Clinical trials: Point-of-Care Systems
Tuberculosis
Assessing Diagnostics At Point-of-care for Tuberculosis
Every year, more than 3 million people with TB remain undiagnosed and 1 million die. Better diagnostics are essential to reducing the enormous burden of TB worldwide.
- Trial name
- ADAPT (NCT05941052)
- Testing
- Tongue swab-based molecular assays
- Where
- 3 sites in Nigeria, Philippines and 1 more
- Volunteers
- 1,350 people
- Sponsor
- University of California, San Francisco
Dyspnea, Chronic Renal Failure
POCUS VS CT in Diagnosis of Acute Dyspnea in Chronic Hemodialysis Patients
Estimate the predictive value of POCUS in diagnosis of different causes of acute dyspnea in hemodialysis patients and compare between POCUS and CT in differentiation the causes of acute dyspnea in those population.
- Trial name
- NCT05729035
- Testing
- POCUS
- Volunteers
- 100 people
- Sponsor
- Randa Ahmed Sarhan
Point-of-care Ultrasound
Effects of Point-of-Care Ultrasound in Multidisciplinary Medical Wards
Point-of-care ultrasound (POCUS) is a bedside portable ultrasound technique utilized by healthcare providers to offer rapid and non-invasive diagnostic imaging.
- Trial name
- NCT06529315
- Testing
- Point-of-Care Ultrasound
- Where
- Taiwan
- Volunteers
- 144 people
- Sponsor
- National Taiwan University Hospital
Frail Elderly Patients, Geriatric Syndromes
Improving Care for Frail Older Adults Using a Digital Needs Assessment Tool
The goal of this trial is to evaluate whether a digital needs-assessment tool can improve care planning and outcomes for frail older adults (aged 60 years and above) hospitalized in Singapore.
- Conditions
- Frail Elderly Patients, Geriatric Syndromes, Frail Older Adults
- Trial name
- Frailty (NCT07580690)
- Testing
- Core: SST-informed care planning, Additional telephone calls
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- Duke-NUS Graduate Medical School
NSTEMI
Providing Rapid Out of Hospital Acute Cardiovascular Treatment (PROACT)
The purpose of this study is to determine if early diagnosis and risk stratification acquired through pre-hospital clinical assessment, 12-lead electrocardiogram and point of care biomarkers will facilitate enhanced triage and…
- Trial name
- PROACT (NCT01634425)
- Testing
- Alere Triage Meter Pro
- Where
- 5 sites in Canada
- Volunteers
- 601 people
- Sponsor
- University of Alberta
Staphylococcus Aureus
Methicillin-sensitive and Methicillin-resistant Staphylococcus Aureus (MSSA/MRSA) - Point-of-care-testing (POCT) in Clinical Decision Making
The study EPICS-6 consists of three study phases. Emergency Department patients are screened for nasal and pharyngeal colonisation with Methicillin sensitive and Methicillin resistant Staphylococcus aureus (MSSA/MRSA) using a…
- Trial name
- EPICS-6 (NCT03220386)
- Testing
- Decolonization by nasal Octinidin treatment and skin washings
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Charite University, Berlin, Germany
Neurologic Findings
Handheld Point of Care Electro-Diagnostic Device
There are currently several products offering POC EEG, intended to be deployed on each patient individually and continuously. The investigators propose studying a different approach by using a migrating POC electrodiagnostic…
- Trial name
- NCT07223827
- Testing
- POC EEG
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Indiana University
Anticoagulation and Thrombosis Point of Care Test (AT-POCT)
Point of Care Testing to Improve Monitoring of LVAD Patients
The purpose of this study is to develop and validate the accuracy of a low-cost "point-of-care" test (POCT) that allows monitoring of markers for anticoagulation and thrombosis (local coagulation or clotting of the blood), to be…
- Trial name
- NCT03555552
- Testing
- Anticoagulation and Thrombosis Point of Care Test(AT-POCT), Duke Central Automated Laboratory (DCAL)
- Where
- United States
- Sponsor
- Duke University
Type II Diabetes Mellitus
A Study to Evaluate the Effect of a Digital Disease Management Tool in Patients With Type 2 Diabetes Mellitus
A real-world, point-of-care, randomized, parallel group, open, 6-month clinical study to evaluate if the provision of a digital disease management tool improves glycaemic control in participants with type 2 diabetes mellitus…
- Trial name
- NCT02749435
- Testing
- Use of digital disease management tool in participants with T2DM
- Where
- 14 sites in United Kingdom
- Volunteers
- 57 people
- Sponsor
- AstraZeneca
Abortion Early
Point of Care Tests in the Management of Very Early Medical Abortion
This study will investigate the use of a point of care test in patients who are having an abortion at a gestation of <6 weeks (known as a very early medical abortion).
