Clinical trials: Planning
Stroke
Clinical Plan of Ischemic Stroke
Stroke is the main cause of adult health damage. 20% of stroke survivors need institutional care after 3 months, and up to 30% of them have severe or permanent disability.
- Trial name
- NCT04953663
- Testing
- it-hMSC
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Head and Neck Cancer
MRI and PET-CT for Radiotherapy Planning for Head and Neck Cancer
Radiotherapy is commonly used to treat advanced cancers of the head and neck, aiming for cure while preserving patients' quality of life including their ability to speak and swallow.
- Trial name
- NCT02273778
- Testing
- MRI Scan, PET-CT Scan, No intervention
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Type 1 Diabetes Mellitus, Type 1 Diabetes Mellitus (T1DM)
Pediatric Insulin Plan Calculator for T1DM Management
This is a multi-centre, prospective, randomized, open-label controlled trial designed to evaluate the effectiveness of a flexible digital insulin dose calculator in children under 12 years of age with Type 1 Diabetes Mellitus…
- Conditions
- Type 1 Diabetes Mellitus, Type 1 Diabetes Mellitus (T1DM), T1DM, T1DM - Type 1 Diabetes Mellitus
- Trial name
- FLEXI-T1D (NCT07427134)
- Testing
- Flexible Digital Insulin Dose Calculator
- Where
- 2 sites in Iraq, Pakistan
- Volunteers
- 440 people
- Sponsor
- Sultan Qaboos University
Suicide Prevention, Suicidal Thoughts
MYPLAN - Effectiveness of a Safety Plan App to Manage Crisis of Persons at Risk of Suicide
Background: Persons with a past episode of self-harm or severe suicidal ideation are at elevated risk of self-harm as well as dying by suicide. It is well established that suicidal ideation fluctuates over time.
- Conditions
- Suicide Prevention, Suicidal Thoughts, Suicide Attempts
- Trial name
- MYPLAN (NCT02877316)
- Testing
- MYPLAN-safety plan as an application for smart phones, safety plan on paper
- Where
- 4 sites in Denmark
- Volunteers
- 546 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Asthma
Asthma in Families Facing Out-of-pocket Requirements With Deductibles
Asthma is one of the most common chronic diseases in the U.S. Despite guidelines, adherence to recommended controller medications is low. Cost is an important barrier to adherence.
- Trial name
- AFFORD (NCT03175536)
- Testing
- HDHP with PDL
- Where
- United States
- Volunteers
- 12,238 people
- Sponsor
- Harvard Pilgrim Health Care
Pancreatic Cancer, Esophageal Cancer
HOPE - A Study to Evaluate the Effect of a Prehabilitation Program on GI Cancer Patients Planning to Undergo Surgery
A one-group prospective cohort study design with measures collected pre- and post-intervention. The primary goal of this study is to evaluate the effect of a multimodal prehabilitation preoperative program on changes in frailty…
- Conditions
- Pancreatic Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- HOPE (NCT03642093)
- Testing
- Nutritional Intervention, Physical Activity Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Siobhan Trotter
Image, Body, Cervix Cancer
A Novel Functional Imaging Technique With FLT-PET/MRI For Staging, Response Assessment and Radiation Treatment Planning in Cervix Cancer
This pilot study aims to monitor early tumour response based on [18F]FLT-PET/MRI scans and to determine the feasibility of personalised radiotherapy to spare active bone marrow areas identified by [18F]FLT-PET/MRI.
- Trial name
- NCT05355558
- Testing
- [18F]FLT-PET/MRI body scan
- Where
- Singapore
- Volunteers
- 15 people
- Sponsor
- National Cancer Centre, Singapore
Chronic Kidney Disease, Chronic Periodontitis, Generalized, Moderate
Dental Intervention Plan for Chronic Kidney Disease Patients Awaiting or With Kidney Transplant
The study aims to understand why dental infections in end-stage kidney patients results in poor outcomes for kidney functions and eventually transplant.
- Trial name
- NCT04020458
- Testing
- dental intervention
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Augusta University
Neuroendocrine Tumors, Neuroendocrine Tumor Grade 1
177Lu-DOTATATE Modified Delivery Based on Individualized Dosimetry
The goal of this study is to learn if individualized dosimetry-based prescribing of Lutetium-177 DOTATATE (Lutathera, Novartis Pharmaceuticals) improves treatment outcomes for adults with unresectable neuroendocrine tumors.
- Conditions
- Neuroendocrine Tumors, Neuroendocrine Tumor Grade 1, Neuroendocrine Tumor Grade 2
- Trial name
- LUMOD-ID (NCT06395402)
- Testing
- Lutetium Lu 177 dotatate therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Iowa
Prostate Cancer
Genistein in Treating Patients With Localized Prostate Cancer Who Are Planning to Undergo Radical Prostatectomy
RATIONALE: Genistein may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth. PURPOSE: Phase II trial to study the effectiveness of genistein in treating patients with localized prostate…
- Trial name
- NCT00058266
- Testing
- genistein, conventional surgery
- Where
- 5 sites in United States
- Volunteers
- 36 people
- Sponsor
- Northwestern University
Food Insecurity, Nutrition Assessment
Effect of Tailored Nutrition Plan Intervention on Children in Food Insecure Households.
