Clinical trials: Platelet Rich Fibrin
Gingival Recession, Generalized
Comparison of De-Epithelialized Gingival Graft With or Without Platelet Rich Fibrin in Multiple Gingival Recessions
The aim of this study is to compare the clinical efficacy and patient reported outcome measures of de-epithelialized gingival graft (DGG) with or without platelet rich fibrin on treatment of multiple adjacent gingival recessions…
- Trial name
- NCT06509867
- Testing
- DGG, Platelet rich fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Alveolar Ridge Preservation, Tooth Loss
Volumetric Efficacy of Alveolar Ridge Preservation
The goal of this clinical trial is to compare the effectiveness of four post-extraction socket management approaches in preserving alveolar ridge dimensions following tooth extraction in adults requiring implant-supported…
- Conditions
- Alveolar Ridge Preservation, Tooth Loss, Tooth Extraction, Tooth Extraction Site Healing
- Trial name
- ARP (NCT07812883)
- Testing
- Spontaneous Healing, d-PTFE Membrane, Leukocyte- and Platelet-Rich Fibrin (L-PRF)
- Where
- Chile
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Enterocutaneous Fistulas, Intra-abdominal Infection
Autologous Fibrin Glues for Fistulas Closure
Adjuvant use of fibrin glue in the fistula tract may promote healing in low-output enterocutaneous fistulas. However, there are only few studies that report autologous glue application in a larger patient group or…
- Trial name
- NCT01561066
- Testing
- Autologous platelet-rich fibrin glue (PRFG), Octreotide
- Where
- China
- Volunteers
- 122 people
- Sponsor
- Jinling Hospital, China
Alveolar Ridge Atrophy, Tooth Loss
Alveolar Ridge Splitting With Simvastatin/PRF Composite and Simultaneous Implant Placement
This randomized controlled clinical trial evaluated the effectiveness of platelet-rich fibrin (PRF) and a simvastatin/PRF composite combined with a xenogeneic bone graft during alveolar ridge splitting with simultaneous implant…
- Trial name
- ARS-SIMV (NCT07692620)
- Testing
- Alveolar Ridge Splitting with Simultaneous Implant Placement, Xenogeneic Bone Graft, Platelet-Rich Fibrin (PRF)
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Maruwan Ali Alteer
Periodontitis
PLATELET RICH FIBRIN COMBINED WITH 1.2% ATORVASTATIN FOR TREATMENT OF INTRABONY DEFECTS IN CHRONIC PERIODONTITIS
Current study was designed to evaluate the combined efficacy of PRF and 1.2% ATV gel with open flap debridement (OFD) in treatment of intrabony defects in chronic periodontitis subjects.
- Trial name
- NCT02119520
- Testing
- Platelet rich fibrin +Atorvastatin, Platelet rich fibrin, open flap debridement
- Where
- India
- Volunteers
- 96 people
- Sponsor
- Government Dental College and Research Institute, Bangalore
Gingival Recession
Platelet Rich Fibrin in the Treatment of Multiple Gingival Recessions
The aim of this randomized controlled clinical study is to evaluate and compare the effectiveness of platelet rich fibrin (PRF) and connective tissue grafts in the treatment of multiple gingival recessions.
- Trial name
- NCT02018120
- Testing
- connective tissue graft, platelet rich fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ege University
L-PRF, Dental Implants
Evaluation of the Effect of Leucocyte Platelet-Rich Fibrin (L-PRF) Technique Applied in Post-extraction Sockets Before Placement of Dental Implants
Aim of study: The application of L-PRF membrane in post-extraction sockets outmatches the use of a) allograft covered with a collagen fleece b) allograft combined with L-PRF membrane c) natural healing, with reference to bone…
- Conditions
- L-PRF, Dental Implants, Osseointegration, Alveolar Bone Grafting
- Trial name
- NCT07387913
- Testing
- Allograft and collagen membrane, Allograft and L-PRF membrane, L-PRF
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Ridge Splitting
Extended Platelet Rich Fibrin in Mandibular Alveolar Ridge Splitting
Thirty two healthy implants will be selected from the outpatient clinic of the oral and maxillofacial department of Mansoura university to be included in this study for replacement of lost posterior teeth with limited bone width.
- Trial name
- NCT06637982
- Testing
- ridge splitting with the use of allograft and pericardium membrane, ridge splitting with the use of extended platelet rich fibrin
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Periodontitis
Evaluation of L-PRF as an Antibiotic Slow-release Biological Device in the Treatment of Moderate Periodontitis
This study aimed to evaluate the efficacy of leukocyte platelet-rich fibrin (L-PRF) as a local sustained released device for antibiotics.
- Trial name
- NCT06153706
- Testing
- Subgingival application of L-PRF loaded with metronidazole, Subgingival application of L-PRF
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Yasmeen Khaled
Head and Neck Disorder, Free Flap
Platelet-Rich Fibrin in the Healing of Regional and Free Flaps
Determine if the use of platelet-rich fibrin (PRF) versus historical treatment methods improves the post-operative management of healing complications from flap donor sites.
