Clinical trials: Platelets Rich Plasma
Diabetic Foot Ulcer
Efficacy of Platelets Rich Plasma as a Therapeutic Tool in Diabetic Foot Ulcers
using platelet-rich plasma (PRP) in healing diabetic foot ulcers (DFUs), and to compare the rate of healing and final outcome with conventional therapy.
- Trial name
- NCT03890172
- Testing
- 20-100 ml venous blood will be drawn the from patient into sterilized centrifuge tube ,following centrifuge to separate PRP and at the bed side and tricked onto the ulcer twice weekly, standard treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Atrophic Acne Scar
Combined Procedures in the Treatment of Severe Acne Scars
Many methods utilize for acne scar treatment including laser, cosmetic filler, microneedling, local tumescent, Subcision and chemical peels. These procedures can be used individually or as a combination therapy.
- Trial name
- NCT06227481
- Testing
- Scar subcision, Platelet rich plasma injection, Polydioxanone mono threads insertion
- Volunteers
- 48 people
- Sponsor
- Al-Azhar University
Olfactory Dysfunction, Post-traumatic Olfactory Dysfunction
PANDORA: Evaluation of Platelet-rich Plasma in Non-tumoural Odour Disorders: a Descriptive Pilot Study.
This is a prospective, single-center, single-arm, non-comparative descriptive pilot study evaluating autologous platelet-rich plasma (PRP) injections in adults with persistent (>6 months) non-tumoural olfactory dysfunction…
- Conditions
- Olfactory Dysfunction, Post-traumatic Olfactory Dysfunction, Age-related Degenerative Olfactory Dysfunction
- Trial name
- PANDORA (NCT07473830)
- Testing
- Autologous Platelet-Rich Plasma (PRP) Injection
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Infertile Patients
the Effect of Hyaluronic Acid Intrauterine Wash on Endometrial Receptivity and Pregnancy Outcome
Hyaluronic acid intrauterine wash is done for infertile females undergoing intracytoplasmic sperm injection on the day of oocyte retrieval.
- Trial name
- NCT06937645
- Testing
- Hyaluronic Acid (HA), platlet rich plasma (PRP)
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- Al-Nahrain University
Epicondylitis
Platelet Rich Plasma (PRP) in Chronic Epicondylitis
Background Tendinopathy is a difficult problem to manage and can result in significant patient morbidity. Currently, the clinical use of PRP in painful tendons is widespread but its efficacy remains controversial.
- Trial name
- B-PRPtendon (NCT01945528)
- Testing
- US-guided tenotomy with PRP, US-guided tenotomy with lidocaine
- Where
- 2 sites in Spain
- Volunteers
- 86 people
- Sponsor
- Jose Ignacio Martin
Androgenetic Alopecia (AGA)
Clinical Study of PRP in the Treatment of Androgenetic Alopecia
A study on the therapeutic effect of platelet-rich plasma in the treatment of androgenetic alopecia
- Trial name
- NCT07551271
- Testing
- PRP
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Rotator Cuff Tears
Arthroscopic Rotator Cuff Repair Augmented With Platelet Rich Plasma
Purpose: To assess whether the use of platelet-rich plasma used as an adjuvant to arthroscopic rotator cuff repairs modify the rate of re-tears (measured by MRI) compared to a control group that only underwent the isolated…
- Trial name
- NCT04703998
- Testing
- Arthroscopic rotator cuff repair, platelet rich plasma
- Where
- Argentina
- Volunteers
- 103 people
- Sponsor
- Hospital Italiano de Buenos Aires
Urinary Incontinence
Platelet Rich Plasma (PRP) and High Intensity Focused Ultrasound (HIFU) in Management of Stress Urinary Incontinence (SUI): Pilot Study
Previous studies Results show (PRP) is safe and effective in treating SUI, other studies show the result of energy base devices (Co2 laser, HIFU) are effective in treating of SUI .
- Trial name
- NCT06691334
- Testing
- PRP injection, Hifu procedure and PRP injection
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Carpal Tunnel Syndrome, PRP
PRP as Adjuvant Treatment to CTR for Severe CTS Tunnel Syndrome
This study assesses the potential benefit of adjuvant platelet-rich plasma (PRP) with carpal tunnel release (CTR) for patients with severe carpal tunnel syndrome (CTS).
- Trial name
- NCT04811287
- Testing
- Carpal Tunnel Release with Platelet-Rich Plasma, Carpal Tunnel Release without Platelet-Rich Plasma
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Michael Fredericson, MD
Partial-Thickness Rotator Cuff Tear
Injection Therapies for Partial Rotator Cuff Tears
This completed study compared four injection treatments in patients with painful partial tears of the rotator cuff, the tendons that help move and stabilize the shoulder.