The goal of this clinical trial is to evaluate the effectiveness of an individualized dietary intervention in reducing household food insecurity levels and improving growth metrics in Egyptian children aged 5 to 11 years from…
- Trial name
- NCT07722195
- Testing
- Tailored Nutritional Counseling, Standard Nutrition Education Group
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Kasr El Aini Hospital
Dizziness, Vertigo
Proof of Concept Study of EMBalance Decision Support System to Evaluate Balance Disorders
Balance is crucial for an individual's mobility and independence. Human balance is achieved and maintained by a complex set of sensorimotor systems that include sensory input from vision, proprioception and the vestibular system…
- Trial name
- EMBalance (NCT02704819)
- Testing
- Decision Support System (DSS), Specialist Audiovestibular Consultation, DSS Customised Vestibular Physiotherapy
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 200 people
- Sponsor
- University College, London
Sickle Cell Disease, Sickle Cell Crisis
A Comprehensive Care Plan for Pediatric Patients With Vaso-Occlusive Crises
Sickle cell disease (SCD) is the most common inherited blood disorder affecting 80,000 to 90,000 individuals in the United States.[10] There are 13,000 hospital admissions for a sickle cell crises, costing $448 million dollars…
- Conditions
- Sickle Cell Disease, Sickle Cell Crisis, Vaso-Occlusive Crises
- Trial name
- NCT02698761
- Testing
- Comprehensive Care Plan
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Valley Anesthesiology Consultants
Transition From Pediatric to Adult HIV Care
Planning the mPACT Trial - mHealth Strategies for the Pediatric to Adult HIV Care Transition
In contrast all other age groups, adolescents (age 10-19 years) have experienced constant, rather than declining, HIV-related mortality in the last decade.
- Trial name
- mPACT (NCT03876483)
- Testing
- Virtual peer support group
- Where
- Kenya
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Washington
Primary Care, Health Plan Implementation
Effectiveness of a Joint General Practitioner-Pharmacist Intervention on Benzodiazepine Deprescribing in the Elderly
Benzodiazepines or related drug (BZDR) are consumed for hypnotic or anxiolytic purposes in most cases. The consequences of BZDR are multiple with an increased risk of daytime sedation, balance disorders leading to falls and…
- Conditions
- Primary Care, Health Plan Implementation, Benzodiazepine Dependence, Elderly
- Trial name
- BESTOPH-MG (NCT05765656)
- Testing
- GP - pharmacist collaboration and pharmacist motivational interviewing
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Nantes University Hospital
Alzheimer Disease, Mild Cognitive Impairment
Implementation of AIP Services for Older Adults With AD
This study will longitudinally follow a cohort of older adults to better understand how decisions about aging in place or transitioning to long-term care-and the implementation of those decisions-are influenced by age-related…
- Trial name
- PYL-AIP (NCT07361601)
- Where
- United States
- Sponsor
- Northwestern University
CPR Decision-Making
Improving Decisions About CPR
Objective The primary objective is to evaluate the efficacy of a multi-faceted, clinical decision support intervention aimed at improving the quality of decisions about Cardio Pulmonary Resuscitation (CPR) for seriously ill…
- Trial name
- iCANACP (NCT03287895)
- Testing
- Decision Support
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Ottawa Hospital Research Institute
Asthma
Real World App-based CCAAP Management of Children With Asthma
This study is a multi-center randomized controlled trial of children with asthma. The objective of the study is to compare the App-based efficacy of China Children Asthma Action Plan (CCAAP) and written CCAAP used in management…
- Trial name
- NCT06112405
- Testing
- App-based CCAAP, Written CCAAP
- Volunteers
- 400 people
- Sponsor
- Beijing Children's Hospital
Neuromotor Impairments
Multicenter Study That Offers New Solutions for Paediatric Rehabilitation by Proposing a Rehabilitation Plan Based on Each Child's Needs Using New Technological and Robotic Devices, Combined Among Them.
The goal of this clinical trial is to demonstrate the efficacy of multi domain robotic and technological rehabilitation on everyday life and satisfaction in children with neuromotor conditions.
- Trial name
- MultiTECHChild (NCT06666829)
- Testing
- Multidomain intervention, Single domain intervention
- Where
- 6 sites in Italy
- Volunteers
- 194 people
- Sponsor
- IRCCS Fondazione Stella Maris
Obesity, Overweight
GoalTracker: Comparing Self-Monitoring Strategies for Weight Loss
This study is a randomized controlled trial that compares 3 self-monitoring approaches for weight loss. GoalTracker is a standalone, technology-based intervention using a commercial smartphone app (MyFitnessPal) and email.
- Conditions
- Obesity, Overweight, Weight Loss
- Trial name
- NCT03254953
- Testing
- self-monitoring of body weight, self-monitoring of diet, weekly personalized feedback + lessons + action plans
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Duke University
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