Clinical trials: Placenta
Placenta Previa, Placenta Previa Accreta
The Cervix as a Natural Tamponade in Postpartum Hemorrhage Caused by Placenta Previa and Placenta Previa Accreta
Placenta previa and placenta accrete carry significant maternal and fetal morbidity and mortality. Several techniques have been described in the literature for controlling massive bleeding associated with placenta previa cesarean…
- Trial name
- NCT02590484
- Testing
- The cervix as a natural tamponade (cervical inversion)
- Where
- Egypt
- Sponsor
- Minia University
Anemia Pregnancy, Placenta Diseases
The Effect of Anemia in Adolescent and Advanced Age Pregnancies
Anemia by the Centers for Disease Control and Prevention (CDC, 1989); It is defined as hemoglobin (Hb) or hematocrit (Hct) values below the 5th percentile in pregnant women.
- Trial name
- NCT05644964
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Placenta; Retention
Management of Retained Placenta With the "Windmill" Technique of Umbilical Cord Traction
The incidence of leftover placenta after vaginal delivery is between 0.1% and 3.3%, with a maternal mortality of up to 10% reported.
- Trial name
- Windmill (NCT04000321)
- Testing
- Windmill at 30 Minutes, Windmill at 45 Minutes
- Where
- Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Placenta Accreta
Diagnosis and Outcomes of Placental Accretism
The goal of this observational study is to evaluate the diagnostic ability of the main criteria currently adopted for the diagnosis of placenta accreta and to define the maternal outcomes in terms of complications of the…
- Trial name
- NCT06833606
- Where
- 7 sites in Italy
- Volunteers
- 70 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Postpartum Hemorrhage
Emergency Peripartum Hysterectomy: A Prospective Study in Iran
The purpose of this study is to determine the effects of peripartum hysterectomy for maternal hemorrhage.
- Trial name
- NCT01285258
- Testing
- hysterectomy
- Where
- Iran
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Autism
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for Autism
This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells for the treatment of Autism
- Trial name
- NCT05003960
- Testing
- cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells
- Where
- 2 sites in United States, Greece
- Volunteers
- 15 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Pregnancy, Fetal Macrosomia
Correlation Between Placental Thickness in the Second and Third Trimester and Fetal Weight
The aim of this prospective longitudinal study was to investigate the relationship between placental thickness during the second and third trimesters and placental and birth weights.
- Conditions
- Pregnancy, Fetal Macrosomia, Intrauterine Growth Restriction
- Trial name
- NCT02473991
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Malaria, Antepartum
Safety and Immunogenicity of the Placental Malaria Vaccine Candidate PAMVAC Variously Adjuvanted
Despite having developed robust acquired immunity against complications of malaria, women can return to a susceptible state during their first pregnancies and contribute significantly to the burden of severe malaria in highly…
- Trial name
- PAMVAC (NCT02647489)
- Testing
- PAMVAC, Alhydrogel, GLA-SE
- Where
- Benin
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Eclampsia
PIERS and BIS, sFIT:PIGF, Adrenomedullin
Pre-eclampsia, more than being proteinuric gestational hypertension alone, is a state of exaggerated systemic inflammation and remains a leading direct cause of maternal morbidity and mortality worldwide.1 Standardization of…
- Trial name
- BIS2 (NCT02578810)
- Where
- Malaysia
- Volunteers
- 48 people
- Sponsor
- Suez Canal University
Preterm Birth
The Placental Secretome as a Therapeutic Tool to Prevent Inflammation-induced Preterm Birth
Preterm birth complicates 10% of all pregnancies and is the leading cause of perinatal morbidity and mortality worldwide. Intra-amniotic inflammation (IAI) and chorioamnionitis are well-established causes of PTB; however, a…
- Trial name
- PLACENTOMICS (NCT06891508)
- Testing
- Venous blood sampling, Tissues sampling, Umbilical cord blood sampling
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Degenerative Disc Disease, Pain
Efficacy of Intradiscal Injection of Viable Placental Tissue Extract in Subjects With One or Two Level, Symptomatic Lumbar Intervertebral Disc Degeneration
Dr. Parker (the "Investigator") and Semmes Murphey Foundation ("Foundation") are conducting a study of outcomes and safety associated with degenerative discs at Semmes-Murphey Clinic, P.C. ("Semmes-Murphey").
