Clinical trials: Placenta
Pain, Postoperative, Gingival Diseases
Effect of Using Placental Membranes on Healing and Post-op Pain After Gum Surgery
When harvesting autogenous free grafts to treat periodontal conditions (e.g., lack of attached keratinized tissue, ridge defects, and other mucogingival deformities), the hard palate is the preferred donor site.
- Trial name
- NCT04957342
- Testing
- amnion-chorion membrane, Sutures
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
HBV
Prevention for Mother-to-infant Transmission of HBV
In this study, HBV-infected pregnant women were divided into two groups, those who received and those who did not receive hepatitis B immunoglobulin (HBIG) during pregnancy.
- Trial name
- NCT02312531
- Testing
- Hepatitis B immunoglobulin
- Volunteers
- 28 people
- Sponsor
- Xi'an Jiaotong University
Ankylosing Spondylitis
Safety and Efficacy Study of Umbilical Cord/Placenta-Derived Mesenchymal Stem Cells to Treat Ankylosing Spondylitis (AS)
The purpose of this study is to evaluate the safety and efficacy of mesenchymal stem cells (MSCs) derived from human umbilical cord/placenta at a dose of 1.0E+6 MSC/kg in subject for the therapy of Ankylosing spondylitis (AS)
- Trial name
- NCT01420432
- Testing
- Human umbilical cord-derived MSCs
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Shandong University
Gestational Diabetes
The Use of the CPR to Predict Adverse Outcomes in GDM Pregnancies
The cerebro-placental ratio (CPR) is a tool for assessment of fetal wellbeing in the management of the growth restricted fetus. CPR is the ratio of the fetal middle cerebral artery pulsatility index (PI) to the umbilical artery…
- Trial name
- CPR GDM (NCT03072563)
- Where
- Canada
- Volunteers
- 207 people
- Sponsor
- Unity Health Toronto
Placenta Accreta Spectrum, Cesarean Hysterectomy
Early vs Late Bladder Dissection During CS Hysterectomy in Patients With PAS With Bladder Invasion
Thirty-six singleton pregnant women with PAS and bladder invasion; total anterior or anterolateral invasion, who were scheduled for cesarean hysterectomy were randomly assigned into two equal groups Group 1: included 18 pregnant…
- Trial name
- NCT05752513
- Testing
- Late bladder dissection, early bladder dissection
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Placenta Accreta
MRI for the Diagnosis of Placenta Accreta Spectrum
Placenta Accreta Spectrum (PAS) is a disease associated with abnormal placental adhesion and invasion. In recent years, the incidence of PAS has increased significantly, which can cause massive postpartum hemorrhage…
- Trial name
- NCT04151979
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Fetal Growth Restriction, Placenta
Placental Progesterone Membrane Receptors in Fetal Growth Restriction
This prospective observational case-control study aims to compare placental expression levels of progesterone membrane receptors, including PGRMC1, PGRMC2, and PAQR family receptors, among pregnancies affected by impaired fetal…
- Conditions
- Fetal Growth Restriction, Placenta, Progesterone Membrane Receptor, PGRMC1
- Trial name
- NCT07701837
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Samsun University
Pre-eclampsia, Pregnancy, High Risk
Placental Growth Factor Assessment of Women With Suspected Pre-eclampsia
The primary aim is to establish the effectiveness of plasma PlGF measurement in reducing maternal morbidity (with assessment of perinatal safety in parallel) in women presenting with suspected pre-eclampsia prior to 37 weeks'…
- Conditions
- Pre-eclampsia, Pregnancy, High Risk, Pregnancy Complications
- Trial name
- PARROT (NCT02881073)
- Testing
- Maternal plasma PlGF quantification
- Where
- 7 sites in Ireland
- Volunteers
- 2,313 people
- Sponsor
- Irish Centre for Fetal and Neonatal Translational Research
Placenta Accreta Spectrum
Accuracy of Three /Four-dimensional Ultrasound in Diagnosing Placenta Accreta Spectrum
The placenta accreta spectrum (PAS) which includes accreta, increta, and percreta represents a significant obstetric challenge. PAS complicates as many as 1 per 500 pregnancies and this risk is increased with prior cesarean…
- Trial name
- NCT04229953
- Testing
- US scan with 3D/4D VRU software
- Volunteers
- 113 people
- Sponsor
- Hatem AbuHashim
Peyronie's Disease
Evaluate the Safety and Feasibility of Injecting PMD-MSC Into the Penis to Treat the Symptoms of PD
Prospective, open labeled, non-randomized, study to be conducted at a single center. Ten subjects will undergo an injection of Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs) into the penis for the treatment of…
- Trial name
- PMD-MSC-PD-01 (NCT02395029)
- Testing
- Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Melissa Marchand
Pre-Eclampsia, Intrauterine Growth Restriction
PEPPI Study: Identification of Women at Risk for Placental Dysfunction
The main purpose of this study is to evaluate Fetal Medicine Foundation's pre-eclampsia risk calculator using maternal characteristics, first trimester serum placental growth factor (PlGF) and mean arterial pressure (MAP) in a…
- Conditions
- Pre-Eclampsia, Intrauterine Growth Restriction, Polycystic Ovary Syndrome, Iron-deficiency
- Trial name
- NCT06115122
- Testing
- Pre-eclampsia screening program
- Where
- Finland
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Oulu University Hospital
Diabetic Foot, Peripheral Arterial Disease
Hemodynamic Effects of Intramuscular PDA-002 in Subjects Who Have Diabetic Foot Ulcer With Peripheral Arterial Disease
Study PDA-002-DFU-003 is a Phase 2, multicenter, randomized, double blind, placebo-controlled, dose range finding study in subjects who have diabetic foot ulcer (DFU) with peripheral arterial disease (PAD).