- Trial name
- NCT07871695
- Testing
- Autologous Platelet-Rich Plasma (PRP), Dextrose 15%, Betamethasone Sodium Phosphate and Betamethasone Acetate
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Diabetic Foot
A Randomized Trial on Platelet Rich Plasma Versus Saline Dressing of Diabetic Foot Ulcers
New treatments for persistent DFU have emerged, among which are the bioengineered skin substitutes, extracellular matrix proteins products, matrix metalloproteinases modulators, and growth factor therapy.
- Trial name
- NCT04090008
- Testing
- PRP gel, Saline dressing
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Mansoura University
Cesarean Section Complications, Uterine Bleeding
Platelet Rich Plasma for Uterine Scar
When vessel wall injury occurs, platelets become activated, releasing more than 30 bioactive proteins, many of which have a fundamental role in hemostasis, inflammation and ultimate wound healing.
- Conditions
- Cesarean Section Complications, Uterine Bleeding, Pelvic Pain, Menstrual Irregularity
- Trial name
- AA-PRP (NCT05224726)
- Testing
- Platelet Rich Plasma
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Androgenetic Alopecia, Alopecia
Study to Assess Efficacy of Platelet-Rich Plasma in Androgenetic Alopecia
The purpose of this study is to determine the efficacy of treatment with Platelet-rich plasma on Androgenetic alopecia (compared with placebo), between six months and baseline.
- Conditions
- Androgenetic Alopecia, Alopecia, Hair Loss
- Trial name
- PRP (NCT02393040)
- Testing
- PRP/Saline
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universitat Internacional de Catalunya
Photoaging
Effect of Platelet Rich Plasma on Photoaged Skin
The goal of this study is to assess the safety, tolerability and effectiveness of platelet rich plasma in the treatment of photoaged skin. This study will be divided into two parts.
- Trial name
- NCT01372566
- Testing
- Harvest PRP Separation System, Sterile Saline injection
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Poor Endometrium
Use of Platelet Rich Plasma (PRP) for Improving Thin Endometrium
Platelets rich plasma is simple source of growth factors and cytokines that can regulate endometrial growth for subgroup of thin endometrium women.
- Trial name
- PRPITM (NCT03166345)
- Testing
- Treatment of Thin Endometrium
- Where
- 2 sites in Egypt
- Volunteers
- 150 people
- Sponsor
- Ibn Sina Hospital
Tennis Elbow, Lateral Epicondylitis
Leukocyte-Poor Platelet-Rich Plasma Reduces Pain Symptoms in the Treatment of the Lateral Epicondylitis
Lateral epicondylar tendinopathy (LET), or tennis elbow, is a degenerative condition affecting the forearm's extensor tendons. It commonly leads to pain, reduced grip strength, and impaired function, particularly in individuals…
- Conditions
- Tennis Elbow, Lateral Epicondylitis, Lateral Epicondylitis (tennis Elbow), PRP Injection
- Trial name
- LET (NCT06854666)
- Testing
- effectiveness of platelet-rich plasma (PRP) in treating lateral epicondylar tendinopathy (LET)
- Where
- Poland
- Volunteers
- 72 people
- Sponsor
- Rehasport Clinic
Chronic Low Back Pain, Degenerative Disc Disease
Intra-discal Injection of Platelet-rich Plasma (PRP) Enriched With Exosomes in Chronic Low Back Pain
Intervertebral disc pathology accounts for 40% or more cases of chronic LBP. Available treatment options do not improve the underlying degenerative condition hence This indicates the need for new therapies.
- Trial name
- NCT04849429
- Testing
- Platelet rich plasma (PRP) with exosomes, Normal Saline
- Where
- 2 sites in India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Himanshu Bansal Foundation
Neuroma, Phantom Limb Pain After Amputation
Ultrasound-Guided Platelet-Rich Plasma Versus Local Anesthetic Injection for Chronic Neuroma Pain After Combat-Related Amputation
Patients with combat-related amputations frequently experience chronic neuroma pain that may interfere with rehabilitation, prosthesis use, mobility, sleep, and quality of life.
- Conditions
- Neuroma, Phantom Limb Pain After Amputation, Stump Pain, Platelet-rich Plasma (PRP)
- Trial name
- PRP-NEUROMA (NCT07624890)
- Testing
- Platelet-Rich Plasma (PRP) Injections, Local Anesthetic Injection
- Where
- 2 sites in Ukraine
- Volunteers
- 100 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Carpal Tunnel Syndrome
Platelet Rich Plasma and Perineural Injection Therapy for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy with involving compression of the median nerve in the carpal tunnel.
- Trial name
- NCT02696161
- Testing
- platelet rich plasma, 5% dextrose
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Low Back Pain, Sacroiliac Joint Synovitis
Treatment for Sacroiliac Joint Pain Using Platelet-rich Plasma (PRP) Versus Steroid/Anesthetic
The purpose of this study is to determine if platelet-rich plasma is superior to steroid/anesthetic for the treatment of sacroiliac joint pain.
- Trial name
- NCT05121961
- Testing
- Sacroiliac intra-articular injection
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Utah