- Trial name
- NCT02379689
- Testing
- Injectable placental tissue extract called BioDGenesis (Active Product)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Semmes-Murphey Foundation
Placenta Accrete Spectrum
The Accuracy Of 3D Color Ultrasonography for Detecting the Degree of Placenta Accreta Spectrum Invasion
To evaluate the correlation between preoperative ultrasound imaging findings by 3D Color Doppler Ultrasound and the intraoperative severity of Placenta Accreta Spectrum (PAS) disorders, in order to assess the diagnostic accuracy…
- Trial name
- NCT07250412
- Testing
- Cesarian section
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Coronary Artery Disease, Hypercholesterolemia
The Role of Atorvastatin on Monocyte Function in Patients With Coronary Artery Disease and Hypercholesterolemia
The aim of this study is to determine, whether an intensified atorvastatin therapy can improve monocyte function in patients with coronary artery disease and hypercholesterolemia.
- Conditions
- Coronary Artery Disease, Hypercholesterolemia, Monocyte Function
- Trial name
- NCT00329069
- Testing
- atorvastatin (drug)
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Thrombosis
Ex Vivo Test of New Stroke Treatment Using Magnetic Nanorobots
Tissue plasminogen activator (tPA) is the FDA approved thrombolytic drug for patients with acute ischemic stroke. While transcatheter endovascular therapy is widely accepted as an effective method for targeted blood vessels via a…
- Trial name
- NCT04644653
- Where
- 2 sites in Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Placenta, Retained
The Effects of Intrauterine Interventions During Placenta Removal on Pain, Perception of Traumatic Birth, and Early Postpartum Health Indicators in Women
A prospective cohort study was conducted with 64 women who had vaginal deliveries at Adana City Training and Research Hospital between October 2023 and May 2024.
- Trial name
- NCT06677294
- Testing
- Placenta remove
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Chronic Kidney Diseases
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for CKD
This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord derived mesenchymal stem cells for the treatment of Chronic Kidney Disease.
- Trial name
- NCT05018845
- Testing
- AlloRx
- Where
- Antigua and Barbuda
- Volunteers
- 20 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
IUD (Intrauterine Device) Malposition, IUD; Complications, Infection or Inflammation
Clinical Outcomes of Post-placental Insertion of Cupper T380A and Multiload 375 Contraceptive Devices During Cesarean Section
Clinical outcomes of post-placental insertion of Cupper T380A and Multiload 375 contraceptive devices during cesarean section
- Trial name
- NCT05624411
- Testing
- CU T380A IUD, multiload 375 IUD
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Pregnancy Related, Physical Activity
Mitochondrial Capacity in Pregnant Women
This Pilot \& Feasibility study will test the hypothesis that pregnant women who are more active will have better functioning mitochondria in vivo (higher ATPmax, via 31P-MRS), which will be positively related to maternal and…
- Trial name
- Mito Moms (NCT03489564)
- Testing
- Active, Sedentary
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Placenta Implantation Site
Relation of Implantation Site to Placental Site
Trans vaginal ultrasound with a partially full bladder will be done at gestational age earlier than 10 weeks to assess the site of intrauterine gestational sac to the endometrial cavity and the distance between the implantation…
- Trial name
- NCT02765984
- Testing
- Transvaginal ultrasound
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Preeclampsia, Preterm Birth
Prediction of Preeclampsia and Other Pregnancy Complications Following Combined Iterative Screening
Preterm birth (PTB), preeclampsia (PE), fetal growth restriction (FGR) and intra-uterine fetal death (IUFD) constitutes the main causes of perinatal morbidity and mortality and are called "Great Obstetrical Syndromes".
- Conditions
- Preeclampsia, Preterm Birth, Fetal Growth Restriction, Intra Uterine Fetal Death
- Trial name
- PREDICTION2 (NCT03067298)
- Where
- Canada
- Volunteers
- 805 people, healthy volunteers welcome
- Sponsor
- Emmanuel Bujold