- Trial name
- POCT VEMA (NCT07417787)
- Testing
- Blood test, Participant Questionnaire
- Where
- 3 sites in Sweden, United Kingdom
- Volunteers
- 130 people
- Sponsor
- University of Edinburgh
Acute Decompensated Heart Failure (ADHF)
Bedside NT-proBNP Monitoring in Acute Heart Failure
The goal of this observational study is to investigate the association between dynamic changes in NT-proBNP levels and clinical decongestion status in patients with acute decompensated heart failure (ADHF) receiving…
- Trial name
- NCT07762521
- Testing
- Serial NT-proBNP Measurement
- Volunteers
- 50 people
- Sponsor
- Mao Chen
Cardiac Disease
A Multi-Center Study of Detection of Low Ventricular Ejection Fraction
This is a multi-site, retrospective study to evaluate the performance of a locked AI-based algorithm for detection of left ventricular systolic dysfunction.
- Trial name
- NCT04963218
- Testing
- AI Algorithm to detect LVEF in ECG
- Where
- 4 sites in United States
- Volunteers
- 16,000 people
- Sponsor
- Mayo Clinic
Urinary Tract Infections
Diagnostic Accuracy of Point of Care Test of First Voided Urine Compared to Midstream Voided Urine in Primary Care
The aim of this study is to determine if sampling technique of urine affects diagnostic modalities in primary care. Furthermore it aims to determine if there is difference in the accuracy of the point-of-care test, when the urine…
- Trial name
- NCT02585115
- Where
- Denmark
- Volunteers
- 117 people
- Sponsor
- University of Copenhagen
Syphilis, HIV Infections
Syphilis and HIV Point of Care Testing (POCT) in Saskatchewan
The goal of this clinical trial is to learn about Syphilis and HIV point of care testing among inner city, remote, rural and hard to reach populations in Saskatchewan. The main question[s] it aims to answer are: 1.
- Trial name
- SHIVER (NCT05863117)
- Testing
- Reveal Rapid TP (from MedMira)
- Where
- 2 sites in Canada
- Volunteers
- 1,650 people, healthy volunteers welcome
- Sponsor
- Wellness Wheel Medical Clinic
HIV
Operational Assessment of Point-of-Care Diagnostics in Primary Healthcare Clinics
Diagnostic point-of-care (POC) tests are being rapidly developed and implemented in resource-limited settings. There has been a rapid rise of HIV and TB POC tests in South Africa during the last 10-15 years.
- Trial name
- NCT02692274
- Where
- South Africa
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- University of KwaZulu
Cardiac Anomalies
Prospective Evaluation of Cardiac Point-of-Care Ultrasound (POCUS) Performed by PEM Fellows and Artificial Intelligence on Children With Pre-existing Cardiac Conditions.
The goal of this study is to prospectively assess the diagnostic agreement of PEM fellow-performed cardiac POCUS and of AI-assisted interpretation using the Exo Iris probe, as compared to a complete echocardiography for detecting…
- Trial name
- POCUS-AI PEM (NCT07503158)
- Testing
- AI Pocus_Cardiac
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Nicklaus Children's Hospital f/k/a Miami Children's Hospital
Acute Myocardial Infarction
Rapid Delivery of Autologous Bone Marrow Derived Stem Cells in Acute Myocardial Infarction Patients.
The primary objective of the study is to determine the feasibility and safety of intracoronary administration of autologous bone marrow derived mononuclear cell product in patients at risk for clinically significant cardiac…
- Trial name
- AMIRST (NCT01536106)
- Testing
- Autologous Bone marrow mononuclear cells
- Where
- 3 sites in India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- TotipotentRX Cell Therapy Pvt. Ltd.
Meningitis, Meningococcal, Meningococcal Sepsis
Petechiae In Children (PIC) Study: Defining A Clinical Decision Rule for The Management Of Fever and Non-Blanching Rashes In Children Including The Role Of Point Of Care Testing For Procalcitonin & Neisseria Meningitidis DNA.
A fever and a non-blanching rash is a relatively common reason for a child to attend an emergency department. A fever and a non-blanching rash can be an early sign of a life-threatening infection known as meningococcal disease.
- Conditions
- Meningitis, Meningococcal, Meningococcal Sepsis, Meningococcal Disease, Meningococcal Infections
- Trial name
- PIC (NCT03378258)
- Where
- United Kingdom
- Volunteers
- 1,329 people
- Sponsor
- Belfast Health and Social Care Trust
Burns, Contracture Scar
Autologous Point-of-Care Adipose Therapy: Delayed Injury/Scar
The goal of this study is to explore if an adipose-based therapeutic strategy can treat contracted scars secondary to soft-tissue burn wounds in injured individuals, especially those with severe burns or soft-tissue loss.
- Conditions
- Burns, Contracture Scar, Surgical Injury
- Trial name
- NCT06857435
- Testing
- Full Thickness Skin Graft (FTSG), Base of wound fat graft with Split Thickness Skin Graft (STSG) Reconstruction (Autologous Layered Composite Grafting).
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Acute Coronary Syndromes (ACS), Troponin I
Effect of Point-of-care Analysis of Ultrasensitive Troponin I on Length of Hospital Stay in Patients With Cardiac Chest Pain (POC Troponina)
This clinical study aims to compare two different methods for measuring high-sensitivity troponin I, a key biomarker used to diagnose heart attacks.
- Conditions
- Acute Coronary Syndromes (ACS), Troponin I, Point-of-Care Testing
- Trial name
- POC Troponina (NCT06861582)
- Testing
- Point-of-care ultrasensitive troponin testing, Laboratory-based ultrasensitive troponin testing
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo
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