Clinical trials: Pneumonia; Pulmonary Infection
COVID-19, Infant, Newborn, Diseases
Long-term Respiratory Complications in Infants With Perinatal COVID-19
Study outcomes and endpoints: Primary outcome: to assess clinical characteristics of infants with confirmed COVID-19 infection at birth and to evaluate long-term respiratory consequences of neonatal COVID-19 infection.
- Conditions
- COVID-19, Infant, Newborn, Diseases, Respiratory Function Tests
- Trial name
- COLF (NCT05793723)
- Testing
- Pulmonary function testing device
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Covid19, SARS-CoV2 Infection
Monitoring the Effectiveness and Safety of COVID-19 Vaccines at National University of Colombia
There are relevant questions that need to be answered about the effectiveness and safety of COVID-19 vaccines. The objective of this observational study is to follow up the clinical outcomes after vaccination in all the…
- Trial name
- NCT04887246
- Testing
- COVID-19 vaccines
- Where
- Colombia
- Volunteers
- 4,078 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Covid19, Femur Fracture
Femoral frACturEs and COVID-19.
Retrospective cohort study comparing the early prognosis after surgically-treated proximal femur fragility fractures in patients affected and not affected by COVID-19.
- Conditions
- Covid19, Femur Fracture, Fragility Fracture
- Trial name
- FACE COVID-19 (NCT04657510)
- Testing
- COVID-19
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
SARS-CoV-2, Seasonal Influenza
A Study of Modified mRNA Vaccines in Healthy Adults
The main goal of this study is to evaluate the safety, reactogenicity, and immunogenicity of study vaccines.
- Conditions
- SARS-CoV-2, Seasonal Influenza, Respiratory Syncytial Virus, Cytomegalovirus
- Trial name
- NCT05397223
- Testing
- mRNA-1273, mRNA-1010, mRNA-1345
- Where
- 8 sites in United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Long COVID-19
Effects of Exercise Training on Patients With Long COVID-19
Effects of Exercise training on Patients With Long COVID-19, is a single-center, randomized, controlled trial designed to evaluate the effects of 4- week aerobic exercise administered to patients with long COVID-19 symptoms.
- Trial name
- NCT05961462
- Testing
- Exercise training
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Guangdong Provincial People's Hospital
COVID-19
COVID-19 Screening Program
In view of the recent COVID surge and difficulties in obtaining testing, we aim to increase Point of Care (POC) testing, whereby University of Pennsylvania (Penn) faculty, staff, and trainees who are working in person at Perelman…
- Trial name
- COVID SAFE 2 (NCT05216627)
- Testing
- Self-administered saliva-based viral testing
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Pennsylvania
Quality of Life, Injection Site Reaction
Simultaneous mRNA COVID-19 and IIV4 Vaccination Study
This study is a prospective, randomized clinical trial. During this study, participants will be randomly assigned to receive quadrivalent inactivated influenza vaccine (IIV4) and mRNA COVID-19 vaccine either simultaneously or…
- Conditions
- Quality of Life, Injection Site Reaction, Adverse Drug Event, Systemic Reaction
- Trial name
- NCT05028361
- Testing
- mRNA COVID-19, IIV4
- Where
- 3 sites in United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Duke University
Covid19
COVID-19 Vaccine Effectiveness in Albanian Health Workers
The purpose of this study is to evaluate the effectiveness of the COVID-19 vaccine in hospital based HWs in Albania. This will answer critical questions about the real-world performance of COVID-19 vaccines in one of the key…
- Trial name
- COVEAL (NCT04811391)
- Testing
- COVID-19 vaccine
- Where
- 3 sites in Albania
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Institute of Public Health, Albania
COVID 19
Comparison of Cardiopulmonary Fitness Level With Normal Values After COVID-19
COVID-19 (Coronavirus disease 2019) is a new infectious disease caused by a virus named as SARS-CoV2 (Severe Acute Respiratory Syndrome Coronavirus-2).
- Trial name
- NCT04753346
- Testing
- Physical Activity Level, Anxiety and Depression Assessment, Exercise Capacity
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Ankara University
Covid19, Nursing Home
Correlation Between the Incidence of COVID-19 in Nursing-homes and the Profile of Nursing Homes in the French Alps
Since the beginning of the COVID-19 outbreak in France, nursing homes (NH) have been heavily affected. In this study, the investigators want to evaluate the factors associated with the occurrence of COVID-19 epidemic clusters…
- Trial name
- PROCOPAD (NCT04695457)
- Where
- France
- Volunteers
- 74 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Coronavirus Infection, COVID-19
WGS Analysis of COVID-19 Positive Patients
We aim to better understand the mode of action of COVID-19 in the context of its interaction with the host genome through whole-genome sequencing.
