Clinical trials: Physiology
Youth Volleyball, Sports Performance
Comparative Effects of High-Intensity Interval and Functional Training on Performance Outcomes in Adolescent Female Volleyball Players
Background Volleyball requires repeated explosive actions, agility, and technical precision, demanding contributions from both aerobic and anaerobic energy systems.
- Conditions
- Youth Volleyball, Sports Performance, Neuromuscular Function, Aerobic Capacity
- Trial name
- NCT07181031
- Testing
- High-Intensity Interval Training (HIIT), High-Intensity Functional Training (HIFT)
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Duvenciler Anadolu Lİsesi
Constipation, Gastrointestinal Dysfunction
Effect of Polydextrose on Fecal Bulk and Bowel Function in Mildly Constipated Subjects
Polydextrose (PDX) (8-30g/day) has been reported to increase faecal bulk and consistency, leading to easier stool passage in healthy subjects.
- Trial name
- NCT05309837
- Testing
- Polydextrose
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Tate & Lyle
Chronic Kidney Diseases, Metabolic Syndrome
Theory-based Health Behaviour Change Intervention in Patients of Metabolic Syndrome With Chronic Kidney Disease
The pilot study will adopt a 2-arm, pretest-posttest, and assessor-blind randomized controlled trial design to examine the feasibility and acceptability of a theory-based health behaviour change intervention and examine its…
- Trial name
- NCT06527768
- Testing
- Theory-based health behaviour change interventio
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Endurance Exercise, Exercise Physiology
Comparison of Training Intensity Distribution Models in Recreational Distance Runners
This study aims to compare the effects of three different training intensity distribution (TID) models-polarized, threshold, and pyramidal-on physiological and performance adaptations in recreational distance runners.
- Conditions
- Endurance Exercise, Exercise Physiology, Running Performance
- Trial name
- NCT07565168
- Testing
- Polarided training intensity distribution, Threshold Training Intensity Distribution, Pyramidal Training Intensity Distribution
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Sexual Dysfunction, Physiological
Effects of Lepidium Meyenii Walp on Sexual Function in Postmenopausal Women
Objective: To study the effects of Lepidium Meyenii in sexual function of postmenopausal women. Method: It will be held a clinical, prospective, randomized, double-blind, placebo-controlled study with 144 postmenopausal women…
- Trial name
- maca (NCT02624648)
- Testing
- The Female Sexual Function Index (FSFI), The Female Intervention Efficacy Index (FIEI), The Beck Depression Inventory II
- Where
- Brazil
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Physical Activity, Mental Health Wellness 1
Physical Exercise for Education ('Fit to Study')
Neuroscience evidence suggests that physical exercise can influence brain function and structure, both immediately and in the long-term.
- Conditions
- Physical Activity, Mental Health Wellness 1, Cognitive Function 1, Social, Academic Attainment
- Trial name
- FTS (NCT03286725)
- Testing
- Physical Education (PE) Programme
- Where
- United Kingdom
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Cognitive Decline, Cognitive Dysfunction
Brain Vascular and Neurocognitive Health
The overall research objective of this proposal is to determine the acute and chronic impact of transcranial photobiomodulation on indices of cerebral vascular health and neurocognitive function.
- Conditions
- Cognitive Decline, Cognitive Dysfunction, Alzheimer Disease, Vascular Disease, Peripheral
- Trial name
- NCT06497413
- Testing
- Transcranial Photobiomodulation, Transcranial Photobiomodulation helmet (Neuradiant 1070 Plus) with no light administered
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Brain Function
Modulation of Spontaneous Cortical Activity by tDCS: BRAIN Initiative I
This study will determine whether transcranial direct current stimulation (tDCS) can be used alter the amplitude of spontaneous neural activity, and thereby modulate cognitive function in healthy adults
- Trial name
- NCT03672747
- Testing
- transcranial direct-current stimulation (tDCS)
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Proprioceptive Disorders
The Acute Effect of Foam Rolling on Elbow Joint Sensorimotor Function
The purpose of this study is to investigate the acute effects of foam rolling on elbow joint sensorimotor function with healthy participants . Study group will receive foam rolling exercise.
- Trial name
- NCT03516149
- Testing
- Foam Rolling Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Healthy Subjects
Effects of Recombinant Human Erythropoietin on Platelet Function in Healthy Subjects
The purpose of this study is to see if a naturally-occurring hormone called erythropoietin changes the action of platelets in the blood.
