aerobic Capacity
Effects of Small-Sided Games Versus Sprint Interval Running on Aerobic Capacity and Training Load in Elite Football
Purpose of the Study: This study aimed to compare the physiological and performance-related effects of two different training methods in elite football players: supramaximal interval running (SIR) and small-sided games (SSG).
- Trial name
- SIRvsSSG2023 (NCT07132294)
- Testing
- Exercise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University