Clinical trials: Placental Abruption
Abruptio Placentae
Magnesium Sulfate vs Placebo for Placental Abruption
To evaluate the safety and efficacy of magnesium sulfate for preterm suspected abruption.
- Trial name
- NCT00186069
- Testing
- Magnesium Sulfate, Normal Saline
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Haemorrhage
Comparing Blood Loss During Caesarean Section Between Manual Separation of Placenta & Conservative Management
to compare the blood loss during caesarean section between two different methods of separating the placenta after fetal extraction, keeping in mind that most blood loss occurs after placental separation.
- Trial name
- NCT02480556
- Testing
- manual seperation of the placenta, Conservative separation of placenta
- Where
- Egypt
- Volunteers
- 838 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Fetal Growth Restriction (FGR), Preterm Birth
Enhancing Prediction of Adverse Pregnancy Outcomes in Africa Through Partnerships and Innovation
Pregnancy complications such as pre-eclampsia (high blood pressure during pregnancy), poor fetal growth, unexplained stillbirth, and spontaneous preterm birth are major causes of illness and death for mothers and babies in…
- Conditions
- Fetal Growth Restriction (FGR), Preterm Birth, Still Births, Abruptio Placentae
- Trial name
- EPAPOA (NCT07844876)
- Where
- 2 sites in Uganda
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Makerere University
Pregnancy Related, Trauma
The Use of Fetal Fibronectin to Predict Delivery Due to Abruptio Placenta
The purpose of this study is to determine if the presence of fetal fibronectin in the cervicovaginal secretions of pregnant patients with minor maternal trauma predicts impending preterm delivery due to abruptio placenta.
- Conditions
- Pregnancy Related, Trauma, Abruptio Placentae
- Trial name
- NCT01279369
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Winthrop University Hospital
Placental Abruption, Placenta Diseases
Study on Retroplacental Hematomas in Finistère
Cases with placental abruption will be identified by interrogation of two databases of Brest University Hospital between January 2013 and December 2018. First trimester PAPPA and bhCG levels will be recorded.
- Trial name
- HEMOPLACENTA (NCT04168606)
- Where
- France
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
High Risk Pregnancy
Impact of the NO-donor Pentaerythrithyltetrantrate on Perinatal Outcome in High-risk Pregnancies
Pregnancies resulting in IUGR and also in preeclampsia are strongly associated with typical underlying placental pathology revealing small placentas and maldevelopment of the decidual blood vessels, suggesting under-perfusion…
- Trial name
- NCT01355822
- Testing
- PETN
- Where
- Germany
- Volunteers
- 111 people
- Sponsor
- University of Jena
Abruptio Placentae
Plasma Concentration of Biological Markers in Placental Abruption
This will be a prospective study conducted on women with a suspected/confirmed diagnosis of placental abruption. Maternal blood samples will be taken at various points during the peripartum period.
- Trial name
- NCT03782168
- Testing
- There is no other intervention, only clinical treatment.
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Arkansas
Placenta Abruptio
Effect of Placenta Delivery Method on Pain, Bleeding and Comfort
The aim of this thesis is to examine the effect of the placenta delivery method on women's postpartum pain, bleeding and comfort. It is a randomized controlled experimental study.
- Trial name
- NCT06413186
- Testing
- Uteratonic administration, cord clamping, delivery of the placenta
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Preeclampsia
Low Dose Aspirin for the Prevention of Preeclampsia
Preeclampsia is one of the three leading causes of maternal morbidity and mortality all over the world. The use of low dose aspirin has been mentioned in several studies with promising results.
- Trial name
- NCT01890005
- Testing
- Aspirin
- Where
- Panama
- Volunteers
- 476 people
- Sponsor
- Saint Thomas Hospital, Panama
Superficial Injuries Involving Head With Neck
The Relationship Between Isolated Head Trauma During Pregnancy and Preterm Birth
Pregnant patients who presented to the Emergency Department of Şanlıurfa Training and Research Hospital with isolated head trauma due between January 2018 and January 2024 were included in the study and followed up with until the…
- Trial name
- PB (NCT06685549)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sanliurfa Education and Research Hospital
Covid19, Pregnancy Complications
Spanish Registry of Pregnant Women With COVID-19
Study title Spanish Registry of Pregnant Women with COVID-19 Protocol number and version Number 55/20. Version V8. Sponsors This registry is a project promoted by Dr.
