Clinical trials: Platelet Rich Fibrin
Lack of Keratinized Tissue, Mucogingival Surgery
Evaluation of the Effects of Injectable Platelet-Rich Fibrin and Hyaluronic Acid Treatments, Administered in Addition to Free Gingival Graft Therapy, on Clinical Healing.
The purpose of this clinical trial is to evaluate the effects of injectable platelet-rich fibrin (i-PRF) and hyaluronic acid (HA) gel on clinical healing and graft shrinkage when used in addition to Free Gingival Graft (FGG)…
- Conditions
- Lack of Keratinized Tissue, Mucogingival Surgery, Gingival Recession
- Trial name
- IPRF-HA-FGG (NCT07804888)
- Testing
- Free gingival graft, Free Gingival Graft with i-PRF, Free Gingival Graft with Hyaluronic Acid
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Saglik Bilimleri Universitesi
Acne Scars - Atrophic
Efficacy and Safety of Combined Nanofat Injection With Either Platelet Rich Fibrin or Microneedling Versus Nanofat Injection Alone in the Treatment of Facial Atrophic Post Acne Scars
To compare the efficacy and safety of combined nanofat injection with either platelet rich fibrin or microneedling versus nanofat injection alone in the treatment of facial atrophic post acne scars.
- Trial name
- NCT07471854
- Testing
- nanofat injecion, Platelet rich fibrin, Microneedling
- Volunteers
- 42 people
- Sponsor
- Assiut University
Maxillary Sinus
PRF Versus Advanced PRF in Sinus Augmentation
In the present study the main hypothesis , Advanced PRF will improve the bone quality and quantity in sinus augmentation
- Trial name
- NCT05134753
- Testing
- Advanced PRF, Control
- Volunteers
- 32 people
- Sponsor
- Cairo University
Jaw, Edentulous, Partially, Diabetes
Maxillary Sinus Floor Augmentation in Diabetic Patients
Placement of implants in diabetic patients is associated with higher risk of implant failure and peri-implant marginal bone loss due to an increased susceptibility to infections, impaired wound healing and associated…
- Trial name
- NCT04543630
- Testing
- Sinus floor augmentation
- Where
- 3 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- University of Copenhagen
Dental Implant, Implant Stability
Effect of L-PRF on Implant Stability and Marginal Bone Levels.
Osseointegration refers to the formation of a structure and functional bone-to-bone interface, without the interposition of soft tissue.
- Conditions
- Dental Implant, Implant Stability, Marginal Bone Levels, L-PRF
- Trial name
- NCT06516263
- Testing
- Leukocyte and platelet rich fibrin, Standard implant placement
- Where
- Ireland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dublin Dental University Hospital
Alveolar Bone Loss, Tooth Extraction
Evaluation of Stem Cell Exosomes Versus Platelet-Rich Fibrin in Tooth Extraction Socket Healing
This study evaluates two different treatments used to help the jawbone heal after a tooth is removed. When a tooth is extracted, the surrounding bone often shrinks, which can make it difficult to place dental implants later.
- Conditions
- Alveolar Bone Loss, Tooth Extraction, Bone Regeneration
- Trial name
- MSC-EXO vs PRF (NCT07508033)
- Testing
- MSC-Derived Exosomes, Platelet-rich fibrin (PRF)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al Salam University
To Evaluate the Clinical and Radiographic Effect of Platelet-rich Fibrin in Treatment of Necrotic Permanent Teeth with Open Apices
Evaluation of Platelet-rich Fibrin for Revascularization of Immature Permanent Teeth Versus Standard Apexification
The goal of this clinical trial is to evaluate the effect of platelet-rich fibrin for revascularization of immature permanent teeth in comparison to standard apexification using calcium hydroxide (as a 12 months follow up for…
- Trial name
- NCT06693349
- Testing
- the effect of platelet-rich fibrin in treatment of contaminated and uncontaminated immature permanent teeth, the effect of apexification in treatment of contaminated and uncontaminated immature permanent teeth
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Mohammed Nasser Alhajj
Diabetic Foot Ulcer, Type 1 Diabetes Mellitus
Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care.
The goal of this investigational study is to evaluate the safety and clinical performance of Tropocells Autologous Platelet-rich Fibrin (PRF) for wound care for both males and females, ages 18-80 years old, with Grade 1 and 2…
- Conditions
- Diabetic Foot Ulcer, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus (T2DM), Neuroischemic Foot Ulcer
- Trial name
- NCT06810726
- Testing
- Platelet Rich Plasma
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Estar Medical dba Medical Technologies, LTD
Endodontic Inflammation
Regenerative Endodontic Procedure of Immature Permanent Teeth With L-PRF: a Pilot Controlled, Clinical Trial
This study evaluates the impact of autologous 'leucocyte and platelet rich fibrin' (L-PRF) on the periapical bone healing and further root development of infected immature permanent teeth.