- Trial name
- NCT00368238
- Testing
- Recombinant human erythropoietin alfa (drug), Aspirin (drug), Clopidogrel (drug)
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Yale University
Diabetes Type 2
Exercise Study on Cardiac Function in Patients With Diabetes Mellitus Type 2 and Diastolic Dysfunction
The aim of the study is to compare the effects of aerobic interval training and the IDF recommendations on physical activity on cardiac function and CV risk factors in patients with diabetes.
- Trial name
- NCT01206725
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Normal Physiology
Sensory Afferents for Deep Pressure Sensation
Background: Much is known about how people perceive light touch, temperature, and pain. But less is known about how deep pressure is perceived. Deep pressure is an important part of many touch therapies, like massage therapy.
- Trial name
- NCT03937778
- Testing
- Deep pressure block
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
HIV
The Effect of Hyperbilirubinemia on CV Disease, Neurocog Function and Renal Function
Use of some protease inhibitors is associated with elevations of a blood pigment called bilirubin. This may occasionally lead to yellowing of the eyes (scleral icterus) or jaundice, but in the general population bilirubin…
- Trial name
- SSAT044 (NCT01475240)
- Where
- United Kingdom
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- St Stephens Aids Trust
Hepatic Impairment
Pharmacokinetics (PK) of 20 mg Teduglutide in Participants With Moderately Impaired Hepatic Function Compared to Healthy Participants
This is a study to compare the pharmacokinetic profile of teduglutide in healthy participants with normal hepatic function with participants who have moderate hepatic impairment.
- Trial name
- NCT00819468
- Testing
- Teduglutide
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Shire
Healthy Subjects
Bioavailability and Pharmacokinetic Parameters of Watermelon (Rind, Flesh and Seeds) Polyphenols
The primary objectives of the study are outlined below: 1. To investigate the relative bioavailability and absorption/kinetic profile of polyphenols after consumption of watermelon rind, flesh and seeds, respectively in an acute…
- Trial name
- WM (NCT03365960)
- Testing
- Watermelon Rind, Watermelon Flesh, Watermelon Seeds
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Attention, Mood
A Study to Assess the Synergistic Effects of a Cranberry Beverage on Cognitive Function
This study aims to determine the effect short-term dosing (7 days) of a placebo beverage, cranberry juice, cranberry juice + lemon balm extract, cranberry juice + tart cherry powder, or cranberry juice + L-theanine or L-theanine…
- Trial name
- NCT05008549
- Testing
- Cranberry Juice Product
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ocean Spray Cranberries, Inc.
HR Vaiability, Aerobic Physical Fitness,Blood Pressure, Blood Sugar Level, Blood HDL, LDL
Aerobic Exercise Training & the Autonomic System In Patients After Myocardial Infarction or Stroke
The purpose of this study is to examine the effect of Aerobic Physical Activity on the function of the Autonomic System in patients after Myocardial Infarction or Stroke.
- Trial name
- NCT00259948
- Testing
- Aerobic exercise training
- Where
- Israel
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Mitochondrial Function
Functional Mitochondrial Analysis PBMCs
The primary goal of this prospective, exploratory, longitudinal, single-centre, cohort study is to assess the stability of the mitochondrial flux in PBMCs over long-term cryopreservation.
- Trial name
- FMAP (NCT06498791)
- Testing
- Venipuncture, Questionnaire
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Stroke
Understanding Motor Function in Stroke Patients and Their Functional Brain Reorganization Using Ultra High-field MRI
The MOTIF-STROKE study is embedded within the BrainSync project, aiming to develop innovative strategies for motor rehabilitation of the upper limb.
- Trial name
- MOTIF-STROKE (NCT07339813)
- Testing
- Functional MRI (fMRI) Acquisition
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Commissariat A L'energie Atomique
Cognitive Function, Preclinical, Chronic Kidney Diseases
Exercise Training and Cognitive Function in Kidney Disease
Chronic kidney disease (CKD), affects over 45% of all individuals over 70 years of age. Patients with moderate CKD have more than a two-fold increased risk of cognitive impairment than those without CKD; furthermore, as many as…
- Conditions
- Cognitive Function, Preclinical, Chronic Kidney Diseases, Older Adults
- Trial name
- NCT03197038
- Testing
- Partially supervised home-based walking exercise, Control
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
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