- Conditions
- Covid19, Pregnancy Complications, Premature Rupture of Membrane, Abruptio Placentae
- Trial name
- OBS COVID (NCT04558996)
- Where
- Spain
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Puerta de Hierro University Hospital
Pregnancy Complications, Preeclampsia
Severe Pregnancy Complications Are Associated With Elevated Factor VIII Plasma Activity
Congenital and acquired thrombophilia were identified as risk factors for thrombosis in systemic vessels.Thrombophilias have also been recently found to be associated with preeclampsia, intrauterine fetal growth restriction…
- Conditions
- Pregnancy Complications, Preeclampsia, Placental Abruption, Intrauterine Fetal Growth Restriction
- Trial name
- NCT00573118
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Preeclampsia
Prevention of Maternal and Perinatal Complications by Enoxaparin in Women With Previous Severe Preeclampsia
Preeclampsia (PE) complicates 2-8% of pregnancies. It is associated with an increased risk of adverse maternal (death, eclampsia, abruptio placenta, HELLP syndrome) and perinatal (perinatal death, growth restriction, prematurity)…
- Trial name
- HEPEPE (NCT00986765)
- Testing
- Lovenox® (enoxaparin), Aspegic ® (Aspirin)
- Where
- France
- Volunteers
- 257 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Preterm Birth, Low Birth Weight
Perinatal Conditions Influencing Morbidity, Mortality, and Medical Care in Newborns
This study focuses on understanding the conditions that affect newborn health and survival from pregnancy to the first weeks of life at the Isidro Ayora Hospital.
- Conditions
- Preterm Birth, Low Birth Weight, Intrauterine Growth Restriction (IUGR), Perinatal Asphyxia
- Trial name
- UCE (NCT06653374)
- Testing
- Infant, Premature
- Where
- Ecuador
- Volunteers
- 26,000 people
- Sponsor
- HOSPITAL GINECO OBSTETRICO ISIDRO AYORA
No Placental Abruption, No Hemorrhage
Proof of Concept Study of a Sucker Hemostatic Intra Uterine in Postpartum Hemorrhage After Abruptio Placenta Assisted
The postpartum hemorrhage (PPH) is the major complication of the delivery. In clinical practice, if after giving birth, the placenta is not expelled naturally, an active management should be triggered.
- Trial name
- HEMOGYN (NCT01589744)
- Testing
- Suction cup Hemostatic Intra-Uterine, device not marked CE (not marketed)
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- AdministrateurCIC
Primiparity (First-Time Mothers), Breastfeeding
The Effect of Music Play and Stress Ball Application on Placental Separation Time, Episious Pain and Breastfeeding Success
Although the female body and fetus are physiologically equipped to carry out the birthing process, the increasing medical interventions in the birthing process today are pushing women into the background during labor.
- Conditions
- Primiparity (First-Time Mothers), Breastfeeding, Episiotomy, Labour
- Trial name
- NCT07706881
- Testing
- music performance, stress ball squeezing, music listening and stress ball squeezing
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Bitlis Eren University
Pre-Eclampsia, HELLP Syndrome
Evaluation of the Serum Markers sFLt1 and PlGF for the Prediction of the Complications of the Placental Vascular Pathologies in the 3rd Quarter of the Pregnancy.
The pre-eclampsia is a frequent pathology, concerning approximately 5 % of the pregnancies.The pre-eclampsia can evolve into severe maternal and\or foetal complications and is a major cause of mortality.
- Conditions
- Pre-Eclampsia, HELLP Syndrome, Fetal Death, Eclampsia
- Trial name
- PRECOPE (NCT03455387)
- Testing
- sampling of the serum marker sFlt1 and PlGF
- Where
- 7 sites in France
- Volunteers
- 233 people
- Sponsor
- Centre Hospitalier Metropole Savoie
Pre-Eclampsia, Fetal Growth Retardation
Doppler and Biological Second Trimester Placental Insufficiency Screening
To assess the role of uterine artery and maternal serum leptin and lipids and their combination in screening for pre-eclampsia and small-for-gestational-age (SGA) fetuses at 20-24 weeks of gestation
- Conditions
- Pre-Eclampsia, Fetal Growth Retardation, Placental Insufficiency
- Trial name
- ARTULEP (NCT00465634)
- Where
- France
- Volunteers
- 235 people
- Sponsor
- University Hospital, Tours
Fetal Demise, Fetal Growth Restriction
Dose Adjusting Enoxaparin Thromboprophylaxis Dosage According to Anti-factor Xa Plasma Levels Improve Pregnancy Outcome
The risk of venous thromboembolism increases in pregnancy. Thrombophilia whether genetic or acquired, is a hypercoagulable disorder that may increase the risk of venous thromboembolic events.
- Conditions
- Fetal Demise, Fetal Growth Restriction, Preeclampsia, Abruptio Placentae
- Trial name
- NCT01068795
- Testing
- enoxaparin
- Where
- Israel
- Volunteers
- 144 people
- Sponsor
- HaEmek Medical Center, Israel
Abruptio Placentae; Affecting Fetus or Newborn
Normotensive and Hypertensive Placental Abruptions
Placental abruption is a significant cause of both maternal morbidity and neonatal morbidity and mortality. Most abruptions accept to be related to a chronic placental disease process.
- Trial name
- NCT04449601
- Testing
- clinical assesment
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Hatice Akkaya