- Trial name
- NCT04023474
- Testing
- Platelet Rich Fibrin (PRF) Application
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Florida
Periodontal Regeneration, Minimally Invasive Surgical Technique
Efficacy of the Entire Papilla Preservation Technique With and Without the Use of L-PRF as a Regenerative Material for the Treatment of Infrabony Defects
The goal of this clinical trial is to evaluate the efficacy of using L-PRF (leukocyte and platelet rich fibrin clot) as an autologous filling material in conjunction with the EPP (entire papilla preservation) technique for the…
- Conditions
- Periodontal Regeneration, Minimally Invasive Surgical Technique, Platelet Rich Fibrin, Microsurgery
- Trial name
- NCT06694168
- Testing
- Periodontal Regeneration, clinical and radiographic results, modified minimal invasive surgery, REGEND001 Autologous Therapy Product
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Universidad de los Andes, Chile
Alveolar Bone Loss
Biologically Oriented Alveolar Ridge Preservation (BARP) With and Without Advanced Platelet-Rich Fibrin Plus (A-PRF+)
Twenty patients were selected from the outpatient clinic of the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University seeking for extraction of non-restorable maxillary premolar teeth prior to…
- Trial name
- NCT07869082
- Testing
- Socket preservation by deproteinized bovine bone graft, socket preservation by deproteinized bovine bone graft mixed with advanced PRF+
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Gingival Recession
Biofunctionalization of a Volume-stable Collagen Matrix (VCMX) for the Treatment of Single Gingival Recession
The treatment of single gingival recessions comprises different well-established techniques, and the association between coronally advanced flap (CAF) and the subepithelial connective tissue graft is considered the gold standard.
- Trial name
- NCT05916742
- Testing
- CAF, i-PRF, VCMX
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Odontogenic Maxillary Cysts
Effect of Biphasic Bone Graft Material With Autologous Platelet-rich Fibrin on Bone Regeneration in a Maxillary Cyst
Effect of Biphasic Bone Graft Material (BGM) in combination with autologous platelet-rich fibrin (PRF) on bone regeneration in an odontogenic maxillary cyst: a randomized clinical trial
- Trial name
- NCT03003013
- Testing
- Biphasic Bone Graft Material (BGM) in Combination With Autologous Platelet-rich Fibrin (PRF)
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Periodontitis
Bone Morphogenetic Protein-2 In Grade II Furcation Defects.
The present study evaluated clinically and radiographically the regenerative potential of rhBMP-2 in absorbable sponge and PRF in Grade II furcation.
- Trial name
- NCT04372420
- Testing
- RhBMP-2 absorbable sponge in grade II furcation, PLATELET RICH FIBRIN in grade II furcation
- Where
- India
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Peri-Implant Tissues
The Effect of Injectable Platelet-Rich Fibrin in Peri-implant Soft Tissue
An inadequate amount of peri-implant soft tissue results in more plaque accumulation around the implants, peri-implant mucositis, marginal bone loss, mucosal recession, and/or attachment loss.
- Trial name
- NCT06753396
- Testing
- Platelet rich fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kutahya Health Sciences University
Tooth Mobility, Injectable Platelet-rich Fibrin
Evaluating the Effect of Injectable Platelet-rich Fibrin on Accelerating Orthodontic Tooth Movement
One of the main goals of orthodontic treatment is the reduction of treatment time through faster tooth movement. The previous studies evaluating platelet-rich fibrin (PRF) and orthodontic tooth movement (OTM) are limited, which…
- Trial name
- NCT06302296
- Testing
- injectable form of PRF
- Where
- Syria
- Volunteers
- 14 people
- Sponsor
- Hama University
Malocclusion, Angle Class II, Division 1
Efficacy of Biological Technique in Upper Canine Retraction and Levels of Discomfort
Twenty patients need therapeutic extraction of the maxillary first premolars with subsequent retraction of the maxillary canines, will be divided randomly into two groups, and will randomly assigned to one side of the maxillary…
- Trial name
- NCT03399422
- Testing
- i-PRF, canine retraction
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University
Osteoradionecrosis of the Jaw, Medicine Related Osteonecrosis of the Jaw
L-PRF in Prevention of ORN and MRONJ Following Tooth Extractions;v3.0
Osteoradionecrosis (ORN) and medication-related osteonecrosis of the jaw (MRONJ) are debilitating complications following dental extractions in patients who have received head and neck radiotherapy or antiresorptive therapy.
- Trial name
- NCT07585123
- Testing
- L-PRF, Standard Extraction
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Swansea Bay University Health Board
Sinus Perforation, Dental Implant Failure Nos
Guided Lateral Sinus Lifting Using Autologous Serum Albumin/Platelet-Rich Fibrin
This research aimed to evaluate the effect of an autologous Alb-PRF on bone regeneration after lateral sinus lifting via 3D volumetric analysis.
- Trial name
- NCT07348094
- Testing
- Guided Lateral Sinus Lifting with bone graft, Guided Lateral Sinus Lifting with Autologous Serum Albumin/Platelet-Rich Fibrin, Guided Lateral Sinus Lifting with sticky bone
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University