- Trial name
- NCT02460081
- Testing
- PDA-002
- Where
- United States
- Sponsor
- Celularity Incorporated
Fetal Growth Retardation
Prediction of Placental Fetal Growth Restriction in High Risk Population (PoPFGR)
This study intends to prospectively enroll high-risk pregnant women to establish a multicenter cohort. By combining maternal basic characteristics, medical history, early pregnancy ultrasound, and biological markers, we aim to…
- Trial name
- NCT06096805
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Bleeding, Placenta Previa
Bakri Balloon in Placenta Previa
The Bakri intrauterine balloon can achieve haemostasis in cases of postpartum haemorrhage, including haemorrhage associated with placenta previa by compressing the lower uterine segment.
- Trial name
- BB-ATS (NCT02694341)
- Testing
- Abdominal traction stitch, Bakri Balloon
- Where
- Egypt
- Sponsor
- Assiut University
Syncytiotrophoblast
From Cytotrophoblast to Syncytiotrophoblast
A deeper understanding of the syncytiotrophoblast development processes and its properties may allow a better understanding of the placenta pathological process for the development of treatment models for the relevant pregnancy…
- Trial name
- NCT02368821
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Pre-Eclampsia
Comparison Between Uterine Artery Doppler and Placental Vascular Indices in Prediction of Preeclampsia
Preeclampsia is a multisystem disorder that can cause considerable maternal and fetal morbidity and mortality. Late preeclampsia (with delivery >34 weeks) is more frequent and less serious than early preeclampsia (with delivery…
- Trial name
- NCT03838887
- Testing
- ultrasound machine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Placental Transfusion
Short-Delay Cord Clamping Compared to Extended- Delay Cord Clamping in Term Neonates That Require Resuscitation.
To determine whether performing extended delayed cord clamping in term neonates that require resuscitation improves early transition as compared to short-delayed cord clamping.
- Trial name
- Term-NRIC (NCT02827409)
- Testing
- Short Delay Cord Clamping, Extended Delay Cord Clamping
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Anup Katheria, M.D.
Urinary Tract Injuries During Caesarean Section for Morbidly Adherent Placenta: Prospective and Retrospective Study
Urinary Tract Injuries During Caesarean Section for Morbidly Adherent Placenta: Prospective and Retrospective Study
M1- evaluates the cases of lower urinary tract injuries during caesarean section with or without hysterectomy in cases with morbid placental adherence in the period between years 2018 and 2021.
- Trial name
- NCT04944355
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Assiut University
Idiopathic Fetal Growth Restriction
Fetal Growth Restriction a Case Control Study
The study aims to investigate the responsible factors that leads to idiopathic fetal growth restriction.
- Trial name
- NCT07025031
- Where
- 2 sites in Malaysia
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Plasmodium Falciparum Malaria, Malaria Diagnosis
Additional Screening With Sensitives RDTs and Malaria
National malaria control strategies in pregnant women relies primarily on effective case management along with the use of long lasting insecticide-treated nets (LLINs)throughout pregnancy and intermittent preventive treatment…
- Trial name
- ASSERMalaria (NCT04147546)
- Testing
- Additional screening using ultra sensitive RDTs, Dihydroartemisinin-piperaquin, Reminders
- Where
- Burkina Faso
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche en Sciences de la Sante, Burkina Faso