Clinical trials: Platelets Rich Plasma
Platelet-Rich Plasma, Wound Healing Delayed
Influence of Platelet Concentrates on Wound Healing
Chronic soft tissues defects can extend into the fat layer or even deeper and can cause functional disadvantages. Split-thickness skin grafts (STSGs) used to cover these wounds have varying success rates.
- Trial name
- NCT03667638
- Testing
- Platelet-Rich Plasma
- Where
- Germany
- Volunteers
- 5 people
- Sponsor
- Hannover Medical School
Temporomandibular Joint Internal Derangement
Effect of Intraarticular Injection of Tenoxicam and Hyaluronic Acid Versus Platelet-Rich Plasma and Hyaluronic Acid in Temporomandibular Joint Internal Derangement
To compare the effect of intraarticular injection of Tenoxicam and Hyaluronic acid Versus Platelet-rich plasma and Hyaluronic acid in the management of patients with TMJ internal derangement with reduction.
- Trial name
- NCT06572904
- Testing
- Tenoxicam Injectable Product, Hyaluronic Acid 20 MG/1 ML Injection Gel/Jelly
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Platelets-rich Plasma, Osteoarthritis Knees Both
Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis
To evaluate the safety and effectiveness of PRP injection therapy in the repair of osteoarthritis and periarticular soft tissue injury through a single-center, exploratory clinical study, and to provide a more reliable basis for…
- Conditions
- Platelets-rich Plasma, Osteoarthritis Knees Both, Meniscus Disorder, Cartilage Injury
- Trial name
- NCT06082531
- Testing
- Sodium hyaluronate injection
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xijing Hospital
Carpal Tunnel Syndrome (CTS)
Carpal Tunnel Syndrome Treatment: Surgery Vs. Injections
This prospective randomized controlled study included 68 patients (aged 18-70) with mild to moderate carpal tunnel syndrome (CTS), randomized into three groups: surgical treatment (25 patients, 25 wrists), corticosteroid (CS)…
- Trial name
- NCT06852131
- Testing
- open carpal tunnel surgery, Steroid Injection, PRP injection
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ankara University
Shoulder Impingement Syndrome
Subacromial Injection of Allogeneic Platelet Rich Plasma (PRP) for Shoulder Impingement Syndrome
The purpose of this study is to investigate the efficacy of allogeneic PRP in patients with subacromial impingement disease
- Trial name
- NCT02019537
- Testing
- Steroid injection into the subacromial space, Allogeneic PRP injection into the subacromial space
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
TMJ Disc Disorder
Evaluation of Arthrocentesis With and Without PRP Injection in Patients With Disc Displacement With Reduction.
This study is aiming To evaluate the treatment effect (anti-inflammatory and healing ) of PRP with arthrocentesis versus arthrocentesis alone on the management of anterior disc displacement with reduction
- Trial name
- NCT05983653
- Testing
- arthrocentesis without PRP, arthrocentesis with PRP
- Where
- Egypt
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cairo University
Overactive Bladder Syndrome, Urinary Urge Incontinence
Platelet-Rich Plasma Versus Botulinum Toxin for Refractory Overactive Bladder: A Randomized Trial
Overactive bladder is a common condition that causes sudden urges to urinate, frequent urination, night-time urination, and sometimes leakage of urine.
- Conditions
- Overactive Bladder Syndrome, Urinary Urge Incontinence, Detrusor Overactivity
- Trial name
- NCT07184307
- Testing
- Platelet-Rich Plasma, Intravesical Botulinum Toxin Injection
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Benha University
Knee Chondropathy, Knee Early Osteoarthritis
Platelet-rich Plasma (PRP) vs Viscosupplementation for the Treatment of Early Knee Articular Degenerative Pathology
The investigators hypothesized that intra-articular injections of Platelet-rich Plasma (PRP) to treat knee degenerative articular cartilage pathology could determine pain relief and recovery of knee function with overall clinical…
- Trial name
- PRP-012 (NCT02135367)
- Testing
- PRP
- Where
- Italy
- Volunteers
- 185 people
- Sponsor
- Istituto Ortopedico Rizzoli
Ankle Osteoarthritis
A Single Intraarticular Injection of Platelet-Rich Plasma on Pain and Physical Function in Patients With Ankle OA
Platelet-rich plasma (PRP) has been reported to be an effective treatment for knee osteoarthritis (OA). The application in ankle OA has rarely been investigated.
- Trial name
- NCT04022928
- Testing
- PRP
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- Kaohsiung Veterans General Hospital.
De Quervain Tenosynovitis
Efficacy of Intralesional Platelet Rich Plasma in Patients of De Quervain's Tenosynovitis
De Quervain's tenosynovitis (DQT) was originally identified by Swiss surgeon Fritz de Quervain in 1895. It is a condition involving the entrapment of tendons within the first dorsal compartment of the wrist.
- Trial name
- NCT06651034
- Testing
- Platelet Rich Plasma
- Where
- Pakistan
- Volunteers
- 67 people
- Sponsor
- Muhammad Aamir Latif
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8
Platelet Rich Plasma for the Treatment of Genitourinary Syndrome of Menopause in Patients With Stage 0-III Breast Cancer
This phase I trial is to find out possible benefits and/or side effects of platelet rich plasma for the treatment of genitourinary syndrome of menopause in patients with stage 0-III breast cancer.
- Conditions
- Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8
- Trial name
- NCT04535323
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Therapeutic Autologous Platelet-rich Plasma
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Critical Limb Ischemia (CLI), Peripheral Vascular Disease (PVD)
Safety Study of Bone Marrow Cell Concentrate Prepared Using the Magellan System to Treat Critical Limb Ischemia (CLI)
The purpose of this study is to evaluate the safety of administration of marrow-derived autologous hematopoietic stem cells (HSC) concentrate and platelet-rich plasma (PRP) gel for the treatment of Critical Limb Ischemia (CLI).
- Trial name
- CLI (NCT01386216)
- Testing
- Magellan®
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Arteriocyte, Inc.
Osteoarthritis
Effectiveness of Stromal Vascular Fraction (SVF) and Platelet -Rich Plasma (PRP) in Patients With Knee Osteoarthritis: Study Protocol for a Phase III, Prospective, Randomized, Controlled Multi-center Study.
This multicenter, randomized, triple-blind, controlled trial, will enroll 108 patients who will block-randomized in a 1:1 ratio to either the intervention or control group.
- Trial name
- SPOST (NCT05660824)
- Testing
- Stromal Vascular Fraction infiltration, Plattelet Rich Plasma infiltration
- Volunteers
- 108 people
- Sponsor
- Adrien Schwitzguebel
Chronic Pain
Clinical Trial to Evaluate the Efficacy and Safety of Platelet-rich Plasma Infiltration in Chronic Omalgia
The experimental group will receive intralesional injections of platelet-rich plasma, evaluating its ability to relieve pain and provide sustained improvement through biological modulation of the joint and tendon environment.
- Trial name
- NCT07448285
- Testing
- Platelet-rich Plasma Local injection, betamethasone and Ropivacaine
- Where
- 2 sites in Spain
- Volunteers
- 86 people
- Sponsor
- Biobizkaia Health Research Institute
Osteoarthritis (OA)
Comparison of the Pain and Functional Improvement of Combined Extracorporeal Shockwave Therapy With or Without Intra-articular Hyaluronic Acid and Platelet-rich Plasma Injection on Advanced Osteoarthritis of the Knees.
This was a single group, double-blind, randomized clinical trial that enrolled 48 patients with Kellgren-Lawrence grade II to IV osteoarthritis of the knee.
- Trial name
- NCT07819955
- Testing
- Extracorporeal Shock Wave Therapy, Normal Saline, Hyaluronic Acid (HA)
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Chang Gung Memorial Hospital
Genitourinary Syndrome of Menopause
Efficacy of the Use of Cellular Matrix/ A-CP-HA Kit
This study is a randomized, controlled, non-inferiority trial, that will be performed on 192 women on Menopause (absence of menstruation for at least 12 months), with diagnostic of genitourinary syndrome of menopause (SGM) and a…
- Trial name
- CellularMatrix (NCT06425978)
- Testing
- Cellular Matrix / A-CP-HA Kit, Local estrogen therapy (Blissel, estriol 50 micrograms/g vaginal gel)
- Where
- Spain
- Volunteers
- 192 people
- Sponsor
- Fundación Santiago Dexeus Font
Tympanic Membrane Perforation
Efficacy of Platelet Enriched Plasma in Preventing Surgery for Patients With Chronic Tympanic Membrane Perforation
By doing this study, researchers hope to find out if platelet rich plasma (PRP) can heal holes in the eardrum as an alternative to surgery.
- Trial name
- NCT03837665
- Testing
- Platelet Rich Plasma
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Kansas Medical Center
Otitis Media Chronic, Temporal Bone
Efficacy of Platelet- and Extracellular Vesicle-rich Plasma in Chronic Postsurgical Temporal Bone Inflammations
This clinical study evaluates the efficacy of the autologous blood-derived product called platelet- and extracellular vesicle-rich plasma (PVRP) for the treatment of chronically inflamed post-surgical temporal bone cavities.
- Trial name
- PvRP-ear (NCT04281901)
- Testing
- Platelet- and extracellular vesicle-rich plasma, Standard conservative treatment
- Where
- Slovenia
- Volunteers
- 25 people
- Sponsor
- University Medical Centre Ljubljana
Osteoarthritis, Knee
Clinical Efficacy of Platelet-Rich Plasma and Hyaluronic Acid Versus Hyaluronic Acid for Knee Osteoarthritis With MRI Analysis
The study hypothesizes that the combination of Cellular Matrix PRP-HA is superior to Hyaluronic Acid (HA) alone, specifically from the Orthovisc Kit, in relieving pain and function associated with knee osteoarthritis.
- Trial name
- NCT06636695
- Testing
- Cellular Matrix, Orthovisc
- Where
- Singapore
- Volunteers
- 58 people
- Sponsor
- Changi General Hospital
Knee Osteoarthritis
Effectiveness of PRP, Conditioned Medium UC-MSCs Secretome and Hyaluronic Acid for the Treatment of Knee Osteoarthritis
The clinical trial will be carried out at the Dr. Moh. Hoesin Central Hospital, Palembang and planned from October 2022 to March 2023.
- Trial name
- NCT05579665
- Testing
- Platelet-rich Plasma, Conditioned Medium From Umbilical Cord Mesenchymal Stem Cell Culture (MSCs) Secretome, Low Molecular Weight Hyaluronic Acid
- Where
- Indonesia
- Volunteers
- 45 people
- Sponsor
- Universitas Sriwijaya