- Trial name
- NCT04353401
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Vanda Pharmaceuticals
Covid19
OCTA Study: Retinal Vascular Changes in Patients With SARS-CoV-2 Infection
This study evaluates the retinal vascular features using optical coherence tomography angiography in patients that have been affected by COVID-19.
- Trial name
- NCT04601012
- Testing
- Optical coherence tomography angiography
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federico II University
COVID-19
Prevalence of DVT or PE in Patients Infected With COVID-19 Admitted to Hospital
The main objectives are: To establish the prevalence of deep venous thrombosis through ultrasonography in Patients infected with COVID-19 admitted to hospital. To identify patients with higher risk of deep venous thrombosis.
- Trial name
- SCREENING (NCT04380792)
- Where
- Spain
- Volunteers
- 2,497 people
- Sponsor
- Manuel Monreal
COVID-19, Cytokine Storm
CORONA: A Study Using DeltaRex-G Gene Therapy for Symptomatic COVID-19
COVID-19 is an infectious disease caused by severe acute respiratory syndrome coronavirus 2. COVID-19 causes life threatening complications known as Cytokine Release Syndrome or Cytokine Storm and Acute Respiratory Distress…
- Conditions
- COVID-19, Cytokine Storm, Acute Respiratory Distress Syndrome
- Trial name
- CORONA (NCT04378244)
- Testing
- DeltaRex-G
- Sponsor
- Aveni Foundation
COVID-19
Clinical Trial of Mycobacterium w in COVID-19 Positive Patients, Hospitalized But Not Critically Ill
This is a randomized, double blind, two arms, placebo controlled, clinical trial to study to evaluate the the safety and efficacy of Mycobacterium w in combination with standard of care versus placebo with standard of care for…
- Trial name
- NCT04358809
- Testing
- Suspension of heat killed (autoclaved) Mycobacterium w
- Where
- 4 sites in India
- Volunteers
- 480 people
- Sponsor
- Cadila Pharnmaceuticals
COVID-19, Acute Kidney Injury
Applying Artificial Intelligence to Identify Subphenotypes of Acute Kidney Injury in Mexican Patients With Severe COVID-19
The goal of this observational study was to identify subphenotypes of acute kidney injury patients with COVID-19, and the investigators analyzed their impact on mortality.
- Trial name
- IA-COVAKI (NCT06471101)
- Testing
- clusters
- Where
- Mexico
- Volunteers
- 2,934 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
COVID-19
A Phase 3 Randomized, Double-Blind Placebo Controlled, Multi-regional Trial to Evaluate the Efficacy and Safety of GT0918 for the Treatment of Mild to Moderate COVID-19 Male Patients
The purpose of this study is to assess the efficacy and safety of Proxalutamide (GT0918) in male outpatients with mild to moderate COVID-19 disease
- Trial name
- NCT04869228
- Where
- Brazil
- Volunteers
- 380 people
- Sponsor
- Suzhou Kintor Pharmaceutical Inc,
Hospital Acquired Pneumonia
Dexamethasone for Treating Severe Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype
Determine the efficacy of dexamethasone plus standard of care (SOC) as compared to placebo plus SOC for treating severe hospital-acquired pneumonia in critically ill patients with a proinflammatory phenotype; It's an…
- Trial name
- HAP-DEX (NCT06269900)
- Testing
- Dexamethasone
- Where
- 34 sites in France, Greece and 1 more
- Volunteers
- 450 people
- Sponsor
- Nantes University Hospital
COVID 19
Transpulmonary Pressure Measurements in Intubated Children With Covid-19 Respiratory Failure
The purpose of this study is to gather information to help doctors understand how Covid-19 affects the lungs in children.
- Trial name
- NCT04519411
- Testing
- Transpulmonary pressure measurements
- Sponsor
- Mayo Clinic
Breast Neoplasms
Prediction of Everolimus-induced Interstitial Lung Disease
The investigators will determine which factors are predictive for the development and severity of everolimus-induced interstitial lung disease and will develop a prediction model based on these risk factors.
- Trial name
- PREVENT (NCT01978171)
- Where
- 2 sites in Netherlands
- Volunteers
- 27 people
- Sponsor
- Radboud University Medical Center
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