- Trial name
- NCT02437708
- Testing
- REP with L-PRF, REP, stem and progenitor cells
- Where
- 4 sites in Belgium
- Volunteers
- 29 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
A-PRF
Extraction and Socket Preservation Before Implant Placement Using Freezed Dried Allograft (FDBA) and Platelet-Rich Fibrin in Smokers
the investigators aim from this study to evaluate platelet rich fibrin potential to heal the periodontal tissue and to form new native bone in smokers that require socket augmentation following dental extraction and before…
- Trial name
- NCT05161455
- Testing
- platelet rich fibrin
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Saud University
Chronic Periodontitis
Benefits of Platelet Rich Fibrin In Mandibular Molar Furcation Defects
Background: Furcation is the bifurcation or trifurcation of a multirooted tooth. It is an area of complex anatomic morphology difficult to debride by routine periodontal instrumentation.
- Trial name
- PRFMMFD (NCT02430519)
- Testing
- Furcation treatment with PRF, Furcation Treatment with Allograft and GTR, allograft and guided tissue regeneration (GTR) membrane (DFDBM and Healiguide)
- Volunteers
- 22 people
- Sponsor
- Dr.Syed Asimuddin
Stage III Periodontitis
Injectable Platelet-Rich Fibrin (i-PRF) and Oxygen-Releasing Gel in the Treatment of Stage II Periodontitis.
Periodontitis is a chronic multifactorial inflammatory disorder affecting the periodontium, often implicated with microbial dysbiosis.
- Trial name
- NCT07859358
- Testing
- Injectable Platelet-Rich Fibrin (i-PRF, Peroxoborate Oxygen-Releasing Oral Gel, Sterile 0.9% Saline Solution
- Where
- 2 sites in Egypt
- Volunteers
- 24 people
- Sponsor
- Assiut University
Patients With at Least Single Missing Anterior Tooth, Thin Gingival Biotype
Clinical Evaluation of Platelet Rich Fibrin Versus Subepithelial Connective Tissue Graft for Soft Tissue Augmentation
Soft tissue biotype is a critical factor for success of implant in the esthetic zone . Different soft tissue augmentation techniques have been employed to increase soft tissue thickness such as: autogenous grafts, allografts…
- Trial name
- NCT03219944
- Testing
- Platelet Rich Fibrin, sub epithelial connective tissue graft
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Platelet Rich Fibrin vs Sub Epithelial Connective Tissue and Coronally Advanced Flap Alone in Gingival Recession
Gingival thickness plays a key role not only in the etiology but also in the treatment of gingival recessions. a thin marginal tissue lining the hard periodontal tissues seems to be one of the main risk factor for the onset of…
- Trial name
- NCT03712852
- Testing
- PRF+CAF treated patients, SCTG+ CAF treated patients, CAF treated patients
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Three Wall Intrabony Defects in Chronic Periodontitis
Platelet Rich Fibrin Combined With Simvastatin for Treatment of Intrabony Defect in Chronic Periodontitis
The purpose of the present study was to investigate the efficacy of autologous Platelet rich fibrin (PRF) or PRF and Simvastatin (SMV) with open flap debridement (OFD) in the treatment of three wall intrabony defects in…
- Trial name
- NCT02120872
- Testing
- Platelet rich fibrin and simvastatin, Platelet rich fibrin, Open Flap Debridement alone
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Periodontal Health
Effects of Platelet-rich Fibrin and Vitamin Dꝫ Injections on the Periodontal Health
The study aims to evaluate the effect of using PRF and vitamin Dꝫ injections on periodontal health and parameters and compare them when used to facilitate orthodontic treatment.
- Trial name
- NCT06223477
- Testing
- Platelet-rich Fibrin, Vitamin D3
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Beni-Suef University
Alveolar Osteitis
Alvogyl Versus Platelet-Rich Fibrin for Healing of Alveolar Osteitis
Alveolar osteitis, commonly known as dry socket, is a painful complication that can occur after tooth extraction, particularly following removal of a mandibular third molar.
- Trial name
- NCT07790653
- Testing
- Alvogyl Dressing, Platelet-Rich Fibrin (PRF)
- Where
- Pakistan
- Volunteers
- 102 people
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Root Resorption
Effects of Platelet-rich Fibrin and Vitamin Dꝫ Injections on Root Resorption
This study aims to investigate and compare the effect of PRF and vitamin Dꝫ injections on root resorption by using CBCT
- Trial name
- NCT06198322
- Testing
- Platelet-rich Fibrin, Vitamin D3
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Beni-Suef University
Gingival Recession
Clinical Evaluation of Two Different Surgical Techniques With PRF in the Treatment of Multiple Gingival Recessions
This prospective clinical study aims to evaluate and compare the effectiveness of coronally advanced flap (CAF) and tunnel techniques, both combined with platelet-rich fibrin (PRF), in the treatment of multiple Miller Class I-II…
- Trial name
- NCT06986525
- Testing
- CAF with PRF, Tunnel with PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Periapical Lesion
Guided Tissue Regeneration in Healing of Through and Through Periapical Lesion
Aim of this study is to evaluate the effect of i-PRF in the healing of through and through periapical lesion after periradicular surgery
- Trial name
- NCT04391725
- Testing
- Periapical surgery with guided tissue regeneration, Periapical surgery without anyguided tissue regeneration
- Where
- India
- Volunteers
- 32 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak